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Gene: Tubb5 (tubulin, beta 5 class I) Rattus norvegicus
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Symbol: Tubb5
Name: tubulin, beta 5 class I
Description: Exhibits GTPase activating protein binding activity and protein domain specific binding activity. Predicted to be involved in mitotic cell cycle; regulation of synapse organization; and spindle assembly. Localizes to the membrane raft and protein-containing complex. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6. Orthologous to human TUBB (tubulin beta class I); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH (S)-colchicine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Tubb; tubulin beta-5 chain; tubulin, beta; tubulin, beta 5
Orthologs:
Homo sapiens (human) : TUBB (tubulin beta class I)  HGNC  Alliance
Mus musculus (house mouse) : Tubb5 (tubulin, beta 5 class I)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tubb (tubulin beta class I)
Pan paniscus (bonobo/pygmy chimpanzee) : TUBB (tubulin beta class I)
Canis lupus familiaris (dog) : TUBB (tubulin beta class I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tubb (tubulin beta class I)
Sus scrofa (pig) : TUBB (tubulin beta class I)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,422,448 - 3,426,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,422,461 - 3,426,371 (+)Ensembl
Rnor_5.0205,519,551 - 5,523,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,060,224 - 3,090,776 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,060,491 - 3,065,012 (+)NCBI
Celera20338,700 - 342,843 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tubb5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628596
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.