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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | decreases expression | ISO | RGD:1614318 | 6480464 | Estradiol results in decreased expression of ANGPTL1 mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of ANGPTL1 mRNA, [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ANGPTL1 mRNA | CTD | PMID:26496021, PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ANGPTL1 mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1614318 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ANGPTL1 mRNA | CTD | PMID:21354282 | 2-hydroxypropanoic acid | increases expression | ISO | RGD:1347249 | 6480464 | Lactic Acid results in increased expression of ANGPTL1 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1347249 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANGPTL1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1614318 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of ANGPTL1 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1614318 | 6480464 | Fenretinide results in decreased expression of ANGPTL1 mRNA | CTD | PMID:28973697 | 8-Br-cAMP | decreases expression | ISO | RGD:1347249 | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ANGPTL1 mRNA | CTD | PMID:22079614 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of ANGPTL1 mRNA | CTD | PMID:28959563 | arsenous acid | decreases expression | ISO | RGD:1347249 | 6480464 | Arsenic Trioxide results in decreased expression of ANGPTL1 mRNA | CTD | PMID:26705709 | benzo[a]pyrene | decreases expression | ISO | RGD:1347249 | 6480464 | Benzo(a)pyrene results in decreased expression of ANGPTL1 mRNA | CTD | PMID:20106945, PMID:21632981 | benzo[a]pyrene | increases expression | ISO | RGD:1347249 | 6480464 | Benzo(a)pyrene results in increased expression of ANGPTL1 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | decreases expression | ISO | RGD:1614318 | 6480464 | Benzo(a)pyrene results in decreased expression of ANGPTL1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | increases expression | ISO | RGD:1347249 | 6480464 | 7 more ... | CTD | PMID:26238291 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1347249 | 6480464 | Diethylhexyl Phthalate results in decreased expression of ANGPTL1 mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of ANGPTL1 mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | ISO | RGD:1614318 | 6480464 | bisphenol A results in increased expression of ANGPTL1 mRNA | CTD | PMID:30951980 | bisphenol A | multiple interactions | ISO | RGD:1347249 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANGPTL1 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ANGPTL1 mRNA | CTD | PMID:25181051, PMID:34947998 | bisphenol F | increases expression | ISO | RGD:1614318 | 6480464 | bisphenol F results in increased expression of ANGPTL1 mRNA | CTD | PMID:30951980 | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of ANGPTL1 mRNA | CTD | PMID:32479839 | buta-1,3-diene | decreases expression | ISO | RGD:1614318 | 6480464 | 1, 3-butadiene results in decreased expression of ANGPTL1 mRNA | CTD | PMID:29038090 | copper(II) sulfate | decreases expression | ISO | RGD:1347249 | 6480464 | Copper Sulfate results in decreased expression of ANGPTL1 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | RGD:1347249 | 6480464 | Cyclosporine results in decreased expression of ANGPTL1 mRNA | CTD | PMID:25562108 | dexamethasone | increases expression | ISO | RGD:1347249 | 6480464 | Dexamethasone results in increased expression of ANGPTL1 mRNA | CTD | PMID:25047013 | dexamethasone | multiple interactions | ISO | RGD:1347249 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANGPTL1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | RGD:1347249 | 6480464 | Arsenic Trioxide results in decreased expression of ANGPTL1 mRNA | CTD | PMID:26705709 | dicrotophos | decreases expression | ISO | RGD:1347249 | 6480464 | dicrotophos results in decreased expression of ANGPTL1 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of ANGPTL1 mRNA | CTD | PMID:33729688 | doxorubicin | decreases expression | ISO | RGD:1347249 | 6480464 | Doxorubicin results in decreased expression of ANGPTL1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ANGPTL1 mRNA | CTD | PMID:29391264 | folic acid | increases expression | ISO | RGD:1614318 | 6480464 | Folic Acid results in increased expression of ANGPTL1 mRNA | CTD | PMID:25629700 | geldanamycin | decreases expression | ISO | RGD:1347249 | 6480464 | geldanamycin results in decreased expression of ANGPTL1 mRNA | CTD | PMID:26705709 | genistein | affects expression | ISO | RGD:1614318 | 6480464 | Genistein affects the expression of ANGPTL1 mRNA | CTD | PMID:32186404 | indometacin | multiple interactions | ISO | RGD:1347249 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANGPTL1 mRNA | CTD | PMID:28628672 | lead diacetate | decreases expression | ISO | RGD:1614318 | 6480464 | lead acetate results in decreased expression of ANGPTL1 mRNA | CTD | PMID:22609695 | leflunomide | decreases expression | ISO | RGD:1347249 | 6480464 | leflunomide results in decreased expression of ANGPTL1 mRNA | CTD | PMID:28988120 | mancozeb | decreases expression | ISO | RGD:1347249 | 6480464 | mancozeb results in decreased expression of ANGPTL1 mRNA | CTD | PMID:33396126 | nickel atom | decreases expression | ISO | RGD:1347249 | 6480464 | Nickel results in decreased expression of ANGPTL1 mRNA | CTD | PMID:24768652, PMID:25583101 | pirinixic acid | multiple interactions | ISO | RGD:1347249 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ANGPTL1 mRNA | CTD | PMID:19710929 | potassium dichromate | decreases expression | ISO | RGD:1614318 | 6480464 | Potassium Dichromate results in decreased expression of ANGPTL1 mRNA | CTD | PMID:23608068 | progesterone | increases expression | ISO | RGD:1614318 | 6480464 | Progesterone results in increased expression of ANGPTL1 mRNA | CTD | PMID:22350948 | progesterone | multiple interactions | ISO | RGD:1614318 | 6480464 | [Progesterone co-treated with Estrogens] results in increased expression of ANGPTL1 mRNA | CTD | PMID:22350948 | rac-lactic acid | increases expression | ISO | RGD:1347249 | 6480464 | Lactic Acid results in increased expression of ANGPTL1 mRNA | CTD | PMID:30851411 | rofecoxib | decreases expression | ISO | RGD:1347249 | 6480464 | rofecoxib results in decreased expression of ANGPTL1 mRNA | CTD | PMID:17070997 | sodium fluoride | increases expression | ISO | RGD:1614318 | 6480464 | Sodium Fluoride results in increased expression of ANGPTL1 mRNA | CTD | PMID:27862939 | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ANGPTL1 mRNA | CTD | PMID:32741896 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of ANGPTL1 gene | CTD | PMID:27618143 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ANGPTL1 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | RGD:1347249 | 6480464 | trichostatin A results in decreased expression of ANGPTL1 mRNA | CTD | PMID:26705709 | triclosan | decreases expression | ISO | RGD:1347249 | 6480464 | Triclosan results in decreased expression of ANGPTL1 mRNA | CTD | PMID:30510588 | urethane | decreases expression | ISO | RGD:1347249 | 6480464 | Urethane results in decreased expression of ANGPTL1 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | RGD:1347249 | 6480464 | Valproic Acid results in decreased methylation of ANGPTL1 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1614318 | 6480464 | Valproic Acid results in increased expression of ANGPTL1 mRNA | CTD | PMID:24896083 | valproic acid | affects expression | ISO | RGD:1347249 | 6480464 | Valproic Acid affects the expression of ANGPTL1 mRNA | CTD | PMID:25979313 | vanadyl sulfate | increases expression | ISO | RGD:1347249 | 6480464 | vanadyl sulfate results in increased expression of ANGPTL1 mRNA | CTD | PMID:16330358 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ANGPTL1 mRNA | CTD | PMID:23034163 | |