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Gene: Nfat5 (nuclear factor of activated T-cells 5) Rattus norvegicus
Symbol: Nfat5
Name: nuclear factor of activated T-cells 5
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Involved in response to osmotic stress. Localizes to the cytoplasm and nucleus. Orthologous to human NFAT5 (nuclear factor of activated T cells 5); PARTICIPATES IN B cell receptor signaling pathway; T cell receptor signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
Also known as: NF-AT5; Nfat; nuclear factor of activated T-cells 5, tonicity-responsive; T-cell transcription factor NFAT5; TonEBP
Homo sapiens (human) : NFAT5 (nuclear factor of activated T cells 5)  HGNC  Alliance
Mus musculus (house mouse) : Nfat5 (nuclear factor of activated T cells 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfat5 (nuclear factor of activated T cells 5)
Pan paniscus (bonobo/pygmy chimpanzee) : NFAT5 (nuclear factor of activated T cells 5)
Canis lupus familiaris (dog) : NFAT5 (nuclear factor of activated T cells 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfat5 (nuclear factor of activated T cells 5)
Sus scrofa (pig) : NFAT5 (nuclear factor of activated T cells 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01938,446,059 - 38,533,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01950,363,699 - 50,398,311 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01949,320,570 - 49,403,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41937,154,326 - 37,242,191 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11937,093,773 - 37,238,503 (+)NCBI
Celera1934,621,583 - 34,708,117 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nfat5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309142
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-06-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.