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Gene: Rgs2 (regulator of G-protein signaling 2) Rattus norvegicus
Symbol: Rgs2
Name: regulator of G-protein signaling 2
RGD ID: 621665
Description: Exhibits beta-tubulin binding activity. Involved in several processes, including negative regulation of glycine import across plasma membrane; ovulation; and regulation of cell development. Localizes to cytoplasm; cytoplasmic side of plasma membrane; and neuron projection. Biomarker of bladder disease (multiple); glomerulosclerosis; hypertension; liver cirrhosis; and opioid abuse. Orthologous to human RGS2 (regulator of G protein signaling 2); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: regulator of G-protein signaling protein 2
Homo sapiens (human) : RGS2 (regulator of G protein signaling 2)  HGNC  Alliance
Mus musculus (house mouse) : Rgs2 (regulator of G-protein signaling 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs2 (regulator of G protein signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS2 (regulator of G protein signaling 2)
Canis lupus familiaris (dog) : RGS2 (regulator of G protein signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs2 (regulator of G protein signaling 2)
Sus scrofa (pig) : RGS2 (regulator of G protein signaling 2)
Chlorocebus sabaeus (African green monkey) : RGS2 (regulator of G protein signaling 2)
Heterocephalus glaber (naked mole-rat) : Rgs2 (regulator of G protein signaling 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01360,846,458 - 60,849,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,846,308 - 60,849,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,831,386 - 65,833,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,891,849 - 57,894,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,905,025 - 57,908,545 (-)NCBI
Celera1355,875,644 - 55,878,228 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Rgs2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621665
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.