Sec16b (SEC16 homolog B, endoplasmic reticulum export factor) - Rat Genome Database

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Gene: Sec16b (SEC16 homolog B, endoplasmic reticulum export factor) Rattus norvegicus
Analyze
Symbol: Sec16b
Name: SEC16 homolog B, endoplasmic reticulum export factor
RGD ID: 621658
Description: Predicted to be involved in several processes, including peroxisome fission; positive regulation of protein exit from endoplasmic reticulum; and protein localization to endoplasmic reticulum exit site. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in ER to Golgi transport vesicle membrane and endoplasmic reticulum exit site. Orthologous to several human genes including SEC16B (SEC16 homolog B, endoplasmic reticulum export factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine zipper transcription regulator 2; Lztr2; protein transport protein Sec16B; regucalcin gene promoter region related protein; regucalcin gene promoter region-related protein p117; RGPR; RGPR-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81372,206,778 - 72,260,733 (+)NCBIGRCr8
mRatBN7.21369,665,757 - 69,727,199 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1369,684,291 - 69,727,196 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1372,251,310 - 72,293,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01373,566,357 - 73,609,814 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01370,827,850 - 70,871,307 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01375,153,074 - 75,216,941 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,175,254 - 75,216,941 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,090,341 - 80,133,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,787,822 - 72,830,908 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11372,802,009 - 72,845,095 (+)NCBI
Celera1369,513,230 - 69,555,087 (+)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. Misawa H and Yamaguchi M, Int J Mol Med 2001 Nov;8(5):513-20.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Novel protein RGPR-p117: the gene expression in physiologic state and the binding activity to regucalcin gene promoter region in rat liver. Yamaguchi M, etal., J Cell Biochem 2003 Apr 15;88(6):1092-100.
Additional References at PubMed
PMID:16211248   PMID:16273285   PMID:16676356   PMID:17549392   PMID:17786289   PMID:21478858   PMID:21768384   PMID:22355596   PMID:35835253  


Genomics

Comparative Map Data
Sec16b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81372,206,778 - 72,260,733 (+)NCBIGRCr8
mRatBN7.21369,665,757 - 69,727,199 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1369,684,291 - 69,727,196 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1372,251,310 - 72,293,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01373,566,357 - 73,609,814 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01370,827,850 - 70,871,307 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01375,153,074 - 75,216,941 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,175,254 - 75,216,941 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,090,341 - 80,133,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,787,822 - 72,830,908 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11372,802,009 - 72,845,095 (+)NCBI
Celera1369,513,230 - 69,555,087 (+)NCBICelera
Cytogenetic Map13q22NCBI
SEC16B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381177,928,788 - 177,984,284 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1177,923,956 - 177,984,303 (-)EnsemblGRCh38hg38GRCh38
GRCh371177,897,923 - 177,953,419 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,164,865 - 176,205,673 (-)NCBINCBI36Build 36hg18NCBI36
Build 341174,629,937 - 174,670,707NCBI
Celera1151,007,141 - 151,047,948 (-)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1149,125,532 - 149,166,504 (-)NCBIHuRef
CHM1_11179,322,172 - 179,362,966 (-)NCBICHM1_1
T2T-CHM13v2.01177,283,553 - 177,339,057 (-)NCBIT2T-CHM13v2.0
Sec16b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391157,334,303 - 157,395,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1157,334,298 - 157,395,995 (+)EnsemblGRCm39 Ensembl
GRCm381157,506,733 - 157,568,425 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1157,506,728 - 157,568,425 (+)EnsemblGRCm38mm10GRCm38
MGSCv371159,436,927 - 159,498,556 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361159,343,487 - 159,405,102 (+)NCBIMGSCv36mm8
MGSCv361158,657,717 - 158,681,716 (+)NCBIMGSCv36mm8
Celera1159,917,487 - 159,979,158 (+)NCBICelera
Cytogenetic Map1H1NCBI
cM Map168.0NCBI
Sec16b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540617,458,635 - 17,491,920 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540617,458,699 - 17,509,379 (-)NCBIChiLan1.0ChiLan1.0
SEC16B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2171,702,864 - 71,797,859 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1171,411,783 - 71,467,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,445,298 - 153,555,082 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11157,138,640 - 157,179,830 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1157,139,709 - 157,179,830 (-)Ensemblpanpan1.1panPan2
SEC16B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1721,683,310 - 21,739,914 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl721,698,411 - 21,738,954 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha721,210,066 - 21,266,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0721,423,323 - 21,479,479 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl721,423,398 - 21,479,465 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1721,329,712 - 21,386,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0721,437,354 - 21,493,768 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0721,573,233 - 21,629,637 (+)NCBIUU_Cfam_GSD_1.0
Sec16b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934492,936,851 - 92,974,455 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648110,783,054 - 10,821,206 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648110,782,988 - 10,821,204 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC16B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9119,778,664 - 119,842,922 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19119,778,660 - 119,842,962 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29131,339,683 - 131,349,982 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103230534
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12551,309,875 - 51,379,187 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2551,332,937 - 51,380,520 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605552,883,508 - 52,930,698 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec16b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247714,238,976 - 4,274,582 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247714,200,427 - 4,274,020 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec16b
490 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:859
Count of miRNA genes:281
Interacting mature miRNAs:347
Transcripts:ENSRNOT00000007321, ENSRNOT00000044008
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)136906051977046890Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat

Markers in Region
BE108065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21369,705,536 - 69,705,704 (+)MAPPERmRatBN7.2
Rnor_6.01375,195,888 - 75,196,055NCBIRnor6.0
Rnor_5.01380,112,253 - 80,112,420UniSTSRnor5.0
RGSC_v3.41372,808,979 - 72,809,146UniSTSRGSC3.4
Celera1369,533,628 - 69,533,795UniSTS
RH 3.4 Map13411.4UniSTS
Cytogenetic Map13q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB060653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB178524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000007321   ⟹   ENSRNOP00000007321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1375,177,965 - 75,216,933 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000044008   ⟹   ENSRNOP00000046286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,684,291 - 69,727,196 (+)Ensembl
Rnor_6.0 Ensembl1375,175,254 - 75,216,941 (+)Ensembl
RefSeq Acc Id: NM_053571   ⟹   NP_446023
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,217,833 - 72,260,733 (+)NCBI
mRatBN7.21369,684,291 - 69,727,199 (+)NCBI
Rnor_6.01375,175,254 - 75,216,941 (+)NCBI
Rnor_5.01380,090,341 - 80,133,075 (+)NCBI
RGSC_v3.41372,787,822 - 72,830,908 (+)RGD
Celera1369,513,230 - 69,555,087 (+)RGD
Sequence:
RefSeq Acc Id: XM_039091144   ⟹   XP_038947072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,783 - 72,260,733 (+)NCBI
mRatBN7.21369,676,797 - 69,727,199 (+)NCBI
RefSeq Acc Id: XM_039091145   ⟹   XP_038947073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,216,578 - 72,260,733 (+)NCBI
mRatBN7.21369,684,217 - 69,727,199 (+)NCBI
RefSeq Acc Id: XM_039091147   ⟹   XP_038947075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,221,165 - 72,260,733 (+)NCBI
mRatBN7.21369,687,562 - 69,727,199 (+)NCBI
RefSeq Acc Id: XM_063272652   ⟹   XP_063128722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,778 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272653   ⟹   XP_063128723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,814 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272654   ⟹   XP_063128724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,814 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272655   ⟹   XP_063128725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,815 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272656   ⟹   XP_063128726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,214,744 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272657   ⟹   XP_063128727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,216,577 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272658   ⟹   XP_063128728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,778 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272659   ⟹   XP_063128729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,216,578 - 72,260,733 (+)NCBI
RefSeq Acc Id: XM_063272660   ⟹   XP_063128730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81372,206,778 - 72,249,798 (+)NCBI
RefSeq Acc Id: NP_446023   ⟸   NM_053571
- UniProtKB: Q75N33 (UniProtKB/Swiss-Prot),   Q925T1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007321   ⟸   ENSRNOT00000007321
Ensembl Acc Id: ENSRNOP00000046286   ⟸   ENSRNOT00000044008
RefSeq Acc Id: XP_038947072   ⟸   XM_039091144
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947073   ⟸   XM_039091145
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947075   ⟸   XM_039091147
- Peptide Label: isoform X3
- UniProtKB: A6ID32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128722   ⟸   XM_063272652
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128728   ⟸   XM_063272658
- Peptide Label: isoform X2
- UniProtKB: Q925T1 (UniProtKB/Swiss-Prot),   Q75N33 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063128730   ⟸   XM_063272660
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063128723   ⟸   XM_063272653
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128724   ⟸   XM_063272654
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128725   ⟸   XM_063272655
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128726   ⟸   XM_063272656
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128727   ⟸   XM_063272657
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128729   ⟸   XM_063272659
- Peptide Label: isoform X2
- UniProtKB: Q925T1 (UniProtKB/Swiss-Prot),   Q75N33 (UniProtKB/Swiss-Prot)
Protein Domains
Ancestral coatomer element 1 Sec16/Sec31   Sec16 central conserved

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q75N33-F1-model_v2 AlphaFold Q75N33 1-1057 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698922
Promoter ID:EPDNEW_R9447
Type:initiation region
Name:Sec16b_1
Description:SEC16 homolog B, endoplasmic reticulum export factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01375,175,206 - 75,175,266EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621658 AgrOrtholog
BioCyc Gene G2FUF-17791 BioCyc
Ensembl Genes ENSRNOG00000005229 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000044008.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.1030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ACE1_Sec16_Sec31 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec16_CCD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:89868 UniProtKB/Swiss-Prot
NCBI Gene 89868 ENTREZGENE
PANTHER PROTEIN TRANSPORT PROTEIN SEC16B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13402 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec16_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sec16b PhenoGen
RatGTEx ENSRNOG00000005229 RatGTEx
UniProt A6ID32 ENTREZGENE, UniProtKB/TrEMBL
  Q75N33 ENTREZGENE
  Q925T1 ENTREZGENE
  SC16B_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q925T1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-30 Sec16b  SEC16 homolog B, endoplasmic reticulum export factor  Sec16b  SEC16 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Sec16b  SEC16 homolog B (S. cerevisiae)  Lztr2  leucine zipper transcription regulator 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Lztr2  leucine zipper transcription regulator 2  Rgpr  regucalcin gene promotor region related protein  Symbol and Name updated 1299863 APPROVED
2004-02-26 Rgpr  regucalcin gene promotor region related protein      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Rgpr        Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology has greater than 70% identity to human and mouse homologs 633817