STX6 (syntaxin 6) - Rat Genome Database

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Gene: STX6 (syntaxin 6) Chlorocebus sabaeus
Analyze
Symbol: STX6
Name: syntaxin 6
RGD ID: 18725171
Description: ENCODES a protein that exhibits SNAP receptor activity (inferred); SNARE binding (inferred); syntaxin binding (inferred); INVOLVED IN endocytic recycling (ortholog); endosome organization (ortholog); synaptic vesicle to endosome fusion (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 2 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN recycling endosome (ortholog); synaptic vesicle (ortholog); synaptic vesicle membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: syntaxin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12548,380,359 - 48,427,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2548,397,712 - 48,426,676 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605549,763,242 - 49,813,281 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
STX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12548,380,359 - 48,427,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2548,397,712 - 48,426,676 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605549,763,242 - 49,813,281 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381180,972,725 - 181,022,870 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1180,972,712 - 181,023,121 (-)EnsemblGRCh38hg38GRCh38
GRCh371180,941,861 - 180,992,006 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,208,798 - 179,258,669 (-)NCBINCBI36Build 36hg18NCBI36
Build 341177,673,835 - 177,723,703NCBI
Celera1154,049,189 - 154,099,059 (-)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,173,031 - 152,222,901 (-)NCBIHuRef
CHM1_11182,364,849 - 182,414,723 (-)NCBICHM1_1
T2T-CHM13v2.01180,327,972 - 180,378,137 (-)NCBIT2T-CHM13v2.0
Stx6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,034,374 - 155,083,405 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,034,461 - 155,084,002 (+)EnsemblGRCm39 Ensembl
GRCm381155,158,628 - 155,207,567 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,158,715 - 155,208,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371157,005,833 - 157,050,647 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361156,920,960 - 156,965,735 (+)NCBIMGSCv36mm8
Celera1157,590,422 - 157,635,333 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.46NCBI
Stx6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,882,647 - 69,928,895 (+)NCBIGRCr8
mRatBN7.21367,332,329 - 67,378,580 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,332,314 - 67,378,576 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,917,560 - 69,963,589 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,231,256 - 71,277,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,491,771 - 68,538,463 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,804,218 - 72,850,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,804,218 - 72,852,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,739,763 - 77,785,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,121,864 - 70,169,379 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11370,135,943 - 70,183,455 (+)NCBI
Celera1367,207,720 - 67,253,510 (+)NCBICelera
Cytogenetic Map13q21NCBI
Stx6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540620,048,155 - 20,089,906 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540620,042,552 - 20,089,853 (-)NCBIChiLan1.0ChiLan1.0
STX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,748,337 - 68,798,313 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,406,649 - 68,456,600 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,450,202 - 156,500,143 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,117,825 - 160,167,314 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,117,825 - 160,167,314 (-)Ensemblpanpan1.1panPan2
STX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,452,663 - 14,506,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl714,458,404 - 14,556,917 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,030,381 - 14,083,562 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0714,179,873 - 14,232,084 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl714,184,065 - 14,232,056 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1714,089,893 - 14,143,515 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,196,719 - 14,249,919 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,320,679 - 14,373,902 (-)NCBIUU_Cfam_GSD_1.0
Stx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,515,308 - 90,558,479 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,362,050 - 8,399,737 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,362,059 - 8,405,228 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,529,727 - 122,580,608 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,533,737 - 122,580,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,569,941 - 134,616,721 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Stx6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,227,052 - 1,265,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247711,222,809 - 1,264,662 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 18 2 58
Low 18 18 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007989303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCSAT00000010527   ⟹   ENSCSAP00000008621
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2548,397,712 - 48,426,676 (+)Ensembl
RefSeq Acc Id: XM_007989303   ⟹   XP_007987494
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12548,380,359 - 48,427,279 (+)NCBI
Vero_WHO_p1.0NW_02366605549,763,242 - 49,813,281 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007987494 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008621
  ENSCSAP00000008621.1
RefSeq Acc Id: XP_007987494   ⟸   XM_007989303
- UniProtKB: A0A0D9RJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008621   ⟸   ENSCSAT00000010527


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012445 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010527.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/TrEMBL
  1.20.58.90 UniProtKB/TrEMBL
InterPro SNARE UniProtKB/TrEMBL
  Syntaxin-6_N UniProtKB/TrEMBL
  Syntaxin/epimorphin_CS UniProtKB/TrEMBL
  T_SNARE_dom UniProtKB/TrEMBL
NCBI Gene STX6 ENTREZGENE
PANTHER GOLGI SNARE BET1-RELATED UniProtKB/TrEMBL
  SYNTAXIN 6-RELATED UniProtKB/TrEMBL
Pfam SNARE UniProtKB/TrEMBL
  Syntaxin-6_N UniProtKB/TrEMBL
PROSITE SYNTAXIN UniProtKB/TrEMBL
  T_SNARE UniProtKB/TrEMBL
SMART t_SNARE UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/TrEMBL
  SSF47661 UniProtKB/TrEMBL
UniProt A0A0D9RJ32 ENTREZGENE, UniProtKB/TrEMBL