Nek7 (NIMA-related kinase 7) - Rat Genome Database

Name: Nek7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Nek7 (NIMA-related kinase 7) Rattus norvegicus

Analyze

Symbol:

Nek7

Name:

NIMA-related kinase 7

RGD ID:

1311160

Description:

Exhibits protein serine/threonine kinase activity. Predicted to be involved in positive regulation of DNA metabolic process and protein phosphorylation. Predicted to localize to cytoplasm and nucleoplasm. Orthologous to human NEK7 (NIMA related kinase 7); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC360850; never in mitosis A-related kinase 7; NIMA (never in mitosis gene a)-related expressed kinase 7; NIMA (never in mitosis gene a)-related kinase 7; nimA-related protein kinase 7; serine/threonine-protein kinase Nek7

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NEK7 (NIMA related kinase 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Nek7 (NIMA (never in mitosis gene a)-related expressed kinase 7)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Nek7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NEK7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NEK7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nek7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NEK7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NEK7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nek7 (NIMA related kinase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NEK7 (NIMA related kinase 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Nek7 (NIMA (never in mitosis gene a)-related expressed kinase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	nek7 (NIMA-related kinase 7)	Alliance	DIOPT (PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	nekl-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	50,022,212 - 50,149,374 (-)	NCBI
Rnor_6.0 Ensembl	13	55,488,531 - 55,561,750 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	55,485,759 - 55,617,534 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	60,515,259 - 60,641,914 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	51,679,191 - 51,942,636 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	51,696,338 - 51,802,947 (-)	NCBI
Celera	13	50,308,775 - 50,377,141 (-)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Weight Gain (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (EXP,ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

methapyrilene (EXP)

nickel atom (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

raloxifene (ISO)

rimonabant (ISO)

silicon dioxide (ISO)

sulindac (EXP)

tamoxifen (ISO)

testosterone (EXP)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of telomerase activity (IEA,ISO)

positive regulation of telomere capping (IEA,ISO)

positive regulation of telomere maintenance via telomerase (IEA,ISO)

protein phosphorylation (IEA,ISO,ISS)

Cellular Component

cytoplasm (IEA,ISO,ISS)

microtubule organizing center (IEA)

nucleoplasm (IEA,ISO)

nucleus (ISO,ISS)

spindle pole (IEA)

Molecular Function

ATP binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IDA,IEA)

protein threonine kinase activity (IEA)

References

References - curated


1.	Belham C, etal., Curr Biol. 2001 Aug 7;11(15):1155-67.
2.	MGD data from the GO Consortium
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12840024	PMID:21531765	PMID:26188091	PMID:31505169

Genomics

Comparative Map Data

Nek7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	50,022,212 - 50,149,374 (-)	NCBI
Rnor_6.0 Ensembl	13	55,488,531 - 55,561,750 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	55,485,759 - 55,617,534 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	60,515,259 - 60,641,914 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	51,679,191 - 51,942,636 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	51,696,338 - 51,802,947 (-)	NCBI
Celera	13	50,308,775 - 50,377,141 (-)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

NEK7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	198,156,994 - 198,322,420 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	198,156,998 - 198,322,420 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	198,126,128 - 198,291,550 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	1	198,126,108 - 198,291,550 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	196,468,306 - 196,555,392 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	194,933,338 - 195,020,426	NCBI
Celera	1	171,248,701 - 171,414,114 (+)	NCBI
Cytogenetic Map	1	q31.3	NCBI
HuRef	1	169,281,535 - 169,446,709 (+)	NCBI		HuRef
CHM1_1	1	199,548,440 - 199,713,855 (+)	NCBI		CHM1_1

Nek7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	138,411,575 - 138,547,495 (-)	NCBI	GRCm39		mm39
GRCm38	1	138,483,837 - 138,619,757 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	138,482,875 - 138,620,141 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	140,381,291 - 140,516,273 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	140,301,125 - 140,436,107 (-)	NCBI			mm8
Celera	1	141,116,690 - 141,252,989 (-)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	60.82	NCBI

Nek7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	34,626,494 - 34,717,546 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	34,575,292 - 34,714,024 (+)	NCBI	ChiLan1.0	ChiLan1.0

NEK7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	178,063,721 - 178,228,197 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	178,138,925 - 178,228,197 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	173,752,892 - 173,918,258 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

NEK7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	7	4,555,231 - 4,704,955 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	7	4,557,754 - 4,755,912 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Nek7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936567	5,685,619 - 5,815,094 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEK7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	20,997,243 - 21,124,283 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	20,966,660 - 21,124,283 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	25,627,135 - 25,785,075 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEK7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	31,111,332 - 31,257,445 (-)	NCBI
ChlSab1.1 Ensembl	25	31,110,616 - 31,257,374 (-)	Ensembl

Nek7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624798	2,116,888 - 2,283,061 (-)	NCBI

Position Markers

BF386197

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	13	55,502,217 - 55,502,372	NCBI	Rnor6.0
Rnor_5.0	13	60,531,717 - 60,531,872	UniSTS	Rnor5.0
RGSC_v3.4	13	51,696,144 - 51,696,299	UniSTS	RGSC3.4
Celera	13	50,322,354 - 50,322,509	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH136376

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	13	55,487,621 - 55,487,887	NCBI	Rnor6.0
Rnor_5.0	13	60,517,121 - 60,517,387	UniSTS	Rnor5.0
RGSC_v3.4	13	51,681,295 - 51,681,561	UniSTS	RGSC3.4
Celera	13	50,307,811 - 50,308,077	UniSTS
Cytogenetic Map	13	q13	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	107975663	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	12193394	108478121	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	14096330	59096330	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	14096330	59096330	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	19810814	64810814	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	20052477	65052477	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	21482481	58537177	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	24502279	108770533	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	28008338	73008338	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	28584452	73584452	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	29076934	74076934	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	29076934	74076934	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	35301263	107975663	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	36147533	64868393	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	36147533	99968921	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	37346348	82346348	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39372927	84372927	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39501300	93652524	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	42310744	86833540	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	42310744	87310744	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	43575717	88575717	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	45676629	90676629	Rat
6893344	Cm79	Cardiac mass QTL 79	1.5	0.04	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	49058507	67207219	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	51080989	96080989	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	51569248	96569248	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	51577824	90675199	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	121
Count of miRNA genes:	99
Interacting mature miRNAs:	106
Transcripts:	ENSRNOT00000000817
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	42	50	34	19	34	8	11	74	35	37	11	8
Low		1	7	7		7					4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000000817 ⟹ ENSRNOP00000000817

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	13	55,488,585 - 55,561,726 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000090162 ⟹ ENSRNOP00000069169

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	13	55,488,531 - 55,561,750 (-)	Ensembl

RefSeq Acc Id:

NM_001108346 ⟹ NP_001101816

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	50,025,038 - 50,093,465 (-)	NCBI
Rnor_6.0	13	55,488,585 - 55,561,726 (-)	NCBI
Rnor_5.0	13	60,515,259 - 60,641,914 (-)	NCBI
RGSC_v3.4	13	51,679,191 - 51,942,636 (-)	RGD
Celera	13	50,308,775 - 50,377,141 (-)	NCBI

Sequence:

show sequence

ATGGATGAACAACCACAAGGAATGCAAGGGCCCCCTGTTCCTCAGTTCCAGCCGCAGAAGGCAT
TACGACCAGATATGGGCTATAATACTTTAGCCAACTTCCGAATAGAAAAGAAAATTGGACGTGG
ACAATTTAGTGAAGTTTATAGAGCATCCTGTCTCCTGGATGGAGTTCCAGTAGCTTTAAAAAAA
GTGCAGATATTTGATTTAATGGATGCCAAAGCACGTGCCGATTGTATCAAAGAAATAGATCTCC
TTAAGCAACTCAACCATCCAAATGTAATTAAATATTATGCATCATTCATTGAAGATAATGAGCT
GAACATAGTTTTGGAGTTAGCAGATGCTGGTGACCTCTCCAGAATGATAAAGCACTTTAAGAAA
CAAAAGAGGCTAATCCCTGAGAGGACTGTTTGGAAATACTTCGTTCAGCTCTGCAGTGCACTGG
ACCACATGCATTCTCGAAGAGTCATGCACAGAGATATAAAACCAGCTAATGTGTTCATTACAGC
CACTGGGGTAGTCAAACTTGGAGATCTTGGACTTGGTCGGTTCTTCAGCTCCAAAACCACAGCT
GCACATTCTTTAGTGGGCACGCCTTACTACATGTCTCCAGAGAGGATCCATGAGAACGGATACA
ACTTCAAGTCTGACATCTGGTCTCTCGGCTGTCTGCTGTATGAGATGGCGGCGTTGCAGAGTCC
TTTCTACGGAGACAAGATGAATCTGTACTCTCTGTGTAAGAAGATAGAACAGTGTGACTACCCA
CCTCTCCCATCAGATCACTATTCCGAGGAGCTCCGACAGTTAGTTAATATATGCATCAACCCAG
ATCCGGAGAAGCGACCGGACATCGCCTACGTTTATGATGTGGCAAAGAGGATGCATGCCTGTAC
CGCCAGCAGCTAA

hide sequence

RefSeq Acc Id:

XM_006249926 ⟹ XP_006249988

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	50,022,212 - 50,149,369 (-)	NCBI
Rnor_6.0	13	55,485,759 - 55,617,533 (-)	NCBI
Rnor_5.0	13	60,515,259 - 60,641,914 (-)	NCBI

Sequence:

show sequence

CCTCGGGGATGCCGGGATGTTTACCCTCCTGACAGCCGCGGCAGCCGGAGGAGGAGCACAGCCG
GGAGGATGGGCCGCTGCTAGGCTCGCAGTGGGAAGCGCCGGCCGATCAGGGTGGGAGCCGGCGC
TTGCAGTGGCGCGGGCAGAGGCGATCGGCCCGGGATCGCGCAGCCCTGCAGCCCGCGTGGATCG
AGCTGCCCGGGCGCCCTGAATCCTCAAGTCCCAGTTGAGTCAGAATGGATGAACAACCACAAGG
AATGCAAGGGCCCCCTGTTCCTCAGTTCCAGCCGCAGAAGGCATTACGACCAGATATGGGCTAT
AATACTTTAGCCAACTTCCGAATAGAAAAGAAAATTGGACGTGGACAATTTAGTGAAGTTTATA
GAGCATCCTGTCTCCTGGATGGAGTTCCAGTAGCTTTAAAAAAAGTGCAGATATTTGATTTAAT
GGATGCCAAAGCACGTGCCGATTGTATCAAAGAAATAGATCTCCTTAAGCAACTCAACCATCCA
AATGTAATTAAATATTATGCATCATTCATTGAAGATAATGAGCTGAACATAGTTTTGGAGTTAG
CAGATGCTGGTGACCTCTCCAGAATGATAAAGCACTTTAAGAAACAAAAGAGGCTAATCCCTGA
GAGGACTGTTTGGAAATACTTCGTTCAGCTCTGCAGTGCACTGGACCACATGCATTCTCGAAGA
GTCATGCACAGAGATATAAAACCAGCTAATGTGTTCATTACAGCCACTGGGGTAGTCAAACTTG
GAGATCTTGGACTTGGTCGGTTCTTCAGCTCCAAAACCACAGCTGCACATTCTTTAGTGGGCAC
GCCTTACTACATGTCTCCAGAGAGGATCCATGAGAACGGATACAACTTCAAGTCTGACATCTGG
TCTCTCGGCTGTCTGCTGTATGAGATGGCGGCGTTGCAGAGTCCTTTCTACGGAGACAAGATGA
ATCTGTACTCTCTGTGTAAGAAGATAGAACAGTGTGACTACCCACCTCTCCCATCAGATCACTA
TTCCGAGGAGCTCCGACAGTTAGTTAATATATGCATCAACCCAGATCCGGAGAAGCGACCGGAC
ATCGCCTACGTTTATGATGTGGCAAAGAGGATGCATGCCTGTACCGCCAGCAGCTAAACTGTAC
GAGACCCTGAAGACGGCGACTTAAATAACTTAAAAGTGTTTTTGTGCAAATCATACCTCCCCGC
TTTTGTCTGGGTGTTAAGATTACTATTTCAGAGCTAATGCGCTTTGAATCCTTAACCAGTTTTC
ATATGAGCTTCATTTTCTACCAGGCTCAGTCACCTTCCCAACCCCCAACTCTGGGATGCTCAGA
TTGCATCAAGGACGCAAGCACAAGAGGTTTTAAGGGCGTAAGGTTTGAGAATTGTTTAGCGTTT
CTGCTGAGAGATTGTGTTTCTAGATAGTAAGTGCCAGGTGGAGGAGGACACAGAGGCACTGTCT
GGAGGGAGGAGGCAGAACCCGAGGAAAGACCTGAGCATGTGACACGTTTGTTTTTAAGTCACTT
AACGGACATCCTAGTGGACATAATTGTGAAGTTCTTTGTTTTTTTTTAAGTTTGAAGTACATGT
TTTATTTAGTTCTTAGCATTATAGTTTTCGAATATAATTCTTATACTAAATGCAGACATGAACT
TTTGAGAAAGATTGAAAATTTTTAGTTTATACACTCAAAATGCAACTATTAAATGTGAAAACAT
AGAGGACGAAATGTGAGTTGGACACTGAAAGTCTCGTGTTTTAATGCCTTTGAAAGCCTTTTTG
TGTTTAAATGGTGTGAATGAAGCCATTTTAAAAGTGGTTAAGGACTTGTTTGCCTGGCGTGATA
