Ednra (endothelin receptor type A) - Rat Genome Database

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Gene: Ednra (endothelin receptor type A) Rattus norvegicus
Analyze
Symbol: Ednra
Name: endothelin receptor type A
RGD ID: 2535
Description: Exhibits endothelin receptor activity. Involved in several processes, including cellular response to mechanical stimulus; positive regulation of cytosolic calcium ion concentration; and positive regulation of response to external stimulus. Localizes to T-tubule and nuclear membrane. Colocalizes with membrane raft. Used to study hypertension; myocardial infarction; portal hypertension; pulmonary emphysema; and pulmonary hypertension. Biomarker of several diseases, including hyperhomocysteinemia; impotence; obstructive sleep apnea; renal fibrosis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A); PARTICIPATES IN endothelin signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH (R)-noradrenaline; 11-deoxycorticosterone; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ENDOR; endothelin A receptor; endothelin-1 receptor; endothelin-1 receptor-like; ET-A; ET-AR; Eta; LOC100366209; RATENDOR; RGD1559432
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: QTLs:   Scl12  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21930,233,540 - 30,303,727 (+)NCBI
Rnor_6.0 Ensembl1933,928,356 - 33,991,703 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01933,928,356 - 33,991,703 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,812,252 - 44,874,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,042,366 - 32,108,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11932,051,058 - 32,110,066 (+)NCBI
Celera1929,719,589 - 29,778,843 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
11-deoxycorticosterone  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-naphthylamine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
aldehydo-D-glucose  (ISO)
aldosterone  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ambrisentan  (ISO)
aminoguanidine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antirheumatic drug  (ISO)
apocynin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
aspartame  (ISO)
atorvastatin calcium  (EXP)
atrasentan  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bosentan  (EXP,ISO)
BQ 123  (EXP,ISO)
BQ 485  (EXP)
calcium atom  (EXP)
calcium(0)  (EXP)
carbon nanotube  (ISO)
carmustine  (ISO)
celecoxib  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
cocaine  (EXP,ISO)
cycloheximide  (EXP)
cyclosporin A  (EXP)
D-glucose  (ISO)
daunorubicin  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl malate  (ISO)
dimethyl sulfoxide  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enrasentan  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fluvastatin  (EXP)
folic acid  (ISO)
fructose  (EXP,ISO)
fulvestrant  (ISO)
furan  (EXP)
glucose  (ISO)
isoprenaline  (EXP,ISO)
isoquinoline-1,5-diol  (EXP)
losartan  (EXP)
Magnolol  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mifepristone  (EXP)
monocrotaline  (EXP)
nicotine  (ISO)
nitrofen  (EXP,ISO)
ouabain  (EXP)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phosphoramidon  (EXP)
pirinixic acid  (ISO)
potassium chloride  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
quartz  (ISO)
raloxifene  (ISO)
reactive oxygen species  (EXP)
rebaudioside A  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium chloride  (EXP,ISO)
steviol  (ISO)
stevioside  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
superoxide  (EXP)
tacrolimus hydrate  (EXP)
tamoxifen  (ISO)
Tanshinone I  (EXP)
telmisartan  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
valsartan  (EXP)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (IEA,ISO)
aging  (IEP)
artery smooth muscle contraction  (IEA,ISO)
branching involved in blood vessel morphogenesis  (IEA,ISO)
cellular response to mechanical stimulus  (IMP)
endothelin receptor signaling pathway  (IEA)
enteric nervous system development  (IEA)
fibroblast proliferation  (IMP)
glomerular filtration  (IMP)
head development  (IEA,ISO)
heart development  (IEA,ISO)
histamine secretion  (IMP)
in utero embryonic development  (IEA,ISO)
maternal process involved in parturition  (IEP)
negative regulation of apoptotic process  (IMP)
neural crest cell development  (IEA,ISO)
penile erection  (IMP)
positive regulation of calcium ion transport  (IMP)
positive regulation of cell population proliferation  (IMP)
positive regulation of cytosolic calcium ion concentration  (IDA)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (IMP)
positive regulation of ERK1 and ERK2 cascade  (IMP)
positive regulation of inflammatory response  (IMP)
positive regulation of kidney development  (IMP)
positive regulation of neutrophil chemotaxis  (IMP)
positive regulation of odontogenesis  (IMP)
positive regulation of protein phosphorylation  (IMP)
positive regulation of release of sequestered calcium ion into cytosol  (IMP)
