 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
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InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Dennd1b (Rattus norvegicus - Norway rat) |
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| DENND1B (Homo sapiens - human) |
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| Dennd1b (Mus musculus - house mouse) |
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| Dennd1b (Chinchilla lanigera - long-tailed chinchilla) |
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| DENND1B (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DENND1B (Canis lupus familiaris - dog) |
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| Dennd1b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DENND1B (Sus scrofa - pig) |
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Position Markers| D13Rat136 |
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| RH131630 |
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| fa07h10.s1 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 12 | 8 | 8 | 4 | 4 | 2 | 8 | 6 | 8 | 11 | 8 | 18 | 8 | 8 | ||
| Low | 10 | 34 | 15 | 11 | 1 | 3 | 26 | 19 | 3 | 33 | 17 | |||||
| Below cutoff | 1 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | XM_003751244 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_003751245 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_003752643 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_003752644 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008762373 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008769580 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07021080 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07021081 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07021082 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07021083 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07021084 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07021085 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075370 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075371 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075372 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075373 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075374 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075375 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075376 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075377 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075378 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075379 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | XM_003751244 ⟹ XP_003751292 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GGCCGACCGCCGCTCGTATCAGCGCGTCCCGGACGGCGTGCGGGCGTGCGGGCGCGGGGCGACGhide sequence |
| RefSeq Acc Id: | XM_003751245 ⟹ XP_003751293 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GGCCGACCGCCGCTCGTATCAGCGCGTCCCGGACGGCGTGCGGGCGTGCGGGCGCGGGGCGACGhide sequence |
| RefSeq Acc Id: | XM_003752643 ⟹ XP_003752691 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GCGTGCGGGCGTCCGGGCGCGGGGCGACGGCGGCCCCGCAGCGACATGTGACCATGGACCGCAGhide sequence |
| RefSeq Acc Id: | XM_003752644 ⟹ XP_003752692 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GCGTGCGGGCGTCCGGGCGCGGGGCGACGGCGGCCCCGCAGCGACATGTGACCATGGACCGCAGhide sequence |
| RefSeq Acc Id: | XM_008762373 ⟹ XP_008760595 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GCGTGCGGGCGTCCGGGCGCGGGGCGACGGCGGCCCCGCAGCGACATGTGACCATGGACCGCAGhide sequence |
| RefSeq Acc Id: | XM_008769580 ⟹ XP_008767802 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGCCGACCGCCGCTCGTATCAGCGCGTCCCGGACGGCGTGCGGGCGTGCGGGCGCGGGGCGACGhide sequence |
Protein Sequences| Protein RefSeqs | XP_003751292 | (Get FASTA) | NCBI Sequence Viewer |
| XP_003751293 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_003752691 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_003752692 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008760595 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008767802 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | EDM09626 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | XP_003751293 ⟸ XM_003751245 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MDRRTRENPERTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEVLQSVPRFCFPFDVERVSQNQhide sequence |
| RefSeq Acc Id: | XP_003751292 ⟸ XM_003751244 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3Z8F6 (UniProtKB/TrEMBL) |
| - Sequence: |
MDRRTRENPERTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEVLQSVPRFCFPFDVERVSQNQhide sequence |
| RefSeq Acc Id: | XP_003752692 ⟸ XM_003752644 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MDRRTRENPERTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEVLQSVPRFCFPFDVERVSQNQhide sequence |
| RefSeq Acc Id: | XP_003752691 ⟸ XM_003752643 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3Z8F6 (UniProtKB/TrEMBL) |
| - Sequence: |
MDRRTRENPERTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEVLQSVPRFCFPFDVERVSQNQhide sequence |
| RefSeq Acc Id: | XP_008760595 ⟸ XM_008762373 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MPLKMKILWYCGNSQRTLEISYLPWFEVYYKLLNTLADYLAKELEDDLNETLKSLYSHPVPKANhide sequence |
| RefSeq Acc Id: | XP_008767802 ⟸ XM_008769580 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MPLKMKILWYCGNSQRTLEISYLPWFEVYYKLLNTLADYLAKELEDDLNETLKSLYSHPVPKANhide sequence |
TranscriptomePromoters| RGD ID: | 13698862 | |||||||||
| Promoter ID: | EPDNEW_R9386 | |||||||||
| Type: | initiation region | |||||||||
| Name: | Dennd1b_1 | |||||||||
| Description: | DENN domain containing 1B | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 13 | 61231373 | 61231374 | C | A | snv | GK/Ox (KNAW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1308441 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000011063 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000037059 | UniProtKB/TrEMBL |
| ENSRNOP00000043081 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOP00000065780 | UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000035129 | UniProtKB/TrEMBL |
| ENSRNOT00000043907 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOT00000075072 | UniProtKB/TrEMBL | |
| InterPro | dDENN_dom | UniProtKB/TrEMBL |
| DENN_dom | UniProtKB/TrEMBL | |
| DENND1A/B/C | UniProtKB/TrEMBL | |
| Tripartite_DENN | UniProtKB/TrEMBL | |
| uDENN_dom | UniProtKB/TrEMBL | |
| KEGG Report | rno:289051 | UniProtKB/TrEMBL |
| NCBI Gene | 289051 | ENTREZGENE |
| PANTHER | PTHR13196 | UniProtKB/TrEMBL |
| Pfam | dDENN | UniProtKB/TrEMBL |
| DENN | UniProtKB/TrEMBL | |
| uDENN | UniProtKB/TrEMBL | |
| PhenoGen | Dennd1b | PhenoGen |
| PROSITE | DENN | UniProtKB/TrEMBL |
| SMART | dDENN | UniProtKB/TrEMBL |
| DENN | UniProtKB/TrEMBL | |
| uDENN | UniProtKB/TrEMBL | |
| UniProt | D3Z8F6 | ENTREZGENE, UniProtKB/TrEMBL |
| F1M3B0_RAT | UniProtKB/TrEMBL | |
| M0R8I4_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2016-02-17 | Dennd1b | DENN domain containing 1B | Dennd1b | DENN/MADD domain containing 1B | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-03-04 | Dennd1b | DENN/MADD domain containing 1B | Fam31b_predicted | family with sequence similarity 31, member B (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-01-12 | Fam31b_predicted | family with sequence similarity 31, member B (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Dennd1b | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1308441 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-08-20 |
| Status: | ACTIVE |
