Dhx9 (DExH-box helicase 9) - Rat Genome Database

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Gene: Dhx9 (DExH-box helicase 9) Rattus norvegicus
Analyze
Symbol: Dhx9
Name: DExH-box helicase 9
RGD ID: 1308548
Description: Predicted to enable several functions, including helicase activity; nucleic acid binding activity; and ribonucleoprotein complex binding activity. Predicted to be involved in several processes, including DNA geometric change; regulation of defense response; and regulation of gene expression. Predicted to act upstream of or within cellular response to heat and circadian rhythm. Predicted to be located in several cellular components, including cytoskeleton; nuclear lumen; and ribonucleoprotein granule. Predicted to be part of several cellular components, including CRD-mediated mRNA stability complex; RISC complex; and RISC-loading complex. Predicted to be active in nucleolus. Orthologous to human DHX9 (DExH-box helicase 9); PARTICIPATES IN aldosterone signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-dependent RNA helicase A; DEAH (Asp-Glu-Ala-His) box helicase 9; DEAH (Asp-Glu-Ala-His) box polypeptide 9; DEAH-box helicase 9; LOC304859
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,602,322 - 65,639,098 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1365,602,323 - 65,639,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1368,205,589 - 68,242,212 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01369,494,069 - 69,530,666 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01366,745,395 - 66,781,953 (-)NCBIRnor_WKY
Rnor_6.01370,885,503 - 70,922,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01375,851,156 - 75,887,898 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,471,256 - 68,507,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11368,485,388 - 68,522,077 (-)NCBI
Celera1365,505,727 - 65,542,475 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3',5'-cyclic UMP  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-azacytidine  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chloromethylisothiazolinone  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
fulvestrant  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
metformin  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
phenytoin  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
succimer  (ISO)
tert-butyl hydroperoxide  (ISO)
Testosterone propionate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alternative mRNA splicing, via spliceosome  (ISO)
biological_process  (ND)
cellular response to exogenous dsRNA  (ISO)
cellular response to heat  (ISO)
cellular response to tumor necrosis factor  (ISO)
circadian rhythm  (ISO)
CRD-mediated mRNA stabilization  (ISO)
DNA duplex unwinding  (ISO)
DNA-templated transcription termination  (IEA)
DNA-templated viral transcription  (ISO)
G-quadruplex DNA unwinding  (ISO)
global gene silencing by mRNA cleavage  (ISO)
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (ISO)
positive regulation of cytoplasmic translation  (ISO)
positive regulation of DNA repair  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of innate immune response  (ISO)
positive regulation of interferon-alpha production  (ISO)
positive regulation of interferon-beta production  (ISO)
positive regulation of interleukin-18 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of miRNA-mediated gene silencing  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of polysome binding  (ISO)
positive regulation of response to cytokine stimulus  (ISO)
positive regulation of RNA export from nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of viral transcription  (ISO)
positive regulation of viral translation  (ISO)
protein localization to cytoplasmic stress granule  (ISO)
protein-containing complex assembly  (ISO)
pyroptosis  (ISO)
regulation of cytoplasmic translation  (ISO)
regulation of defense response to virus by host  (ISO)
regulation of mRNA processing  (IBA,ISO)
regulation of transcription by RNA polymerase II  (ISO)
RISC complex assembly  (ISO)
RNA secondary structure unwinding  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:1537828   PMID:9111062   PMID:9162007   PMID:9323138   PMID:9662397   PMID:10198287   PMID:10207077   PMID:11038348   PMID:11096080   PMID:11402034   PMID:11416126   PMID:11687588  
PMID:12711669   PMID:14704337   PMID:14729462   PMID:15121898   PMID:15355351   PMID:16210410   PMID:16375861   PMID:16680162   PMID:17289661   PMID:17303075   PMID:17498979   PMID:17531811  
PMID:18755693   PMID:18809582   PMID:19029303   PMID:19946888   PMID:20669935   PMID:20696886   PMID:21247876   PMID:21561811   PMID:21957149   PMID:22082260   PMID:22190748   PMID:22658674  
PMID:22681889   PMID:22767893   PMID:23361462   PMID:24049074   PMID:24625528   PMID:24965446   PMID:24990949   PMID:27107641   PMID:28221134   PMID:28355180   PMID:28636595  


