Slc10a7 (solute carrier family 10, member 7) - Rat Genome Database
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Gene: Slc10a7 (solute carrier family 10, member 7) Rattus norvegicus
Analyze
Symbol: Slc10a7
Name: solute carrier family 10, member 7
RGD ID: 1564388
Description: Predicted to have bile acid transmembrane transporter activity. Predicted to be involved in several processes, including cellular calcium ion homeostasis; glycoprotein transport; and heparin biosynthetic process. Localizes to endoplasmic reticulum and intrinsic component of plasma membrane. Orthologous to human SLC10A7 (solute carrier family 10 member 7); INTERACTS WITH 2,5-hexanedione; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Na(+)/bile acid cotransporter 7; P7; sodium/bile acid cotransporter 7; solute carrier family 10 (sodium/bile acid cotransporter family), member 7; solute carrier family 10 (sodium/bile acid cotransporter family), member 7-like; solute carrier family 10 member 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21929,183,143 - 29,407,470 (-)NCBI
Rnor_6.0 Ensembl1932,855,343 - 33,080,998 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01932,857,984 - 33,081,359 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01943,751,269 - 43,972,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,029,928 - 31,074,346 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1928,685,274 - 28,905,878 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:22029531   PMID:29878199   PMID:30082715  


Genomics

Comparative Map Data
Slc10a7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21929,183,143 - 29,407,470 (-)NCBI
Rnor_6.0 Ensembl1932,855,343 - 33,080,998 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01932,857,984 - 33,081,359 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01943,751,269 - 43,972,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,029,928 - 31,074,346 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1928,685,274 - 28,905,878 (-)NCBICelera
Cytogenetic Map19q11NCBI
SLC10A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4146,253,975 - 146,521,964 (-)EnsemblGRCh38hg38GRCh38
GRCh384146,253,981 - 146,522,351 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374147,175,133 - 147,443,092 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh374147,175,137 - 147,443,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,395,627 - 147,662,535 (-)NCBINCBI36hg18NCBI36
Celera4144,494,604 - 144,763,675 (-)NCBI
Cytogenetic Map4q31.22NCBI
HuRef4142,895,956 - 143,170,355 (-)NCBIHuRef
CHM1_14147,152,427 - 147,420,419 (-)NCBICHM1_1
Slc10a7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,235,957 - 79,460,641 (+)NCBIGRCm39mm39
GRCm38878,509,323 - 78,734,012 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,509,346 - 78,734,003 (+)EnsemblGRCm38mm10GRCm38
MGSCv37881,033,234 - 81,257,904 (+)NCBIGRCm37mm9NCBIm37
MGSCv36881,405,647 - 81,627,710 (+)NCBImm8
Celera882,785,960 - 83,011,085 (+)NCBICelera
Cytogenetic Map8C1NCBI
Slc10a7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554281,999,280 - 2,250,234 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554281,999,341 - 2,250,201 (-)NCBIChiLan1.0ChiLan1.0
SLC10A7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14150,249,964 - 150,511,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4150,251,966 - 150,510,812 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04138,592,266 - 138,857,833 (-)NCBIMhudiblu_PPA_v0panPan3
SLC10A7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1544,720,629 - 44,957,495 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11544,718,085 - 44,957,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc10a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365352,792,576 - 3,038,504 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC10A7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl882,115,056 - 82,355,655 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1882,115,057 - 82,355,660 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2887,489,210 - 87,651,904 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2887,282,708 - 87,303,582 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC10A7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1792,798,344 - 93,052,737 (-)NCBI
Slc10a7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248535,110,729 - 5,365,312 (-)NCBI

Position Markers
D19Rat29  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01932,994,392 - 32,994,577NCBIRnor6.0
Rnor_5.01943,887,287 - 43,887,472UniSTSRnor5.0
RGSC_v3.41931,224,173 - 31,224,359RGDRGSC3.4
RGSC_v3.41931,224,174 - 31,224,359UniSTSRGSC3.4
RGSC_v3.11931,228,888 - 31,229,347RGD
Celera1928,821,821 - 28,822,006UniSTS
RH 2.0 Map19345.1RGD
SHRSP x BN Map1922.4798RGD
Cytogenetic Map19q11UniSTS
D19Got116  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01933,079,592 - 33,079,732NCBIRnor6.0
Rnor_5.01943,971,787 - 43,971,927UniSTSRnor5.0
RGSC_v3.41931,308,436 - 31,308,576UniSTSRGSC3.4
Celera1928,904,698 - 28,904,838UniSTS
Cytogenetic Map19q11UniSTS
RH133626  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01932,897,972 - 32,898,179NCBIRnor6.0
Rnor_5.01943,791,257 - 43,791,464UniSTSRnor5.0
RGSC_v3.41931,128,443 - 31,128,650UniSTSRGSC3.4
RGSC_v3.41931,033,494 - 31,033,701UniSTSRGSC3.4
Celera1928,725,491 - 28,725,698UniSTS
RH 3.4 Map19222.29UniSTS
Cytogenetic Map19q11UniSTS
AW534219  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01933,006,738 - 33,006,943NCBIRnor6.0
Rnor_5.01943,898,933 - 43,899,138UniSTSRnor5.0
RGSC_v3.41931,237,178 - 31,237,383UniSTSRGSC3.4
Celera1928,833,994 - 28,834,199UniSTS
RH 3.4 Map19221.3UniSTS
Cytogenetic Map19q11UniSTS
AU047602  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.010647,530 - 648,128NCBIRnor6.0
Rnor_6.01933,035,230 - 33,035,459NCBIRnor6.0
Rnor_5.01943,927,425 - 43,927,654UniSTSRnor5.0
Rnor_5.01011,330,226 - 11,330,824UniSTSRnor5.0
RGSC_v3.41931,264,701 - 31,264,930UniSTSRGSC3.4
RGSC_v3.410550,874 - 551,472UniSTSRGSC3.4
Celera1928,861,530 - 28,861,755UniSTS
Celera1011,221,486 - 11,222,084UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map10q11UniSTS
RH137673  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01932,889,304 - 32,889,518NCBIRnor6.0
Rnor_5.01943,782,589 - 43,782,803UniSTSRnor5.0
RGSC_v3.41931,042,155 - 31,042,369UniSTSRGSC3.4
Celera1928,716,823 - 28,717,037UniSTS
Cytogenetic Map19q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19138221845Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19138221845Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19138221845Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19138221845Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19104464846044648Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19195770746957707Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19243296347217667Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)19370183548701835Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)19370183548701835Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19500757143907843Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19650676160220581Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19807254547318201Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191130392747879277Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191529452433991703Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191593952838798459Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191702800352538299Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192445572643907843Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192445762737140233Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192481825762275575Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)193119430141686140Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)193119430141686140Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)193119430141686140Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)193299439262275575Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:137
Count of miRNA genes:109
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000015985
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 20 14 8 12 8 24 20 33 11
Low 23 43 33 7 33 8 11 50 15 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015985   ⟹   ENSRNOP00000015985
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1932,855,343 - 33,080,998 (-)Ensembl
RefSeq Acc Id: NM_001010948   ⟹   NP_001010948
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21929,185,558 - 29,407,241 (-)NCBI
Rnor_6.01932,857,984 - 33,080,772 (-)NCBI
Rnor_5.01943,751,269 - 43,972,967 (-)NCBI
RGSC_v3.41931,029,928 - 31,074,346 (+)RGD
Celera1928,685,274 - 28,905,878 (-)RGD
Sequence:
RefSeq Acc Id: XM_017601213   ⟹   XP_017456702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01932,860,721 - 33,081,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601214   ⟹   XP_017456703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01932,930,448 - 33,081,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601215   ⟹   XP_017456704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01933,018,303 - 33,081,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097585   ⟹   XP_038953513
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21929,183,143 - 29,407,470 (-)NCBI
RefSeq Acc Id: XM_039097586   ⟹   XP_038953514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21929,183,143 - 29,407,470 (-)NCBI
RefSeq Acc Id: XR_001842204
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01933,018,303 - 33,081,359 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005496630
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21929,183,143 - 29,407,470 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001010948 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953513 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953514 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAV80712 (Get FASTA)   NCBI Sequence Viewer  
  EDL92322 (Get FASTA)   NCBI Sequence Viewer  
  Q5PT50 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001010948   ⟸   NM_001010948
- UniProtKB: Q5PT50 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456702   ⟸   XM_017601213
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456703   ⟸   XM_017601214
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456704   ⟸   XM_017601215
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000015985   ⟸   ENSRNOT00000015985
RefSeq Acc Id: XP_038953514   ⟸   XM_039097586
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953513   ⟸   XM_039097585
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701055
Promoter ID:EPDNEW_R11578
Type:initiation region
Name:Slc10a7_1
Description:solute carrier family 10, member 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01933,080,995 - 33,081,055EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564388 AgrOrtholog
Ensembl Genes ENSRNOG00000011991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000015985 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015985 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1530.20 UniProtKB/Swiss-Prot
InterPro Na+/solute_symporter_sf UniProtKB/Swiss-Prot
  Put_Na-Bile_cotransptr UniProtKB/Swiss-Prot
KEGG Report rno:291942 UniProtKB/Swiss-Prot
NCBI Gene 291942 ENTREZGENE
PANTHER PTHR18640 UniProtKB/Swiss-Prot
Pfam SBF_like UniProtKB/Swiss-Prot
PhenoGen Slc10a7 PhenoGen
PIRSF UCP026166 UniProtKB/Swiss-Prot
UniProt NTCP7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-02 Slc10a7  solute carrier family 10, member 7  Slc10a7  solute carrier family 10 (sodium/bile acid cotransporter family), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Slc10a7  solute carrier family 10 (sodium/bile acid cotransporter family), member 7  LOC100361333  solute carrier family 10 (sodium/bile acid cotransporter family), member 7-like  Data Merged 1643240 APPROVED
2010-05-05 LOC100361333  solute carrier family 10 (sodium/bile acid cotransporter family), member 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-06 Slc10a7  solute carrier family 10 (sodium/bile acid cotransporter family), member 7  P7  P7 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 P7  P7 protein      Symbol and Name status set to provisional 70820 PROVISIONAL