Desi2 (desumoylating isopeptidase 2) - Rat Genome Database

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Gene: Desi2 (desumoylating isopeptidase 2) Rattus norvegicus
Analyze
Symbol: Desi2
Name: desumoylating isopeptidase 2
RGD ID: 1359392
Description: Predicted to enable K48-linked deubiquitinase activity; K63-linked deubiquitinase activity; and cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Orthologous to human DESI2 (desumoylating isopeptidase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CGI-146; DeSI-2; deubiquitinase DESI2; Fam152a; family with sequence similarity 152, member A; PNAS-4; PPPDE peptidase domain containing 1; PPPDE peptidase domain-containing protein 1; Pppde1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,493,765 - 92,543,307 (+)NCBIGRCr8
mRatBN7.21389,961,767 - 90,011,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1392,467,195 - 92,510,053 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,867,337 - 93,910,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,048,646 - 91,091,598 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,111,800 - 96,156,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013100,553,747 - 100,599,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41393,895,171 - 93,903,458 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11394,084,106 - 94,092,392 (+)NCBI
Celera1389,520,725 - 89,563,808 (+)NCBICelera
Cytogenetic Map13q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21553223   PMID:22370726   PMID:28483520   PMID:33794264  


Genomics

Comparative Map Data
Desi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,493,765 - 92,543,307 (+)NCBIGRCr8
mRatBN7.21389,961,767 - 90,011,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1392,467,195 - 92,510,053 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,867,337 - 93,910,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,048,646 - 91,091,598 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,111,800 - 96,156,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013100,553,747 - 100,599,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41393,895,171 - 93,903,458 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11394,084,106 - 94,092,392 (+)NCBI
Celera1389,520,725 - 89,563,808 (+)NCBICelera
Cytogenetic Map13q25NCBI
DESI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381244,653,126 - 244,709,033 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1244,653,103 - 244,709,033 (+)EnsemblGRCh38hg38GRCh38
GRCh371244,816,428 - 244,872,335 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,882,975 - 242,938,958 (+)NCBINCBI36Build 36hg18NCBI36
Celera1218,106,243 - 218,162,211 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1215,199,549 - 215,255,506 (+)NCBIHuRef
CHM1_11246,088,656 - 246,144,628 (+)NCBICHM1_1
T2T-CHM13v2.01244,069,385 - 244,125,271 (+)NCBIT2T-CHM13v2.0
Desi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,014,983 - 178,080,164 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,014,983 - 178,084,867 (+)EnsemblGRCm39 Ensembl
GRCm381178,187,417 - 178,252,598 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,187,417 - 178,257,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371180,117,548 - 180,182,729 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361180,024,385 - 180,089,269 (+)NCBIMGSCv36mm8
Celera1185,247,627 - 185,312,483 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map182.93NCBI
Desi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554067,880,648 - 7,894,629 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554067,881,815 - 7,894,690 (+)NCBIChiLan1.0ChiLan1.0
DESI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214,448,197 - 4,507,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114,670,620 - 4,726,951 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01220,246,390 - 220,302,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11225,626,913 - 225,682,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1225,626,913 - 225,682,772 (+)Ensemblpanpan1.1panPan2
DESI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1735,688,519 - 35,734,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl735,687,888 - 35,731,186 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha735,161,634 - 35,208,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0735,516,735 - 35,563,360 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl735,516,660 - 35,563,350 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1735,352,288 - 35,398,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0735,367,194 - 35,413,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0735,632,821 - 35,679,443 (+)NCBIUU_Cfam_GSD_1.0
Desi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934448,566,633 - 48,617,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365266,129,500 - 6,180,668 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365266,130,714 - 6,180,546 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DESI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1017,365,689 - 17,416,635 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11017,365,649 - 17,416,642 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21019,696,102 - 19,747,165 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DESI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12581,670,135 - 81,733,696 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2581,670,170 - 81,733,812 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605583,892,549 - 83,956,201 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Desi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477114,879,277 - 14,927,002 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477114,879,275 - 14,927,352 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Desi2
279 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:213
Count of miRNA genes:149
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000005967
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
RH133177  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,004,865 - 90,005,075 (+)MAPPERmRatBN7.2
Rnor_6.01396,154,763 - 96,154,972NCBIRnor6.0
Rnor_5.013100,597,496 - 100,597,705UniSTSRnor5.0
RGSC_v3.41393,903,532 - 93,903,741UniSTSRGSC3.4
Celera1389,563,882 - 89,564,091UniSTS
RH 3.4 Map13607.5UniSTS
Cytogenetic Map13q25UniSTS
RH144438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,004,372 - 90,004,497 (+)MAPPERmRatBN7.2
Rnor_6.01396,154,270 - 96,154,394NCBIRnor6.0
Rnor_5.013100,597,003 - 100,597,127UniSTSRnor5.0
RGSC_v3.41393,903,039 - 93,903,163UniSTSRGSC3.4
Celera1389,563,389 - 89,563,513UniSTS
RH 3.4 Map13608.5UniSTS
Cytogenetic Map13q25UniSTS
BI293545  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21389,977,262 - 89,977,412 (+)MAPPERmRatBN7.2
Rnor_6.01396,127,116 - 96,127,265NCBIRnor6.0
Rnor_5.013100,570,275 - 100,570,424UniSTSRnor5.0
Celera1389,536,259 - 89,536,408UniSTS
RH 3.4 Map13605.9UniSTS
Cytogenetic Map13q25UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 50 35 19 35 4 6 67 32 40 11 4
Low 17 7 6 6 4 5 7 3 1 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000005967   ⟹   ENSRNOP00000005967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,961,934 - 90,004,788 (+)Ensembl
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087964   ⟹   ENSRNOP00000069021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)Ensembl
Rnor_6.0 Ensembl1396,122,120 - 96,153,823 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096311   ⟹   ENSRNOP00000090662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,991,647 - 90,004,805 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098343   ⟹   ENSRNOP00000091146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,971,669 - 90,004,805 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108395   ⟹   ENSRNOP00000091139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,990,942 - 90,004,805 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115830   ⟹   ENSRNOP00000090046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,962,414 - 90,004,805 (+)Ensembl
RefSeq Acc Id: NM_001013873   ⟹   NP_001013895
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,989 - 92,536,844 (+)NCBI
mRatBN7.21389,961,934 - 90,004,792 (+)NCBI
Rnor_6.01396,111,800 - 96,154,689 (+)NCBI
Rnor_5.013100,553,747 - 100,599,426 (+)NCBI
RGSC_v3.41393,895,171 - 93,903,458 (+)RGD
Celera1389,520,725 - 89,563,808 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250317   ⟹   XP_006250379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,948 - 92,543,307 (+)NCBI
mRatBN7.21389,961,812 - 90,011,255 (+)NCBI
Rnor_6.01396,111,960 - 96,156,693 (+)NCBI
Rnor_5.013100,553,747 - 100,599,426 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598724   ⟹   XP_017454213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,948 - 92,543,307 (+)NCBI
mRatBN7.21389,962,245 - 90,011,255 (+)NCBI
Rnor_6.01396,111,960 - 96,156,693 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598725   ⟹   XP_017454214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,494,498 - 92,543,307 (+)NCBI
mRatBN7.21389,962,854 - 90,011,255 (+)NCBI
Rnor_6.01396,112,259 - 96,156,693 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090529   ⟹   XP_038946457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,494,500 - 92,543,307 (+)NCBI
mRatBN7.21389,962,854 - 90,011,255 (+)NCBI
RefSeq Acc Id: XM_039090530   ⟹   XP_038946458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,765 - 92,543,307 (+)NCBI
mRatBN7.21389,961,767 - 90,011,255 (+)NCBI
RefSeq Acc Id: XM_039090532   ⟹   XP_038946460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,766 - 92,532,185 (+)NCBI
mRatBN7.21389,961,772 - 90,003,485 (+)NCBI
RefSeq Acc Id: XM_063272134   ⟹   XP_063128204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,411 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272135   ⟹   XP_063128205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,411 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272136   ⟹   XP_063128206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,495,233 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272137   ⟹   XP_063128207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,401 - 92,543,307 (+)NCBI
RefSeq Acc Id: NP_001013895   ⟸   NM_001013873
- UniProtKB: Q5XIT6 (UniProtKB/Swiss-Prot),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250379   ⟸   XM_006250317
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AD20 (UniProtKB/TrEMBL),   A0A8I6AER3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454213   ⟸   XM_017598724
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454214   ⟸   XM_017598725
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069021   ⟸   ENSRNOT00000087964
RefSeq Acc Id: ENSRNOP00000005967   ⟸   ENSRNOT00000005967
RefSeq Acc Id: XP_038946458   ⟸   XM_039090530
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038946460   ⟸   XM_039090532
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038946457   ⟸   XM_039090529
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GJD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090046   ⟸   ENSRNOT00000115830
RefSeq Acc Id: ENSRNOP00000090662   ⟸   ENSRNOT00000096311
RefSeq Acc Id: ENSRNOP00000091146   ⟸   ENSRNOT00000098343
RefSeq Acc Id: ENSRNOP00000091139   ⟸   ENSRNOT00000108395
RefSeq Acc Id: XP_063128206   ⟸   XM_063272136
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128207   ⟸   XM_063272137
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063128204   ⟸   XM_063272134
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128205   ⟸   XM_063272135
- Peptide Label: isoform X1
Protein Domains
PPPDE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIT6-F1-model_v2 AlphaFold Q5XIT6 1-194 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699046
Promoter ID:EPDNEW_R9571
Type:initiation region
Name:Desi2_1
Description:desumoylating isopeptidase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01396,111,976 - 96,112,036EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359392 AgrOrtholog
BioCyc Gene G2FUF-17177 BioCyc
Ensembl Genes ENSRNOG00000004524 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055023882 UniProtKB/Swiss-Prot
  ENSRNOG00060006507 UniProtKB/Swiss-Prot
  ENSRNOG00065025041 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005967 ENTREZGENE
  ENSRNOT00000005967.8 UniProtKB/Swiss-Prot
  ENSRNOT00000087964.2 UniProtKB/TrEMBL
  ENSRNOT00000096311.1 UniProtKB/TrEMBL
  ENSRNOT00000098343.1 UniProtKB/TrEMBL
  ENSRNOT00000108395.1 UniProtKB/TrEMBL
  ENSRNOT00000115830.1 UniProtKB/TrEMBL
  ENSRNOT00055041057 UniProtKB/Swiss-Prot
  ENSRNOT00060010728 UniProtKB/Swiss-Prot
  ENSRNOT00065043240 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.1720.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131107 IMAGE-MGC_LOAD
InterPro PPPDE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPPDE_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:289277 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94230 IMAGE-MGC_LOAD
NCBI Gene 289277 ENTREZGENE
PANTHER DEUBIQUITINASE DESI2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12378 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_C97 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Desi2 PhenoGen
PROSITE PPPDE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004524 RatGTEx
  ENSRNOG00055023882 RatGTEx
  ENSRNOG00060006507 RatGTEx
  ENSRNOG00065025041 RatGTEx
SMART DUF862 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUA0_RAT UniProtKB/TrEMBL
  A0A8I6AD20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AER3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJD8 ENTREZGENE, UniProtKB/TrEMBL
  DESI2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Desi2  desumoylating isopeptidase 2  Pppde1  PPPDE peptidase domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-23 Pppde1  PPPDE peptidase domain containing 1  Fam152a  family with sequence similarity 152, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Fam152a  family with sequence similarity 152, member A  PNAS-4  CGI-146 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 PNAS-4  CGI-146 protein      Symbol and Name status set to provisional 70820 PROVISIONAL