Gene: Prdx6 (peroxiredoxin 6) Rattus norvegicus
Analyze
Symbol:
Prdx6
Name:
peroxiredoxin 6
Description:
Exhibits glutathione peroxidase activity. Involved in hydrogen peroxide catabolic process. Predicted to localize to the cytosol; nucleus; and perinuclear region of cytoplasm. Orthologous to human PRDX6 (peroxiredoxin 6); PARTICIPATES IN phenylalanine metabolic pathway; INTERACTS WITH (R)-adrenaline; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
1-Cys peroxiredoxin; 1-Cys PRX; acidic calcium-independent phospholipase A2; aiPLA2; antioxidant protein 2; non-selenium glutathione peroxidase; NSGPx; peroxiredoxin-6; thiol-specific antioxidant protein
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PRDX6 (peroxiredoxin 6) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Prdx6 (peroxiredoxin 6) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Prdx6 (peroxiredoxin 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PRDX6 (peroxiredoxin 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PRDX6 (peroxiredoxin 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Prdx6 (peroxiredoxin 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PRDX6 (peroxiredoxin 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Prdx6 (peroxiredoxin 6)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
PRDX6 (peroxiredoxin 6)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Prdx6b (peroxiredoxin 6B)
Alliance
DIOPT (Ensembl Compara, OrthoFinder, PANTHER, TreeFam)
Danio rerio (zebrafish):
prdx6 (peroxiredoxin 6)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
CG12896
Alliance
DIOPT (Ensembl Compara, Hieranoid, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Saccharomyces cerevisiae (baker's yeast):
PRX1
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
prdx-6
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):
Prx2540-1
Alliance
DIOPT (Ensembl Compara, Hieranoid, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
Prx2540-2
Alliance
DIOPT (Ensembl Compara, Hieranoid, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
Prx6005
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 13 79,077,567 - 79,088,113 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 79,077,033 - 79,088,127 (-) Ensembl Rnor_5.0 13 83,972,564 - 83,983,110 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 76,824,968 - 76,835,517 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 13 76,838,625 - 76,849,719 (-) NCBI Celera 13 73,317,100 - 73,327,649 (-) NCBI Celera Cytogenetic Map 13 q22 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
1q24 Deletion Syndrome ISO RGD:1602898 8554872 ClinVar Annotator: match by term: 1q24q25 microdeletion syndrome ClinVar PMID:25741868 1q24 Deletion Syndrome ISO RGD:1602898 8554872 ClinVar Annotator: match by term: 1q24q25 microdeletion syndrome ClinVar PMID:21548129 more ...
Imported Annotations - CTD
adult respiratory distress syndrome ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25070658 contact dermatitis ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25724174 Down syndrome ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:11771762 hepatocellular carcinoma ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21472284 Lung Neoplasms ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:23692979 Myocardial Ischemia ISO RGD:1602898 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16214533
(R)-adrenaline multiple interactions EXP 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PRDX6 protein CTD PMID:19464573 (R)-adrenaline decreases expression EXP 6480464 Epinephrine results in decreased expression of PRDX6 protein CTD PMID:19464573 1,2-Naphthoquinone multiple interactions ISO RGD:1602898 6480464 1, 2-naphthoquinone binds to and results in decreased activity of PRDX6 protein CTD PMID:22129745 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:1602898 6480464 Metribolone results in increased expression of PRDX6 protein CTD PMID:17152098 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PRDX6 protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PRDX6 mRNA CTD PMID:26232522 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736132 6480464 Tetrachlorodibenzodioxin affects the expression of PRDX6 mRNA CTD PMID:21570461 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of PRDX6 mRNA CTD PMID:21346803 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of PRDX6 protein CTD PMID:26597043 4,4'-diaminodiphenylmethane decreases expression ISO RGD:736132 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of PRDX6 mRNA CTD PMID:18648102 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PRDX6 protein CTD PMID:23692979 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of PRDX6 mRNA CTD PMID:21346803 5-aza-2'-deoxycytidine affects methylation ISO RGD:1602898 6480464 Decitabine affects the methylation of PRDX6 gene CTD PMID:17630775 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of PRDX6 mRNA CTD PMID:19483382 7H-xanthine multiple interactions EXP 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PRDX6 protein CTD PMID:19464573 9H-xanthine multiple interactions EXP 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PRDX6 protein CTD PMID:19464573 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased expression of PRDX6 mRNA], Dactinomycin inhibits the reaction [Paraquat results in increased expression of PRDX6 mRNA] CTD PMID:12851211 aflatoxin B1 decreases methylation ISO RGD:1602898 6480464 Aflatoxin B1 results in decreased methylation of PRDX6 gene CTD PMID:27153756 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of PRDX6 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PRDX6 mRNA CTD PMID:16483693 arsane increases expression ISO RGD:1602898 6480464 Arsenic results in increased expression of PRDX6 mRNA CTD PMID:19945496 arsenic atom increases expression ISO RGD:1602898 6480464 Arsenic results in increased expression of PRDX6 mRNA CTD PMID:19945496 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of PRDX6 mRNA CTD PMID:19483382 benzo[a]pyrene increases expression ISO RGD:736132 6480464 Benzo(a)pyrene results in increased expression of PRDX6 mRNA CTD PMID:21569818 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of PRDX6 mRNA CTD PMID:16648578 bisphenol A multiple interactions EXP 6480464 [Fructose co-treated with bisphenol A] results in increased expression of PRDX6 protein CTD PMID:26930160 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PRDX6 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PRDX6 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:736132 6480464 bisphenol A results in increased expression of PRDX6 mRNA CTD PMID:26063408 bleomycin A2 decreases expression EXP 6480464 Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 bromobenzene affects binding EXP 6480464 bromobenzene metabolite binds to PRDX6 protein CTD PMID:17305373 buta-1,3-diene increases expression ISO RGD:736132 6480464 1, 3-butadiene results in increased expression of PRDX6 mRNA CTD PMID:29038090 cadmium atom increases expression ISO RGD:1602898 6480464 Cadmium results in increased expression of PRDX6 protein CTD PMID:16440303 cadmium dichloride increases expression ISO RGD:1602898 6480464 Cadmium Chloride results in increased expression of PRDX6 protein CTD PMID:16440303 calcitriol multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 calcium atom multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 calcium(0) multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 capsaicin increases expression ISO RGD:1602898 6480464 Capsaicin results in increased expression of PRDX6 protein CTD PMID:18991268 carbon nanotube affects expression ISO RGD:1602898 6480464 Nanotubes, Carbon affects the expression of PRDX6 protein CTD PMID:22001959 carbon nanotube multiple interactions ISO RGD:736132 6480464 [Nanotubes, Carbon co-treated with Polysorbates] results in increased expression of PRDX6 protein CTD PMID:28807745 carbon nanotube decreases expression ISO RGD:736132 6480464 Nanotubes, Carbon analog results in decreased expression of PRDX6 mRNA, Nanotubes, Carbon results in decreased expression of PRDX6 mRNA CTD PMID:25620056 carbon nanotube affects expression ISO RGD:736132 6480464 Nanotubes, Carbon affects the expression of PRDX6 mRNA, Nanotubes, Carbon analog affects the expression of PRDX6 mRNA CTD PMID:25554681 carbon nanotube increases expression ISO RGD:1602898 6480464 Nanotubes, Carbon results in increased expression of PRDX6 protein CTD PMID:22157353 cisplatin multiple interactions ISO RGD:1602898 6480464 PRDX6 protein inhibits the reaction [Cisplatin results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:21166495 cisplatin decreases expression ISO RGD:736132 6480464 Cisplatin results in decreased expression of PRDX6 mRNA CTD PMID:24865317 cisplatin multiple interactions ISO RGD:736132 6480464 [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA CTD PMID:24865317 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of PRDX6 mRNA CTD PMID:19483382 clofibrate decreases expression ISO RGD:736132 6480464 Clofibrate results in decreased expression of PRDX6 mRNA CTD PMID:17585979 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of PRDX6 mRNA, cobaltous chloride results in decreased expression of PRDX6 protein CTD PMID:20923568 copper atom affects binding ISO RGD:1602898 6480464 PRDX6 protein binds to Copper CTD PMID:15359738 copper(0) affects binding ISO RGD:1602898 6480464 PRDX6 protein binds to Copper CTD PMID:15359738 CU-O LINKAGE increases expression ISO RGD:1602898 6480464 cupric oxide results in increased expression of PRDX6 protein CTD PMID:25470785 CU-O LINKAGE decreases expression ISO RGD:736132 6480464 cupric oxide results in decreased expression of PRDX6 protein CTD PMID:23882024 cumene hydroperoxide increases expression ISO RGD:1602898 6480464 cumene hydroperoxide results in increased expression of PRDX6 protein CTD PMID:11295360 dexamethasone increases expression ISO RGD:1602898 6480464 Dexamethasone results in increased expression of PRDX6 mRNA CTD PMID:25047013 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of PRDX6 protein CTD PMID:26721910 diethyldithiocarbamic acid increases expression EXP 6480464 Ditiocarb results in increased expression of PRDX6 protein CTD PMID:22874009 dioxygen increases expression ISO RGD:736132 6480464 Oxygen results in increased expression of PRDX6 mRNA, Oxygen results in increased expression of PRDX6 protein CTD PMID:12851211 dioxygen affects response to substance ISO RGD:736132 6480464 PRDX6 protein affects the susceptibility to Oxygen CTD PMID:20627125 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of PRDX6 mRNA, Oxygen deficiency results in decreased expression of PRDX6 protein CTD PMID:20923568 dioxygen increases expression EXP 6480464 Oxygen results in increased expression of PRDX6 mRNA, Oxygen results in increased expression of PRDX6 protein CTD PMID:12851211 doxorubicin multiple interactions ISO RGD:736132 6480464 [Doxorubicin co-treated with MT2A protein] results in increased expression of PRDX6 protein more ... CTD PMID:16144979 , PMID:21463615 doxorubicin increases expression ISO RGD:1602898 6480464 Doxorubicin results in increased expression of PRDX6 mRNA CTD PMID:29803840 doxorubicin increases oxidation EXP 6480464 Doxorubicin results in increased oxidation of PRDX6 protein CTD PMID:28818578 doxorubicin increases expression ISO RGD:736132 6480464 Doxorubicin results in increased expression of PRDX6 mRNA, Doxorubicin results in increased expression of PRDX6 protein CTD PMID:21463615 emodin increases expression ISO RGD:1602898 6480464 Emodin results in increased expression of PRDX6 mRNA CTD PMID:16045814 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of PRDX6 mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO RGD:1602898 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PRDX6 protein CTD PMID:23301498 ethanol decreases expression ISO RGD:1602898 6480464 Ethanol results in decreased expression of PRDX6 protein CTD PMID:20621659 ethanol multiple interactions ISO RGD:736132 6480464 Ethanol affects the expression of and affects the splicing of PRDX6 mRNA CTD PMID:30319688 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PRDX6 mRNA CTD PMID:24136188 folic acid affects expression EXP 6480464 Folic Acid affects the expression of PRDX6 protein CTD PMID:16251605 fructose multiple interactions EXP 6480464 [Fructose co-treated with bisphenol A] results in increased expression of PRDX6 protein CTD PMID:26930160 fumonisin B1 decreases expression ISO RGD:736132 6480464 fumonisin B1 results in decreased expression of PRDX6 mRNA CTD