Gene: Adamts4 (ADAM metallopeptidase with thrombospondin type 1 motif, 4) Rattus norvegicus
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Symbol: Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Description: ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); metallopeptidase activity (ortholog); protease binding (ortholog); INVOLVED IN tooth eruption; defense response to bacterium (ortholog); proteolysis (ortholog); ASSOCIATED WITH Intervertebral Disc Degeneration; transient cerebral ischemia; Arthritis, Rheumatoid (ortholog); FOUND IN extracellular space (ortholog); nuclear speck (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a disintegrin and metallopeptidase with thrombospondin motifs 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; Aggrecanase; aggrecanase-1
Orthologs:
Homo sapiens (human) : ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)  HGNC  Alliance
Mus musculus (house mouse) : Adamts4 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adamts4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)
Canis lupus familiaris (dog) : ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adamts4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01389,622,996 - 89,632,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,249,862 - 94,259,351 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,142,442 - 87,151,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,336,962 - 87,339,836 (+)NCBI
Celera1383,301,254 - 83,310,782 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Adamts4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621242
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-04-17
Status: ACTIVE



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