Brd7 (bromodomain containing 7) - Rat Genome Database

Name: Brd7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Brd7 (bromodomain containing 7) Rattus norvegicus

Analyze

Symbol:

Brd7

Name:

bromodomain containing 7

RGD ID:

1309891

Description:

Predicted to enable several functions, including lysine-acetylated histone binding activity; p53 binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; positive regulation of macromolecule metabolic process; and regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human BRD7 (bromodomain containing 7); PARTICIPATES IN histone modification pathway; SWI/SNF family mediated chromatin remodeling pathway; INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; cobalt dichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

bromodomain-containing protein 7; LOC361374

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BRD7 (bromodomain containing 7)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Brd7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Brd7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BRD7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BRD7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Brd7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BRD7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BRD7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Brd7 (bromodomain containing 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	BRD7 (bromodomain containing 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Brd7 (bromodomain containing 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	brd7 (bromodomain containing 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7154	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	swsn-9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	18,708,792 - 18,737,500 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	18,709,022 - 18,737,494 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	20,388,410 - 20,417,054 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	19	25,583,034 - 25,611,674 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	19	28,540,694 - 28,569,317 (+)	NCBI	Rnor_WKY
Rnor_6.0	19	19,672,780 - 19,701,484 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	19,672,856 - 19,701,484 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	30,698,139 - 30,726,814 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	20,019,637 - 20,048,264 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	20,021,019 - 20,053,087 (+)	NCBI
Celera	19	18,594,033 - 18,622,660 (+)	NCBI		Celera
Cytogenetic Map	19	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

colorectal carcinoma (ISO)

glioblastoma (ISO)

high grade glioma (ISO)

lung non-small cell carcinoma (ISO)

Lymphatic Metastasis (ISO)

malignant astrocytoma (ISO)

Malignant Granular Cell Tumor (ISO)

ovary epithelial cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

CGP 52608 (ISO)

choline (ISO)

chrysene (ISO)

clobetasol (ISO)

cobalt dichloride (EXP,ISO)

copper(II) sulfate (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP)

doxorubicin (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

indometacin (ISO)

L-methionine (ISO)

Lasiocarpine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

malathion (ISO)

methidathion (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

monocrotaline (ISO)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercetin (ISO)

tungsten (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

negative regulation of cell population proliferation (ISO)

negative regulation of DNA-templated transcription (ISO)

negative regulation of G1/S transition of mitotic cell cycle (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of histone acetylation (ISO)

regulation of mitotic cell cycle (ISO)

regulation of transcription by RNA polymerase II (IBA,ISO)

transcription initiation-coupled chromatin remodeling (ISO)

Cellular Component

cellular_component (ND)

cytosol (ISO)

nucleoplasm (ISO)

nucleus (IBA,ISO)

Molecular Function

histone binding (ISO)

lysine-acetylated histone binding (IBA,ISO)

molecular_function (ND)

p53 binding (ISO)

protein binding (ISO)

transcription cis-regulatory region binding (ISO)

transcription coactivator activity (ISO)

transcription corepressor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

SWI/SNF family mediated chromatin remodeling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	[Expression and clinical significance of bromodomain-containing protein 7 in non-small cell lung cancer].	Chen L and Yu F, Zhongguo Fei Ai Za Zhi. 2011 Oct;14(10):830-4. doi: 10.3779/j.issn.1009-3419.2011.10.11.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.	Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Tumor suppressive effects of bromodomain-containing protein 7 (BRD7) in epithelial ovarian carcinoma.	Park YA, etal., Clin Cancer Res. 2014 Feb 1;20(3):565-75. doi: 10.1158/1078-0432.CCR-13-1271. Epub 2013 Nov 6.
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	The bromodomain: From epigenome reader to druggable target.	Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28.
10.	The spectrum of SWI/SNF mutations, ubiquitous in human cancers.	Shain AH and Pollack JR, PLoS One. 2013;8(1):e55119. doi: 10.1371/journal.pone.0055119. Epub 2013 Jan 23.
11.	Disturbing miR-182 and -381 inhibits BRD7 transcription and glioma growth by directly targeting LRRC4.	Tang H, etal., PLoS One. 2014 Jan 3;9(1):e84146. doi: 10.1371/journal.pone.0084146. eCollection 2014.
12.	[Expression and SNP analysis of BRD7 gene in acute leukemia cells].	Tang XY, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008 Aug;33(8):645-50.
13.	Prognostic relevance of BRD7 expression in colorectal carcinoma.	Wu WJ, etal., Eur J Clin Invest. 2013 Feb;43(2):131-40. doi: 10.1111/eci.12024. Epub 2012 Dec 7.

