Dusp12 (dual specificity phosphatase 12) - Rat Genome Database

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Gene: Dusp12 (dual specificity phosphatase 12) Rattus norvegicus
Analyze
Symbol: Dusp12
Name: dual specificity phosphatase 12
RGD ID: 68375
Description: Enables kinase binding activity and phosphoprotein phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Orthologous to human DUSP12 (dual specificity phosphatase 12); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dual specificity protein phosphatase 12; GKAP; glucokinase-associated dual specificity phosphatase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,654,914 - 85,666,431 (-)NCBIGRCr8
mRatBN7.21383,122,192 - 83,131,800 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,122,193 - 83,131,285 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1385,742,087 - 85,751,158 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,035,555 - 87,044,626 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,273,518 - 84,282,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,258,309 - 89,267,402 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,258,310 - 89,267,402 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01393,870,679 - 93,879,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,737,093 - 86,746,186 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11386,751,281 - 86,760,374 (-)NCBI
Celera1382,775,073 - 82,784,182 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate. Munoz-Alonso MJ, etal., J Biol Chem 2000 Oct 20;275(42):32406-12.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10446167   PMID:11432789   PMID:24531476   PMID:36644958  


Genomics

Comparative Map Data
Dusp12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,654,914 - 85,666,431 (-)NCBIGRCr8
mRatBN7.21383,122,192 - 83,131,800 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,122,193 - 83,131,285 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1385,742,087 - 85,751,158 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,035,555 - 87,044,626 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,273,518 - 84,282,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,258,309 - 89,267,402 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,258,310 - 89,267,402 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01393,870,679 - 93,879,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,737,093 - 86,746,186 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11386,751,281 - 86,760,374 (-)NCBI
Celera1382,775,073 - 82,784,182 (-)NCBICelera
Cytogenetic Map13q24NCBI
DUSP12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,749,786 - 161,757,238 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,749,758 - 161,757,238 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,719,576 - 161,727,028 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,986,205 - 159,993,576 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,451,238 - 158,458,609NCBI
Celera1134,823,009 - 134,830,369 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,964,136 - 132,971,867 (+)NCBIHuRef
CHM1_11163,141,376 - 163,148,736 (+)NCBICHM1_1
T2T-CHM13v2.01161,094,105 - 161,101,566 (+)NCBIT2T-CHM13v2.0
Dusp12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,701,756 - 170,713,109 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,701,067 - 170,713,109 (-)EnsemblGRCm39 Ensembl
GRCm381170,874,187 - 170,885,540 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,873,498 - 170,885,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,804,319 - 172,815,671 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,710,863 - 172,722,215 (-)NCBIMGSCv36mm8
Celera1179,989,219 - 180,000,689 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map177.27NCBI
Dusp12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546214,556,094 - 14,565,840 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546214,555,919 - 14,565,046 (-)NCBIChiLan1.0ChiLan1.0
DUSP12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,029,384 - 88,037,407 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1187,697,674 - 87,706,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01137,161,774 - 137,169,503 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,959,867 - 140,968,821 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,959,867 - 140,968,821 (+)Ensemblpanpan1.1panPan2
DUSP12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13820,912,543 - 20,921,137 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3820,912,546 - 20,921,125 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3820,964,899 - 20,973,061 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03820,995,914 - 21,004,157 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3820,995,394 - 21,004,163 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13820,967,831 - 20,975,985 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,320,983 - 21,328,971 (-)NCBIUNSW_CanFamBas_1.0
Dusp12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,636,761 - 7,643,999 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937131156,201 - 163,153 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004937131156,175 - 163,392 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl488,809,565 - 88,818,411 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1488,811,565 - 88,818,513 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2496,827,001 - 96,834,199 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,316,668 - 2,319,972 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660381,353,582 - 1,363,032 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624826168,103 - 182,593 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624826167,966 - 182,844 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dusp12
45 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:139
Count of miRNA genes:112
Interacting mature miRNAs:121
Transcripts:ENSRNOT00000004179
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat

Markers in Region
BE113649  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,130,919 - 83,131,137 (+)MAPPERmRatBN7.2
Rnor_6.01389,267,037 - 89,267,254NCBIRnor6.0
Rnor_5.01393,879,407 - 93,879,624UniSTSRnor5.0
RGSC_v3.41386,745,821 - 86,746,038UniSTSRGSC3.4
Celera1382,783,817 - 82,784,034UniSTS
RH 3.4 Map13551.5UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 8 4 10 4 62 22 32 8
Low 3 37 49 37 9 37 8 11 12 13 8 3 8
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000004179   ⟹   ENSRNOP00000004179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,122,193 - 83,131,285 (-)Ensembl
Rnor_6.0 Ensembl1389,258,310 - 89,267,402 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095378   ⟹   ENSRNOP00000089203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,122,193 - 83,131,267 (-)Ensembl
RefSeq Acc Id: NM_022248   ⟹   NP_071584
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81385,654,914 - 85,664,007 (-)NCBI
mRatBN7.21383,122,192 - 83,131,285 (-)NCBI
Rnor_6.01389,258,309 - 89,267,402 (-)NCBI
Rnor_5.01393,870,679 - 93,879,772 (-)NCBI
RGSC_v3.41386,737,093 - 86,746,186 (-)RGD
Celera1382,775,073 - 82,784,182 (-)RGD
Sequence:
RefSeq Acc Id: XM_039091059   ⟹   XP_038946987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81385,655,240 - 85,666,431 (-)NCBI
mRatBN7.21383,122,518 - 83,131,800 (-)NCBI
Protein Sequences
Protein RefSeqs NP_071584 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946987 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF87971 (Get FASTA)   NCBI Sequence Viewer  
  EDM09243 (Get FASTA)   NCBI Sequence Viewer  
  EDM09244 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004179
  ENSRNOP00000004179.2
  ENSRNOP00000089203.1
  ENSRNOP00065037961
GenBank Protein Q9JIM4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071584   ⟸   NM_022248
- UniProtKB: Q9JIM4 (UniProtKB/Swiss-Prot),   A0A8I6AB94 (UniProtKB/TrEMBL),   A6IDQ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004179   ⟸   ENSRNOT00000004179
RefSeq Acc Id: XP_038946987   ⟸   XM_039091059
- Peptide Label: isoform X1
- UniProtKB: A6IDQ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089203   ⟸   ENSRNOT00000095378
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JIM4-F1-model_v2 AlphaFold Q9JIM4 1-339 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698988
Promoter ID:EPDNEW_R9513
Type:initiation region
Name:Dusp12_1
Description:dual specificity phosphatase 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,267,387 - 89,267,447EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68375 AgrOrtholog
BioCyc Gene G2FUF-17465 BioCyc
Ensembl Genes ENSRNOG00000003100 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00065026821 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004179 ENTREZGENE
  ENSRNOT00000004179.4 UniProtKB/Swiss-Prot
  ENSRNOT00000095378.1 UniProtKB/TrEMBL
  ENSRNOT00065046281 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUSP12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64014 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene Dusp12 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dusp12 PhenoGen
PIRSF DUSP12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003100 RatGTEx
  ENSRNOG00065026821 RatGTEx
SMART DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC209833
UniProt A0A8I6AB94 ENTREZGENE, UniProtKB/TrEMBL
  A6IDQ3 ENTREZGENE, UniProtKB/TrEMBL
  A6IDQ4 ENTREZGENE, UniProtKB/TrEMBL
  DUS12_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Dusp12  dual specificity phosphatase 12      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the cytosol and not the nucleus 68242
gene_function interacts with liver glucokinase 68242
gene_function dephosphorylates recombinant glucokinase 68242
gene_protein 339 amino acids 68242