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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Malignant Granular Cell Tumor | | ISO | RGD:1320478 | 8554872 | ClinVar Annotator: match by term: malignant granular cell tumor | ClinVar | | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Malignant Granular Cell Tumor | | ISO | RGD:1320478 | 8554872 | ClinVar Annotator: match by term: malignant granular cell tumor | ClinVar | | |
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# | Reference Title | Reference Citation |
1. | [Expression and clinical significance of bromodomain-containing protein 7 in non-small cell lung cancer]. | Chen L and Yu F, Zhongguo Fei Ai Za Zhi. 2011 Oct;14(10):830-4. doi: 10.3779/j.issn.1009-3419.2011.10.11. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. | Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1. |
4. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
5. | Tumor suppressive effects of bromodomain-containing protein 7 (BRD7) in epithelial ovarian carcinoma. | Park YA, etal., Clin Cancer Res. 2014 Feb 1;20(3):565-75. doi: 10.1158/1078-0432.CCR-13-1271. Epub 2013 Nov 6. |
6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
8. | Comprehensive gene review and curation | RGD comprehensive gene curation |
9. | The bromodomain: From epigenome reader to druggable target. | Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28. |
10. | The spectrum of SWI/SNF mutations, ubiquitous in human cancers. | Shain AH and Pollack JR, PLoS One. 2013;8(1):e55119. doi: 10.1371/journal.pone.0055119. Epub 2013 Jan 23. |
11. | Disturbing miR-182 and -381 inhibits BRD7 transcription and glioma growth by directly targeting LRRC4. | Tang H, etal., PLoS One. 2014 Jan 3;9(1):e84146. doi: 10.1371/journal.pone.0084146. eCollection 2014. |
12. | [Expression and SNP analysis of BRD7 gene in acute leukemia cells]. | Tang XY, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008 Aug;33(8):645-50. |
13. | Prognostic relevance of BRD7 expression in colorectal carcinoma. | Wu WJ, etal., Eur J Clin Invest. 2013 Feb;43(2):131-40. doi: 10.1111/eci.12024. Epub 2012 Dec 7. |
PMID:10526152 | PMID:11025449 | PMID:12489984 | PMID:16265664 | PMID:19909775 | PMID:20228809 | PMID:21630459 | PMID:24335282 | PMID:27957794 |
Brd7 (Rattus norvegicus - Norway rat) |
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BRD7 (Homo sapiens - human) |
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Brd7 (Mus musculus - house mouse) |
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Brd7 (Chinchilla lanigera - long-tailed chinchilla) |
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BRD7 (Pan paniscus - bonobo/pygmy chimpanzee) |
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BRD7 (Canis lupus familiaris - dog) |
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Brd7 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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BRD7 (Sus scrofa - pig) |
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BRD7 (Chlorocebus sabaeus - green monkey) |
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Brd7 (Heterocephalus glaber - naked mole-rat) |
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Variants in Brd7
30 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 42 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | 1 | ||||||||||||
Below cutoff |
RefSeq Transcripts | NM_001108440 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001401242 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_001401243 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006255267 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006255268 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008772409 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039097812 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039097814 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH474037 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JACYVU010000306 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000064275 ⟹ ENSRNOP00000063186 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000086560 ⟹ ENSRNOP00000068771 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001108440 ⟹ NP_001101910 | ||||||||||||||||||||||||
RefSeq Status: | |||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006255267 ⟹ XP_006255329 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006255268 ⟹ XP_006255330 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039097812 ⟹ XP_038953740 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039097814 ⟹ XP_038953742 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001101910 | (Get FASTA) | NCBI Sequence Viewer |
NP_001388171 | (Get FASTA) | NCBI Sequence Viewer | |
NP_001388172 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006255329 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006255330 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038953740 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038953742 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL87525 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001101910 ⟸ NM_001108440 |
- Sequence: |
RefSeq Acc Id: | XP_006255329 ⟸ XM_006255267 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A0G2JTM7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006255330 ⟸ XM_006255268 |
- Peptide Label: | isoform X4 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000068771 ⟸ ENSRNOT00000086560 |
RefSeq Acc Id: | ENSRNOP00000063186 ⟸ ENSRNOT00000064275 |
RefSeq Acc Id: | XP_038953740 ⟸ XM_039097812 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038953742 ⟸ XM_039097814 |
- Peptide Label: | isoform X2 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-A0A0G2JTM7-F1-model_v2 | AlphaFold | A0A0G2JTM7 | 1-652 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13700977 | ||||||||
Promoter ID: | EPDNEW_R11501 | ||||||||
Type: | initiation region | ||||||||
Name: | Brd7_1 | ||||||||
Description: | bromodomain containing 7 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1309891 | AgrOrtholog |
BioCyc Gene | G2FUF-6275 | BioCyc |
Ensembl Genes | ENSRNOG00000014419 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000068771 | ENTREZGENE |
ENSRNOP00000068771.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000086560 | ENTREZGENE |
ENSRNOT00000086560.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.20.920.10 | UniProtKB/TrEMBL |
InterPro | Bromodomain | UniProtKB/TrEMBL |
Bromodomain-like_sf | UniProtKB/TrEMBL | |
DUF3512 | UniProtKB/TrEMBL | |
NCBI Gene | 361374 | ENTREZGENE |
Pfam | Bromodomain | UniProtKB/TrEMBL |
DUF3512 | UniProtKB/TrEMBL | |
PhenoGen | Brd7 | PhenoGen |
PRINTS | BROMODOMAIN | UniProtKB/TrEMBL |
PROSITE | BROMODOMAIN_2 | UniProtKB/TrEMBL |
SMART | BROMO | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF47370 | UniProtKB/TrEMBL |
UniProt | A0A0G2JTM7 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-04-30 | Brd7 | bromodomain containing 7 | Brd7_predicted | bromodomain containing 7 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Brd7_predicted | bromodomain containing 7 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |