Pigfal10 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Pigfal10 (Plasma insulin-like growth factor 1 level QTL 10) Rattus norvegicus

Symbol: Pigfal10
Name: Plasma insulin-like growth factor 1 level QTL 10
RGD ID: 8552935
Trait: blood insulin-like growth factor amount   (VT:0010479)    
Measurement Type: plasma insulin-like growth factor 1 level   (CMO:0001299)    
LOD Score: 5.7
P Value: Not Available
Variance: 9.7
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8197,997,750 - 52,997,750RGD_MAPPER_PIPELINE
mRatBN7.2191 - 36,824,771RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0191 - 38,221,845RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0194,307,913 - 49,307,913RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4191 - 37,926,274RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratdisease of metabolism  IAGP 7794844 RGD 
Pigfal10RatInsulin-Like Growth Factor I Deficiency  IAGP 7794844 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratabnormal circulating insulin-like growth factor I level  IDA 7794844 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratplasma insulin-like growth factor 1 level  IDA 7794844 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratcontrolled calorie content diet  IDA 7794844 RGD 
Pigfal10Ratfasting  IDA 7794844 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratradioimmunoassay  IDA 7794844 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10RatF344/IcoCrlf  IEA 7794844 RGD 
Pigfal10RatLOU/NimrOlaHsd  IEA 7794844 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal10Ratblood insulin-like growth factor amount  IDA 7794844 RGD 


#
Reference Title
Reference Citation
1. QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing. Marissal-Arvy N, etal., Growth Horm IGF Res. 2013 Dec;23(6):220-8. doi: 10.1016/j.ghir.2013.08.002. Epub 2013 Aug 19.


1 to 20 of 579 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
6499616Ces2fcarboxylesterase 2F19752714898Rat
1587637Ces2el1carboxylesterase 2E like 1192851637772Rat
6504334Ces2carboxylesterase 2194862656118Rat
1591847Ces2bcarboxyesterase 2B195998874359Rat
1561236Ces2c-ps2carboxylesterase 2C, pseudogene 21982298115070Rat
708353Ces2acarboxylesterase 2A19129428136480Rat
621563Ces2ecarboxylesterase 2E19157447172822Rat
41041632LOC120098497uncharacterized LOC12009849719230203269086Rat
41366346LOC120098667U6 spliceosomal RNA19232281232387Rat
1597684Speer4c1lspermatogenesis associated glutamate (E)-rich protein 4C1 like19247850253393Rat
1589596Dlg5l13discs large MAGUK scaffold protein 5 like 1319259275264071Rat
41276882LOC120098496disks large homolog 5-like19269263276114Rat
1591368Ces2jcarboxylesterase 2J19280009306152Rat
1591343Med29-ps1mediator complex subunit 29, pseudogene 119334416335034Rat
1585802Ciao2bcytosolic iron-sulfur assembly component 2B19344194346068Rat
69357RradRRAD, Ras related glycolysis inhibitor and calcium channel regulator19354184357424Rat
1311638Cdh16cadherin 1619360824371008Rat
41049030LOC120098574uncharacterized LOC12009857419368791374454Rat
628812Pdp2pyruvate dehydrogenase phosphatase catalytic subunit 219386408394068Rat
1306842Car7carbonic anhydrase 719429063438478Rat

1 to 20 of 579 rows
1 to 20 of 657 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5067662AU04761122919180937181168Ratregion
5052609RH125923019325396325627Ratregion
5080318RH14151018319334811334986Ratregion
5028665RH12592522319345814346037Ratregion
5046256RH13164821719357111357328Ratregion
5048100RH13270820719370691370898Ratregion
5505312Pdp266819390950391618Ratregion
5507085UniSTS:22444110719615513615620Ratregion
5041264RH12875721919622601622820Ratregion
5063218BE11391015019678788678938Ratregion
5043808RH13023919019687892688078Ratregion
5027371AI44977014719703982704129Ratregion
5041748RH12903621319739604739817Ratregion
5025948RH13031321319739726739939Ratregion
5040704RH12843620719815602815809Ratregion
1635800D19Got13326119997661997920Ratregion
5090203AU0496121261911225571122683Ratregion
67287D19Arb61031911225811122684Ratregion
1638502D19Got1401771912814921281669Ratregion
1636370D19Got1232051920499222050127Ratregion
1 to 20 of 657 rows

Peak: (D19Rat15)
Rat AssemblyChrPosition (strand)Source
GRCr81930,497,667 - 30,497,833 (+)Marker Load Pipeline
mRatBN7.21914,324,688 - 14,324,854 (+)MAPPER
Rnor_6.01915,721,763 - 15,721,928NCBI
Rnor_5.01926,807,831 - 26,807,996UniSTS
RGSC_v3.41915,426,091 - 15,426,458RGD
RGSC_v3.41915,426,254 - 15,426,419UniSTS
RGSC_v3.11915,430,917 - 15,431,284RGD
Celera1914,240,324 - 14,240,489UniSTS
RH 2.0 Map19253.5RGD
SHRSP x BN Map1911.2699RGD
FHH x ACI Map1916.7799RGD


1 to 10 of 34 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192481604133061905Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat

1 to 10 of 34 rows


Note Type Note Reference
qtl_general number of animals used: 93 F2 males 7794844
qtl_general software package used: ANOVA; MultiQTL software 7794844
qtl_general measurement method: 4 weeks old rats were fed SAFE-A03 chow; at 18 weeks of age they were fasted overnight, decapitated in the morning and blood samples taken; total Igf-1 level determined by radioimmunoassay 7794844
qtl_general confidence interval from 14.05-35.61 Mb 7794844