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Gene: Cdc73 (cell division cycle 73) Rattus norvegicus
Symbol: Cdc73
Name: cell division cycle 73
Description: Predicted to have RNA polymerase II complex binding activity. Predicted to be involved in several processes, including histone ubiquitination; mRNA 3'-end processing; and regulation of RNA metabolic process. Predicted to localize to the Cdc73/Paf1 complex and cytosol. Human ortholog(s) of this gene implicated in hyperparathyroidism and parathyroid carcinoma. Orthologous to human CDC73 (cell division cycle 73); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
Also known as: cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); cell division cycle protein 73 homolog; Hrpt2; hyperparathyroidism 2 (with jaw tumor); hyperparathyroidism 2 protein homolog; LOC304832; parafibromin
Homo sapiens (human) : CDC73 (cell division cycle 73)  HGNC  Alliance
Mus musculus (house mouse) : Cdc73 (cell division cycle 73, Paf1/RNA polymerase II complex component)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc73 (cell division cycle 73)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC73 (cell division cycle 73)
Canis lupus familiaris (dog) : CDC73 (cell division cycle 73)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc73 (cell division cycle 73)
Sus scrofa (pig) : CDC73 (cell division cycle 73)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01360,403,771 - 60,496,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,403,771 - 60,496,511 (-)Ensembl
Rnor_5.01365,392,579 - 65,485,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,441,674 - 57,534,385 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,455,753 - 57,548,465 (-)NCBI
Celera1355,444,707 - 55,537,113 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Cdc73
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311766
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.