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Gene: Rgs4 (regulator of G-protein signaling 4) Mus musculus
Symbol: Rgs4
Name: regulator of G-protein signaling 4
Description: Predicted to have G-protein alpha-subunit binding activity and GTPase activator activity. Predicted to be involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; regulation of ion transport; and regulation of signal transduction. Predicted to localize to several cellular components, including cytosol; nucleus; and plasma membrane. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Orthologous to human RGS4 (regulator of G protein signaling 4); PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; dopamine signaling pathway via D2 family of receptors; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA004315; AA597169; ESTM48; ESTM50
Homo sapiens (human) : RGS4 (regulator of G protein signaling 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rgs4 (regulator of G-protein signaling 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs4 (regulator of G protein signaling 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS4 (regulator of G protein signaling 4)
Canis lupus familiaris (dog) : RGS4 (regulator of G protein signaling 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs4 (regulator of G protein signaling 4)
Sus scrofa (pig) : RGS4 (regulator of G protein signaling 4)
Chlorocebus sabaeus (African green monkey) : RGS4 (regulator of G protein signaling 4)
Heterocephalus glaber (naked mole-rat) : Rgs4 (regulator of G protein signaling 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1169,741,477 - 169,747,642 (-)EnsemblGRCm38mm10GRCm38
GRCm381169,741,477 - 169,747,642 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371171,671,608 - 171,677,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,578,350 - 171,584,295 (-)NCBImm8
Celera1172,167,498 - 172,173,650 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map176.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rgs4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70083
Created: 2002-01-22
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.