Aldh9a1 (aldehyde dehydrogenase 9 family, member A1) - Rat Genome Database

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Gene: Aldh9a1 (aldehyde dehydrogenase 9 family, member A1) Rattus norvegicus
Analyze
Symbol: Aldh9a1
Name: aldehyde dehydrogenase 9 family, member A1
RGD ID: 68409
Description: Enables several functions, including NAD binding activity; identical protein binding activity; and oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Involved in kidney development and liver development. Located in cytoplasm. Orthologous to human ALDH9A1 (aldehyde dehydrogenase 9 family member A1); PARTICIPATES IN carnitine biosynthetic pathway; arginine and proline metabolic pathway; ascorbate and aldarate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 4-trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase-like; aldehyde dehydrogenase 9A1; aldehyde dehydrogenase family 9 member A1; aldehyde dehydrogenase family 9, subfamily A1; formaldehyde dehydrogenase; gamma-aminobutyraldehyde dehydrogenase; gamma-trimethylaminobutyraldehyde dehydrogenase; LOC100910278; Tmaba-dh; TMABADH
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21379,505,738 - 79,522,539 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,505,695 - 79,540,568 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,135,618 - 82,152,413 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,442,832 - 83,459,515 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,680,560 - 80,697,225 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,580,828 - 85,597,497 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,580,828 - 85,597,493 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,223,961 - 90,240,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,017,312 - 83,034,047 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,031,512 - 83,047,451 (+)NCBI
Celera1379,210,686 - 79,227,775 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetaldehyde  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arecoline  (ISO)
arsenite(3-)  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
cannabidiol  (ISO)
chlorpyrifos  (EXP)
choline  (EXP,ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
clotrimazole  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP,ISO)
doxorubicin  (ISO)
fenpyroximate  (ISO)
flutamide  (EXP)
folic acid  (EXP,ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (EXP)
hydralazine  (ISO)
imidacloprid  (EXP)
indometacin  (EXP)
inulin  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
L-methionine  (EXP,ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methoxyacetic acid  (EXP)
methylmercury chloride  (EXP)
microcystin-LR  (EXP)
Monobutylphthalate  (EXP)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorododecanoic acid  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
quercetin  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tetrachloromethane  (EXP)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Aldehyde dehydrogenase (EC 1.2.1.3): comparison of subcellular localization of the third isozyme that dehydrogenates gamma-aminobutyraldehyde in rat, guinea pig and human liver. Ambroziak W, etal., Comp Biochem Physiol B. 1991;100(2):321-7. doi: 10.1016/0305-0491(91)90382-n.
2. Ontogeny of Na(+)/L-carnitine transporter and of gamma-trimethylaminobutyraldehyde dehydrogenase and gamma-butyrobetaine hydroxylase genes expression in rat kidney. Garcia-Delgado M, etal., Mech Ageing Dev. 2009 Apr;130(4):227-33. Epub 2008 Dec 27.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. Aldehyde dehydrogenase from rat intestinal mucosa: purification and characterization of an isozyme with high affinity for gamma-aminobutyraldehyde. Testore G, etal., Int J Biochem Cell Biol. 1999 Jul;31(7):777-86.
16. Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis. Vaz FM, etal., J Biol Chem 2000 Mar 10;275(10):7390-4.
Additional References at PubMed
PMID:2925663   PMID:8645224   PMID:15489334   PMID:18614015   PMID:19056867   PMID:23376485   PMID:23533145   PMID:26010099   PMID:26316108   PMID:30914451  


Genomics

Comparative Map Data
Aldh9a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21379,505,738 - 79,522,539 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,505,695 - 79,540,568 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,135,618 - 82,152,413 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,442,832 - 83,459,515 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,680,560 - 80,697,225 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,580,828 - 85,597,497 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,580,828 - 85,597,493 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,223,961 - 90,240,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,017,312 - 83,034,047 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,031,512 - 83,047,451 (+)NCBI
Celera1379,210,686 - 79,227,775 (+)NCBICelera
Cytogenetic Map13q24NCBI
ALDH9A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,662,216 - 165,698,562 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,662,216 - 165,698,562 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,631,453 - 165,667,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,898,073 - 163,934,524 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,363,110 - 162,399,758NCBI
Celera1138,736,605 - 138,773,321 (-)NCBICelera
Cytogenetic Map1q24.1NCBI
HuRef1136,878,922 - 136,915,629 (-)NCBIHuRef
CHM1_11167,054,030 - 167,090,476 (-)NCBICHM1_1
T2T-CHM13v2.01165,008,653 - 165,044,991 (-)NCBIT2T-CHM13v2.0
Aldh9a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,177,560 - 167,196,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,177,560 - 167,196,101 (+)EnsemblGRCm39 Ensembl
GRCm381167,349,963 - 167,368,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,349,991 - 167,368,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,280,122 - 169,298,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,186,888 - 169,204,961 (+)NCBIMGSCv36mm8
Celera1169,767,504 - 169,786,077 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.74NCBI
Aldh9a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546210,998,147 - 11,017,360 (+)NCBIChiLan1.0ChiLan1.0
ALDH9A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1183,735,548 - 83,772,060 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01141,094,261 - 141,130,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,883,828 - 144,919,718 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,883,839 - 144,919,670 (-)Ensemblpanpan1.1panPan2
ALDH9A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,644,464 - 17,664,462 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,644,459 - 17,663,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,701,135 - 17,721,198 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,699,030 - 17,719,264 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13817,698,130 - 17,718,197 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,049,253 - 18,069,354 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,343,405 - 18,363,616 (+)NCBIUU_Cfam_GSD_1.0
Aldh9a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,783,295 - 101,803,263 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648119,630,045 - 19,650,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH9A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1485,029,914 - 85,057,650 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,685,909 - 92,713,569 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH9A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,184,220 - 63,223,865 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605564,944,943 - 64,983,521 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh9a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248263,994,183 - 4,026,696 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248263,994,188 - 4,026,437 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aldh9a1
123 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:617
Count of miRNA genes:278
Interacting mature miRNAs:337
Transcripts:ENSRNOT00000005611
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)137402391880753406Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat

Markers in Region
RH140157  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01390,239,895 - 90,240,076NCBIRnor5.0
Rnor_5.01390,144,166 - 90,144,347NCBIRnor5.0
Rnor_5.01467,745,544 - 67,745,725NCBIRnor5.0
RGSC_v3.41468,349,092 - 68,349,272UniSTSRGSC3.4
RGSC_v3.41383,033,757 - 83,033,937UniSTSRGSC3.4
Celera1462,422,419 - 62,422,599UniSTS
Celera1379,227,485 - 79,227,665UniSTS
RH 3.4 Map13523.5UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000005611   ⟹   ENSRNOP00000005611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,505,725 - 79,522,539 (+)Ensembl
Rnor_6.0 Ensembl1385,580,828 - 85,597,493 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095838   ⟹   ENSRNOP00000096230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,505,784 - 79,540,568 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105128   ⟹   ENSRNOP00000097830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,505,695 - 79,521,753 (+)Ensembl
RefSeq Acc Id: NM_022273   ⟹   NP_071609
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21379,505,738 - 79,522,539 (+)NCBI
Rnor_6.01385,580,828 - 85,597,497 (+)NCBI
Rnor_5.01390,223,961 - 90,240,186 (+)NCBI
RGSC_v3.41383,017,312 - 83,034,047 (+)RGD
Celera1379,210,686 - 79,227,775 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_071609 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF43598 (Get FASTA)   NCBI Sequence Viewer  
  AAH74019 (Get FASTA)   NCBI Sequence Viewer  
  EDM09283 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005611
  ENSRNOP00000005611.6
  ENSRNOP00000096230.1
  ENSRNOP00000097830.1
GenBank Protein Q9JLJ3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071609   ⟸   NM_022273
- UniProtKB: Q6GMM4 (UniProtKB/Swiss-Prot),   Q9JLJ3 (UniProtKB/Swiss-Prot),   A0A8I6AQJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005611   ⟸   ENSRNOT00000005611
RefSeq Acc Id: ENSRNOP00000097830   ⟸   ENSRNOT00000105128
RefSeq Acc Id: ENSRNOP00000096230   ⟸   ENSRNOT00000095838
Protein Domains
Aldehyde dehydrogenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JLJ3-F1-model_v2 AlphaFold Q9JLJ3 1-494 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698973
Promoter ID:EPDNEW_R9498
Type:initiation region
Name:Aldh9a1_1
Description:aldehyde dehydrogenase 9 family, member A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01385,580,819 - 85,580,879EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68409 AgrOrtholog
BioCyc Gene G2FUF-17522 BioCyc
BioCyc Pathway PWY-6100 [L-carnitine biosynthesis] BioCyc
BioCyc Pathway Image PWY-6100 BioCyc
Ensembl Genes ENSRNOG00000004027 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005611 ENTREZGENE
  ENSRNOT00000005611.6 UniProtKB/TrEMBL
  ENSRNOT00000095838.1 UniProtKB/TrEMBL
  ENSRNOT00000105128.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104823 IMAGE-MGC_LOAD
InterPro Ald_DH/histidinol_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64040 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91695 IMAGE-MGC_LOAD
NCBI Gene 64040 ENTREZGENE
PANTHER 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aldh9a1 PhenoGen
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004027 RatGTEx
Superfamily-SCOP SSF53720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228379
UniProt A0A0G2JSI1_RAT UniProtKB/TrEMBL
  A0A8I6AQJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASL3_RAT UniProtKB/TrEMBL
  A6IDL4_RAT UniProtKB/TrEMBL
  AL9A1_RAT UniProtKB/Swiss-Prot
  Q6GMM4 ENTREZGENE
  Q9JLJ3 ENTREZGENE
UniProt Secondary Q6GMM4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Aldh9a1  aldehyde dehydrogenase 9 family, member A1  LOC100910278  4-trimethylaminobutyraldehyde dehydrogenase-like  Data merged from RGD:6499178 737654 PROVISIONAL
2012-07-05 LOC100910278  4-trimethylaminobutyraldehyde dehydrogenase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-18 Aldh9a1  aldehyde dehydrogenase 9 family, member A1  Aldh9a1  aldehyde dehydrogenase family 9, subfamily A1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Aldh9a1  aldehyde dehydrogenase family 9, subfamily A1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference