Gene: Htr1a (5-hydroxytryptamine receptor 1A) Rattus norvegicus
Symbol: Htr1a
Name: 5-hydroxytryptamine receptor 1A
Description: ENCODES a protein that exhibits drug binding; G protein-coupled serotonin receptor activity; G-protein alpha-subunit binding; INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway; NMDA glutamate receptor clustering; positive regulation of microtubule depolymerization; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Catalepsy; Drug-Induced Dyskinesia; panic disorder; FOUND IN axon hillock; GABA-ergic synapse; integral component of presynaptic membrane; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-(3-chlorophenyl)piperazine
Type: protein-coding
Also known as: 5-HT-1A; 5-HT1A; 5-hydroxytryptamine (serotonin) receptor 1A; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5HT1A; RAT5HT1A; serotonin 1A receptor; serotonin 5-HT1A receptor; serotonin receptor 1A
Homo sapiens (human) : HTR1A (5-hydroxytryptamine receptor 1A)  HGNC  Alliance
Mus musculus (house mouse) : Htr1a (5-hydroxytryptamine (serotonin) receptor 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr1a (5-hydroxytryptamine receptor 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR1A (5-hydroxytryptamine receptor 1A)
Canis lupus familiaris (dog) : HTR1A (5-hydroxytryptamine receptor 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr1a (5-hydroxytryptamine receptor 1A)
Sus scrofa (pig) : HTR1A (5-hydroxytryptamine receptor 1A)
more info ...
Allele / Splice: Htr1am1Mcwi   Htr1am2Mcwi  
Genetic Models: FHH-Htr1am1Mcwi SS-Htr1am2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0236,246,628 - 36,247,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0255,362,662 - 55,363,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4236,434,518 - 36,435,786 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1236,354,886 - 36,356,155 (+)NCBI
Celera232,636,756 - 32,638,024 (+)NCBICelera
Cytogenetic Map2q13NCBI
RH 3.4 Map2156.5RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Htr1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2845
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE