RGS4 (regulator of G protein signaling 4) - Rat Genome Database
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Gene: RGS4 (regulator of G protein signaling 4) Pan paniscus
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Symbol: RGS4
Name: regulator of G protein signaling 4
RGD ID: 11899310
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); INVOLVED IN brain development (ortholog); dorsal root ganglion development (ortholog); negative regulation of cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; calcium signaling pathway via the calcium-sensing receptor; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH bladder disease (ortholog); Drug-Induced Dyskinesia (ortholog); endometriosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: regulator of G-protein signaling 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11142,284,040 - 142,292,225 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1142,284,040 - 142,292,225 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01138,488,317 - 138,496,497 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
RGS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11142,284,040 - 142,292,225 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1142,284,040 - 142,292,225 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01138,488,317 - 138,496,497 (+)NCBIMhudiblu_PPA_v0panPan3
RGS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1163,068,775 - 163,076,802 (+)EnsemblGRCh38hg38GRCh38
GRCh381163,068,871 - 163,076,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371163,038,396 - 163,046,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,305,285 - 161,313,216 (+)NCBINCBI36hg18NCBI36
Build 341159,770,808 - 159,778,036NCBI
Celera1136,142,715 - 136,150,908 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1134,283,724 - 134,291,924 (+)NCBIHuRef
CHM1_11164,461,279 - 164,469,481 (+)NCBICHM1_1
Rgs4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,569,046 - 169,575,211 (-)NCBIGRCm39mm39
GRCm381169,741,477 - 169,747,642 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,741,477 - 169,747,642 (-)EnsemblGRCm38mm10GRCm38
MGSCv371171,671,608 - 171,677,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,578,350 - 171,584,295 (-)NCBImm8
Celera1172,167,498 - 172,173,650 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map176.84NCBI
Rgs4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01388,054,817 - 88,061,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1388,054,817 - 88,061,108 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01392,682,956 - 92,689,247 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,533,882 - 85,540,173 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11385,548,069 - 85,554,361 (-)NCBI
Celera1381,602,391 - 81,608,682 (-)NCBICelera
Cytogenetic Map13q24NCBI
RH 3.4 Map13510.9RGD
Rgs4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,338,960 - 13,347,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,340,812 - 13,347,598 (-)NCBIChiLan1.0ChiLan1.0
RGS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3819,771,441 - 19,779,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13819,771,454 - 19,778,917 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rgs4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004937238101,948 - 109,513 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl487,381,386 - 87,390,467 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1487,383,336 - 87,390,478 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2495,096,206 - 95,103,332 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12565,729,344 - 65,735,278 (-)NCBI
ChlSab1.1 Ensembl2565,726,394 - 65,735,381 (-)Ensembl
Rgs4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248261,570,143 - 1,577,300 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003824574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000041382   ⟹   ENSPPAP00000018648
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1142,284,040 - 142,292,225 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041396   ⟹   ENSPPAP00000018662
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1142,284,920 - 142,289,996 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041400   ⟹   ENSPPAP00000018664
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1142,284,920 - 142,289,827 (+)Ensembl
RefSeq Acc Id: XM_003824574   ⟹   XP_003824622
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11142,284,040 - 142,292,225 (+)NCBI
Mhudiblu_PPA_v01138,488,317 - 138,496,497 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003824622 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003824622   ⟸   XM_003824574
- Sequence:
RefSeq Acc Id: ENSPPAP00000018648   ⟸   ENSPPAT00000041382
RefSeq Acc Id: ENSPPAP00000018662   ⟸   ENSPPAT00000041396
RefSeq Acc Id: ENSPPAP00000018664   ⟸   ENSPPAT00000041400
Protein Domains
RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032457 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000018648 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000018662 UniProtKB/TrEMBL
  ENSPPAP00000018664 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041382 UniProtKB/TrEMBL
  ENSPPAT00000041396 UniProtKB/TrEMBL
  ENSPPAT00000041400 UniProtKB/TrEMBL
Gene3D-CATH 1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS4 UniProtKB/TrEMBL
  RGS_RGS4 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
KEGG Report pps:100988394 UniProtKB/TrEMBL
NCBI Gene RGS4 ENTREZGENE
PANTHER PTHR10845:SF184 UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A2R9AMT0_PANPA UniProtKB/TrEMBL
  A0A2R9ANC1_PANPA UniProtKB/TrEMBL
  A0A2R9AUR5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-07 RGS4  regulator of G protein signaling 4    regulator of G-protein signaling 4  Symbol and/or name change 5135510 APPROVED