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Gene: Tnnt2 (troponin T2, cardiac type) Rattus norvegicus
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Symbol: Tnnt2
Name: troponin T2, cardiac type
Description: Exhibits protein binding activity, bridging and troponin I binding activity. Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in actin crosslink formation; cardiac muscle contraction; and regulation of muscle filament sliding speed. Localizes to the troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (E)-thiamethoxam; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cardiac muscle troponin T; cardiac troponin T2; cTnT; Ctt; CTTG; RATCTTG; Tnnt3; tnTc; Troponin T cardiac; troponin T type 2 (cardiac); Troponin T, cardiac; troponin T, cardiac muscle; troponin T2; troponin T2 cardiac; troponin T2, cardiac
Orthologs:
Homo sapiens (human) : TNNT2 (troponin T2, cardiac type)  HGNC  Alliance
Mus musculus (house mouse) : Tnnt2 (troponin T2, cardiac)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnnt2 (troponin T2, cardiac type)
Pan paniscus (bonobo/pygmy chimpanzee) : TNNT2 (troponin T2, cardiac type)
Canis lupus familiaris (dog) : TNNT2 (troponin T2, cardiac type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnnt2 (troponin T2, cardiac type)
Sus scrofa (pig) : TNNT2 (troponin T2, cardiac type)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01352,662,974 - 52,680,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,662,996 - 52,680,990 (+)Ensembl
Rnor_5.01357,711,369 - 57,729,182 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,872,972 - 48,885,815 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11348,887,014 - 48,899,858 (+)NCBI
Celera1347,589,409 - 47,602,135 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tnnt2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3882
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.