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Gene: Gnao1 (G protein subunit alpha o1) Rattus norvegicus
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Symbol: Gnao1
Name: G protein subunit alpha o1
Description: Exhibits several functions, including G protein-coupled receptor binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including aging; nervous system development; and response to morphine. Localizes to several cellular components, including the myelin sheath; neuron projection; and protein-containing complex. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 17. Orthologous to human GNAO1 (G protein subunit alpha o1); PARTICIPATES IN G protein mediated signaling pathway; dopamine signaling pathway via D2 family of receptors; endothelin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Gnao; GTP-binding protein; GTP-binding protein alpha o; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; guanine nucleotide binding protein, alpha O; guanine nucleotide binding protein, alpha O polypeptide 1; guanine nucleotide-binding protein G(o) subunit alpha; RATBPGTPC
Orthologs:
Homo sapiens (human) : GNAO1 (G protein subunit alpha o1)  HGNC  Alliance
Mus musculus (house mouse) : Gnao1 (guanine nucleotide binding protein, alpha O)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnao1 (G protein subunit alpha o1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAO1 (G protein subunit alpha o1)
Canis lupus familiaris (dog) : GNAO1 (G protein subunit alpha o1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnao1 (G protein subunit alpha o1)
Sus scrofa (pig) : GNAO1 (G protein subunit alpha o1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01911,513,201 - 11,669,578 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01911,487,578 - 11,643,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41911,472,083 - 11,623,600 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11911,476,908 - 11,628,426 (-)NCBI
Celera1910,919,521 - 11,074,052 (-)NCBICelera
Cytogenetic Map19p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gnao1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628732
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.