Nek7 (NIMA-related kinase 7) - Rat Genome Database

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Gene: Nek7 (NIMA-related kinase 7) Rattus norvegicus
Analyze
Symbol: Nek7
Name: NIMA-related kinase 7
RGD ID: 1311160
Description: Enables protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to potassium ion; positive regulation of NLRP3 inflammasome complex assembly; and protein phosphorylation. Predicted to act upstream of or within several processes, including cytokine-mediated signaling pathway; positive regulation of defense response; and positive regulation of macromolecule metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in microtubule organizing center and nucleus. Orthologous to human NEK7 (NIMA related kinase 7); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360850; never in mitosis A-related kinase 7; NIMA (never in mitosis gene a)-related expressed kinase 7; NIMA (never in mitosis gene a)-related kinase 7; nimA-related protein kinase 7; serine/threonine-protein kinase Nek7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81352,573,730 - 52,700,869 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1352,573,730 - 52,700,823 (-)EnsemblGRCr8
mRatBN7.21350,022,212 - 50,149,374 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1350,022,218 - 50,149,296 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1352,633,583 - 52,702,078 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01353,921,489 - 53,989,987 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01351,188,092 - 51,257,283 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01355,485,759 - 55,617,534 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,488,531 - 55,561,750 (-)Ensemblrn6Rnor6.0
Rnor_5.01360,515,259 - 60,641,914 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41351,679,191 - 51,942,636 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1350,308,775 - 50,377,141 (-)NCBICelera
RGSC_v3.11351,696,338 - 51,802,947 (-)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA)
cytoplasm  (IEA,ISO,ISS)
cytoskeleton  (IEA)
microtubule organizing center  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)
spindle pole  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase. Belham C, etal., Curr Biol. 2001 Aug 7;11(15):1155-67.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12840024   PMID:21531765   PMID:26188091   PMID:31505169   PMID:34414459  


Genomics

Comparative Map Data
Nek7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81352,573,730 - 52,700,869 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1352,573,730 - 52,700,823 (-)EnsemblGRCr8
mRatBN7.21350,022,212 - 50,149,374 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1350,022,218 - 50,149,296 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1352,633,583 - 52,702,078 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01353,921,489 - 53,989,987 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01351,188,092 - 51,257,283 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01355,485,759 - 55,617,534 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,488,531 - 55,561,750 (-)Ensemblrn6Rnor6.0
Rnor_5.01360,515,259 - 60,641,914 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41351,679,191 - 51,942,636 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1350,308,775 - 50,377,141 (-)NCBICelera
RGSC_v3.11351,696,338 - 51,802,947 (-)NCBI
Cytogenetic Map13q13NCBI
NEK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381198,156,998 - 198,322,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1198,156,994 - 198,322,420 (+)Ensemblhg38GRCh38
GRCh371198,126,128 - 198,291,550 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361196,468,306 - 196,555,392 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341194,933,338 - 195,020,426NCBI
Celera1171,248,701 - 171,414,114 (+)NCBICelera
Cytogenetic Map1q31.3NCBI
HuRef1169,281,535 - 169,446,709 (+)NCBIHuRef
CHM1_11199,548,440 - 199,713,855 (+)NCBICHM1_1
T2T-CHM13v2.01197,416,379 - 197,581,805 (+)NCBIT2T-CHM13v2.0
Nek7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391138,411,575 - 138,547,481 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1138,410,613 - 138,547,879 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381138,483,837 - 138,619,757 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1138,482,875 - 138,620,141 (-)Ensemblmm10GRCm38
MGSCv371140,381,291 - 140,516,273 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361140,301,125 - 140,436,107 (-)NCBIMGSCv36mm8
Celera1141,116,690 - 141,252,989 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.82NCBI
Nek7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540634,626,494 - 34,717,546 (+)Ensembl
ChiLan1.0NW_00495540634,575,292 - 34,714,024 (+)NCBIChiLan1.0ChiLan1.0
NEK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2151,064,827 - 51,230,182 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1151,024,328 - 51,189,816 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01173,752,892 - 173,918,258 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11178,063,721 - 178,228,197 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1178,138,925 - 178,228,197 (+)EnsemblpanPan2panpan1.1
NEK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.174,557,754 - 4,755,912 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl74,555,231 - 4,704,955 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha74,242,787 - 4,401,020 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.074,244,695 - 4,403,399 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl74,244,697 - 4,401,233 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.174,191,041 - 4,349,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.074,291,900 - 4,450,309 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.074,323,524 - 4,481,976 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nek7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934476,450,900 - 76,580,386 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365675,685,125 - 5,808,499 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365675,685,619 - 5,815,094 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1020,966,651 - 21,124,271 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11020,966,660 - 21,124,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21025,627,135 - 25,785,075 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12531,111,332 - 31,257,445 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2531,110,616 - 31,257,374 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605532,000,563 - 32,147,161 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nek7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247982,116,900 - 2,198,999 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247982,116,888 - 2,283,061 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Nek7
1336 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:99
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000000817
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
BF386197  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21350,038,614 - 50,038,770 (+)MAPPERmRatBN7.2
Rnor_6.01355,502,217 - 55,502,372NCBIRnor6.0
Rnor_5.01360,531,717 - 60,531,872UniSTSRnor5.0
RGSC_v3.41351,696,144 - 51,696,299UniSTSRGSC3.4
Celera1350,322,354 - 50,322,509UniSTS
Cytogenetic Map13q13UniSTS
RH136376  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81352,575,592 - 52,575,858 (+)Marker Load Pipeline
mRatBN7.21350,024,073 - 50,024,340 (+)MAPPERmRatBN7.2
Rnor_6.01355,487,621 - 55,487,887NCBIRnor6.0
Rnor_5.01360,517,121 - 60,517,387UniSTSRnor5.0
RGSC_v3.41351,681,295 - 51,681,561UniSTSRGSC3.4
Celera1350,307,811 - 50,308,077UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000000817   ⟹   ENSRNOP00000000817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1352,573,730 - 52,700,823 (-)Ensembl
mRatBN7.2 Ensembl1350,022,218 - 50,149,296 (-)Ensembl
Rnor_6.0 Ensembl1355,488,585 - 55,561,726 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090162   ⟹   ENSRNOP00000069169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1352,573,730 - 52,700,823 (-)Ensembl
mRatBN7.2 Ensembl1350,022,218 - 50,149,296 (-)Ensembl
Rnor_6.0 Ensembl1355,488,531 - 55,561,750 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095155   ⟹   ENSRNOP00000086821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1350,022,232 - 50,093,474 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098011   ⟹   ENSRNOP00000093817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1352,573,730 - 52,630,115 (-)Ensembl
mRatBN7.2 Ensembl1350,022,218 - 50,078,602 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000163858   ⟹   ENSRNOP00000106955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1352,575,649 - 52,700,823 (-)Ensembl
RefSeq Acc Id: NM_001108346   ⟹   NP_001101816
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,573,730 - 52,700,823 (-)NCBI
mRatBN7.21350,022,212 - 50,149,321 (-)NCBI
Rnor_6.01355,488,585 - 55,561,726 (-)NCBI
Rnor_5.01360,515,259 - 60,641,914 (-)NCBI
RGSC_v3.41351,679,191 - 51,942,636 (-)RGD
Celera1350,308,775 - 50,377,141 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272469   ⟹   XP_063128539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,573,736 - 52,663,412 (-)NCBI
RefSeq Acc Id: XM_063272470   ⟹   XP_063128540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,573,736 - 52,700,869 (-)NCBI
RefSeq Acc Id: XM_063272471   ⟹   XP_063128541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,573,736 - 52,627,724 (-)NCBI
RefSeq Acc Id: NP_001101816   ⟸   NM_001108346
- UniProtKB: D3ZBE5 (UniProtKB/Swiss-Prot),   A0A0G2JUP0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069169   ⟸   ENSRNOT00000090162
Ensembl Acc Id: ENSRNOP00000000817   ⟸   ENSRNOT00000000817
Ensembl Acc Id: ENSRNOP00000093817   ⟸   ENSRNOT00000098011
Ensembl Acc Id: ENSRNOP00000086821   ⟸   ENSRNOT00000095155
RefSeq Acc Id: XP_063128540   ⟸   XM_063272470
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AKB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128539   ⟸   XM_063272469
- Peptide Label: isoform X1
- UniProtKB: D3ZBE5 (UniProtKB/Swiss-Prot),   A0A0G2JUP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128541   ⟸   XM_063272471
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AKB8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106955   ⟸   ENSRNOT00000163858
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBE5-F1-model_v2 AlphaFold D3ZBE5 1-302 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311160 AgrOrtholog
BioCyc Gene G2FUF-18102 BioCyc
Ensembl Genes ENSRNOG00000000657 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000817 ENTREZGENE
  ENSRNOT00000000817.7 UniProtKB/Swiss-Prot
  ENSRNOT00000098011 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:360850 UniProtKB/Swiss-Prot
NCBI Gene 360850 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE NEK7 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Nek7 PhenoGen
PIRSF Integrin-linked_kinase UniProtKB/Swiss-Prot
PRINTS TYRKINASE UniProtKB/Swiss-Prot
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000000657 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A0G2JUP0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A625_RAT UniProtKB/TrEMBL
  A0A8I6AKB8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBE5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-21 Nek7  NIMA-related kinase 7  Nek7  NIMA (never in mitosis gene a)-related kinase 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Nek7  NIMA (never in mitosis gene a)-related kinase 7  Nek7  NIMA (never in mitosis gene a)-related expressed kinase 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Nek7  NIMA (never in mitosis gene a)-related expressed kinase 7  Nek7_predicted  NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Nek7_predicted  NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED