Casq1 (calsequestrin 1) - Rat Genome Database

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Gene: Casq1 (calsequestrin 1) Rattus norvegicus
Analyze
Symbol: Casq1
Name: calsequestrin 1
RGD ID: 1586677
Description: Enables calcium ion binding activity. Involved in several processes, including regulation of sequestering of calcium ion; response to denervation involved in regulation of muscle adaptation; and skeletal muscle tissue development. Located in I band; T-tubule; and terminal cisterna lumen. Colocalizes with Golgi apparatus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CASQ1 (calsequestrin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Aspartactin; calsequestrin 1 (fast-twitch, skeletal muscle); calsequestrin, skeletal muscle isoform; Calsequestrin-1; Laminin-binding protein; LOC686019; similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21384,670,648 - 84,680,339 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,670,649 - 84,680,339 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,173,972 - 87,183,660 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01388,574,232 - 88,583,921 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01385,758,977 - 85,768,666 (-)NCBIRnor_WKY
Rnor_6.01390,592,676 - 90,602,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,592,681 - 90,602,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,113,781 - 95,123,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,200,506 - 88,210,418 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1384,282,072 - 84,291,712 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians. Das SK, etal., Diabetes. 2004 Dec;53(12):3300-6.
2. Early effects of denervation on Ca(2+)-handling proteins in skeletal muscle. Donoghue P, etal., Int J Mol Med. 2004 Jun;13(6):767-72.
3. Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with type 2 diabetes in the old order Amish. Fu M, etal., Diabetes. 2004 Dec;53(12):3292-9.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Taurine supplementation increases skeletal muscle force production and protects muscle function during and after high-frequency in vitro stimulation. Goodman CA, etal., J Appl Physiol. 2009 Jul;107(1):144-54. Epub 2009 May 7.
6. Assembly of the sarcoplasmic reticulum. Synthesis of calsequestrin and the Ca2+ + Mg2+ -adenosine triphosphatase on membrane-bound polyribosomes. Greenway DC and MacLennan DH, Can J Biochem. 1978 Jun;56(6):452-6.
7. Type 2 diabetes susceptibility genes on chromosome 1q21-24. Hasstedt SJ, etal., Ann Hum Genet. 2008 Mar;72(Pt 2):163-9.
8. Calsequestrin expression and calcium binding is increased in streptozotocin-induced diabetic rat skeletal muscle though not in cardiac muscle. Howarth FC, etal., Pflugers Arch. 2002 May;444(1-2):52-8. Epub 2002 Feb 7.
9. Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy. Hunter RB, etal., Am J Physiol Cell Physiol. 2001 Oct;281(4):C1285-90.
10. Ultrastructural localization of calsequestrin in rat skeletal muscle by immunoferritin labeling of ultrathin frozen sections. Jorgensen AO, etal., J Cell Biol. 1983 Nov;97(5 Pt 1):1573-81.
11. Membrane associated Ca2+ buffers in the heart. Lee D and Michalak M, BMB Rep. 2010 Mar;43(3):151-7.
12. Calsequestrin content and SERCA determine normal and maximal Ca2+ storage levels in sarcoplasmic reticulum of fast- and slow-twitch fibres of rat. Murphy RM, etal., J Physiol. 2009 Jan 15;587(Pt 2):443-60. Epub 2008 Nov 24.
13. Restricted distribution of mRNAs encoding a sarcoplasmic reticulum or transverse tubule protein in skeletal myofibers. Nissinen M, etal., J Histochem Cytochem. 2005 Feb;53(2):217-27.
14. Site-directed mutagenesis and deletion of three phosphorylation sites of calsequestrin of skeletal muscle sarcoplasmic reticulum. Effects on intracellular targeting. Nori A, etal., Exp Cell Res. 2000 Oct 10;260(1):40-9.
15. Ca2+-regulatory muscle proteins in the alcohol-fed rat. Ohlendieck K, etal., Metabolism. 2003 Sep;52(9):1102-12.
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites. Sparso T, etal., Mol Genet Metab. 2007 Nov;92(3):278-82. Epub 2007 Aug 2.
19. Regulation of calcium binding proteins calreticulin and calsequestrin during differentiation in the myogenic cell line L6. Tharin S, etal., J Cell Physiol. 1996 Mar;166(3):547-60.
Additional References at PubMed
PMID:3417768   PMID:7945294   PMID:8042990   PMID:8889548   PMID:12419813   PMID:14651853   PMID:14728599   PMID:15057822   PMID:15489334   PMID:16600288   PMID:17627988   PMID:19237502  
PMID:20833797   PMID:22049211   PMID:22337878   PMID:25084748   PMID:27185316   PMID:28895244  


