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Gene: Nfat5 (nuclear factor of activated T-cells 5) Rattus norvegicus
Symbol: Nfat5
Name: nuclear factor of activated T-cells 5
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in response to osmotic stress. Localizes to cytoplasm and nucleus. Orthologous to human NFAT5 (nuclear factor of activated T cells 5); PARTICIPATES IN B cell receptor signaling pathway; T cell receptor signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 5-azaorotic acid.
Type: protein-coding
Also known as: NF-AT5; Nfat; nuclear factor of activated T-cells 5, tonicity-responsive; T-cell transcription factor NFAT5; TonEBP
Homo sapiens (human) : NFAT5 (nuclear factor of activated T cells 5)  HGNC  Alliance
Mus musculus (house mouse) : Nfat5 (nuclear factor of activated T cells 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfat5 (nuclear factor of activated T cells 5)
Pan paniscus (bonobo/pygmy chimpanzee) : NFAT5 (nuclear factor of activated T cells 5)
Canis lupus familiaris (dog) : NFAT5 (nuclear factor of activated T cells 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfat5 (nuclear factor of activated T cells 5)
Sus scrofa (pig) : NFAT5 (nuclear factor of activated T cells 5)
Chlorocebus sabaeus (African green monkey) : NFAT5 (nuclear factor of activated T cells 5)
Heterocephalus glaber (naked mole-rat) : Nfat5 (nuclear factor of activated T cells 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01938,446,059 - 38,533,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,446,059 - 38,533,735 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01949,320,570 - 49,403,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01950,363,699 - 50,398,311 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41937,154,326 - 37,242,191 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11937,093,773 - 37,238,503 (+)NCBI
Celera1934,621,583 - 34,708,117 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nfat5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309142
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.