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Gene: Rgs2 (regulator of G-protein signaling 2) Rattus norvegicus
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Symbol: Rgs2
Name: regulator of G-protein signaling 2
Description: Exhibits beta-tubulin binding activity. Involved in several processes, including negative regulation of glycine import across plasma membrane; ovulation; and regulation of cell development. Localizes to the cytoplasm; cytoplasmic side of plasma membrane; and neuron projection. Biomarker of bladder disease (multiple); glomerulosclerosis; hypertension; liver cirrhosis; and opioid abuse. Orthologous to human RGS2 (regulator of G protein signaling 2); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: regulator of G-protein signaling protein 2
Orthologs:
Homo sapiens (human) : RGS2 (regulator of G protein signaling 2)  HGNC  Alliance
Mus musculus (house mouse) : Rgs2 (regulator of G-protein signaling 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs2 (regulator of G protein signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS2 (regulator of G protein signaling 2)
Canis lupus familiaris (dog) : RGS2 (regulator of G protein signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs2 (regulator of G protein signaling 2)
Sus scrofa (pig) : RGS2 (regulator of G protein signaling 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01360,846,458 - 60,849,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,846,308 - 60,849,094 (-)Ensembl
Rnor_5.01365,831,386 - 65,833,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,891,849 - 57,894,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,905,025 - 57,908,545 (-)NCBI
Celera1355,875,644 - 55,878,228 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Rgs2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621665
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.