Genomics

Comparative Map Data
Casq1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21384,670,648 - 84,680,339 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,670,649 - 84,680,339 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,173,972 - 87,183,660 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01388,574,232 - 88,583,921 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01385,758,977 - 85,768,666 (-)NCBIRnor_WKY
Rnor_6.01390,592,676 - 90,602,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,592,681 - 90,602,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,113,781 - 95,123,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,200,506 - 88,210,418 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1384,282,072 - 84,291,712 (-)NCBICelera
Cytogenetic Map13q24NCBI
CASQ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,190,575 - 160,201,886 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1160,190,575 - 160,201,886 (+)EnsemblGRCh38hg38GRCh38
GRCh371160,160,365 - 160,171,676 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,426,989 - 158,438,300 (+)NCBINCBI36Build 36hg18NCBI36
Build 341156,973,468 - 156,984,752NCBI
Celera1133,229,049 - 133,240,436 (+)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,517,001 - 131,528,390 (+)NCBIHuRef
CHM1_11161,555,636 - 161,567,025 (+)NCBICHM1_1
T2T-CHM13v2.01159,327,652 - 159,338,962 (+)NCBIT2T-CHM13v2.0
Casq1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,037,461 - 172,047,462 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,037,461 - 172,047,435 (-)EnsemblGRCm39 Ensembl
GRCm381172,209,894 - 172,219,895 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,209,894 - 172,219,868 (-)EnsemblGRCm38mm10GRCm38
MGSCv371174,140,025 - 174,150,026 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,047,013 - 174,056,514 (-)NCBIMGSCv36mm8
Celera1175,065,863 - 175,075,868 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
Casq1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,967,678 - 11,978,836 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546811,967,678 - 11,978,836 (+)NCBIChiLan1.0ChiLan1.0
CASQ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11139,465,605 - 139,476,969 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1139,465,605 - 139,476,969 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01135,544,249 - 135,555,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CASQ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,012,060 - 22,020,430 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,011,060 - 22,020,383 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,084,775 - 22,093,156 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,128,163 - 22,136,607 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,128,165 - 22,134,332 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,032,897 - 22,041,272 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,429,210 - 22,437,626 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,838,952 - 22,847,496 (-)NCBIUU_Cfam_GSD_1.0
Casq1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,312,524 - 6,324,146 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740430,026 - 442,539 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936740430,367 - 442,468 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASQ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,276,757 - 90,288,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,276,752 - 90,288,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,218,225 - 98,228,665 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CASQ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,744,921 - 3,759,220 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl203,744,780 - 3,756,435 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660382,802,575 - 2,814,309 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casq1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,050,955 - 1,065,287 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247941,054,119 - 1,064,652 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Casq1
21 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:63
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000009344
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
RH133764  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,670,663 - 84,670,843 (+)MAPPERmRatBN7.2
Rnor_6.01390,592,692 - 90,592,871NCBIRnor6.0
Rnor_5.01395,113,797 - 95,113,976UniSTSRnor5.0
RGSC_v3.41388,200,522 - 88,200,701UniSTSRGSC3.4
Celera1384,282,088 - 84,282,267UniSTS
RH 3.4 Map13554.8UniSTS
Cytogenetic Map13q24UniSTS
G64925  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,681,014 - 84,681,174 (+)MAPPERmRatBN7.2
Rnor_6.01390,603,041 - 90,603,200NCBIRnor6.0
Rnor_5.01395,124,146 - 95,124,305UniSTSRnor5.0
RGSC_v3.41388,211,094 - 88,211,253UniSTSRGSC3.4
Celera1384,292,388 - 84,292,547UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 11 8
Medium 43 7 2 2 2 8 6 7
Low 3 28 17 17 17 74 27 35 4
Below cutoff 20 20 20

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009344   ⟹   ENSRNOP00000009344
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1384,670,649 - 84,680,339 (-)Ensembl
Rnor_6.0 Ensembl1390,592,681 - 90,602,365 (-)Ensembl
RefSeq Acc Id: NM_001159594   ⟹   NP_001153066
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21384,670,648 - 84,680,339 (-)NCBI
Rnor_6.01390,592,676 - 90,602,365 (-)NCBI
Rnor_5.01395,113,781 - 95,123,470 (-)NCBI
RGSC_v3.41388,200,506 - 88,210,418 (-)RGD
Celera1384,282,072 - 84,291,712 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001153066 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94693 (Get FASTA)   NCBI Sequence Viewer  
  P19633 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001153066   ⟸   NM_001159594
- Peptide Label: precursor
- UniProtKB: P19633 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009344   ⟸   ENSRNOT00000009344

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19633-F1-model_v2 AlphaFold P19633 1-406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699022
Promoter ID:EPDNEW_R9547
Type:multiple initiation site
Name:Casq1_1
Description:calsequestrin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01390,602,369 - 90,602,429EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586677 AgrOrtholog
BioCyc Gene G2FUF-17328 BioCyc
Ensembl Genes ENSRNOG00000006930 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000009344 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009344 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Calsequestrin UniProtKB/Swiss-Prot
  Calsequestrin_C UniProtKB/Swiss-Prot
  Calsequestrin_CS UniProtKB/Swiss-Prot
  Calsequestrin_middle_dom UniProtKB/Swiss-Prot
  Calsequestrin_N UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:686019 UniProtKB/Swiss-Prot
NCBI Gene 686019 ENTREZGENE
Pfam Calsequestrin UniProtKB/Swiss-Prot
PharmGKB CASQ1 RGD
PhenoGen Casq1 PhenoGen
PROSITE CALSEQUESTRIN_1 UniProtKB/Swiss-Prot
  CALSEQUESTRIN_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt CASQ1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Casq1  calsequestrin 1  Casq1  calsequestrin 1 (fast-twitch, skeletal muscle)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Casq1  calsequestrin 1 (fast-twitch, skeletal muscle)  Casq1  calsequestrin 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Casq1  calsequestrin 1  LOC679341  similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)  Data Merged 1643240 APPROVED
2008-03-05 Casq1  calsequestrin 1  LOC686019  similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC686019  similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679341  similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)      Symbol and Name status set to provisional 70820 PROVISIONAL