Hspa6l-ps1 (heat shock protein family A (Hsp70) member 6 like, pseudogene 1) - Rat Genome Database

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Gene: Hspa6l-ps1 (heat shock protein family A (Hsp70) member 6 like, pseudogene 1) Rattus norvegicus
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Symbol: Hspa6l-ps1
Name: heat shock protein family A (Hsp70) member 6 like, pseudogene 1
RGD ID: 1586661
Description: Predicted to enable several functions, including ATP hydrolysis activity; heat shock protein binding activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat and protein refolding. Predicted to be located in centriole and cytosol. Predicted to be part of COP9 signalosome; INTERACTS WITH (E)-cinnamyl alcohol (ortholog); 1,3-benzothiazole-2-thiol (ortholog); 1,4-phenylenediamine (ortholog).
Type: pseudo
RefSeq Status: INFERRED
Previously known as: heat shock 70 kDa protein 6; LOC686035; similar to heat shock 70kDa protein 6 (HSP70B)
RGD Orthologs
Human
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,805,911 - 85,807,052 (-)NCBIGRCr8
mRatBN7.21383,273,176 - 83,274,317 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01389,408,703 - 89,411,500 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,048,282 - 94,050,425 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,890,753 - 86,892,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1382,925,184 - 82,927,981 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(E)-cinnamyl alcohol  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,6-dichloroindophenol  (ISO)
2-bromo-2-(bromomethyl)pentanedinitrile  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-nitrobenzyl bromide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium hexachloroplatinate  (ISO)
amphibole asbestos  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
Aurin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
boron nitride  (ISO)
bortezomib  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
chloropicrin  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-penicillamine  (ISO)
deguelin  (ISO)
desferrioxamine B  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dieldrin  (ISO)
diethyl maleate  (ISO)
dihydroxyacetone  (ISO)
diquat  (ISO)
disulfiram  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
elesclomol  (ISO)
ethanol  (ISO)
eugenol  (ISO)
formaldehyde  (ISO)
glycerol  (ISO)
glyoxal  (ISO)
glyphosate  (ISO)
hexamethylene diisocyanate  (ISO)
hydrogen peroxide  (ISO)
indirubin-3'-monoxime  (ISO)
iron dichloride  (ISO)
isoeugenol  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
mercury dichloride  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
o-anisidine  (ISO)
ochratoxin A  (ISO)
organoselenium compound  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
progesterone  (ISO)
pyrimidifen  (ISO)
quartz  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tanespimycin  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
thimerosal  (ISO)
thiostrepton  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trans-isoeugenol  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc molecular entity  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriole  (ISO)
COP9 signalosome  (ISO)
cytoplasm  (ISO)
cytosol  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Hspa6l-ps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,805,911 - 85,807,052 (-)NCBIGRCr8
mRatBN7.21383,273,176 - 83,274,317 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01389,408,703 - 89,411,500 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,048,282 - 94,050,425 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,890,753 - 86,892,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1382,925,184 - 82,927,981 (-)NCBICelera
Cytogenetic Map13q24NCBI
HSPA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,524,540 - 161,526,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,524,540 - 161,526,894 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,494,330 - 161,496,684 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,760,660 - 159,763,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,307,090 - 158,309,740NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,819,052 - 132,821,703 (+)NCBIHuRef
CHM1_11162,915,872 - 162,918,523 (+)NCBICHM1_1
T2T-CHM13v2.01160,787,168 - 160,789,522 (+)NCBIT2T-CHM13v2.0
Hspa6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546214,723,990 - 14,726,420 (-)NCBIChiLan1.0ChiLan1.0
HSPA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,261,128 - 88,266,004 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1187,929,563 - 87,934,439 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,911,131 - 136,914,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Hspa6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,505,973 - 7,508,940 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493713125,551 - 28,457 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493713125,603 - 28,458 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl488,970,599 - 88,973,918 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1488,970,592 - 88,973,109 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HSPA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,490,826 - 2,495,376 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660381,549,052 - 1,551,883 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspa6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482634,585 - 37,217 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462482635,284 - 37,573 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hspa6l-ps1
25 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression


Sequence


RefSeq Acc Id: XM_008762767   ⟹   XP_008760989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1382,925,184 - 82,927,981 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769766   ⟹   XP_008767988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,408,703 - 89,411,500 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-17452 BioCyc
NCBI Gene 686035 ENTREZGENE
PhenoGen Hspa6l-ps1 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Hspa6l-ps1  heat shock protein family A (Hsp70) member 6 like, pseudogene 1  LOC686035  similar to heat shock 70kDa protein 6 (HSP70B)  Symbol and Name Changed 1299863 APPROVED
2006-11-19 LOC686035  similar to heat shock 70kDa protein 6 (HSP70B)      Symbol and Name status set to provisional 70820 PROVISIONAL