17beta-estradiol increases expression ISO RGD:1346398 6480464 Estradiol results in increased expression of ADAMTS4 mRNA CTD PMID:25321415 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS4 mRNA CTD PMID:32741896 17beta-estradiol decreases expression ISO RGD:1550099 6480464 Estradiol results in decreased expression of ADAMTS4 mRNA CTD PMID:19484750 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS4 mRNA CTD PMID:32741896 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1550099 6480464 Tetrachlorodibenzodioxin affects the expression of ADAMTS4 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ADAMTS4 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1550099 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADAMTS4 mRNA CTD PMID:33956508 2,4-diaminotoluene increases expression ISO RGD:1550099 6480464 2, 4-diaminotoluene results in increased expression of ADAMTS4 mRNA CTD PMID:20713471 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 2-butoxyethanol increases expression ISO RGD:1550099 6480464 n-butoxyethanol results in increased expression of ADAMTS4 mRNA CTD PMID:19812364 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1550099 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of ADAMTS4 mRNA CTD PMID:20188158 3-methylcholanthrene increases expression ISO RGD:1550099 6480464 Methylcholanthrene results in increased expression of ADAMTS4 mRNA CTD PMID:20713471 4,4'-sulfonyldiphenol increases methylation ISO RGD:1550099 6480464 bis(4-hydroxyphenyl)sulfone results in increased methylation of ADAMTS4 exon, bis(4-hydroxyphenyl)sulfone results in increased methylation of ADAMTS4 promoter CTD PMID:33297965 4,4'-sulfonyldiphenol decreases methylation ISO RGD:1346398 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of ADAMTS4 gene CTD PMID:31601247 4-hydroxyphenyl retinamide increases expression ISO RGD:1550099 6480464 Fenretinide results in increased expression of ADAMTS4 mRNA CTD PMID:28973697 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of ADAMTS4 mRNA CTD PMID:24780913 , PMID:25825206 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 all-trans-retinoic acid multiple interactions ISO RGD:1346398 6480464 [Tretinoin co-treated with arsenic trioxide] results in decreased expression of ADAMTS4 mRNA CTD PMID:15894607 all-trans-retinoic acid decreases expression ISO RGD:1346398 6480464 Tretinoin results in decreased expression of ADAMTS4 mRNA CTD PMID:23724009 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ADAMTS4 mRNA CTD PMID:16483693 arsenite(3-) decreases expression ISO RGD:1550099 6480464 arsenite results in decreased expression of ADAMTS4 mRNA CTD PMID:18929588 arsenite(3-) multiple interactions ISO RGD:1550099 6480464 TRP53 protein affects the reaction [arsenite results in decreased expression of ADAMTS4 mRNA] CTD PMID:18929588 arsenous acid multiple interactions ISO RGD:1346398 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ADAMTS4 mRNA CTD PMID:15894607 benzo[a]pyrene increases mutagenesis ISO RGD:1346398 6480464 Benzo(a)pyrene results in increased mutagenesis of ADAMTS4 gene CTD PMID:25435355 benzo[a]pyrene increases methylation ISO RGD:1346398 6480464 Benzo(a)pyrene results in increased methylation of ADAMTS4 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:1550099 6480464 Benzo(a)pyrene results in decreased expression of ADAMTS4 mRNA CTD PMID:27195522 benzo[b]fluoranthene increases expression ISO RGD:1550099 6480464 benzo(b)fluoranthene results in increased expression of ADAMTS4 mRNA CTD PMID:26377693 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1346398 6480464 Diethylhexyl Phthalate results in decreased expression of ADAMTS4 mRNA CTD PMID:31163220 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ADAMTS4 mRNA CTD PMID:25181051 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ADAMTS4 mRNA CTD PMID:34947998 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of ADAMTS4 gene CTD PMID:28505145 bisphenol A increases expression ISO RGD:1346398 6480464 bisphenol A results in increased expression of ADAMTS4 mRNA CTD PMID:27685785 carbon nanotube increases expression ISO RGD:1550099 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carmustine decreases expression ISO RGD:1346398 6480464 Carmustine results in decreased expression of ADAMTS4 mRNA CTD PMID:15980968 CGP 52608 multiple interactions ISO RGD:1346398 6480464 CGP 52608 promotes the reaction [RORA protein binds to ADAMTS4 gene] CTD PMID:28238834 cisplatin multiple interactions ISO RGD:1346398 6480464 [Cisplatin co-treated with Paclitaxel] affects the expression of ADAMTS4 mRNA CTD PMID:20705681 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of ADAMTS4 mRNA CTD PMID:24386269 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of ADAMTS4 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of ADAMTS4 mRNA CTD PMID:26033743 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of ADAMTS4 mRNA CTD PMID:26577399 , PMID:27523638 curcumin increases expression ISO RGD:1346398 6480464 Curcumin results in increased expression of ADAMTS4 mRNA CTD PMID:18321735 dexamethasone decreases expression ISO RGD:1550099 6480464 Dexamethasone results in decreased expression of ADAMTS4 mRNA CTD PMID:22733784 dextran sulfate multiple interactions ISO RGD:1550099 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS4 mRNA CTD PMID:29950665 diarsenic trioxide multiple interactions ISO RGD:1346398 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ADAMTS4 mRNA CTD PMID:15894607 dimethylarsinic acid multiple interactions ISO RGD:1550099 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of ADAMTS4 mRNA CTD PMID:34876320 dioxygen multiple interactions ISO RGD:1550099 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ADAMTS4 mRNA CTD PMID:30529165 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of ADAMTS4 mRNA CTD PMID:33729688 dopamine increases expression EXP 6480464 Dopamine results in increased expression of ADAMTS4 