Oprm1 (opioid receptor, mu 1) - Rat Genome Database
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Gene: Oprm1 (opioid receptor, mu 1) Rattus norvegicus
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Symbol: Oprm1
Name: opioid receptor, mu 1
RGD ID: 3234
Description: Exhibits several functions, including G-protein beta-subunit binding activity; filamin binding activity; and morphine receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of signal transduction; and response to alkaloid. Localizes to several cellular components, including focal adhesion; integral component of synaptic membrane; and perikaryon. Colocalizes with sarcolemma. Biomarker of brain ischemia and human immunodeficiency virus infectious disease. Orthologous to human OPRM1 (opioid receptor mu 1); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (3,4-dihydroxyphenyl)acetic acid; (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: M-OR-1; MOR-1; MORA; mu opioid receptor; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; mu-type opioid receptor; MUOR1; opioid receptor B; Oprm; Oprrm1
Orthologs:
Homo sapiens (human) : OPRM1 (opioid receptor mu 1)  HGNC  Alliance
Mus musculus (house mouse) : Oprm1 (opioid receptor, mu 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprm1 (opioid receptor mu 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRM1 (opioid receptor mu 1)
Canis lupus familiaris (dog) : OPRM1 (opioid receptor mu 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprm1 (opioid receptor mu 1)
Sus scrofa (pig) : OPRM1 (opioid receptor mu 1)
Chlorocebus sabaeus (African green monkey) : OPRM1 (opioid receptor mu 1)
Heterocephalus glaber (naked mole-rat) : Oprm1 (opioid receptor mu 1)
more info ...
Allele / Splice: Oprm1_v3   Oprm1_v1   Oprm1_v2   Oprm1_v4  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0143,454,803 - 43,704,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,454,803 - 43,704,948 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0144,804,181 - 45,034,145 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4137,535,416 - 37,779,392 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1137,538,384 - 37,591,800 (+)NCBI
Celera138,804,246 - 39,057,359 (+)NCBICelera
Cytogenetic Map1q11NCBI
RH 3.4 Map1468.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin  (EXP,ISO)
(R)-noradrenaline  (EXP)
(R,R)-tramadol  (EXP)
(S)-amphetamine  (EXP)
(S)-nicotine  (ISO)
1,1,1-trichloroethane  (ISO)
1,2-dichloroethane  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3',5'-cyclic AMP  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
7-Benzylidenenaltrexone  (ISO)
acetylmethadol  (EXP)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
alcohol  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (EXP)
alvimopan  (ISO)
ammonium chloride  (EXP)
benzamide  (ISO)
benzo[a]pyrene  (ISO)
beta-Funaltrexamine  (EXP,ISO)
bisphenol A  (EXP)
buprenorphine  (EXP,ISO)
butan-1-ol  (EXP)
butorphanol  (EXP,ISO)
cadmium atom  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP)
capsaicin  (ISO)
carbon nanotube  (ISO)
carfentanil  (ISO)
carrageenan  (ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
cocaine  (EXP,ISO)
codeine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
dextromethorphan  (EXP)
dextropropoxyphene  (EXP)
dextrorphan  (EXP)
diisopropyl fluorophosphate  (ISO)
DPDPE  (EXP)
dynorphin A  (EXP,ISO)
Endomorphin-1  (ISO)
Endomorphin-2  (ISO)
ethanol  (ISO)
fentanyl  (ISO)
fluoxetine  (EXP,ISO)
furan  (EXP)
gamma-aminobutyric acid  (ISO)
genistein  (ISO)
GTP  (EXP)
guanosine 5'-[gamma-thio]triphosphate  (ISO)
haloperidol  (ISO)
homovanillic acid  (EXP)
hydrocodone  (EXP)
Levallorphan  (EXP)
Levorphanol  (EXP)
lithium chloride  (EXP)
magnesium atom  (EXP)
manganese atom  (EXP)
manganese(0)  (EXP)
mercury atom  (EXP)
mercury(0)  (EXP)
methadone  (EXP)
methamphetamine  (EXP,ISO)
methotrexate  (ISO)
methylnaltrexone  (ISO)
Mitragynine  (ISO)
morphine  (EXP,ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-ethyl-N-nitrosourea  (EXP)
Nalmefene  (ISO)
naloxone  (EXP,ISO)
naltrexone  (EXP,ISO)
nicotine  (ISO)
Nonylphenol  (EXP)
oxycodone  (EXP)
Oxymorphone  (EXP,ISO)
paraquat  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidic acid  (EXP)
picrotoxin  (EXP)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
serotonin  (EXP)
sodium arsenite  (ISO)
sulfasalazine  (ISO)
tapentadol  (EXP,ISO)
thioglycolic acid  (EXP)
tramadol  (EXP)
trichostatin A  (ISO)
U69593  (EXP)
valproic acid  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute inflammatory response to antigenic stimulus  (IEP)
adenylate cyclase-activating dopamine receptor signaling pathway  (ISO)
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway  (IDA)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (IDA,ISO)
adenylate cyclase-inhibiting opioid receptor signaling pathway  (IDA)
behavioral response to ethanol  (ISO)
calcium ion transmembrane transport  (IEA)
cellular response to morphine  (IEA)
eating behavior  (IMP)
estrous cycle  (IEP)
excitatory postsynaptic potential  (IDA)
G protein-coupled receptor signaling pathway  (IDA)
immune response  (TAS)
locomotory behavior  (ISO)
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IDA)
negative regulation of cAMP-mediated signaling  (ISO,ISS)
negative regulation of cytosolic calcium ion concentration  (ISO,ISS)
negative regulation of nitric oxide biosynthetic process  (ISO,ISS)
negative regulation of Wnt protein secretion  (ISO,ISS)
neuropeptide signaling pathway  (IBA,IEA)
opioid receptor signaling pathway  (IBA,IDA,IEA)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IDA)
positive regulation of appetite  (IMP)
positive regulation of cAMP-mediated signaling  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of neurogenesis  (ISO,ISS)
positive regulation of nitric oxide biosynthetic process  (ISO)
regulation of cellular response to stress  (ISO)
regulation of NMDA receptor activity  (IMP)
regulation of sensory perception of pain  (IDA,IMP)
response to cocaine  (IEP)
response to ethanol  (IDA)
response to food  (IEP)
response to growth factor  (IEP)
response to lipopolysaccharide  (IEP)
response to morphine  (IEP)
response to radiation  (IEP)
sensory perception of pain  (IBA,ISO,ISS)
wound healing  (IEP)

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacokinetics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
heroin pharmacokinetics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
interleukin-4 signaling pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
methadone pharmacokinetics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References

References - curated
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Additional References at PubMed
PMID:7532594   PMID:7733926   PMID:8189219   PMID:8240812   PMID:8393525   PMID:8738226   PMID:9037090   PMID:9689128   PMID:9915326   PMID:10835636   PMID:11304756   PMID:11994125  
PMID:12000113   PMID:12574430   PMID:12732339   PMID:12855366   PMID:12867258   PMID:12899684   PMID:12906839   PMID:14532289   PMID:14689476   PMID:14960335   PMID:15101090   PMID:15236578  
PMID:15306235   PMID:15308614   PMID:15322094   PMID:15327807   PMID:15467355   PMID:15659552   PMID:15857395   PMID:15950784   PMID:15967419   PMID:16139823   PMID:16140499   PMID:16159882  
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PMID:29589831   PMID:31030416   PMID:31310777  


Genomics

Comparative Map Data
Oprm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0143,454,803 - 43,704,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,454,803 - 43,704,948 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0144,804,181 - 45,034,145 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4137,535,416 - 37,779,392 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1137,538,384 - 37,591,800 (+)NCBI
Celera138,804,246 - 39,057,359 (+)NCBICelera
Cytogenetic Map1q11NCBI
RH 3.4 Map1468.6RGD
OPRM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6154,010,496 - 154,246,867 (+)EnsemblGRCh38hg38GRCh38
GRCh386154,010,496 - 154,246,867 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376154,331,631 - 154,568,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366154,402,136 - 154,609,693 (+)NCBINCBI36hg18NCBI36
Build 346154,452,556 - 154,660,114NCBI
Celera6155,066,098 - 155,302,376 (+)NCBI
Cytogenetic Map6q25.2NCBI
HuRef6151,895,214 - 152,131,143 (+)NCBIHuRef
CHM1_16154,595,701 - 154,831,638 (+)NCBICHM1_1
Oprm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39106,708,593 - 6,988,209 (+)NCBI
GRCm38106,758,593 - 7,038,209 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl106,758,506 - 7,038,198 (+)EnsemblGRCm38mm10GRCm38
MGSCv37103,308,332 - 3,557,940 (-)NCBIGRCm37mm9NCBIm37
MGSCv36103,309,340 - 3,557,732 (-)NCBImm8
Celera106,736,075 - 7,000,690 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map101.85NCBI
Oprm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554397,757,569 - 7,923,817 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554397,870,563 - 7,923,817 (-)NCBIChiLan1.0ChiLan1.0
OPRM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16156,517,666 - 156,627,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6156,517,661 - 157,088,251 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06151,827,323 - 151,937,658 (+)NCBIMhudiblu_PPA_v0panPan3
OPRM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl143,972,219 - 44,141,238 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1143,972,915 - 44,037,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Oprm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364896,506,207 - 6,567,136 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPRM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,528,672 - 12,702,443 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1112,634,125 - 12,702,295 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2114,770,415 - 14,819,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1pNCBI