Additional References at PubMed

PMID:10526152	PMID:11025449	PMID:12489984	PMID:16265664	PMID:19909775	PMID:20228809	PMID:21630459	PMID:24335282	PMID:27957794

Genomics

Comparative Map Data

Brd7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	18,708,792 - 18,737,500 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	18,709,022 - 18,737,494 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	20,388,410 - 20,417,054 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	19	25,583,034 - 25,611,674 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	19	28,540,694 - 28,569,317 (+)	NCBI	Rnor_WKY
Rnor_6.0	19	19,672,780 - 19,701,484 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	19,672,856 - 19,701,484 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	30,698,139 - 30,726,814 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	20,019,637 - 20,048,264 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	20,021,019 - 20,053,087 (+)	NCBI
Celera	19	18,594,033 - 18,622,660 (+)	NCBI		Celera
Cytogenetic Map	19	p11	NCBI

BRD7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	50,315,957 - 50,368,988 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	16	50,313,487 - 50,368,988 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	50,349,868 - 50,402,899 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	48,910,442 - 48,960,330 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	48,910,441 - 48,960,330	NCBI
Celera	16	34,867,347 - 34,917,271 (-)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI
HuRef	16	36,240,844 - 36,290,809 (-)	NCBI		HuRef
CHM1_1	16	51,760,032 - 51,809,939 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	56,113,791 - 56,166,835 (-)	NCBI		T2T-CHM13v2.0

Brd7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	89,056,522 - 89,089,249 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	89,057,667 - 89,088,822 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	88,329,894 - 88,362,252 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	88,331,039 - 88,362,194 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	90,856,210 - 90,886,090 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	91,222,416 - 91,252,261 (-)	NCBI		MGSCv36	mm8
MGSCv36	8	88,068,281 - 88,097,933 (-)	NCBI		MGSCv36	mm8
Celera	8	92,606,276 - 92,636,084 (-)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI

Brd7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955433	8,424,949 - 8,461,802 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955433	8,425,976 - 8,462,431 (-)	NCBI	ChiLan1.0	ChiLan1.0

BRD7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	16	49,462,040 - 49,510,825 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	49,463,048 - 49,514,386 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	16	30,576,449 - 30,630,409 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

BRD7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	64,966,636 - 65,002,800 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	64,966,392 - 65,002,799 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	61,538,574 - 61,580,817 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	65,511,076 - 65,553,367 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	65,511,161 - 65,551,740 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	62,334,601 - 62,376,839 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	63,354,209 - 63,396,511 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	64,242,470 - 64,284,777 (+)	NCBI		UU_Cfam_GSD_1.0

Brd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	56,156,077 - 56,194,652 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	3,393,373 - 3,433,103 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936475	3,394,423 - 3,432,998 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BRD7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	34,478,012 - 34,519,663 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	34,478,008 - 34,519,622 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

