Gene: Adamts4 (ADAM metallopeptidase with thrombospondin type 1 motif, 4) Rattus norvegicus
Symbol: Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Description: ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); metallopeptidase activity (ortholog); protease binding (ortholog); INVOLVED IN tooth eruption; defense response to bacterium (ortholog); proteolysis (ortholog); ASSOCIATED WITH Intervertebral Disc Degeneration; transient cerebral ischemia; Arthritis, Rheumatoid (ortholog); FOUND IN extracellular space (ortholog); nuclear speck (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a disintegrin and metallopeptidase with thrombospondin motifs 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; Aggrecanase; aggrecanase-1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01389,622,996 - 89,632,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,249,862 - 94,259,351 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,142,442 - 87,151,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,336,962 - 87,339,836 (+)NCBI
Celera1383,301,254 - 83,310,782 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adamts4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621242
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-04-17
Status: ACTIVE