Rgs4 (regulator of G protein signaling 4) - Rat Genome Database

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Gene: Rgs4 (regulator of G protein signaling 4) Chinchilla lanigera
Analyze
Symbol: Rgs4
Name: regulator of G protein signaling 4
RGD ID: 8826588
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); protein kinase binding (ortholog); INVOLVED IN dorsal root ganglion development (ortholog); negative regulation of cell growth involved in cardiac muscle cell development (ortholog); negative regulation of dopamine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH bladder disease (ortholog); Drug-Induced Dyskinesia (ortholog); endometriosis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,338,960 - 13,347,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,340,812 - 13,347,598 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Rgs4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,338,960 - 13,347,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,340,812 - 13,347,598 (-)NCBIChiLan1.0ChiLan1.0
RGS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381163,068,871 - 163,076,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1163,068,775 - 163,076,802 (+)EnsemblGRCh38hg38GRCh38
GRCh371163,038,661 - 163,046,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,305,285 - 161,313,216 (+)NCBINCBI36Build 36hg18NCBI36
Build 341159,770,808 - 159,778,036NCBI
Celera1136,142,715 - 136,150,908 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1134,283,724 - 134,291,924 (+)NCBIHuRef
CHM1_11164,461,279 - 164,469,481 (+)NCBICHM1_1
T2T-CHM13v2.01162,413,422 - 162,421,357 (+)NCBIT2T-CHM13v2.0
Rgs4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,569,046 - 169,575,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,569,046 - 169,575,211 (-)EnsemblGRCm39 Ensembl
GRCm381169,741,477 - 169,747,642 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,741,477 - 169,747,642 (-)EnsemblGRCm38mm10GRCm38
MGSCv371171,671,608 - 171,677,773 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361171,578,350 - 171,584,295 (-)NCBIMGSCv36mm8
Celera1172,167,498 - 172,173,650 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map176.84NCBI
Rgs4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81384,469,593 - 84,475,884 (-)NCBIGRCr8
mRatBN7.21381,936,775 - 81,943,103 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1381,936,775 - 81,943,068 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1384,564,610 - 84,570,879 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01385,857,386 - 85,863,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01383,089,853 - 83,096,122 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01388,054,817 - 88,061,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1388,054,817 - 88,061,108 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01392,682,956 - 92,689,247 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,533,882 - 85,540,173 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11385,548,069 - 85,554,361 (-)NCBI
Celera1381,602,391 - 81,608,682 (-)NCBICelera
RH 3.4 Map13510.9RGD
Cytogenetic Map13q24NCBI
RGS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2186,701,675 - 86,709,417 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1186,370,272 - 86,378,015 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01138,488,317 - 138,496,497 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11142,284,040 - 142,292,225 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1142,284,040 - 142,292,225 (+)Ensemblpanpan1.1panPan2
RGS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13819,771,454 - 19,778,917 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3819,771,441 - 19,779,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3819,826,659 - 19,834,129 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03819,854,868 - 19,862,329 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3819,824,617 - 19,862,433 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13819,830,174 - 19,837,642 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03820,181,940 - 20,189,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03820,473,021 - 20,480,491 (-)NCBIUU_Cfam_GSD_1.0
Rgs4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344103,671,010 - 103,678,611 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937238102,061 - 109,474 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004937238101,948 - 109,513 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl487,383,345 - 87,390,893 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1487,383,336 - 87,390,478 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2495,096,206 - 95,103,332 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12565,729,344 - 65,735,278 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2565,726,394 - 65,735,381 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605567,526,009 - 67,532,206 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248261,569,854 - 1,579,627 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248261,570,143 - 1,577,300 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000013267   ⟹   ENSCLAP00000013116
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546213,338,960 - 13,347,610 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000013268   ⟹   ENSCLAP00000013117
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546213,342,971 - 13,347,598 (-)Ensembl
RefSeq Acc Id: XM_005398260   ⟹   XP_005398317
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546213,340,812 - 13,347,598 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005398261   ⟹   XP_005398318
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546213,342,971 - 13,347,598 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398317 (Get FASTA)   NCBI Sequence Viewer  
  XP_005398318 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013116
  ENSCLAP00000013116.1
  ENSCLAP00000013117
  ENSCLAP00000013117.1
RefSeq Acc Id: XP_005398317   ⟸   XM_005398260
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VBH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398318   ⟸   XM_005398261
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YP72 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000013117   ⟸   ENSCLAT00000013268
Ensembl Acc Id: ENSCLAP00000013116   ⟸   ENSCLAT00000013267
Protein Domains
RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009055 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013267 ENTREZGENE
  ENSCLAT00000013267.1 UniProtKB/TrEMBL
  ENSCLAT00000013268 ENTREZGENE
  ENSCLAT00000013268.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS_RGS4 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
NCBI Gene Rgs4 ENTREZGENE
PANTHER PTHR10845:SF184 UniProtKB/TrEMBL
  REGULATOR OF G PROTEIN SIGNALING UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A8C2VBH3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YP72 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-29 Rgs4  regulator of G protein signaling 4    regulator of G-protein signaling 4  Symbol and/or name change 5135510 APPROVED