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Gene: Fh (fumarate hydratase) Rattus norvegicus
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Symbol: Fh
Name: fumarate hydratase
Description: Exhibits fumarate hydratase activity. Involved in fumarate metabolic process; malate metabolic process; and tricarboxylic acid cycle. Localizes to the mitochondrion. Orthologous to human FH (fumarate hydratase); PARTICIPATES IN citric acid cycle pathway; altered citric acid cycle pathway; fumaric aciduria pathway; INTERACTS WITH (+)-schisandrin B; (R)-adrenaline; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fh1; fumarase; fumarate hydratase 1; fumarate hydratase, mitochondrial; MGC105468
Orthologs:
Homo sapiens (human) : FH (fumarate hydratase)  HGNC  Alliance
Mus musculus (house mouse) : Fh1 (fumarate hydratase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fh (fumarate hydratase)
Pan paniscus (bonobo/pygmy chimpanzee) : FH (fumarate hydratase)
Canis lupus familiaris (dog) : FH (fumarate hydratase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fh (fumarate hydratase)
Sus scrofa (pig) : FH (fumarate hydratase)
more info ...
Allele / Splice: Fhem1  
Genetic Models: SD-Fhem1+/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01393,651,486 - 93,677,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01398,116,496 - 98,142,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41391,329,837 - 91,355,722 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11391,518,725 - 91,544,617 (-)NCBI
Celera1387,123,119 - 87,148,786 (-)NCBICelera
Cytogenetic Map13q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2614
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.