Genomics

Comparative Map Data
Dhx9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,602,322 - 65,639,098 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1365,602,323 - 65,639,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1368,205,589 - 68,242,212 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01369,494,069 - 69,530,666 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01366,745,395 - 66,781,953 (-)NCBIRnor_WKY
Rnor_6.01370,885,503 - 70,922,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01375,851,156 - 75,887,898 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,471,256 - 68,507,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11368,485,388 - 68,522,077 (-)NCBI
Celera1365,505,727 - 65,542,475 (-)NCBICelera
Cytogenetic Map13q21NCBI
DHX9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381182,839,347 - 182,887,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1182,839,347 - 182,887,982 (+)EnsemblGRCh38hg38GRCh38
GRCh371182,808,482 - 182,857,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,075,074 - 181,123,507 (+)NCBINCBI36Build 36hg18NCBI36
Build 341179,582,076 - 179,588,539NCBI
Celera1155,919,588 - 155,968,267 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,044,114 - 154,092,793 (+)NCBIHuRef
CHM1_11184,231,696 - 184,280,375 (+)NCBICHM1_1
T2T-CHM13v2.01182,198,510 - 182,247,148 (+)NCBIT2T-CHM13v2.0
Dhx9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,331,502 - 153,363,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,331,504 - 153,363,406 (-)EnsemblGRCm39 Ensembl
GRCm381153,455,756 - 153,487,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,455,758 - 153,487,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv371155,302,888 - 155,334,790 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361155,218,031 - 155,249,826 (-)NCBIMGSCv36mm8
Celera1155,879,742 - 155,911,641 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.37NCBI
Dhx9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540621,697,813 - 21,745,011 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540621,697,813 - 21,743,551 (+)NCBIChiLan1.0ChiLan1.0
DHX9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11162,006,822 - 162,055,833 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1162,006,822 - 162,055,833 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,355,472 - 158,404,178 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DHX9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,233,763 - 16,292,576 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl716,233,814 - 16,292,618 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha715,819,539 - 15,878,326 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0715,962,809 - 16,021,792 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl715,962,805 - 16,022,144 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1715,874,239 - 15,933,191 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0715,983,090 - 16,042,030 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,112,798 - 16,171,750 (+)NCBIUU_Cfam_GSD_1.0
Dhx9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934489,049,741 - 89,088,183 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,896,359 - 6,935,623 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364816,896,487 - 6,934,938 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,141,967 - 124,185,349 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,141,929 - 124,183,838 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DHX9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12546,485,602 - 46,534,046 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2546,485,427 - 46,518,406 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605547,703,717 - 47,751,928 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481410,863,337 - 10,921,075 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462481410,863,079 - 10,923,842 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dhx9
206 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:53
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000064860
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat

Markers in Region
AA875461  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21365,602,542 - 65,602,633 (+)MAPPERmRatBN7.2
Rnor_6.01370,885,724 - 70,885,814NCBIRnor6.0
Rnor_5.01375,851,377 - 75,851,467UniSTSRnor5.0
RGSC_v3.41368,471,476 - 68,471,566UniSTSRGSC3.4
Celera1365,505,947 - 65,506,037UniSTS
RH 3.4 Map13340.3UniSTS
Cytogenetic Map13q21UniSTS
RH143807  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21365,609,221 - 65,609,374 (+)MAPPERmRatBN7.2
Rnor_6.01370,892,403 - 70,892,555NCBIRnor6.0
Rnor_5.01375,858,056 - 75,858,208UniSTSRnor5.0
RGSC_v3.41368,478,155 - 68,478,307UniSTSRGSC3.4
Celera1365,512,629 - 65,512,781UniSTS
RH 3.4 Map13340.7UniSTS
Cytogenetic Map13q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 3 5 74 35 41 11 3
Low 6 5 6 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064860   ⟹   ENSRNOP00000061368
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1365,602,323 - 65,639,069 (-)Ensembl
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116976   ⟹   ENSRNOP00000090956
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1365,602,620 - 65,639,069 (-)Ensembl
RefSeq Acc Id: NM_001107184   ⟹   NP_001100654
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,323 - 65,639,069 (-)NCBI
Rnor_6.01370,885,504 - 70,922,245 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
RGSC_v3.41368,471,256 - 68,507,999 (-)RGD
Celera1365,505,727 - 65,542,475 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249995   ⟹   XP_006250057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.01370,885,503 - 70,922,278 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249996   ⟹   XP_006250058
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.01370,885,503 - 70,922,278 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769633   ⟹   XP_008767855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,626,277 (-)NCBI
Rnor_6.01370,885,503 - 70,909,410 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001100654   ⟸   NM_001107184
- Sequence:
RefSeq Acc Id: XP_006250057   ⟸   XM_006249995
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006250058   ⟸   XM_006249996
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767855   ⟸   XM_008769633
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000061368   ⟸   ENSRNOT00000064860
RefSeq Acc Id: ENSRNOP00000090956   ⟸   ENSRNOT00000116976
Protein Domains
DRBM   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9D6-F1-model_v2 AlphaFold D4A9D6 1-1174 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698897
Promoter ID:EPDNEW_R9422
Type:initiation region
Name:Dhx9_1
Description:DExH-box helicase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01370,922,234 - 70,922,294EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308548 AgrOrtholog
BioCyc Gene G2FUF-17884 BioCyc
Ensembl Genes ENSRNOG00000002735 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000061368.1 UniProtKB/TrEMBL
  ENSRNOP00000090956 ENTREZGENE
  ENSRNOP00000090956.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064860.2 UniProtKB/TrEMBL
  ENSRNOT00000116976 ENTREZGENE
  ENSRNOT00000116976.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1080 UniProtKB/TrEMBL
  3.30.160.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD-like_N UniProtKB/TrEMBL
  DHX9_DEXHc UniProtKB/TrEMBL
  DHX9_DSRM_1 UniProtKB/TrEMBL
  DHX9_DSRM_2 UniProtKB/TrEMBL
  DNA/RNA_helicase_C UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  dsRNA-bd-like UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:304859 UniProtKB/TrEMBL
NCBI Gene 304859 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE A UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  dsrm UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Dhx9 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  DS_RBD UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  DSRM UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6ABZ7 ENTREZGENE, UniProtKB/TrEMBL
  D4A9D6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Dhx9  DExH-box helicase 9  Dhx9  DEAH-box helicase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Dhx9  DEAH-box helicase 9  Dhx9  DEAH (Asp-Glu-Ala-His) box helicase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-22 Dhx9  DEAH (Asp-Glu-Ala-His) box helicase 9  Dhx9  DEAH (Asp-Glu-Ala-His) box polypeptide 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dhx9  DEAH (Asp-Glu-Ala-His) box polypeptide 9   Dhx9_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 9 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dhx9_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED