Dhx9 (DExH-box helicase 9) - Rat Genome Database
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Gene: Dhx9 (DExH-box helicase 9) Rattus norvegicus
Analyze
Symbol: Dhx9
Name: DExH-box helicase 9
RGD ID: 1308548
Description: Predicted to have several functions, including helicase activity; nucleic acid binding activity; and ribonucleoprotein complex binding activity. Predicted to be involved in several processes, including DNA geometric change; regulation of defense response; and regulation of gene expression. Predicted to localize to several cellular components, including CRD-mediated mRNA stability complex; cytoskeleton; and nucleus. Orthologous to human DHX9 (DExH-box helicase 9); PARTICIPATES IN aldosterone signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 3H-1,2-dithiole-3-thione; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-dependent RNA helicase A; DEAH (Asp-Glu-Ala-His) box helicase 9; DEAH (Asp-Glu-Ala-His) box polypeptide 9; DEAH-box helicase 9; LOC304859
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01370,885,503 - 70,922,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01375,851,156 - 75,887,898 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,471,256 - 68,507,999 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,485,388 - 68,522,077 (-)NCBI
Celera1365,505,727 - 65,542,475 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-vinylcyclohexene dioxide  (ISO)
5-azacytidine  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bucladesine  (ISO)
cadmium dichloride  (ISO)
chloromethylisothiazolinone  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
fulvestrant  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
metformin  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
phenytoin  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
succimer  (ISO)
tert-butyl hydroperoxide  (ISO)
Testosterone propionate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alternative mRNA splicing, via spliceosome  (ISO)
biological_process  (ND)
cellular protein-containing complex assembly  (ISO)
cellular response to exogenous dsRNA  (ISO)
cellular response to heat  (ISO)
cellular response to tumor necrosis factor  (ISO)
circadian rhythm  (ISO)
CRD-mediated mRNA stabilization  (ISO)
DNA duplex unwinding  (ISO)
DNA-templated viral transcription  (ISO)
G-quadruplex DNA unwinding  (ISO)
positive regulation of cytoplasmic translation  (ISO)
positive regulation of DNA repair  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of gene silencing by miRNA  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of innate immune response  (ISO)
positive regulation of interferon-alpha production  (ISO)
positive regulation of interferon-beta production  (ISO)
positive regulation of interleukin-18 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of polysome binding  (ISO)
positive regulation of response to cytokine stimulus  (ISO)
positive regulation of RNA export from nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,ISO)
positive regulation of tumor necrosis factor production  (IEA,ISO)
positive regulation of viral transcription  (ISO)
positive regulation of viral translation  (ISO)
protein localization to cytoplasmic stress granule  (ISO)
pyroptosis  (ISO)
regulation of cytoplasmic translation  (ISO)
regulation of defense response to virus by host  (ISO)
regulation of mRNA processing  (IBA,ISO)
regulation of transcription by RNA polymerase II  (ISO)
RNA secondary structure unwinding  (ISO)
small RNA loading onto RISC  (ISO)
targeting of mRNA for destruction involved in RNA interference  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1537828   PMID:9111062   PMID:9162007   PMID:9323138   PMID:9662397   PMID:10198287   PMID:10207077   PMID:11038348   PMID:11096080   PMID:11402034   PMID:11416126   PMID:11687588  
PMID:12711669   PMID:14704337   PMID:14729462   PMID:15121898   PMID:15355351   PMID:16210410   PMID:16375861   PMID:16680162   PMID:17289661   PMID:17303075   PMID:17498979   PMID:17531811  
PMID:18755693   PMID:18809582   PMID:19029303   PMID:19946888   PMID:20669935   PMID:20696886   PMID:21247876   PMID:21561811   PMID:21957149   PMID:22082260   PMID:22190748   PMID:22658674  
PMID:22681889   PMID:22767893   PMID:23361462   PMID:24049074   PMID:24625528   PMID:24965446   PMID:24990949   PMID:27107641   PMID:28221134   PMID:28355180   PMID:28636595  


Genomics

Comparative Map Data
Dhx9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01370,885,503 - 70,922,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01375,851,156 - 75,887,898 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,471,256 - 68,507,999 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,485,388 - 68,522,077 (-)NCBI
Celera1365,505,727 - 65,542,475 (-)NCBICelera
Cytogenetic Map13q21NCBI
DHX9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1182,839,347 - 182,887,982 (+)EnsemblGRCh38hg38GRCh38
GRCh381182,839,347 - 182,887,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371182,808,482 - 182,857,117 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh371182,808,439 - 182,857,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,075,074 - 181,123,507 (+)NCBINCBI36hg18NCBI36
Build 341179,582,076 - 179,588,539NCBI
Celera1155,919,588 - 155,968,267 (+)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1154,044,114 - 154,092,793 (+)NCBIHuRef
CHM1_11184,231,696 - 184,280,375 (+)NCBICHM1_1
Dhx9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,331,502 - 153,363,464 (-)NCBIGRCm39mm39
GRCm381153,455,756 - 153,487,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,455,758 - 153,487,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv371155,302,888 - 155,334,790 (-)NCBIGRCm37mm9NCBIm37
MGSCv361155,218,031 - 155,249,826 (-)NCBImm8
Celera1155,879,742 - 155,911,641 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.37NCBI
Dhx9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540621,697,813 - 21,745,011 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540621,697,813 - 21,743,551 (+)NCBIChiLan1.0ChiLan1.0
DHX9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11162,006,822 - 162,055,833 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1162,006,822 - 162,055,833 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,355,472 - 158,404,178 (+)NCBIMhudiblu_PPA_v0panPan3
DHX9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl716,233,814 - 16,292,618 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1716,233,763 - 16,292,576 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dhx9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364816,896,487 - 6,934,938 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,093,667 - 124,185,352 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,141,929 - 124,183,838 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DHX9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12546,485,602 - 46,534,046 (-)NCBI
ChlSab1.1 Ensembl2546,485,427 - 46,518,406 (-)Ensembl
Dhx9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462481410,863,079 - 10,923,842 (-)NCBI

Position Markers
AA875461  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01370,885,724 - 70,885,814NCBIRnor6.0
Rnor_5.01375,851,377 - 75,851,467UniSTSRnor5.0
RGSC_v3.41368,471,476 - 68,471,566UniSTSRGSC3.4
Celera1365,505,947 - 65,506,037UniSTS
RH 3.4 Map13340.3UniSTS
Cytogenetic Map13q21UniSTS
RH143807  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01370,892,403 - 70,892,555NCBIRnor6.0
Rnor_5.01375,858,056 - 75,858,208UniSTSRnor5.0
RGSC_v3.41368,478,155 - 68,478,307UniSTSRGSC3.4
Celera1365,512,629 - 65,512,781UniSTS
RH 3.4 Map13340.7UniSTS
Cytogenetic Map13q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135108098996080989Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135156924896569248Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)135157782490675199Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1357903612102903612Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1362975663107975663Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136361128379034003Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)136450135182995671Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136500824591629354Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1366971778111971778Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:53
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000064860
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 3 5 74 35 41 11 3
Low 6 5 6 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064860   ⟹   ENSRNOP00000061368
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1370,885,504 - 70,922,245 (-)Ensembl
RefSeq Acc Id: NM_001107184   ⟹   NP_001100654
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,323 - 65,639,069 (-)NCBI
Rnor_6.01370,885,504 - 70,922,245 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
RGSC_v3.41368,471,256 - 68,507,999 (-)RGD
Celera1365,505,727 - 65,542,475 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249995   ⟹   XP_006250057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.01370,885,503 - 70,922,278 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249996   ⟹   XP_006250058
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,639,098 (-)NCBI
Rnor_6.01370,885,503 - 70,922,278 (-)NCBI
Rnor_5.01375,851,156 - 75,887,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769633   ⟹   XP_008767855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,602,322 - 65,626,277 (-)NCBI
Rnor_6.01370,885,503 - 70,909,410 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100654 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250057 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250058 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767855 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM09547 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100654   ⟸   NM_001107184
- UniProtKB: D4A9D6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250057   ⟸   XM_006249995
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006250058   ⟸   XM_006249996
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767855   ⟸   XM_008769633
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000061368   ⟸   ENSRNOT00000064860
Protein Domains
DRBM   Helicase ATP-binding   Helicase C-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698897
Promoter ID:EPDNEW_R9422
Type:initiation region
Name:Dhx9_1
Description:DExH-box helicase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01370,922,234 - 70,922,294EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 68481041 68481042 G C snv SS/JrHsdMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308548 AgrOrtholog
Ensembl Genes ENSRNOG00000002735 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000061368 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064860 ENTREZGENE, UniProtKB/TrEMBL
InterPro DEAD-like_N UniProtKB/TrEMBL
  DNA/RNA_helicase_C UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  dsRNA-bd-like UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:304859 UniProtKB/TrEMBL
NCBI Gene 304859 ENTREZGENE
Pfam DEAD UniProtKB/TrEMBL
  dsrm UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Dhx9 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  DS_RBD UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  DSRM UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt D4A9D6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Dhx9  DExH-box helicase 9  Dhx9  DEAH-box helicase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Dhx9  DEAH-box helicase 9  Dhx9  DEAH (Asp-Glu-Ala-His) box helicase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-22 Dhx9  DEAH (Asp-Glu-Ala-His) box helicase 9  Dhx9  DEAH (Asp-Glu-Ala-His) box polypeptide 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dhx9  DEAH (Asp-Glu-Ala-His) box polypeptide 9   Dhx9_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 9 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dhx9_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED