Gene: Adamts4 (ADAM metallopeptidase with thrombospondin type 1 motif, 4) Rattus norvegicus
Symbol: Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Description: ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); metallopeptidase activity (ortholog); protease binding (ortholog); INVOLVED IN tooth eruption; defense response to bacterium (ortholog); proteolysis (ortholog); ASSOCIATED WITH degenerative disc disease; transient cerebral ischemia; mitochondrial complex I deficiency (ortholog); FOUND IN extracellular space (ortholog); nuclear speck (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a disintegrin and metallopeptidase with thrombospondin motifs 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; Aggrecanase; aggrecanase-1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01389,622,996 - 89,632,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,249,862 - 94,259,351 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,142,442 - 87,151,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,336,962 - 87,339,836 (+)NCBI
Celera1383,301,254 - 83,310,782 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adamts4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621242
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-05-29
Status: ACTIVE