Stx6 (syntaxin 6) - Rat Genome Database

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Gene: Stx6 (syntaxin 6) Rattus norvegicus
Analyze
Symbol: Stx6
Name: syntaxin 6
RGD ID: 61915
Description: Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in endocytic recycling; retrograde transport, endosome to Golgi; and synaptic vesicle to endosome fusion. Located in recycling endosome and trans-Golgi network membrane. Is active in synaptic vesicle membrane. Orthologous to human STX6 (syntaxin 6); INTERACTS WITH 2-methoxyethanol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93348; Syn6; syntaxin-6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,882,647 - 69,928,895 (+)NCBIGRCr8
GRCr8 Ensembl1369,882,620 - 69,931,036 (+)EnsemblGRCr8 Ensembl
mRatBN7.21367,332,329 - 67,378,580 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,332,314 - 67,378,576 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,917,560 - 69,963,589 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,231,256 - 71,277,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,491,771 - 68,538,463 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,804,218 - 72,850,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,804,218 - 72,852,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,739,763 - 77,785,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,121,864 - 70,169,379 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,207,720 - 67,253,510 (+)NCBICelera
RGSC_v3.11370,135,943 - 70,183,455 (+)NCBI
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells. Ahras M, etal., J Cell Biol. 2006 Apr 24;173(2):241-51. Epub 2006 Apr 17.
2. A new syntaxin family member implicated in targeting of intracellular transport vesicles. Bock JB, etal., J Biol Chem 1996 Jul 26;271(30):17961-5.
3. Syntaxin 6 functions in trans-Golgi network vesicle trafficking. Bock JB, etal., Mol Biol Cell. 1997 Jul;8(7):1261-71.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors. Koike S and Jahn R, Nat Commun. 2019 Apr 8;10(1):1608. doi: 10.1038/s41467-019-09617-9.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. A novel syntaxin 6-interacting protein, SHIP164, regulates syntaxin 6-dependent sorting from early endosomes. Otto GP, etal., Traffic. 2010 May;11(5):688-705. doi: 10.1111/j.1600-0854.2010.01049.x.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. Richardson SC, etal., Mol Biol Cell 2004 Mar;15(3):1197-210. Epub 2003 Dec 10.
13. Evidence for early endosome-like fusion of recently endocytosed synaptic vesicles. Rizzoli SO, etal., Traffic. 2006 Sep;7(9):1163-76.
14. The Rab5 effector EEA1 interacts directly with syntaxin-6. Simonsen A, etal., J Biol Chem. 1999 Oct 8;274(41):28857-60.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
17. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
Additional References at PubMed
PMID:11384996   PMID:12082176   PMID:12857877   PMID:14622145   PMID:14742717   PMID:15489334   PMID:15689499   PMID:15800058   PMID:15886206   PMID:16154903   PMID:16428329   PMID:17003038  
PMID:17003121   PMID:18406529   PMID:19224922   PMID:19338761   PMID:19620288   PMID:22190682   PMID:22783020   PMID:22871113   PMID:23485813   PMID:23677696   PMID:25799061  