OPRM1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1381,568,732 - 81,625,088 (+)Ensembl
ChlSab1.11381,568,295 - 81,650,005 (+)NCBI
Oprm1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247854,147,079 - 4,195,712 (-)NCBI

Position Markers
D1Rat136  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,579,208 - 43,579,402NCBIRnor6.0
Rnor_5.0144,907,605 - 44,907,799UniSTSRnor5.0
RGSC_v3.4137,647,211 - 37,647,405UniSTSRGSC3.4
RGSC_v3.4137,646,940 - 37,647,484RGDRGSC3.4
RGSC_v3.1137,649,885 - 37,650,429RGD
Celera138,929,086 - 38,929,280UniSTS
Cytogenetic Map1p11UniSTS
RH 3.4 Map1469.71RGD
RH 3.4 Map1469.71UniSTS
SHRSP x BN Map120.49RGD
SHRSP x BN Map120.49UniSTS
D1Arb7  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,486,630 - 43,486,767NCBIRnor6.0
Rnor_5.0144,815,471 - 44,815,608UniSTSRnor5.0
RGSC_v3.4137,546,625 - 37,546,763RGDRGSC3.4
RGSC_v3.4137,546,626 - 37,546,763UniSTSRGSC3.4
RGSC_v3.1137,549,570 - 37,549,708RGD
Celera138,836,062 - 38,836,199UniSTS
Cytogenetic Map1p11UniSTS
D10Chm38  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera138,913,039 - 38,913,196UniSTS
Celera1071,858,074 - 71,858,221UniSTS
Cytogenetic Map1p11UniSTS
RH94843  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,527,582 - 43,527,707NCBIRnor6.0
Rnor_5.0144,856,236 - 44,856,361UniSTSRnor5.0
RGSC_v3.4137,587,885 - 37,588,010UniSTSRGSC3.4
Celera138,876,692 - 38,876,817UniSTS
Cytogenetic Map1p11UniSTS
RH94842  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,527,553 - 43,527,679NCBIRnor6.0
Rnor_5.0144,856,207 - 44,856,333UniSTSRnor5.0
RGSC_v3.4137,587,856 - 37,587,982UniSTSRGSC3.4
Celera138,876,663 - 38,876,789UniSTS
Cytogenetic Map1p11UniSTS
U19380  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,527,551 - 43,527,654NCBIRnor6.0
Rnor_5.0144,856,205 - 44,856,308UniSTSRnor5.0
RGSC_v3.4137,587,854 - 37,587,957UniSTSRGSC3.4
Celera138,876,661 - 38,876,764UniSTS
Cytogenetic Map1p11UniSTS
RH142407  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,528,131 - 43,528,300NCBIRnor6.0
Rnor_5.0144,856,785 - 44,856,954UniSTSRnor5.0
RGSC_v3.4137,588,434 - 37,588,603UniSTSRGSC3.4
Celera138,877,241 - 38,877,410UniSTS
Cytogenetic Map1p11UniSTS
RH 3.4 Map1468.6UniSTS
BF390122  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0143,532,966 - 43,533,130NCBIRnor6.0
Rnor_5.0144,861,620 - 44,861,784UniSTSRnor5.0
RGSC_v3.4137,593,269 - 37,593,433UniSTSRGSC3.4
Celera138,882,750 - 38,882,914UniSTS
Cytogenetic Map1p11UniSTS
RH 3.4 Map1434.07UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1164407321Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)125439343579402Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)125439343579402Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)125439343579402Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)125439386904217Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1186804543724576Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1457869349578693Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1565577285706974Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11131448975844121Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11131448983657083Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11131448983657083Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11131448983657083Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11131448983657083Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11249343957493439Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11362925158629251Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11614314349547474Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11614314349547474Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12034156058000154Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12107930566079305Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12130082249454378Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12181262344409802Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12340642849547474Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12340642849547474Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12340642868406428Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123406428108057505Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)12429779978748000Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)125951907130917265Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13148945479689689Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13444911279449112Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13444911279449112Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134993530173445086Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13537750894364229Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13585416780854167Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13603316579689689Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13603316579689689Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14190724986907249Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143579208126240667Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143579208126240667Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143579208126240667Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143579208126240667Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143579208126240667Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:682
Count of miRNA genes:283
Interacting mature miRNAs:367
Transcripts:ENSRNOT00000024682, ENSRNOT00000045144, ENSRNOT00000051837
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 4 4 58 2
Below cutoff 1 6 15 3 15 3 2 2 8 10 11 11 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001038597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001038599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001038600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001038601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_027877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07001431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07001432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07001433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01002738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY225402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY225403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY309000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY309002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY309003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY309004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ680043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU024650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU024651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU024652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU340244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU340245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU340246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ041289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ699463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L13069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L20684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U02083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000024682   ⟹   ENSRNOP00000024682
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,704,948 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000045144
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,870 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000051837   ⟹   ENSRNOP00000051290
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,527,605 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077168
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,508,870 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079390
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,527,605 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079628   ⟹   ENSRNOP00000072626
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,595 - 43,703,276 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082455
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,867 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083308   ⟹   ENSRNOP00000074079
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,597 - 43,700,633 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084099
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,418 - 43,527,716 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,562 - 43,510,853 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,803 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088253
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,503,264 - 43,527,549 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088389
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,803 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089326
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,562 - 43,518,746 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089428
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,517,148 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,867 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091832
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,510,657 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092034   ⟹   ENSRNOP00000068988
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,475,589 - 43,703,276 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092385
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,867 - 43,527,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092578
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,454,803 - 43,527,693 (+)Ensembl
RefSeq Acc Id: NM_001038597   ⟹   NP_001033686
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,508,870 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 38,857,976 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001038599   ⟹   NP_001033688
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,517,148 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 38,866,254 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001038600   ⟹   NP_001033689
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,704,948 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 39,057,359 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001038601   ⟹   NP_001033690
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,703,276 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 39,055,687 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304733   ⟹   NP_001291662
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304734   ⟹   NP_001291663
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304735   ⟹   NP_001291664
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304736   ⟹   NP_001291665
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304737   ⟹   NP_001291666
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304738   ⟹   NP_001291667
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304740   ⟹   NP_001291669
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,454,803 - 43,528,437 (+)NCBI
Celera138,804,246 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013071   ⟹   NP_037203
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,528,437 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 38,877,547 (+)NCBI
Sequence:
RefSeq Acc Id: NR_027877
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,420 - 43,703,276 (+)NCBI
Rnor_5.0144,804,181 - 45,034,145 (+)NCBI
RGSC_v3.4137,535,416 - 37,779,392 (+)RGD
Celera138,824,852 - 39,055,687 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008758731   ⟹   XP_008756953
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,236 - 43,518,871 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588827   ⟹   XP_017444316
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,526 - 43,508,632 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001033686 (Get FASTA)   NCBI Sequence Viewer  
  NP_001033688 (Get FASTA)   NCBI Sequence Viewer  
  NP_001033689 (Get FASTA)   NCBI Sequence Viewer  
  NP_001033690 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291662 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291663 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291664 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291665 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291666 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291667 (Get FASTA)   NCBI Sequence Viewer  
  NP_001291669 (Get FASTA)   NCBI Sequence Viewer  
  NP_037203 (Get FASTA)   NCBI Sequence Viewer  
  XP_008756953 (Get FASTA)   NCBI Sequence Viewer  
  XP_017444316 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16075 (Get FASTA)   NCBI Sequence Viewer  
  AAA41630 (Get FASTA)   NCBI Sequence Viewer  
  AAA41643 (Get FASTA)   NCBI Sequence Viewer  
  AAA70049 (Get FASTA)   NCBI Sequence Viewer  
  AAA79180 (Get FASTA)   NCBI Sequence Viewer  
  AAP44725 (Get FASTA)   NCBI Sequence Viewer  
  AAP44726 (Get FASTA)   NCBI Sequence Viewer  
  AAQ77384 (Get FASTA)   NCBI Sequence Viewer  
  AAQ77386 (Get FASTA)   NCBI Sequence Viewer  
  AAQ77387 (Get FASTA)   NCBI Sequence Viewer  
  AAQ77388 (Get FASTA)   NCBI Sequence Viewer  
  ABH03502 (Get FASTA)   NCBI Sequence Viewer  
  ABW84396 (Get FASTA)   NCBI Sequence Viewer  
  ABW84397 (Get FASTA)   NCBI Sequence Viewer  
  ABW84398 (Get FASTA)   NCBI Sequence Viewer  
  ACA49729 (Get FASTA)   NCBI Sequence Viewer  
  ACA49730 (Get FASTA)   NCBI Sequence Viewer  
  ACA49731 (Get FASTA)   NCBI Sequence Viewer  
  ACM90347 (Get FASTA)   NCBI Sequence Viewer  
  AET97616 (Get FASTA)   NCBI Sequence Viewer  
  BAA03852 (Get FASTA)   NCBI Sequence Viewer  
  EDL92831 (Get FASTA)   NCBI Sequence Viewer  
  EDL92832 (Get FASTA)   NCBI Sequence Viewer  
  EDL92833 (Get FASTA)   NCBI Sequence Viewer  
  EDL92834 (Get FASTA)   NCBI Sequence Viewer  
  P33535 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001033689   ⟸   NM_001038600
- Peptide Label: isoform 1C1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001033690   ⟸   NM_001038601
- Peptide Label: isoform 1C2
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_037203   ⟸   NM_013071
- Peptide Label: isoform 1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001033688   ⟸   NM_001038599
- Peptide Label: isoform 1B2
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001033686   ⟸   NM_001038597
- Peptide Label: isoform IA
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008756953   ⟸   XM_008758731
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001291666   ⟸   NM_001304737
- Peptide Label: isoform 1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291664   ⟸   NM_001304735
- Peptide Label: isoform 1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291662   ⟸   NM_001304733
- Peptide Label: isoform 1G1
- Sequence:
RefSeq Acc Id: NP_001291669   ⟸   NM_001304740
- Peptide Label: isoform 1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291667   ⟸   NM_001304738
- Peptide Label: isoform 1
- UniProtKB: P33535 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291665   ⟸   NM_001304736
- Peptide Label: isoform 1H2
- Sequence:
RefSeq Acc Id: NP_001291663   ⟸   NM_001304734
- Peptide Label: isoform 1G2
- Sequence:
RefSeq Acc Id: XP_017444316   ⟸   XM_017588827
- Peptide Label: isoform X2
- UniProtKB: A0A125U2D0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068988   ⟸   ENSRNOT00000092034
RefSeq Acc Id: ENSRNOP00000072626   ⟸   ENSRNOT00000079628
RefSeq Acc Id: ENSRNOP00000051290   ⟸   ENSRNOT00000051837
RefSeq Acc Id: ENSRNOP00000024682   ⟸   ENSRNOT00000024682
RefSeq Acc Id: ENSRNOP00000074079   ⟸   ENSRNOT00000083308
Protein Domains
G_PROTEIN_RECEP_F1_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689594
Promoter ID:EPDNEW_R119
Type:single initiation site
Name:Oprm1_1
Description:opioid receptor, mu 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,475,662 - 43,475,722EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 44835927 44835928 G A snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), DA/BklArbNsi (KNAW), ACI/EurMcwi (KNAW), ACI/N (KNAW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 43507273 43507274 G A snv ACI/EurMcwi (MCW), ACI/EurMcwi (RGD), ACI/N (MCW), COP/CrCrl (MCW & UW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 37567576 37567577 G A snv ACI/N (KNAW), ACI/EurMcwi (MCW), DA/BklArbNsi (ICAHN), ACI/EurMcwi (ICL), COP/CrCrl (MCW & UW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3234 AgrOrtholog
Ensembl Genes ENSRNOG00000018191 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024682 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000051290 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000068988 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000072626 UniProtKB/Swiss-Prot
  ENSRNOP00000074079 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024682 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000045144 ENTREZGENE
  ENSRNOT00000051837 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000077168 ENTREZGENE
  ENSRNOT00000079628 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000082455 ENTREZGENE
  ENSRNOT00000083308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000086685 ENTREZGENE
  ENSRNOT00000088389 ENTREZGENE
  ENSRNOT00000089326 ENTREZGENE
  ENSRNOT00000089428 ENTREZGENE
  ENSRNOT00000090697 ENTREZGENE
  ENSRNOT00000092034 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000092385 ENTREZGENE
  ENSRNOT00000092578 ENTREZGENE
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mu_opioid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Opioid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25601 UniProtKB/Swiss-Prot
NCBI Gene 25601 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB OPRM1 RGD
PhenoGen Oprm1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MUOPIOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OPIOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC232659
UniGene Rn.10118 ENTREZGENE
UniProt A0A125U2D0 ENTREZGENE, UniProtKB/TrEMBL
  B8K2Q4_RAT UniProtKB/TrEMBL
  G8XRH3_RAT UniProtKB/TrEMBL
  G9BXT6_RAT UniProtKB/TrEMBL
  OPRM_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q2TV20 UniProtKB/Swiss-Prot
  Q2TV21 UniProtKB/Swiss-Prot
  Q4VWM5 UniProtKB/Swiss-Prot
  Q4VWM7 UniProtKB/Swiss-Prot
  Q4VWX7 UniProtKB/Swiss-Prot
  Q4VWX8 UniProtKB/Swiss-Prot
  Q62846 UniProtKB/Swiss-Prot
  Q64064 UniProtKB/Swiss-Prot
  Q64120 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-11-06 Oprm1  opioid receptor, mu 1    Opioid receptor, mu 1  Name updated 625702 APPROVED
2002-06-10 Oprm1  Opioid receptor, mu 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in thalamus, medial habenula, hypothalamus and the caudate putamen 729179
gene_function receptor for beta-endorphin 70786
gene_process activates opioid receptors which in turn activates G-protein receptors and inhibits adenylyl cyclase 70522
gene_process plays a role in immunosuppression 70786
gene_product belongs to the G-protein coupled receptor family 70786
gene_regulation C terminal amino acid is necessary for high binding affinity; carboxamide group decreases the binding and biological activity 70522
gene_regulation mRNA level in primary neurons is increased by incubation with interleukin-4 (IL4) 70786
gene_transcript contains an IL4 response element at the -727 position in promoter region 70786