GTCATTTTTAAAGTTGCACATTGCTCAAGGCTTTGTGTTCTTACTGTACATTTGAAGAATATTC
TGGAATAATCTTGTAGTAACTATAGTTCAATTTCTTTACAAATCTAAATACACTTAACTCATAG
CTATACACTGTAATGTAAGTGTATATTTTTATTCATATATTGAATGAAGTTTTGATCAGTTCCC
CTTCAGAATTTTTTTTTATTCAAGTTACTTTCTTATTTATATTGTGTGTGCATTTTATCCACTA
AATGTTTCAGATTCTCTGACAACGAACTCCCTTTGTAAAAGAGATTTGGTATGCCAACACTTTT
CTTAGATTGAAACTTTTTTTAAAAAACTTTTGGGCCATTCTGTGTGCATCTGTTTTATCTTGTT
AGGAAGAGAAGATGTATGTTAAAATGTGCCTGTGGATGTCGATGTTGTTTGACAGGGTTATAAT
TTTAGAGTATGTGTAAGGCCATGGAGACTGGCCCTTAATAGACAGAACCATTAGGAGAGCAGCG
TTTCTGTGGAGACACTTTGGAGTAAAGTACTATATTTGTGTATGAAGATGACAGACATGGGTGA
TGCTCATTTTAGTTAAGAAAAAAATATAAAAAGGAGAGCTATTTAGGAAACCCTGAGGTGGAAT
TTGTTTTCCCTGAATGTCTTCATCTTAATACCAACCAGTGTCTTGAAAGACTTGTGGAGCCAAA
GAACAGAGCGGCCGTGGCGGTTGCAGAACACTGTGTCCCATGATTGAACATTGGGAAGGCTTAT
CCTGCTGGTGGGGCAGCTTGTACTGTGGCCAAAAGAGCTCTTGGGTTTGTTTTCTCACAGAGTA
TTCTTTCTATAGTTATTGTCAAGCAATCTGTAAGTTTTCAAAATAGTGGCTCGTCTTTTAATTG
GCTGTGCTTGCTGTCTTAGACAAGGGACATCTGGTTGGTTTTTCATCCTGAAGGCTGAACTGGG
TGTGTCCCAGATCTTAGTGGCTCAGAGCATTTATCCAGAGGCGTGAAGAAAGCTGCTTCTGGCG
ACCATTTATTTGTATTGTGCTATGTCCACTCTAATGTCACAGGACTGACCGAGATGCAATATCC
CCTGCCTACAAGAGTCATTTTCTTTCCATCTTTGAAAACAAAAGGTTCTGCCCGGCATTGGTGG
TGCATACTTTTAATCTCAGCACTTGGAGGGCAGAGGCAGGTGGATCTCTATGAGTTCCAGGACA
GCCTGGGCTACACAGAGAAAAGCCTATCTCAAAAAAACCAAAACCGAATCAATGAAAATACAAG
GCTTATCCCTTGTAGTGATTTTGCTTTGTGAATCGGTCTTCTAAAAAATGGGGGAGGGGGACTG
GGGGGAGCTGGAGACCTTAATGGTTAGGGATGGTCACTGTCCTTTAGTCCAAGTGTTCATATCC
ACCCCACCTCCAAAGAATCTACTGTGTAACAATAAATTCAGTGTGATATTTGCAAATGGTTATG
GAGTTGATTAGAATTTCTAATCTTAACCATCACCTATAAAATATACTCTTTATATTTCTGTTTA
TGAGTAATTTGATATGAAGTTGAATGTTGGAACTGAACTGATTTGAGTAACAGGTCAAATTAAA
GGTACGGCTGATTTGAAACCTTGCTTGAACATTGGTACTAGTTACCCAGGGGAAAATGGGCAGT
AACTGCGGTTGGCACGCTGAGGTATGGGGTGGTGAATGTAGGGTAGCCTCATCTGCAGTGCTCA
AAAAGGTCTAATGATTGTAGAGCTAGCAAGATGCCGCTGCCAAGTCAAGAGCGCTCTACCGTTC
CTAAGTGCGTCCATTACAAAACACCTGTCTTGTATCCGTAAACTCCAGGTGTTGCTCTTAACCT
GTCCTGTATTTATTATAGCCAAGAAGCTGTTATTCACACAGATTATTCTTTTGAATCGAATGTA
TTGTTCATCACCCACAAGTGCACACTCTTTGCCTCTGATCCCCACAGTACTGTAATATGAATTT
CTTTTGTGAAATACGTTTTATTTTGTTATGCTTTAAATGTACATGCAAGAGAACTCTGTTATTA
GCTTCAGAAACTGTACAATATCGTAATATAAATATATAAAAATAAAAGATGAGTACTGTAAGTT
TGA

hide sequence

RefSeq Acc Id:

XM_017598846 ⟹ XP_017454335

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	55,485,759 - 55,617,534 (-)	NCBI

Sequence:

show sequence

TCCTCGGGGATGCCGGGATGTTTACCCTCCTGACAGCCGCGGCAGCCGGAGGAGGAGCACAGCC
GGGAGGATGGGCCGCTGCTAGGCTCGCAGTGGGAAGCGCCGGCCGATCAGGGTGGGAGCCGGCG
CTTGCAGTGGCGCGGGCAGAGGCGATCGGCCCGGGATCGCGCAGCCCTGCAGCCCGCGTGGATC
GAGCTGCCCGGGCGCCCTGAAGGCATTACGACCAGATATGGGCTATAATACTTTAGCCAACTTC
CGAATAGAAAAGAAAATTGGACGTGGACAATTTAGTGAAGTTTATAGAGCATCCTGTCTCCTGG
ATGGAGTTCCAGTAGCTTTAAAAAAAGTGCAGATATTTGATTTAATGGATGCCAAAGCACGTGC
CGATTGTATCAAAGAAATAGATCTCCTTAAGCAACTCAACCATCCAAATGTAATTAAATATTAT
GCATCATTCATTGAAGATAATGAGCTGAACATAGTTTTGGAGTTAGCAGATGCTGGTGACCTCT
CCAGAATGATAAAGCACTTTAAGAAACAAAAGAGGCTAATCCCTGAGAGGACTGTTTGGAAATA
CTTCGTTCAGCTCTGCAGTGCACTGGACCACATGCATTCTCGAAGAGTCATGCACAGAGATATA
AAACCAGCTAATGTGTTCATTACAGCCACTGGGGTAGTCAAACTTGGAGATCTTGGACTTGGTC
GGTTCTTCAGCTCCAAAACCACAGCTGCACATTCTTTAGTGGGCACGCCTTACTACATGTCTCC
AGAGAGGATCCATGAGAACGGATACAACTTCAAGTCTGACATCTGGTCTCTCGGCTGTCTGCTG
TATGAGATGGCGGCGTTGCAGAGTCCTTTCTACGGAGACAAGATGAATCTGTACTCTCTGTGTA
AGAAGATAGAACAGTGTGACTACCCACCTCTCCCATCAGATCACTATTCCGAGGAGCTCCGACA
GTTAGTTAATATATGCATCAACCCAGATCCGGAGAAGCGACCGGACATCGCCTACGTTTATGAT
GTGGCAAAGAGGATGCATGCCTGTACCGCCAGCAGCTAAACTGTACGAGACCCTGAAGACGGCG
ACTTAAATAACTTAAAAGTGTTTTTGTGCAAATCATACCTCCCCGCTTTTGTCTGGGTGTTAAG
ATTACTATTTCAGAGCTAATGCGCTTTGAATCCTTAACCAGTTTTCATATGAGCTTCATTTTCT
ACCAGGCTCAGTCACCTTCCCAACCCCCAACTCTGGGATGCTCAGATTGCATCAAGGACGCAAG
CACAAGAGGTTTTAAGGGCGTAAGGTTTGAGAATTGTTTAGCGTTTCTGCTGAGAGATTGTGTT
TCTAGATAGTAAGTGCCAGGTGGAGGAGGACACAGAGGCACTGTCTGGAGGGAGGAGGCAGAAC
CCGAGGAAAGACCTGAGCATGTGACACGTTTGTTTTTAAGTCACTTAACGGACATCCTAGTGGA
CATAATTGTGAAGTTCTTTGTTTTTTTTTAAGTTTGAAGTACATGTTTTATTTAGTTCTTAGCA
TTATAGTTTTCGAATATAATTCTTATACTAAATGCAGACATGAACTTTTGAGAAAGATTGAAAA
TTTTTAGTTTATACACTCAAAATGCAACTATTAAATGTGAAAACATAGAGGACGAAATGTGAGT
TGGACACTGAAAGTCTCGTGTTTTAATGCCTTTGAAAGCCTTTTTGTGTTTAAATGGTGTGAAT
GAAGCCATTTTAAAAGTGGTTAAGGACTTGTTTGCCTGGCGTGATAGTCATTTTTAAAGTTGCA
CATTGCTCAAGGCTTTGTGTTCTTACTGTACATTTGAAGAATATTCTGGAATAATCTTGTAGTA