Genomics

Comparative Map Data
Stx6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,882,647 - 69,928,895 (+)NCBIGRCr8
GRCr8 Ensembl1369,882,620 - 69,931,036 (+)EnsemblGRCr8 Ensembl
mRatBN7.21367,332,329 - 67,378,580 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,332,314 - 67,378,576 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,917,560 - 69,963,589 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,231,256 - 71,277,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,491,771 - 68,538,463 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,804,218 - 72,850,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,804,218 - 72,852,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,739,763 - 77,785,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,121,864 - 70,169,379 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,207,720 - 67,253,510 (+)NCBICelera
RGSC_v3.11370,135,943 - 70,183,455 (+)NCBI
Cytogenetic Map13q21NCBI
STX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381180,972,725 - 181,022,870 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1180,972,712 - 181,023,121 (-)EnsemblGRCh38hg38GRCh38
GRCh371180,941,861 - 180,992,006 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,208,798 - 179,258,669 (-)NCBINCBI36Build 36hg18NCBI36
Build 341177,673,835 - 177,723,703NCBI
Celera1154,049,189 - 154,099,059 (-)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,173,031 - 152,222,901 (-)NCBIHuRef
CHM1_11182,364,849 - 182,414,723 (-)NCBICHM1_1
T2T-CHM13v2.01180,327,972 - 180,378,137 (-)NCBIT2T-CHM13v2.0
Stx6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,034,374 - 155,083,405 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,034,461 - 155,084,002 (+)EnsemblGRCm39 Ensembl
GRCm381155,158,628 - 155,207,567 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,158,715 - 155,208,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371157,005,833 - 157,050,647 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361156,920,960 - 156,965,735 (+)NCBIMGSCv36mm8
Celera1157,590,422 - 157,635,333 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.46NCBI
Stx6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540620,048,155 - 20,089,906 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540620,042,552 - 20,089,853 (-)NCBIChiLan1.0ChiLan1.0
STX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,748,337 - 68,798,313 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,406,649 - 68,456,600 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,450,202 - 156,500,143 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,117,825 - 160,167,314 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,117,825 - 160,167,314 (-)Ensemblpanpan1.1panPan2
STX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,452,663 - 14,506,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl714,458,404 - 14,556,917 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,030,381 - 14,083,562 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0714,179,873 - 14,232,084 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl714,184,065 - 14,232,056 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1714,089,893 - 14,143,515 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,196,719 - 14,249,919 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,320,679 - 14,373,902 (-)NCBIUU_Cfam_GSD_1.0
Stx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,515,308 - 90,558,479 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,362,050 - 8,399,737 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,362,059 - 8,405,228 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,529,727 - 122,580,608 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,533,737 - 122,580,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,569,941 - 134,616,721 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12548,380,359 - 48,427,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2548,397,712 - 48,426,676 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605549,763,242 - 49,813,281 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stx6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,227,052 - 1,265,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247711,222,809 - 1,264,662 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Stx6
213 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:134
Interacting mature miRNAs:163
Transcripts:ENSRNOT00000035145
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134760142692601426Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH128466  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21367,378,267 - 67,378,483 (+)MAPPERmRatBN7.2
Rnor_6.01372,850,445 - 72,850,660NCBIRnor6.0
Rnor_5.01377,784,942 - 77,785,157UniSTSRnor5.0
RGSC_v3.41370,169,067 - 70,169,282UniSTSRGSC3.4
Celera1367,253,198 - 67,253,413UniSTS
RH 3.4 Map13359.3UniSTS
Cytogenetic Map13q21UniSTS
RH138891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21367,340,810 - 67,341,016 (+)MAPPERmRatBN7.2
Rnor_6.01372,812,688 - 72,812,893NCBIRnor6.0
Rnor_5.01377,748,233 - 77,748,438UniSTSRnor5.0
RGSC_v3.41370,130,344 - 70,130,549UniSTSRGSC3.4
Celera1367,216,183 - 67,216,388UniSTS
RH 3.4 Map13353.9UniSTS
Cytogenetic Map13q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000035145   ⟹   ENSRNOP00000037536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,882,620 - 69,919,273 (+)Ensembl
mRatBN7.2 Ensembl1367,332,314 - 67,368,957 (+)Ensembl
Rnor_6.0 Ensembl1372,804,218 - 72,852,967 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099649   ⟹   ENSRNOP00000080858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,882,630 - 69,928,891 (+)Ensembl
mRatBN7.2 Ensembl1367,332,329 - 67,378,576 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000128442   ⟹   ENSRNOP00000103517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,882,620 - 69,931,036 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157101   ⟹   ENSRNOP00000109135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,896,977 - 69,928,891 (+)Ensembl
RefSeq Acc Id: NM_031665   ⟹   NP_113853
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,882,647 - 69,928,895 (+)NCBI
mRatBN7.21367,332,329 - 67,378,580 (+)NCBI
Rnor_6.01372,804,218 - 72,850,757 (+)NCBI
Rnor_5.01377,739,763 - 77,785,254 (+)NCBI
RGSC_v3.41370,121,864 - 70,169,379 (+)RGD
Celera1367,207,720 - 67,253,510 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113853 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52709 (Get FASTA)   NCBI Sequence Viewer  
  AAH81769 (Get FASTA)   NCBI Sequence Viewer  
  EDM09512 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000080858.1
  ENSRNOP00000103517
GenBank Protein Q63635 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113853   ⟸   NM_031665
- UniProtKB: Q63635 (UniProtKB/Swiss-Prot),   A6ICY5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037536   ⟸   ENSRNOT00000035145
Ensembl Acc Id: ENSRNOP00000080858   ⟸   ENSRNOT00000099649
Ensembl Acc Id: ENSRNOP00000103517   ⟸   ENSRNOT00000128442
Ensembl Acc Id: ENSRNOP00000109135   ⟸   ENSRNOT00000157101
Protein Domains
t-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63635-F1-model_v2 AlphaFold Q63635 1-255 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698905
Promoter ID:EPDNEW_R9430
Type:initiation region
Name:Stx6_1
Description:syntaxin 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01372,804,245 - 72,804,305EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61915 AgrOrtholog
BioCyc Gene G2FUF-17848 BioCyc
Ensembl Genes ENSRNOG00000003402 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000099649.1 UniProtKB/Swiss-Prot
  ENSRNOT00000128442 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  1.20.58.90 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134641 IMAGE-MGC_LOAD
InterPro SNARE UniProtKB/Swiss-Prot
  Syntaxin-6_N UniProtKB/Swiss-Prot
  Syntaxin/epimorphin_CS UniProtKB/Swiss-Prot
  T_SNARE_dom UniProtKB/Swiss-Prot
KEGG Report rno:60562 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93348 IMAGE-MGC_LOAD
NCBI Gene 60562 ENTREZGENE
PANTHER GOLGI SNARE BET1-RELATED UniProtKB/Swiss-Prot
Pfam SNARE UniProtKB/Swiss-Prot
  Syntaxin-6_N UniProtKB/Swiss-Prot
PhenoGen Stx6 PhenoGen
PROSITE SYNTAXIN UniProtKB/Swiss-Prot
  T_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003402 RatGTEx
SMART t_SNARE UniProtKB/Swiss-Prot
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
  SSF47661 UniProtKB/Swiss-Prot
UniProt A0A8L2QLH0_RAT UniProtKB/TrEMBL
  A6ICY5 ENTREZGENE, UniProtKB/TrEMBL
  Q63635 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Stx6  syntaxin 6       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the Golgi apparatus 61759
gene_function vesicular transport receptor 61759
gene_protein 255 amino acids 61759