PMID:16221962 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of PRDX6 mRNA CTD PMID:15345336 herbicide multiple interactions ISO RGD:736132 6480464 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Herbicides results in decreased expression of PRDX6 mRNA], Herbicides inhibits the reaction [arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide results in increased expression of PRDX6 mRNA] CTD PMID:21318024 herbicide decreases expression ISO RGD:736132 6480464 Herbicides results in decreased expression of PRDX6 mRNA CTD PMID:21318024 homocysteine multiple interactions ISO RGD:1602898 6480464 [Methionine deficiency co-treated with Homocysteine] affects the expression of PRDX6 protein CTD PMID:17116298 hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PRDX6 protein] CTD PMID:23178681 hyaluronic acid affects expression EXP 6480464 Hyaluronic Acid analog affects the expression of PRDX6 protein CTD PMID:23178681 hydrogen peroxide increases expression ISO RGD:1602898 6480464 Hydrogen Peroxide results in increased expression of PRDX6 protein CTD PMID:11295360 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of PRDX6 protein CTD PMID:23178681 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of PRDX6 mRNA CTD PMID:12851211 hydrogen peroxide multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:12851211 , PMID:23178681 hydrogen peroxide increases response to substance ISO RGD:736132 6480464 PRDX6 gene mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:12732627 hydrogen peroxide decreases response to substance ISO RGD:1602898 6480464 PRDX6 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:14741336 ibuprofen affects expression ISO RGD:1602898 6480464 Ibuprofen affects the expression of PRDX6 protein CTD PMID:18351690 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of PRDX6 mRNA CTD PMID:19483382 L-methionine multiple interactions ISO RGD:1602898 6480464 [Methionine deficiency co-treated with Homocysteine] affects the expression of PRDX6 protein CTD PMID:17116298 lipopolysaccharide multiple interactions ISO RGD:736132 6480464 PRDX6 protein inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] more ... CTD PMID:21200322 lutein decreases expression ISO RGD:736132 6480464 Lutein results in decreased expression of PRDX6 mRNA CTD PMID:24865317 lutein multiple interactions ISO RGD:736132 6480464 [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA CTD PMID:24865317 manganese atom affects expression EXP 6480464 Manganese affects the expression of PRDX6 protein CTD PMID:24885898 manganese(0) affects expression EXP 6480464 Manganese affects the expression of PRDX6 protein CTD PMID:24885898 mercury atom decreases expression ISO RGD:1602898 6480464 Mercury results in decreased expression of PRDX6 mRNA CTD PMID:16823088 mercury atom increases expression ISO RGD:736132 6480464 Mercury analog results in increased expression of PRDX6 mRNA CTD PMID:25056781 mercury(0) decreases expression ISO RGD:1602898 6480464 Mercury results in decreased expression of PRDX6 mRNA CTD PMID:16823088 mercury(0) increases expression ISO RGD:736132 6480464 Mercury analog results in increased expression of PRDX6 mRNA CTD PMID:25056781 methylene blue multiple interactions ISO RGD:736132 6480464 [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of PRDX6 mRNA CTD PMID:24556215 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX6 mRNA CTD PMID:28659758 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PRDX6 protein CTD PMID:20600802 naphthalene affects binding ISO RGD:736132 6480464 naphthalene metabolite binds to PRDX6 protein CTD PMID:15892573 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PRDX6 mRNA CTD PMID:24136188 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of PRDX6 mRNA CTD PMID:24136188 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of PRDX6 protein CTD PMID:19260726 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of PRDX6 protein CTD PMID:19260726 obeticholic acid decreases expression ISO RGD:1602898 6480464 obeticholic acid results in decreased expression of PRDX6 mRNA CTD PMID:27939613 ochratoxin A increases expression ISO RGD:736132 6480464 ochratoxin A results in increased expression of PRDX6 protein CTD PMID:19445961 okadaic acid multiple interactions ISO RGD:1602898 6480464 [Okadaic Acid co-treated with gambierol] results in decreased expression of PRDX6 protein CTD PMID:19397276 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of PRDX6 mRNA CTD PMID:19483382 paracetamol affects expression ISO RGD:736132 6480464 Acetaminophen affects the expression of PRDX6 mRNA CTD PMID:17562736 paracetamol multiple interactions ISO RGD:736132 6480464 [CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in decreased expression of PRDX6 protein CTD PMID:25499718 paraquat multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:12851211 paraquat affects response to substance ISO RGD:736132 6480464 PRDX6 protein affects the susceptibility to Paraquat CTD PMID:20713718 paraquat increases response to substance ISO RGD:736132 6480464 PRDX6 gene mutant form results in increased susceptibility to Paraquat CTD PMID:12732627 paraquat increases expression EXP 6480464 Paraquat results in increased expression of PRDX6 mRNA CTD PMID:12851211 paraquat affects expression EXP 6480464 Paraquat affects the expression of PRDX6 mRNA CTD PMID:16854511 paraquat decreases response to substance ISO RGD:736132 6480464 PRDX6 protein results in decreased susceptibility to Paraquat CTD PMID:16487056 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of PRDX6 mRNA CTD PMID:16221955 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of PRDX6 mRNA CTD PMID:16221955 perfluorooctanoic acid increases expression ISO RGD:1602898 6480464 perfluorooctanoic acid results in increased expression of PRDX6 protein CTD PMID:26879310 permethrin multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX6 mRNA CTD PMID:28659758 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of PRDX6 mRNA CTD PMID:19162173 phenobarbital affects expression ISO RGD:736132 6480464 Phenobarbital affects the expression of PRDX6 mRNA CTD PMID:23091169 picloram multiple interactions ISO RGD:736132 6480464 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX6 mRNA] CTD PMID:21318024 picloram decreases expression ISO RGD:736132 6480464 Picloram results in decreased expression of PRDX6 mRNA CTD PMID:21318024 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of PRDX6 mRNA CTD PMID:19483382 pirinixic acid decreases expression ISO RGD:736132 6480464 pirinixic acid results in decreased expression of PRDX6 protein CTD PMID:15226431 propiconazole increases metabolic processing ISO RGD:736132 6480464 propiconazole results in increased metabolism of PRDX6 protein CTD PMID:19714882 Propiverine affects binding EXP 6480464 propiverine binds to PRDX6 protein CTD PMID:29273565 Pyridostigmine bromide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX6 mRNA CTD PMID:28659758 pyrogallol increases expression ISO RGD:736132 6480464 Pyrogallol results in increased expression of PRDX6 mRNA CTD PMID:20362636 quartz decreases expression ISO RGD:1602898 6480464 Quartz results in decreased expression of PRDX6 protein CTD PMID:27917503 quercetin multiple interactions ISO RGD:736132 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRDX6 mRNA] CTD PMID:25471833 quercetin increases expression EXP 6480464 Quercetin results in increased expression of PRDX6 mRNA CTD PMID:18095365 reactive oxygen species multiple interactions ISO RGD:1602898 6480464 PRDX6 protein inhibits the reaction [Cisplatin results in increased abundance of Reactive Oxygen Species] CTD PMID:21166495 resveratrol decreases expression ISO RGD:1602898 6480464 resveratrol results in decreased expression of PRDX6 protein CTD PMID:23724044 rotenone affects expression ISO RGD:736132 6480464 Rotenone affects the expression of PRDX6 mRNA CTD PMID:23186747 sarin decreases expression EXP 6480464 Sarin results in decreased expression of PRDX6 protein CTD PMID:28973502 SB 431542 increases expression ISO RGD:1602898 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of PRDX6 protein CTD PMID:25670856 silicon dioxide increases secretion ISO RGD:1602898 6480464 Silicon Dioxide analog results in increased secretion of PRDX6 protein CTD PMID:25895662 silver atom affects expression ISO RGD:736132 6480464 Silver affects the expression of PRDX6 mRNA CTD PMID:19429238 