ACTATAGTTCAATTTCTTTACAAATCTAAATACACTTAACTCATAGCTATACACTGTAATGTAA
GTGTATATTTTTATTCATATATTGAATGAAGTTTTGATCAGTTCCCCTTCAGAATTTTTTTTTA
TTCAAGTTACTTTCTTATTTATATTGTGTGTGCATTTTATCCACTAAATGTTTCAGATTCTCTG
ACAACGAACTCCCTTTGTAAAAGAGATTTGGTATGCCAACACTTTTCTTAGATTGAAACTTTTT
TTAAAAAACTTTTGGGCCATTCTGTGTGCATCTGTTTTATCTTGTTAGGAAGAGAAGATGTATG
TTAAAATGTGCCTGTGGATGTCGATGTTGTTTGACAGGGTTATAATTTTAGAGTATGTGTAAGG
CCATGGAGACTGGCCCTTAATAGACAGAACCATTAGGAGAGCAGCGTTTCTGTGGAGACACTTT
GGAGTAAAGTACTATATTTGTGTATGAAGATGACAGACATGGGTGATGCTCATTTTAGTTAAGA
AAAAAATATAAAAAGGAGAGCTATTTAGGAAACCCTGAGGTGGAATTTGTTTTCCCTGAATGTC
TTCATCTTAATACCAACCAGTGTCTTGAAAGACTTGTGGAGCCAAAGAACAGAGCGGCCGTGGC
GGTTGCAGAACACTGTGTCCCATGATTGAACATTGGGAAGGCTTATCCTGCTGGTGGGGCAGCT
TGTACTGTGGCCAAAAGAGCTCTTGGGTTTGTTTTCTCACAGAGTATTCTTTCTATAGTTATTG
TCAAGCAATCTGTAAGTTTTCAAAATAGTGGCTCGTCTTTTAATTGGCTGTGCTTGCTGTCTTA
GACAAGGGACATCTGGTTGGTTTTTCATCCTGAAGGCTGAACTGGGTGTGTCCCAGATCTTAGT
GGCTCAGAGCATTTATCCAGAGGCGTGAAGAAAGCTGCTTCTGGCGACCATTTATTTGTATTGT
GCTATGTCCACTCTAATGTCACAGGACTGACCGAGATGCAATATCCCCTGCCTACAAGAGTCAT
TTTCTTTCCATCTTTGAAAACAAAAGGTTCTGCCCGGCATTGGTGGTGCATACTTTTAATCTCA
GCACTTGGAGGGCAGAGGCAGGTGGATCTCTATGAGTTCCAGGACAGCCTGGGCTACACAGAGA
AAAGCCTATCTCAAAAAAACCAAAACCGAATCAATGAAAATACAAGGCTTATCCCTTGTAGTGA
TTTTGCTTTGTGAATCGGTCTTCTAAAAAATGGGGGAGGGGGACTGGGGGGAGCTGGAGACCTT
AATGGTTAGGGATGGTCACTGTCCTTTAGTCCAAGTGTTCATATCCACCCCACCTCCAAAGAAT
CTACTGTGTAACAATAAATTCAGTGTGATATTTGCAAATGGTTATGGAGTTGATTAGAATTTCT
AATCTTAACCATCACCTATAAAATATACTCTTTATATTTCTGTTTATGAGTAATTTGATATGAA
GTTGAATGTTGGAACTGAACTGATTTGAGTAACAGGTCAAATTAAAGGTACGGCTGATTTGAAA
CCTTGCTTGAACATTGGTACTAGTTACCCAGGGGAAAATGGGCAGTAACTGCGGTTGGCACGCT
GAGGTATGGGGTGGTGAATGTAGGGTAGCCTCATCTGCAGTGCTCAAAAAGGTCTAATGATTGT
AGAGCTAGCAAGATGCCGCTGCCAAGTCAAGAGCGCTCTACCGTTCCTAAGTGCGTCCATTACA
AAACACCTGTCTTGTATCCGTAAACTCCAGGTGTTGCTCTTAACCTGTCCTGTATTTATTATAG
CCAAGAAGCTGTTATTCACACAGATTATTCTTTTGAATCGAATGTATTGTTCATCACCCACAAG
TGCACACTCTTTGCCTCTGATCCCCACAGTACTGTAATATGAATTTCTTTTGTGAAATACGTTT
TATTTTGTTATGCTTTAAATGTACATGCAAGAGAACTCTGTTATTAGCTTCAGAAACTGTACAA
TATCGTAATATAAATATATAAAAATAAAAGATGAGTACTGTAAGTTTGA

