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Gene: GNAI2 (G protein subunit alpha i2) Homo sapiens
Symbol: GNAI2
Name: G protein subunit alpha i2
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in cell division and positive regulation of cell population proliferation. Localizes to several cellular components, including centrosome; midbody; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylate cyclase-inhibiting G alpha protein; GIP; GNAI2B; GTP-binding regulatory protein Gi alpha-2 chain; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i), alpha-2 subunit; H_LUCA15.1; H_LUCA16.1
Mus musculus (house mouse) : Gnai2 (guanine nucleotide binding protein (G protein), alpha inhibiting 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnai2 (G protein subunit alpha i2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnai2 (G protein subunit alpha i2)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAI2 (G protein subunit alpha i2)
Canis lupus familiaris (dog) : GNAI2 (G protein subunit alpha i2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnai2 (G protein subunit alpha i2)
Sus scrofa (pig) : GNAI2 (G protein subunit alpha i2)
Chlorocebus sabaeus (African green monkey) : GNAI2 (G protein subunit alpha i2)
Heterocephalus glaber (naked mole-rat) : Gnai2 (G protein subunit alpha i2)
more info ...
Related Pseudogenes: GNAI2P1   GNAI2P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl350,226,292 - 50,259,362 (+)EnsemblGRCh38hg38GRCh38
GRCh38350,227,068 - 50,259,362 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37350,264,120 - 50,296,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,248,651 - 50,271,790 (+)NCBINCBI36hg18NCBI36
Build 34350,248,650 - 50,271,790NCBI
Celera350,246,476 - 50,269,614 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef350,329,335 - 50,352,473 (+)NCBIHuRef
CHM1_1350,216,395 - 50,249,058 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GNAI2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730993
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.