Gene: Rgs4 (regulator of G-protein signaling 4) Rattus norvegicus
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Symbol: Rgs4
Name: regulator of G-protein signaling 4
Description: Exhibits G-protein alpha-subunit binding activity and GTPase activator activity; involved in several processes, including animal organ development, regulation of ion transport, and regulation of signal transduction; localizes to several cellular components, including the cytosol, nucleus, and plasma membrane; used to study epilepsy; biomarker of bladder disease, hypertension, lesion of sciatic nerve, opioid abuse, and status epilepticus; orthologous to human RGS4 (regulator of G protein signaling 4); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; INTERACTS WITH (RS)-amphetamine; (S)-amphetamine; 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: RGP4
Orthologs:
Homo sapiens (human) : RGS4 (regulator of G protein signaling 4)  HGNC  Alliance
Mus musculus (house mouse) : Rgs4 (regulator of G-protein signaling 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs4 (regulator of G protein signaling 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS4 (regulator of G protein signaling 4)
Canis lupus familiaris (dog) : RGS4 (regulator of G protein signaling 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs4 (regulator of G protein signaling 4)
Sus scrofa (pig) : RGS4 (regulator of G protein signaling 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01388,054,817 - 88,061,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01392,682,956 - 92,689,247 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,533,882 - 85,540,173 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11385,548,069 - 85,554,361 (-)NCBI
Celera1381,602,391 - 81,608,682 (-)NCBICelera
Cytogenetic Map13q24NCBI
RH 3.4 Map13510.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Rgs4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3567
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.