Rgs2 (regulator of G protein signaling 2) - Rat Genome Database

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Gene: Rgs2 (regulator of G protein signaling 2) Heterocephalus glaber
Analyze
Symbol: Rgs2
Name: regulator of G protein signaling 2
RGD ID: 18901817
Description: ENCODES a protein that exhibits beta-tubulin binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); maternal process involved in female pregnancy (ortholog); negative regulation of cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; ASSOCIATED WITH acute myeloid leukemia (ortholog); bladder disease (ortholog); Breast Neoplasms (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624814753,164 - 758,192 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624814754,743 - 758,148 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Rgs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624814753,164 - 758,192 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624814754,743 - 758,148 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RGS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,809,039 - 192,812,275 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,809,039 - 192,812,275 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,778,169 - 192,781,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,044,794 - 191,048,026 (+)NCBINCBI36Build 36hg18NCBI36
Build 341189,509,827 - 189,513,060NCBI
Celera1165,887,766 - 165,891,002 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1164,013,977 - 164,017,213 (+)NCBIHuRef
CHM1_11194,199,847 - 194,203,081 (+)NCBICHM1_1
T2T-CHM13v2.01192,156,109 - 192,159,345 (+)NCBIT2T-CHM13v2.0
Rgs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,875,076 - 143,879,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1143,875,076 - 143,879,899 (-)EnsemblGRCm39 Ensembl
GRCm381143,999,338 - 144,004,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,999,338 - 144,004,161 (-)EnsemblGRCm38mm10GRCm38
MGSCv371145,846,468 - 145,851,279 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361145,762,215 - 145,766,367 (-)NCBIMGSCv36mm8
Celera1146,559,706 - 146,564,519 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.56NCBI
Rgs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81358,350,063 - 58,352,666 (-)NCBIGRCr8
mRatBN7.21355,799,749 - 55,802,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1355,798,829 - 55,802,385 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1358,360,545 - 58,363,155 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01359,628,437 - 59,631,073 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01356,918,817 - 56,921,454 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01360,846,458 - 60,849,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,846,308 - 60,849,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,831,386 - 65,833,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,891,849 - 57,894,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11357,905,025 - 57,908,545 (-)NCBI
Celera1355,875,644 - 55,878,228 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,261,757 - 30,266,005 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,261,757 - 30,265,389 (+)NCBIChiLan1.0ChiLan1.0
RGS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2156,975,986 - 56,983,152 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,639,690 - 56,643,525 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,273,112 - 168,276,348 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,566,701 - 172,569,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,566,701 - 172,569,955 (+)Ensemblpanpan1.1panPan2
RGS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1386,200,237 - 6,203,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl386,200,657 - 6,203,494 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,297,498 - 6,300,827 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0386,217,614 - 6,220,944 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl386,217,616 - 6,220,924 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1386,216,415 - 6,219,748 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0386,582,061 - 6,585,388 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0386,817,823 - 6,821,151 (-)NCBIUU_Cfam_GSD_1.0
Rgs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934481,075,734 - 81,079,076 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366381,065,832 - 1,069,247 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366381,065,866 - 1,068,649 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl10936,789 - 940,098 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.110936,836 - 940,083 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,543,481 - 2,546,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap10pNCBI
RGS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,620,047 - 36,623,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,619,140 - 36,623,308 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,569,789 - 37,573,061 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005684   ⟹   ENSHGLP00000005612
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624814753,164 - 758,192 (-)Ensembl
RefSeq Acc Id: XM_004862770   ⟹   XP_004862827
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624814754,743 - 758,148 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004862827 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99977 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005612
  ENSHGLP00000047153
  ENSHGLP00100038006
GenBank Protein JAO01692 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004862827   ⟸   XM_004862770
- UniProtKB: G5ASG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000005612   ⟸   ENSHGLT00000005684


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004101 Ensembl, ENTREZGENE
  ENSHGLG00000042820 UniProtKB/TrEMBL
  ENSHGLG00100050416 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000005684 ENTREZGENE
  ENSHGLT00000050061 UniProtKB/TrEMBL
  ENSHGLT00100065536 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS2 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
KEGG Report hgl:101699901 UniProtKB/TrEMBL
NCBI Gene Rgs2 ENTREZGENE
PANTHER PTHR10845:SF43 UniProtKB/TrEMBL
  REGULATOR OF G PROTEIN SIGNALING UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt G5ASG7 ENTREZGENE, UniProtKB/TrEMBL