Fcer1g (Fc fragment of IgE receptor Ig) - Rat Genome Database

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Gene: Fcer1g (Fc fragment of IgE receptor Ig) Rattus norvegicus
Analyze
Symbol: Fcer1g
Name: Fc fragment of IgE receptor Ig
RGD ID: 2599
Description: Predicted to enable IgE receptor activity; IgG binding activity; and identical protein binding activity. Predicted to contribute to IgE binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; cell surface receptor signaling pathway; and defense response to other organism. Predicted to act upstream of or within several processes, including negative regulation of mast cell apoptotic process; positive regulation of cytokine production; and positive regulation of immune effector process. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be part of Fc-epsilon receptor I complex. Predicted to be active in external side of plasma membrane. Orthologous to human FCER1G (Fc fragment of IgE receptor Ig); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; asthma pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fc fragment of Ige high affinity I receptor for gamma polypeptide; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc receptor, IgE, high affinity I, gamma polypeptide; fc-epsilon RI-gamma; fceRI gamma; fcRgamma; gamma polypeptide; high affinity immunoglobulin epsilon receptor subunit gamma; igE Fc receptor subunit gamma; MGC188226
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,649,447 - 83,654,215 (-)NCBI
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,5-hexanedione  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenous acid  (ISO)
beclomethasone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (EXP)
citalopram  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclophosphamide  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
diuron  (EXP)
fenbuconazole  (ISO)
folic acid  (ISO)
ginkgolide B  (EXP)
glucose  (ISO)
ketotifen  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nilotinib  (ISO)
ochratoxin A  (EXP)
ozone  (EXP)
paracetamol  (ISO)
probucol  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (EXP)
tamibarotene  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antigen processing and presentation of exogenous peptide antigen via MHC class I  (IBA,ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IBA,ISO)
cell surface receptor signaling pathway  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO,ISS)
defense response to bacterium  (IBA,ISO)
Fc receptor mediated stimulatory signaling pathway  (IBA,ISO)
Fc-epsilon receptor signaling pathway  (ISO)
Fc-gamma receptor signaling pathway  (IBA,ISO)
immunoglobulin mediated immune response  (IBA,ISO)
innate immune response  (IBA,ISO)
integrin-mediated signaling pathway  (ISO)
interleukin-3-mediated signaling pathway  (ISO,ISS)
mast cell activation  (ISO)
negative regulation of mast cell apoptotic process  (ISO)
neutrophil activation involved in immune response  (IBA,ISO)
neutrophil chemotaxis  (IBA,ISO)
osteoclast differentiation  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of immune response  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-4 production  (ISO,ISS)
positive regulation of interleukin-6 production  (ISO)
positive regulation of mast cell cytokine production  (ISO)
positive regulation of mast cell degranulation  (ISO)
positive regulation of phagocytosis  (IBA,ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type I hypersensitivity  (ISO)
positive regulation of type IIa hypersensitivity  (ISO)
positive regulation of type III hypersensitivity  (ISO)
protein localization to plasma membrane  (ISO)
receptor internalization  (ISO,ISS)
regulation of immune response  (ISO)
regulation of platelet activation  (IBA,ISO)
serotonin secretion by platelet  (ISO)
signal transduction  (ISO)
T cell differentiation involved in immune response  (IBA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1535625   PMID:2527850   PMID:8976192   PMID:9000133   PMID:9171347   PMID:10229794   PMID:10395649   PMID:11237803   PMID:11420040   PMID:11901193   PMID:11911823   PMID:11911824  
PMID:12192036   PMID:12477932   PMID:14643301   PMID:14764707   PMID:14967045   PMID:15184345   PMID:15339843   PMID:16735691   PMID:17086186   PMID:17365510   PMID:17543387   PMID:19098920  
PMID:19356729   PMID:21841309   PMID:22964482   PMID:23395392   PMID:23602766   PMID:28033741   PMID:28393919  


Genomics

Candidate Gene Status
Fcer1g is a candidate Gene for QTL Glom27
Comparative Map Data
Fcer1g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,649,447 - 83,654,215 (-)NCBI
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
FCER1G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1161,215,234 - 161,220,699 (+)EnsemblGRCh38hg38GRCh38
GRCh381161,215,295 - 161,219,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,185,085 - 161,189,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,451,711 - 159,455,662 (+)NCBINCBI36hg18NCBI36
Build 341157,998,159 - 158,002,111NCBI
Celera1134,252,239 - 134,256,190 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,542,035 - 132,545,988 (+)NCBIHuRef
CHM1_11162,581,340 - 162,585,295 (+)NCBICHM1_1
Fcer1g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,057,141 - 171,061,918 (-)NCBIGRCm39mm39
GRCm39 Ensembl1171,057,141 - 171,061,934 (-)Ensembl
GRCm381171,229,572 - 171,234,349 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,229,572 - 171,234,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,159,703 - 173,164,480 (-)NCBIGRCm37mm9NCBIm37
MGSCv361173,066,247 - 173,071,024 (-)NCBImm8
Celera1173,677,711 - 173,690,567 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.23NCBI
Fcer1g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,971,931 - 12,975,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,971,931 - 12,975,206 (+)NCBIChiLan1.0ChiLan1.0
FCER1G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11140,539,555 - 140,543,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,539,555 - 140,544,810 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBIMhudiblu_PPA_v0panPan3
FCER1G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,267,841 - 21,271,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,268,001 - 21,270,940 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,342,857 - 21,345,796 (-)NCBI
ROS_Cfam_1.03821,385,844 - 21,388,784 (-)NCBI
UNSW_CanFamBas_1.03821,688,132 - 21,691,072 (-)NCBI
UU_Cfam_GSD_1.03822,097,280 - 22,100,221 (-)NCBI
Fcer1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,305,613 - 7,309,317 (+)NCBI
SpeTri2.0NW_004936903514,278 - 517,975 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCER1G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,242,459 - 89,247,065 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,099,149 - 97,103,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FCER1G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,763,412 - 2,767,774 (-)NCBI
ChlSab1.1 Ensembl202,763,417 - 2,767,248 (-)Ensembl
Vero_WHO_p1.0NW_0236660381,811,779 - 1,815,687 (-)NCBI
Fcer1g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624794168,564 - 172,433 (-)NCBI

Position Markers
RH129161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,649,476 - 83,649,659 (+)MAPPER
Rnor_6.01389,601,924 - 89,602,106NCBIRnor6.0
Rnor_5.01394,228,789 - 94,228,971UniSTSRnor5.0
RGSC_v3.41387,119,494 - 87,119,676UniSTSRGSC3.4
Celera1383,280,660 - 83,280,842UniSTS
RH 3.4 Map13551.5UniSTS
Cytogenetic Map13q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135108098996080989Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135156924896569248Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)135157782490675199Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1357903612102903612Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1362975663107975663Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136500824591629354Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1366971778111971778Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1371230858114033958Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1371230858114033958Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1372583716114033958Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137456837892916783Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137456837892916783Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137456837892916783Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)777694986114033958Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1379567081103613733Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)138040355991629354Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1380403559108770687Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1386833393114033958Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:43
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000029179
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 25 48 36 19 36 2 62 34 31 11
Low 18 9 5 5 8 9 12 1 10 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029179   ⟹   ENSRNOP00000036716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)Ensembl
RefSeq Acc Id: NM_001131001   ⟹   NP_001124473
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,649,447 - 83,653,880 (-)NCBI
Rnor_6.01389,601,894 - 89,606,326 (-)NCBI
Rnor_5.01394,228,759 - 94,233,459 (-)NCBI
RGSC_v3.41387,119,464 - 87,123,902 (-)RGD
Celera1383,280,630 - 83,285,062 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090389   ⟹   XP_038946317
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,649,447 - 83,654,161 (-)NCBI
RefSeq Acc Id: XM_039090390   ⟹   XP_038946318
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,649,447 - 83,654,215 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001124473 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946317 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946318 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI60864 (Get FASTA)   NCBI Sequence Viewer  
  EDL94613 (Get FASTA)   NCBI Sequence Viewer  
  P20411 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001124473   ⟸   NM_001131001
- Peptide Label: precursor
- UniProtKB: P20411 (UniProtKB/Swiss-Prot),   B1H251 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000036716   ⟸   ENSRNOT00000029179
RefSeq Acc Id: XP_038946318   ⟸   XM_039090390
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946317   ⟸   XM_039090389
- Peptide Label: isoform X1
Protein Domains
ITAM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698997
Promoter ID:EPDNEW_R9522
Type:initiation region
Name:Fcer1g_1
Description:Fc fragment of IgE receptor Ig
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,606,303 - 89,606,363EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2599 AgrOrtholog
Ensembl Genes ENSRNOG00000024159 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000036716 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000029179 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro CD3_zeta/IgE_Fc_rcpt_gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FCER1G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phos_immunorcpt_sig_ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25441 ENTREZGENE
PANTHER PTHR16803 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCR_zetazeta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fcer1g PhenoGen
PROSITE ITAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1H251 ENTREZGENE, UniProtKB/TrEMBL
  FCERG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Fcer1g  Fc fragment of IgE receptor Ig  Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  LOC498279  similar to NADH dehydrogenase (ubiquinone) Fe-S protein 2  Data Merged 1643240 APPROVED
2008-09-25 Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  Fcer1g  Fc receptor, IgE, high affinity I, gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC498279  similar to NADH dehydrogenase (ubiquinone) Fe-S protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Fcer1g  Fc fragment of Ige, high affinity I, receptor for gamma polypeptide      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction tetrameric complex composed of one alpha subunit, one beta subunit and a dimer of disulphide-linked gamma subunits 728449