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Gene: Fcgr2b (Fc fragment of IgG receptor IIb) Rattus norvegicus
Symbol: Fcgr2b
Name: Fc fragment of IgG receptor IIb
RGD ID: 631331
Description: Exhibits IgG binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to lipopolysaccharide; and negative regulation of neutrophil apoptotic process. Localizes to cell surface; membrane raft; and recycling endosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to several human genes including FCGR2B (Fc fragment of IgG receptor IIb); PARTICIPATES IN clathrin-mediated endocytosis pathway; adaptive immune response pathway; B cell receptor signaling pathway; INTERACTS WITH (S)-colchicine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2,4-trimethylbenzene.
Type: protein-coding
Also known as: CD32; Fc fragment of IgG, low affinity IIb, receptor; Fc receptor, IgG, low affinity IIb; FC-gamma RII; FcgammaRIIB2; Fcgr2; FCRII; igG Fc receptor II beta; low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma FC region receptor II precursor; low affinity immunoglobulin gamma Fc region receptor II-b
Homo sapiens (human) : FCGR2B (Fc fragment of IgG receptor IIb)  HGNC  Alliance
Mus musculus (house mouse) : Fcgr2b (Fc receptor, IgG, low affinity IIb)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fcgr2b (Fc fragment of IgG receptor IIb)
Pan paniscus (bonobo/pygmy chimpanzee) : FCGR2B (Fc fragment of IgG receptor IIb)
Canis lupus familiaris (dog) : LOC100856270 (low affinity immunoglobulin gamma Fc region receptor II)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fcgr2b (Fc fragment of IgG receptor IIb)
Sus scrofa (pig) : FCGR2B (Fc fragment of IgG, low affinity IIb, receptor (CD32))
Chlorocebus sabaeus (African green monkey) : FCGR2B (Fc fragment of IgG receptor IIb)
Heterocephalus glaber (naked mole-rat) : Fcgr2b (Fc fragment of IgG receptor IIb)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01389,329,298 - 89,343,916 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,327,794 - 89,433,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01393,968,425 - 93,983,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,809,011 - 86,823,599NCBIRGSC3.4rn4RGSC3.4
Celera1382,845,906 - 82,860,494 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Fcgr2b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631331
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.