silver atom increases expression ISO RGD:736132 6480464 Silver results in increased expression of PRDX6 mRNA CTD PMID:22576574 silver(0) affects expression ISO RGD:736132 6480464 Silver affects the expression of PRDX6 mRNA CTD PMID:19429238 silver(0) increases expression ISO RGD:736132 6480464 Silver results in increased expression of PRDX6 mRNA CTD PMID:22576574 sodium arsenate increases expression ISO RGD:736132 6480464 sodium arsenate results in increased expression of PRDX6 mRNA CTD PMID:30953684 sodium arsenite decreases expression ISO RGD:1602898 6480464 sodium arsenite results in decreased expression of PRDX6 protein CTD PMID:21925251 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of PRDX6 protein CTD PMID:29459688 sodium arsenite increases expression ISO RGD:736132 6480464 sodium arsenite results in increased expression of PRDX6 mRNA CTD PMID:17450228 sodium fluoride decreases expression ISO RGD:736132 6480464 Sodium Fluoride results in decreased expression of PRDX6 protein CTD PMID:28918527 streptozocin multiple interactions ISO RGD:1602898 6480464 PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA] CTD PMID:20446767 streptozocin decreases expression ISO RGD:736132 6480464 Streptozocin results in decreased expression of PRDX6 mRNA CTD PMID:20446767 tert-butyl hydroperoxide increases expression ISO RGD:1602898 6480464 tert-Butylhydroperoxide results in increased expression of PRDX6 protein CTD PMID:11295360 tert-butyl hydroperoxide affects response to substance ISO RGD:736132 6480464 PRDX6 protein affects the susceptibility to tert-Butylhydroperoxide CTD PMID:20627125 tert-butyl hydroperoxide increases response to substance ISO RGD:736132 6480464 PRDX6 gene mutant form results in increased susceptibility to tert-Butylhydroperoxide CTD PMID:12732627 tert-butyl hydroperoxide decreases response to substance ISO RGD:1602898 6480464 PRDX6 protein results in decreased susceptibility to tert-Butylhydroperoxide CTD PMID:14741336 testosterone affects expression ISO RGD:736132 6480464 Testosterone affects the expression of PRDX6 mRNA CTD PMID:17003280 tetrachloromethane multiple interactions ISO RGD:736132 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRDX6 mRNA] CTD PMID:25471833 tetrachloromethane decreases expression ISO RGD:736132 6480464 Carbon Tetrachloride results in decreased expression of PRDX6 mRNA CTD PMID:25471833 tetrachloromethane affects expression ISO RGD:736132 6480464 Carbon Tetrachloride affects the expression of PRDX6 mRNA CTD PMID:17484886 thapsigargin decreases expression ISO RGD:736132 6480464 Thapsigargin results in decreased expression of PRDX6 protein CTD PMID:24648495 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of PRDX6 mRNA CTD PMID:19483382 titanium dioxide increases expression ISO RGD:736132 6480464 titanium dioxide results in increased expression of PRDX6 mRNA CTD PMID:23557971 toluene affects expression EXP 6480464 Toluene affects the expression of PRDX6 mRNA CTD PMID:21827849 trichlopyr multiple interactions ISO RGD:736132 6480464 triclopyr inhibits the reaction [arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide results in increased expression of PRDX6 mRNA] CTD PMID:21318024 tunicamycin decreases expression ISO RGD:736132 6480464 Tunicamycin results in decreased expression of PRDX6 mRNA CTD PMID:17127020 valproic acid affects expression ISO RGD:736132 6480464 Valproic Acid affects the expression of PRDX6 mRNA CTD PMID:17292431 valproic acid increases expression ISO RGD:1602898 6480464 Valproic Acid results in increased expression of PRDX6 mRNA CTD PMID:23179753 valproic acid decreases expression ISO RGD:1602898 6480464 Valproic Acid results in decreased expression of PRDX6 mRNA CTD PMID:23179753 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of PRDX6 mRNA CTD PMID:19015723 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of PRDX6 mRNA CTD PMID:22570695 vorinostat increases expression ISO RGD:1602898 6480464 vorinostat results in increased expression of PRDX6 protein CTD PMID:20543569 zinc diethyldithiocarbamate increases expression EXP 6480464 Ditiocarb results in increased expression of PRDX6 protein CTD PMID:22874009
Gene-Chemical Interaction Annotations