BRD7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	36,114,951 - 36,168,786 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	36,112,289 - 36,168,728 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	40,334,506 - 40,388,517 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Brd7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624757	6,294,415 - 6,335,285 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624757	6,294,559 - 6,335,401 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Brd7
30 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	128
Count of miRNA genes:	104
Interacting mature miRNAs:	112
Transcripts:	ENSRNOT00000064275
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411590	Foco7	Food consumption QTL 7	6.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	19	1	24688055	Rat
10054132	Srcrt9	Stress Responsive Cort QTL 9	2.87	0.0017	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	27355345	Rat
631678	Cm9	Cardiac mass QTL 9	4.27	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	19	1	28982497	Rat
631681	Cm12	Cardiac mass QTL 12	3.33	0.00053	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	19	1	28982497	Rat
1549847	Bss8	Bone structure and strength QTL 8	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	19	1	31963836	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	1	36824771	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	1	36824771	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	36824771	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	1	36824771	Rat
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
724565	Tcas5	Tongue tumor susceptibility QTL 5	10.04		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	19	9977753	39654489	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10323180	23069265	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
61407	Scl12	Serum cholesterol level QTL 12		0.001	blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	19	13926401	30303727	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	15114598	34521833	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat

Markers in Region

RH132127

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	19	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	42	57	41	19	41	8	11	74	35	41	11	8
Low		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000064275 ⟹ ENSRNOP00000063186

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	19	19,672,856 - 19,701,484 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086560 ⟹ ENSRNOP00000068771

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	18,709,022 - 18,737,494 (+)	Ensembl
Rnor_6.0 Ensembl	19	19,672,981 - 19,701,483 (+)	Ensembl

RefSeq Acc Id:

NM_001108440 ⟹ NP_001101910

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	18,708,873 - 18,737,500 (+)	NCBI
Rnor_6.0	19	19,672,856 - 19,701,484 (+)	NCBI
Rnor_5.0	19	30,698,139 - 30,726,814 (+)	NCBI
RGSC_v3.4	19	20,019,637 - 20,048,264 (+)	RGD
Celera	19	18,594,033 - 18,622,660 (+)	RGD

Sequence:

show sequence

CGCGCTTCTGCCGCGTCCCGCGCGTGGTCTTCTCGTGAGGGACCTCGCGCCGCCGGGCGCGAGG
ATAAAAAGAAGCGGGATCGAGACCGTGTGGAGAACGAGGCAGACAAAGATCTCCAGTGTCATGT
CCCTATAAGATTAGACTTACCTCCTGAGAAGCCTCTCACAAGCTCTTTAGCCAAACAAGAAGAA
GTAGAGCAGACACCCCTTCAGGAAGCTTTGAATCAACTCATGAGACAACTGCAAAGAAAAGACC
CAAGTGCTTTCTTTTCATTTCCTGTGACGGATTTTATTGCTCCTGGCTACTCCATGATTATTAA
ACACCCAATGGATTTTAGTACTATGAAAGAAAAGATCAAGAATAACGACTACCAGTCCATAGAA
GAGCTAAAGGATAACTTCAAGCTAATGTGTACTAATGCAATGATTTACAATAAGAGAGAATTCA
GAGCCTGAAGCAGAGTATAGACTTCATGGCAGACTTGCAGAAAACTCGGAAGCAGAAAGACAGA
GCAGATGCCTGTCAAGGTGGAGAGGACAGTGGCTGCTGGCAGAGAGAACGGGAGGACTCTGGAG
ATGCTGAAACACAGGCCTTCAAAAGCCCCACCAAGGACAATAAAAAGAAAGACAAAGATGTGCT
TGAAGACAAATGGAGAAGCAGCAACTCAGAAAGGGAGCATGAGCAGATTGAGCGCGTTGTCCAG
GAGTCGGGGGGCAAGCTAACACGGCGGCTGGCAAACTGTCAGTGTGAATTTGAAAGAAGAAAAC
CAGATGGAACAACAACACTGGGGCTTCTCCATCCTGTGGACCCCATTGTGGGAGAACCAGGCTA
CTGCCCTGTGAGACTGGGGATGACAACTGGAAGACTGCAGTCTGGAGTGAACACCCTGCAGGGG
TTCAAAGAGGATAAAAGGAACAGAGTGACCCCAGTATTATACTTGAATTATGGACCCTACAGCT
CTTATGCCCCACATTATGACTCTACATTTGCCAATATCAGCAAAGATGATTCTGACTTAATCTA
CTCAACATATGGGGAAGACTCTGACCTTCCAAACAATTTTAGCATCTCTGAGTTTTTGGCCACA
TGCCAAGATTACCCGTATGTTATGGCAGATAGTTTACTGGATGTTCTAACAAAAGGAGGACATT
CCAGGAGCCTGCAGGACTTGGACATGCCGTCACCTGAAGATGAAGGCCAGACCAGAGCACTGGA
TGTTGCCAAAGAAGCAGAGCAGGTTGCGCACATAGAGCCAGCGGGGCGTTTGGAGTCCAGCGGT
CAGGACAGGCTCACAGCACTGCAAGCAGTGACGAACTTCGGTGCTCCGGCTGAAGTCTTCGACT
CGGAAGAGGCTGAGGTGTTCCAGAGGAAGCTTGATGAAACGACAAGATTGCTCAGGGAGCTCCA
GGAGGCACAGAACGAGCGGCTGAGCACTAGGCCTCCTCCCAATATGATCTGTCTCTTGGGTCCT
TCTTACAGAGAAATGTACCTTGCTGAACAAGTGACCAATAACCTTAAAGAACTCACACAGCAAG
TGACTCCCGGCGATGTTGTAAGCATACACGGAGTCCGAAAAGCAATGGGGATTTCTGTTCCTTC
CCCCATCATGGGACACAGCCTCGTAGATTTGACAGAAGAGTGCGAAGACCCTAAGGAGACCAGT
ACTGCCGAGAGTGGGCCCGCCGCGAGCTGAACTCGCCTGCTATTTGATATATTATGTACATATT
TTTCATTCCGAACTTGGAGGTGCTTTCAGAAGATAGTAACTATTTGTAAATTGTGTTTTAATTA
AGCTTTGGAACAGTTCCTTTTAATGTTCCAAAGATTGGACTTGTATTAGGAAATAAAGCTGAAC
CTGGGACTGTGAGGC

hide sequence

RefSeq Acc Id:

XM_006255267 ⟹ XP_006255329

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	18,708,793 - 18,737,497 (+)	NCBI
Rnor_6.0	19	19,672,781 - 19,701,481 (+)	NCBI
Rnor_5.0	19	30,698,139 - 30,726,814 (+)	NCBI

Sequence:

show sequence

AGCCTGCACCCAGACCGCTTGGTGGCCCTTCTCTCCCGCCGGTGCGCCGGCCTCTCGCCCTCCC
GCCACTGCTTTCGCGCTTCTGCCGCGTCCCGCGCGTGGTCTTCTCGTGAGGGACCTCGCGCCGC
CGGGCGCGTGCCGTCCCCCTGCCTCGCGGCGCGGGGTCTCGCGGGCCCCGCTCCCGCCCTCCGC
TCGCCTGGCCCGGACCGGAAGCGGCGCCGCACGGCCTGGGCCTGGCGAAAAAGGGCGGGCTCTG
GGGCCCGGTGGGACATGGGCAAGAAGCACAAGAAGCACAAGTCGGACCGACACTTCTACGAGGA
GTACGTGGAGAAGCCCCTGAAGCTAGTCCTCAAAGTGGGAGGGAGCGAAGTCACTGAGCTCTCC
ACGGGCAGCTCCGGGCACGACTCCAGCCTCTTCGAAGACAGAAGCGACCATGACAAACACAAGG
ACAGAAAACGGAAAAAGAGGAAGAAAGGAGAGAAGCAGGCTCCGGGGGAAGAGAAGGGGAGAAA
ACGGAGGAGAGTCAAGGAGGATAAAAAGAAGCGGGATCGAGACCGTGTGGAGAACGAGGCAGAC
AAAGATCTCCAGTGTCATGTCCCTATAAGATTAGACTTACCTCCTGAGAAGCCTCTCACAAGCT
CTTTAGCCAAACAAGAAGAAGTAGAGCAGACACCCCTTCAGGAAGCTTTGAATCAACTCATGAG
ACAACTGCAAAGAAAAGACCCAAGTGCTTTCTTTTCATTTCCTGTGACGGATTTTATTGCTCCT
GGCTACTCCATGATTATTAAACACCCAATGGATTTTAGTACTATGAAAGAAAAGATCAAGAATA
ACGACTACCAGTCCATAGAAGAGCTAAAGGATAACTTCAAGCTAATGTGTACTAATGCAATGAT
TTACAATAAGCCAGAGACCATTTATTATAAAGCTGCAAAGAAGCTGTTGCACTCAGGGATGAAA
ATTCTCAGTCAGGAGAGAATTCAGAGCCTGAAGCAGAGTATAGACTTCATGGCAGACTTGCAGA
AAACTCGGAAGCAGAAAGACAGAGCAGATGCCTGTCAAGGTGGAGAGGACAGTGGCTGCTGGCA
GAGAGAACGGGAGGACTCTGGAGATGCTGAAACACAGGCCTTCAAAAGCCCCACCAAGGACAAT
AAAAAGAAAGACAAAGATGTGCTTGAAGACAAATGGAGAAGCAGCAACTCAGAAAGGGAGCATG
AGCAGATTGAGCGCGTTGTCCAGGAGTCGGGGGGCAAGCTAACACGGCGGCTGGCAAACTGTCA
GTGTGAATTTGAAAGAAGAAAACCAGATGGAACAACAACACTGGGGCTTCTCCATCCTGTGGAC
CCCATTGTGGGAGAACCAGGCTACTGCCCTGTGAGACTGGGGATGACAACTGGAAGACTGCAGT
CTGGAGTGAACACCCTGCAGGGGTTCAAAGAGGATAAAAGGAACAGAGTGACCCCAGTATTATA
CTTGAATTATGGACCCTACAGCTCTTATGCCCCACATTATGACTCTACATTTGCCAATATCAGC
AAAGATGATTCTGACTTAATCTACTCAACATATGGGGAAGACTCTGACCTTCCAAACAATTTTA
GCATCTCTGAGTTTTTGGCCACATGCCAAGATTACCCGTATGTTATGGCAGATAGTTTACTGGA
TGTTCTAACAAAAGGAGGACATTCCAGGAGCCTGCAGGACTTGGACATGCCGTCACCTGAAGAT
GAAGGCCAGACCAGAGCACTGGATGTTGCCAAAGAAGCAGAGCAGGTTGCGCACATAGAGCCAG
CGGGGCGTTTGGAGTCCAGCGGTCAGGACAGGCTCACAGCACTGCAAGCAGTGACGAACTTCGG
TGCTCCGGCTGAAGTCTTCGACTCGGAAGAGGCTGAGGTGTTCCAGAGGAAGCTTGATGAAACG
ACAAGATTGCTCAGGGAGCTCCAGGAGGCACAGAACGAGCGGCTGAGCACTAGGCCTCCTCCCA
ATATGATCTGTCTCTTGGGTCCTTCTTACAGAGAAATGTACCTTGCTGAACAAGTGACCAATAA
CCTTAAAGAACTCACACAGCAAGTGACTCCCGGCGATGTTGTAAGCATACACGGAGTCCGAAAA
GCAATGGGGATTTCTGTTCCTTCCCCCATCATGGGACACAGCCTCGTAGATTTGACAGAAGAGT
GCGAAGACCCTAAGGAGACCAGTACTGCCGAGAGTGGGCCCGCCGCGAGCTGAACTCGCCTGCT
ATTTGATATATTATGTACATATTTTTCATTCCGAACTTGGAGGTGCTTTCAGAAGATAGTAACT
ATTTGTAAATTGTGTTTTAATTAAGCTTTGGAACAGTTCCTTTTAATGTTCCAAAGATTGGACT
TGTATTAGGAAATAAAGCTGAACCTGGGACTGTGA

hide sequence

RefSeq Acc Id:

XM_006255268 ⟹ XP_006255330

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	18,708,793 - 18,737,497 (+)	NCBI
Rnor_6.0	19	19,672,780 - 19,701,481 (+)	NCBI
Rnor_5.0	19	30,698,139 - 30,726,814 (+)	NCBI

Sequence:

show sequence

CAGCCTGCACCCAGACCGCTTGGTGGCCCTTCTCTCCCGCCGGTGCGCCGGCCTCTCGCCCTCC
CGCCACTGCTTTCGCGCTTCTGCCGCGTCCCGCGCGTGGTCTTCTCGTGAGGGACCTCGCGCCG
CCGGGCGCGTGCCGTCCCCCTGCCTCGCGGCGCGGGGTCTCGCGGGCCCCGCTCCCGCCCTCCG
CTCGCCTGGCCCGGACCGGAAGCGGCGCCGCACGGCCTGGGCCTGGCGAAAAAGGGCGGGCTCT
GGGGCCCGGTGGGACATGGGCAAGAAGCACAAGAAGCACAAGTCGGACCGACACTTCTACGAGG
AGTACGTGGAGAAGCCCCTGAAGCTAGTCCTCAAAGTGGGAGGGAGCGAAGTCACTGAGCTCTC
CACGGGCAGCTCCGGGCACGACTCCAGCCTCTTCGAAGACAGAAGCGACCATGACAAACACAAG
GACAGAAAACGGAAAAAGAGGAAGAAAGGAGAGAAGCAGGCTCCGGGGGAAGAGAAGGGGAGAA
AACGGAGGAGAGTCAAGGAGGATAAAAAGAAGCGGGATCGAGACCGTGTGGAGAACGAGGCAGA
CAAAGATCTCCAGTGTCATGTCCCTATAAGATTAGACTTACCTCCTGAGAAGCCTCTCACAAGC
TCTTTAGCCAAACAAGAAGAAGTAGAGCAGACACCCCTTCAGGAAGCTTTGAATCAACTCATGA
GACAACTGCAAAGAAAAGACCCAAGTGCTTTCTTTTCATTTCCTGTGACGGATTTTATTGCTCC
TGGCTACTCCATGATTATTAAACACCCAATGGATTTTAGTACTATGAAAGAAAAGATCAAGAAT
AACGACTACCAGTCCATAGAAGAGCTAAAGGATAACTTCAAGCTAATGTGTACTAATGCAATGA
TTTACAATAAGCCAGAGACCATTTATTATAAAGCTGCAAAGAAGCTGTTGCACTCAGGGATGAA
AATTCTCAGTCAGGAGAGAATTCAGAGCCTGAAGCAGAGTATAGACTTCATGGCAGACTTGCAG
AAAACTCGGAAGCAGAAAGACAGAGCAGATGCCTGTCAAGGTGGAGAGGACAGTGGCTGCTGGC
AGAGAGAACGGGAGGACTCTGGAGATGCTGAAACACAGGCCTTCAAAAGCCCCACCAAGGACAA
TAAAAAGAAAGACAAAGATGTGCTTGAAGACAAATGGAGAAGCAGCAACTCAGAAAGGGAGCAT
GAGCAGATTGAGCGCGTTGTCCAGGAGTCGGGGGGCAAGCTAACACGGCGGCTGGCAAACTGTC
AGTGTGAATTTGAAAGAAGAAAACCAGATGGAACAACAACACTGGGGCTTCTCCATCCTGTGGA
CCCCATTGTGGGAGAACCAGGCTACTGCCCTGTGAGACTGGGGATGACAACTGGAAGACTGCAG
TCTGGAGTGAACACCCTGCAGGGGTTCAAAGAGGATAAAAGGAACAGAGTGACCCCAGTATTAT
ACTTGAATTATGGACCCTACAGCTCTTATGCCCCACATTATGACTCTACATTTGCCAATATCAG
CAAAGATGATTCTGACTTAATCTACTCAACATATGGGGAAGACTCTGACCTTCCAAACAATTTT
AGCATCTCTGAGTTTTTGGCCACATGCCAAGATTACCCGTATGTTATGGCAGATAGTTTACTGG
ATGTTCTAACAAAAGGAGGACATTCCAGGAGCCTGCAGGACTTGGACATGCCGTCACCTGAAGA
TGAAGGCCAGACCAGAGCACTGGATGTTGCCAAAGAAGCAGAGGTTGCGCACATAGAGCCAGCG
GGGCGTTTGGAGTCCAGCGGTCAGGACAGGCTCACAGCACTGCAAGCAGTGACGAACTTCGGTG
CTCCGGCTGAAGTCTTCGACTCGGAAGAGGCTGAGGTGTTCCAGAGGAAGCTTGATGAAACGAC
AAGATTGCTCAGGGAGCTCCAGGAGGCACAGAACGAGCGGCTGAGCACTAGGCCTCCTCCCAAT
ATGATCTGTCTCTTGGGTCCTTCTTACAGAGAAATGTACCTTGCTGAACAAGTGACCAATAACC
TTAAAGAACTCACACAGCAAGTGACTCCCGGCGATGTTGTAAGCATACACGGAGTCCGAAAAGC
AATGGGGATTTCTGTTCCTTCCCCCATCATGGGACACAGCCTCGTAGATTTGACAGAAGAGTGC
GAAGACCCTAAGGAGACCAGTACTGCCGAGAGTGGGCCCGCCGCGAGCTGAACTCGCCTGCTAT
TTGATATATTATGTACATATTTTTCATTCCGAACTTGGAGGTGCTTTCAGAAGATAGTAACTAT
TTGTAAATTGTGTTTTAATTAAGCTTTGGAACAGTTCCTTTTAATGTTCCAAAGATTGGACTTG
TATTAGGAAATAAAGCTGAACCTGGGACTGTGA

hide sequence

RefSeq Acc Id:

XM_039097812 ⟹ XP_038953740

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	18,708,792 - 18,737,230 (+)	NCBI

RefSeq Acc Id:

XM_039097814 ⟹ XP_038953742

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	18,708,792 - 18,737,001 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101910	(Get FASTA)	NCBI Sequence Viewer
	NP_001388171	(Get FASTA)	NCBI Sequence Viewer
	NP_001388172	(Get FASTA)	NCBI Sequence Viewer
	XP_006255329	(Get FASTA)	NCBI Sequence Viewer
	XP_006255330	(Get FASTA)	NCBI Sequence Viewer
	XP_038953740	(Get FASTA)	NCBI Sequence Viewer
	XP_038953742	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL87525	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001101910 ⟸ NM_001108440

- Sequence:

show sequence

MADLQKTRKQKDRADACQGGEDSGCWQREREDSGDAETQAFKSPTKDNKKKDKDVLEDKWRSSN
SEREHEQIERVVQESGGKLTRRLANCQCEFERRKPDGTTTLGLLHPVDPIVGEPGYCPVRLGMT
TGRLQSGVNTLQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDSD
LPNNFSISEFLATCQDYPYVMADSLLDVLTKGGHSRSLQDLDMPSPEDEGQTRALDVAKEAEQV
AHIEPAGRLESSGQDRLTALQAVTNFGAPAEVFDSEEAEVFQRKLDETTRLLRELQEAQNERLS
TRPPPNMICLLGPSYREMYLAEQVTNNLKELTQQVTPGDVVSIHGVRKAMGISVPSPIMGHSLV
DLTEECEDPKETSTAESGPAAS

hide sequence

RefSeq Acc Id:	XP_006255329 ⟸ XM_006255267
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2JTM7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKKHKKHKSDRHFYEEYVEKPLKLVLKVGGSEVTELSTGSSGHDSSLFEDRSDHDKHKDRKRK KRKKGEKQAPGEEKGRKRRRVKEDKKKRDRDRVENEADKDLQCHVPIRLDLPPEKPLTSSLAKQ EEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQS IEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQKTRKQ KDRADACQGGEDSGCWQREREDSGDAETQAFKSPTKDNKKKDKDVLEDKWRSSNSEREHEQIER VVQESGGKLTRRLANCQCEFERRKPDGTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNT LQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPNNFSISEF LATCQDYPYVMADSLLDVLTKGGHSRSLQDLDMPSPEDEGQTRALDVAKEAEQVAHIEPAGRLE SSGQDRLTALQAVTNFGAPAEVFDSEEAEVFQRKLDETTRLLRELQEAQNERLSTRPPPNMICL LGPSYREMYLAEQVTNNLKELTQQVTPGDVVSIHGVRKAMGISVPSPIMGHSLVDLTEECEDPK ETSTAESGPAAS hide sequence

RefSeq Acc Id:

XP_006255330 ⟸ XM_006255268

- Peptide Label:

isoform X4

- Sequence:

show sequence

MGKKHKKHKSDRHFYEEYVEKPLKLVLKVGGSEVTELSTGSSGHDSSLFEDRSDHDKHKDRKRK
KRKKGEKQAPGEEKGRKRRRVKEDKKKRDRDRVENEADKDLQCHVPIRLDLPPEKPLTSSLAKQ
EEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQS
IEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQKTRKQ
KDRADACQGGEDSGCWQREREDSGDAETQAFKSPTKDNKKKDKDVLEDKWRSSNSEREHEQIER
VVQESGGKLTRRLANCQCEFERRKPDGTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNT
LQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPNNFSISEF
LATCQDYPYVMADSLLDVLTKGGHSRSLQDLDMPSPEDEGQTRALDVAKEAEVAHIEPAGRLES
SGQDRLTALQAVTNFGAPAEVFDSEEAEVFQRKLDETTRLLRELQEAQNERLSTRPPPNMICLL
GPSYREMYLAEQVTNNLKELTQQVTPGDVVSIHGVRKAMGISVPSPIMGHSLVDLTEECEDPKE
TSTAESGPAAS

hide sequence

RefSeq Acc Id:

ENSRNOP00000068771 ⟸ ENSRNOT00000086560

RefSeq Acc Id:

ENSRNOP00000063186 ⟸ ENSRNOT00000064275

RefSeq Acc Id:	XP_038953740 ⟸ XM_039097812
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038953742 ⟸ XM_039097814
- Peptide Label:	isoform X2

Protein Domains

Bromo

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JTM7-F1-model_v2	AlphaFold	A0A0G2JTM7	1-652	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700977

Promoter ID:

EPDNEW_R11501

Type:

initiation region

Name:

Brd7_1

Description:

bromodomain containing 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	19,672,851 - 19,672,911	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309891	AgrOrtholog
BioCyc Gene	G2FUF-6275	BioCyc
Ensembl Genes	ENSRNOG00000014419	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000068771	ENTREZGENE
	ENSRNOP00000068771.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000086560	ENTREZGENE
	ENSRNOT00000086560.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.920.10	UniProtKB/TrEMBL
InterPro	Bromodomain	UniProtKB/TrEMBL
	Bromodomain-like_sf	UniProtKB/TrEMBL
	DUF3512	UniProtKB/TrEMBL
NCBI Gene	361374	ENTREZGENE
Pfam	Bromodomain	UniProtKB/TrEMBL
	DUF3512	UniProtKB/TrEMBL
PhenoGen	Brd7	PhenoGen
PRINTS	BROMODOMAIN	UniProtKB/TrEMBL
PROSITE	BROMODOMAIN_2	UniProtKB/TrEMBL
SMART	BROMO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47370	UniProtKB/TrEMBL
UniProt	A0A0G2JTM7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Brd7	bromodomain containing 7	Brd7_predicted	bromodomain containing 7 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Brd7_predicted	bromodomain containing 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

RGD Manual Annotations