mRNA CTD PMID:21983523 doxorubicin decreases expression ISO RGD:1346398 6480464 Doxorubicin results in decreased expression of ADAMTS4 mRNA CTD PMID:29803840 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ADAMTS4 mRNA CTD PMID:29391264 ethanol multiple interactions ISO RGD:1550099 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ADAMTS4 mRNA CTD PMID:30517762 ethanol increases expression ISO RGD:1550099 6480464 Ethanol results in increased expression of ADAMTS4 mRNA CTD PMID:30319688 fenoldopam decreases expression EXP 6480464 Fenoldopam results in decreased expression of ADAMTS4 mRNA CTD PMID:21983523 fluoranthene multiple interactions ISO RGD:1550099 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ADAMTS4 mRNA CTD PMID:28329830 genistein decreases expression ISO RGD:1550099 6480464 Genistein results in decreased expression of ADAMTS4 mRNA CTD PMID:32186404 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ADAMTS4 mRNA CTD PMID:33387578 graphene oxide increases expression ISO RGD:1550099 6480464 graphene oxide results in increased expression of ADAMTS4 mRNA CTD PMID:33227293 L-proline betaine multiple interactions ISO RGD:1346398 6480464 stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein] CTD PMID:32417162 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of ADAMTS4 mRNA CTD PMID:22641619 methylarsonic acid multiple interactions ISO RGD:1550099 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of ADAMTS4 mRNA CTD PMID:34876320 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of ADAMTS4 mRNA CTD PMID:31378766 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:1550099 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of ADAMTS4 mRNA CTD PMID:22401849 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ADAMTS4 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:1550099 6480464 [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ADAMTS4 mRNA CTD PMID:25658374 ozone increases expression ISO RGD:1550099 6480464 Ozone results in increased expression of ADAMTS4 mRNA CTD PMID:17460151 more ... paclitaxel multiple interactions ISO RGD:1346398 6480464 [Cisplatin co-treated with Paclitaxel] affects the expression of ADAMTS4 mRNA CTD PMID:20705681 paracetamol affects expression ISO RGD:1550099 6480464 Acetaminophen affects the expression of ADAMTS4 mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ADAMTS4 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1550099 6480464 Acetaminophen results in increased expression of ADAMTS4 mRNA CTD PMID:34724096 paracetamol increases expression ISO RGD:1346398 6480464 Acetaminophen results in increased expression of ADAMTS4 mRNA CTD PMID:22230336 propanal increases expression ISO RGD:1346398 6480464 propionaldehyde results in increased expression of ADAMTS4 mRNA CTD PMID:26079696 resveratrol multiple interactions ISO RGD:1346398 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of ADAMTS4 mRNA CTD PMID:23557933 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of ADAMTS4 mRNA CTD PMID:28374803 silicon dioxide increases expression ISO RGD:1550099 6480464 Silicon Dioxide results in increased expression of ADAMTS4 mRNA CTD PMID:23221170 , PMID:29341224 sodium arsenate multiple interactions ISO RGD:1550099 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of ADAMTS4 mRNA CTD PMID:34876320 sodium arsenite multiple interactions ISO RGD:1550099 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of ADAMTS4 mRNA CTD PMID:34876320 T-2 toxin increases expression ISO RGD:1550099 6480464 T-2 Toxin results in increased expression of ADAMTS4 mRNA CTD PMID:22800716 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS4 mRNA CTD PMID:32741896 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of ADAMTS4 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions ISO RGD:1550099 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ADAMTS4 mRNA CTD PMID:30517762 thapsigargin decreases expression ISO RGD:1346398 6480464 Thapsigargin results in decreased expression of ADAMTS4 mRNA CTD PMID:22378314 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ADAMTS4 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO RGD:1550099 6480464 titanium dioxide results in decreased expression of ADAMTS4 mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO RGD:1550099 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS4 mRNA CTD PMID:29950665 titanium dioxide increases expression ISO RGD:1550099 6480464 titanium dioxide results in increased expression of ADAMTS4 mRNA CTD PMID:27760801 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ADAMTS4 mRNA CTD PMID:25729387 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of ADAMTS4 mRNA CTD PMID:33387578 triclosan increases expression ISO RGD:1346398 6480464 Triclosan results in increased expression of ADAMTS4 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:1550099 6480464 trimellitic anhydride results in increased expression of ADAMTS4 mRNA CTD PMID:19042947 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1346398 6480464 tris(2-butoxyethyl) phosphate affects the expression of ADAMTS4 mRNA CTD PMID:29024780 urethane increases expression ISO RGD:1346398 6480464 Urethane results in increased expression of ADAMTS4 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:1346398 6480464 Valproic Acid results in increased methylation of ADAMTS4 gene CTD PMID:29154799 vanadium atom decreases expression ISO RGD:1346398 6480464 Vanadium results in decreased expression of ADAMTS4 mRNA CTD PMID:19000753 vanadium(0) decreases expression ISO RGD:1346398 6480464 Vanadium results in decreased expression of ADAMTS4 mRNA CTD PMID:19000753 WIN 55212-2 decreases activity ISO RGD:1346398 6480464 (3R)-((2 more ... CTD PMID:27082728 WIN 55212-2 multiple interactions ISO RGD:1346398 6480464 (3R)-((2 more ... CTD PMID:27082728 yohimbine increases expression EXP 6480464 Yohimbine results in increased expression of ADAMTS4 mRNA CTD PMID:21983523
