Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rgs2 (regulator of G-protein signaling 2) Mus musculus
Symbol: Rgs2
Name: regulator of G-protein signaling 2
Description: Predicted to have G-protein alpha-subunit binding activity; GTPase activator activity; and beta-tubulin binding activity. Involved in several processes, including brown fat cell differentiation; negative regulation of signal transduction; and regulation of muscle system process. Localizes to cytoplasmic side of plasma membrane and cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and immune system. Orthologous to human RGS2 (regulator of G protein signaling 2); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GOS8
Homo sapiens (human) : RGS2 (regulator of G protein signaling 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rgs2 (regulator of G-protein signaling 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs2 (regulator of G protein signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS2 (regulator of G protein signaling 2)
Canis lupus familiaris (dog) : RGS2 (regulator of G protein signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs2 (regulator of G protein signaling 2)
Sus scrofa (pig) : RGS2 (regulator of G protein signaling 2)
Chlorocebus sabaeus (African green monkey) : RGS2 (regulator of G protein signaling 2)
Heterocephalus glaber (naked mole-rat) : Rgs2 (regulator of G protein signaling 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1143,999,338 - 144,004,161 (-)EnsemblGRCm38mm10GRCm38
GRCm381143,999,338 - 144,004,149 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371145,846,468 - 145,851,279 (-)NCBIGRCm37mm9NCBIm37
MGSCv361145,762,215 - 145,766,367 (-)NCBImm8
Celera1146,559,706 - 146,564,519 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rgs2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732361
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.