hide sequence

RefSeq Acc Id:

XM_039090897 ⟹ XP_038946825

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	50,022,212 - 50,149,372 (-)	NCBI

RefSeq Acc Id:

XM_039090898 ⟹ XP_038946826

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	50,022,212 - 50,149,374 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101816	(Get FASTA)	NCBI Sequence Viewer
	XP_006249988	(Get FASTA)	NCBI Sequence Viewer
	XP_038946825	(Get FASTA)	NCBI Sequence Viewer
	XP_038946826	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D3ZBE5	(Get FASTA)	NCBI Sequence Viewer
	EDM09639	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001101816 ⟸ NM_001108346

- UniProtKB:

D3ZBE5 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKK
VQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK
QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTA
AHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYP
PLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTASS

hide sequence

RefSeq Acc Id:	XP_006249988 ⟸ XM_006249926
- Peptide Label:	isoform X3
- UniProtKB:	D3ZBE5 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKK VQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTA AHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYP PLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTASS hide sequence

RefSeq Acc Id:

XP_017454335 ⟸ XM_017598846

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQL
NHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMH
SRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKS
DIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEK
RPDIAYVYDVAKRMHACTASS

hide sequence

RefSeq Acc Id:

ENSRNOP00000069169 ⟸ ENSRNOT00000090162

RefSeq Acc Id:

ENSRNOP00000000817 ⟸ ENSRNOT00000000817

RefSeq Acc Id:	XP_038946826 ⟸ XM_039090898
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038946825 ⟸ XM_039090897
- Peptide Label:	isoform X1

Protein Domains

Protein kinase

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311160	AgrOrtholog
Ensembl Genes	ENSRNOG00000000657	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000000817	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000069169	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000817	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000090162	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:360850	UniProtKB/Swiss-Prot
NCBI Gene	360850	ENTREZGENE
Pfam	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nek7	PhenoGen
PRINTS	TYRKINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JUP0_RAT	UniProtKB/TrEMBL
	D3ZBE5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-11-21	Nek7	NIMA-related kinase 7	Nek7	NIMA (never in mitosis gene a)-related kinase 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-23	Nek7	NIMA (never in mitosis gene a)-related kinase 7	Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	Nek7_predicted	NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Nek7_predicted	NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD