Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ovarian Neoplasms | | ISO | DESI2 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:21667029 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ovarian Neoplasms | | ISO | DESI2 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:21667029 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
4. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
Desi2 (Rattus norvegicus - Norway rat) |
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DESI2 (Homo sapiens - human) |
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Desi2 (Mus musculus - house mouse) |
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Desi2 (Chinchilla lanigera - long-tailed chinchilla) |
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DESI2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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DESI2 (Canis lupus familiaris - dog) |
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Desi2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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DESI2 (Sus scrofa - pig) |
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DESI2 (Chlorocebus sabaeus - green monkey) |
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Desi2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Desi2
279 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH133177 |
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RH144438 |
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BI293545 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 26 | 50 | 35 | 19 | 35 | 4 | 6 | 67 | 32 | 40 | 11 | 4 |
Low | 17 | 7 | 6 | 6 | 4 | 5 | 7 | 3 | 1 | 4 | |||
Below cutoff |
RefSeq Transcripts | NM_001013873 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006250317 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598723 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598724 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598725 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090529 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090530 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090532 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272134 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272135 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272136 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272137 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | BC083584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473985 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ226068 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000005967 ⟹ ENSRNOP00000005967 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000087964 ⟹ ENSRNOP00000069021 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096311 ⟹ ENSRNOP00000090662 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000098343 ⟹ ENSRNOP00000091146 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000108395 ⟹ ENSRNOP00000091139 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000115830 ⟹ ENSRNOP00000090046 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001013873 ⟹ NP_001013895 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250317 ⟹ XP_006250379 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017598724 ⟹ XP_017454213 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017598725 ⟹ XP_017454214 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039090529 ⟹ XP_038946457 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039090530 ⟹ XP_038946458 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039090532 ⟹ XP_038946460 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063272134 ⟹ XP_063128204 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272135 ⟹ XP_063128205 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272136 ⟹ XP_063128206 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272137 ⟹ XP_063128207 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001013895 | (Get FASTA) | NCBI Sequence Viewer |
XP_006250379 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017454213 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017454214 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946457 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946458 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946460 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128204 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128205 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128206 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128207 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH83584 | (Get FASTA) | NCBI Sequence Viewer |
EDL94795 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000005967 | ||
ENSRNOP00000005967.5 | |||
ENSRNOP00000069021.2 | |||
ENSRNOP00000090046 | |||
ENSRNOP00000090046.1 | |||
ENSRNOP00000090662.1 | |||
ENSRNOP00000091139.1 | |||
ENSRNOP00000091146 | |||
ENSRNOP00000091146.1 | |||
ENSRNOP00055033387 | |||
ENSRNOP00060007951 | |||
ENSRNOP00065035436 | |||
GenBank Protein | Q5XIT6 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001013895 ⟸ NM_001013873 |
- UniProtKB: | Q5XIT6 (UniProtKB/Swiss-Prot), A0A8I6GJD8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006250379 ⟸ XM_006250317 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8I6AD20 (UniProtKB/TrEMBL), A0A8I6AER3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017454213 ⟸ XM_017598724 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6AF15 (UniProtKB/TrEMBL), A0A8I6GJD8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017454214 ⟸ XM_017598725 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6AF15 (UniProtKB/TrEMBL), A0A8I6GJD8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000069021 ⟸ ENSRNOT00000087964 |
RefSeq Acc Id: | ENSRNOP00000005967 ⟸ ENSRNOT00000005967 |
RefSeq Acc Id: | XP_038946458 ⟸ XM_039090530 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_038946460 ⟸ XM_039090532 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_038946457 ⟸ XM_039090529 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6GJD8 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000090046 ⟸ ENSRNOT00000115830 |
RefSeq Acc Id: | ENSRNOP00000090662 ⟸ ENSRNOT00000096311 |
RefSeq Acc Id: | ENSRNOP00000091146 ⟸ ENSRNOT00000098343 |
RefSeq Acc Id: | ENSRNOP00000091139 ⟸ ENSRNOT00000108395 |
RefSeq Acc Id: | XP_063128206 ⟸ XM_063272136 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063128207 ⟸ XM_063272137 |
- Peptide Label: | isoform X5 |
RefSeq Acc Id: | XP_063128204 ⟸ XM_063272134 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128205 ⟸ XM_063272135 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q5XIT6-F1-model_v2 | AlphaFold | Q5XIT6 | 1-194 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699046 | ||||||||
Promoter ID: | EPDNEW_R9571 | ||||||||
Type: | initiation region | ||||||||
Name: | Desi2_1 | ||||||||
Description: | desumoylating isopeptidase 2 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1359392 | AgrOrtholog |
BioCyc Gene | G2FUF-17177 | BioCyc |
Ensembl Genes | ENSRNOG00000004524 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00055023882 | UniProtKB/Swiss-Prot | |
ENSRNOG00060006507 | UniProtKB/Swiss-Prot | |
ENSRNOG00065025041 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000005967 | ENTREZGENE |
ENSRNOT00000005967.8 | UniProtKB/Swiss-Prot | |
ENSRNOT00000087964.2 | UniProtKB/TrEMBL | |
ENSRNOT00000096311.1 | UniProtKB/TrEMBL | |
ENSRNOT00000098343.1 | UniProtKB/TrEMBL | |
ENSRNOT00000108395.1 | UniProtKB/TrEMBL | |
ENSRNOT00000115830.1 | UniProtKB/TrEMBL | |
ENSRNOT00055041057 | UniProtKB/Swiss-Prot | |
ENSRNOT00060010728 | UniProtKB/Swiss-Prot | |
ENSRNOT00065043240 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 3.90.1720.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7131107 | IMAGE-MGC_LOAD |
InterPro | PPPDE_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PPPDE_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:289277 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:94230 | IMAGE-MGC_LOAD |
NCBI Gene | 289277 | ENTREZGENE |
PANTHER | DEUBIQUITINASE DESI2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR12378 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Peptidase_C97 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Desi2 | PhenoGen |
PROSITE | PPPDE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000004524 | RatGTEx |
ENSRNOG00055023882 | RatGTEx | |
ENSRNOG00060006507 | RatGTEx | |
ENSRNOG00065025041 | RatGTEx | |
SMART | DUF862 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A0G2JUA0_RAT | UniProtKB/TrEMBL |
A0A8I6AD20 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6AER3 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6AF15 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6GJD8 | ENTREZGENE, UniProtKB/TrEMBL | |
DESI2_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2012-10-10 | Desi2 | desumoylating isopeptidase 2 | Pppde1 | PPPDE peptidase domain containing 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2009-02-23 | Pppde1 | PPPDE peptidase domain containing 1 | Fam152a | family with sequence similarity 152, member A | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-06 | Fam152a | family with sequence similarity 152, member A | PNAS-4 | CGI-146 protein | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-07-29 | PNAS-4 | CGI-146 protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |