RGS2 (regulator of G protein signaling 2) - Rat Genome Database
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Gene: RGS2 (regulator of G protein signaling 2) Pan paniscus
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Symbol: RGS2
Name: regulator of G protein signaling 2
RGD ID: 11932695
Description: ENCODES a protein that exhibits beta-tubulin binding (ortholog); G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); INVOLVED IN brain development (ortholog); brown fat cell differentiation (ortholog); maternal process involved in female pregnancy (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; ASSOCIATED WITH acute myeloid leukemia (ortholog); bladder disease (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11172,566,701 - 172,569,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,566,701 - 172,569,955 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01168,273,112 - 168,276,348 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
RGS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11172,566,701 - 172,569,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,566,701 - 172,569,955 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01168,273,112 - 168,276,348 (+)NCBIMhudiblu_PPA_v0panPan3
RGS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1192,809,039 - 192,812,275 (+)EnsemblGRCh38hg38GRCh38
GRCh381192,809,039 - 192,812,275 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371192,778,169 - 192,781,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,044,794 - 191,048,026 (+)NCBINCBI36hg18NCBI36
Build 341189,509,827 - 189,513,060NCBI
Celera1165,887,766 - 165,891,002 (+)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,013,977 - 164,017,213 (+)NCBIHuRef
CHM1_11194,199,847 - 194,203,081 (+)NCBICHM1_1
Rgs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,875,076 - 143,879,887 (-)NCBIGRCm39mm39
GRCm381143,999,338 - 144,004,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,999,338 - 144,004,161 (-)EnsemblGRCm38mm10GRCm38
MGSCv371145,846,468 - 145,851,279 (-)NCBIGRCm37mm9NCBIm37
MGSCv361145,762,215 - 145,766,367 (-)NCBImm8
Celera1146,559,706 - 146,564,519 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.56NCBI
Rgs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01360,846,458 - 60,849,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,846,308 - 60,849,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,831,386 - 65,833,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,891,849 - 57,894,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,905,025 - 57,908,545 (-)NCBI
Celera1355,875,644 - 55,878,228 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,261,757 - 30,266,005 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,261,757 - 30,265,389 (+)NCBIChiLan1.0ChiLan1.0
RGS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl386,200,657 - 6,203,494 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1386,200,237 - 6,203,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rgs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366381,065,866 - 1,068,649 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl10936,789 - 940,098 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.110936,836 - 940,083 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,543,481 - 2,546,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap10pNCBI
RGS2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,620,047 - 36,623,367 (-)NCBI
ChlSab1.1 Ensembl2536,619,140 - 36,623,308 (-)Ensembl
Rgs2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624814754,743 - 758,148 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003820595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000048251   ⟹   ENSPPAP00000025424
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,566,701 - 172,569,955 (+)Ensembl
RefSeq Acc Id: XM_003820595   ⟹   XP_003820643
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11172,566,701 - 172,569,955 (+)NCBI
Mhudiblu_PPA_v01168,273,112 - 168,276,348 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820643 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003820643   ⟸   XM_003820595
- Sequence:
RefSeq Acc Id: ENSPPAP00000025424   ⟸   ENSPPAT00000048251
Protein Domains
RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035845 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000025424 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048251 UniProtKB/TrEMBL
Gene3D-CATH 1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS2 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
KEGG Report pps:100995309 UniProtKB/TrEMBL
NCBI Gene RGS2 ENTREZGENE
PANTHER PTHR10845:SF43 UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A2R9BEH1_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-07 RGS2  regulator of G protein signaling 2    regulator of G-protein signaling 2  Symbol and/or name change 5135510 APPROVED