protein kinase C-activating G protein-coupled receptor signaling pathway  (IMP)
regulation of blood pressure  (IEA,ISO)
regulation of epithelial cell proliferation  (IMP)
regulation of glucose transmembrane transport  (IEA,ISO)
respiratory gaseous exchange by respiratory system  (IEA,ISO)
response to hypoxia  (IEA,ISO)
response to lipopolysaccharide  (IMP)
response to morphine  (IMP)
response to organic cyclic compound  (IEP)
Rho protein signal transduction  (IMP)
sensory perception of pain  (IMP)
smooth muscle cell proliferation  (IMP)
vasoconstriction  (IEA,IMP,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
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25. Girsh E and Dekel N, Mol Reprod Dev 2002 Sep;63(1):71-8.
26. GOA data from the GO Consortium
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39. MGD data from the GO Consortium
40. Mitchell D, etal., Microvasc Res. 2002 Jul;64(1):179-85.
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43. NCBI rat LocusLink and RefSeq merged data July 26, 2002
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45. Nishida M, etal., J Cardiovasc Pharmacol. 2004 Aug;44(2):187-91.
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47. Oku H, etal., Curr Eye Res. 2008 Jul;33(7):611-20.
48. OMIM Disease Annotation Pipeline
49. Perry MG, etal., Am J Physiol Heart Circ Physiol 2001 Dec;281(6):H2680-6.
50. Pipeline to import KEGG annotations from KEGG into RGD
51. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
52. Plusczyk T, etal., Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G145-53.
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55. Reinehr R, etal., Hepatology 2002 Oct;36(4 Pt 1):861-73.
56. RGD automated data pipeline
57. RGD automated import pipeline for gene-chemical interactions
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Additional References at PubMed
PMID:1312429   PMID:8982507   PMID:9449664   PMID:9826706   PMID:10626068   PMID:11546805   PMID:11882629   PMID:11897624   PMID:11910302   PMID:12464391   PMID:12668144   PMID:12686728  
PMID:12851419   PMID:14993193   PMID:15306564   PMID:15327783   PMID:15344879   PMID:15563533   PMID:15585964   PMID:15664398   PMID:15668985   PMID:15838253   PMID:15838256   PMID:15838268  
PMID:15838271   PMID:15838315   PMID:15838319   PMID:15838321   PMID:15838330   PMID:15838346   PMID:15838359   PMID:15838360   PMID:15838361   PMID:15838363   PMID:15915003   PMID:15928212  
PMID:16463654   PMID:16712977   PMID:16736156   PMID:16763077   PMID:16947426   PMID:17060503   PMID:17312275   PMID:17333248   PMID:17379848   PMID:17400719   PMID:17495482   PMID:17626731  
PMID:17639881   PMID:17670915   PMID:17892519   PMID:18205269   PMID:18281380   PMID:18287215   PMID:18424628   PMID:18462720   PMID:18469849   PMID:18515645   PMID:18518881   PMID:18524860  
PMID:18567602   PMID:18823320   PMID:19029977   PMID:19104001   PMID:19157542   PMID:19628575   PMID:19748906   PMID:20307649   PMID:20450830   PMID:20628427   PMID:20844020   PMID:21801590  
PMID:21801594   PMID:21801595   PMID:22258095   PMID:22365956   PMID:22406300   PMID:22407503   PMID:22569294   PMID:22952915   PMID:23047940   PMID:23351051   PMID:23396520   PMID:23436727  
PMID:23946290   PMID:24144054   PMID:24157978   PMID:24449761   PMID:24486390   PMID:24582810   PMID:24636620   PMID:24815227   PMID:24918345   PMID:25088996   PMID:25091502   PMID:25255392  
PMID:25891848   PMID:26459423   PMID:26528589   PMID:26776836   PMID:27697218   PMID:27997891   PMID:28012855   PMID:28412414   PMID:28579512   PMID:28757442   PMID:29329779   PMID:29360807  
PMID:31075232   PMID:31398465   PMID:32023824   PMID:33127751  


Genomics

Comparative Map Data
Ednra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21930,233,540 - 30,303,727 (+)NCBI
Rnor_6.0 Ensembl1933,928,356 - 33,991,703 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01933,928,356 - 33,991,703 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,812,252 - 44,874,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,042,366 - 32,108,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11932,051,058 - 32,110,066 (+)NCBI
Celera1929,719,589 - 29,778,843 (+)NCBICelera
Cytogenetic Map19q11NCBI
EDNRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4147,480,917 - 147,544,954 (+)EnsemblGRCh38hg38GRCh38
GRCh384147,481,097 - 147,544,954 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374148,402,249 - 148,466,106 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364148,621,575 - 148,685,555 (+)NCBINCBI36hg18NCBI36
Build 344148,759,734 - 148,823,710NCBI
Celera4145,723,204 - 145,787,202 (+)NCBI
Cytogenetic Map4q31.22-q31.23NCBI
HuRef4144,129,326 - 144,193,179 (+)NCBIHuRef
CHM1_14148,380,418 - 148,444,465 (+)NCBICHM1_1
Ednra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39878,389,658 - 78,451,081 (-)NCBIGRCm39mm39
GRCm39 Ensembl878,389,660 - 78,451,093 (-)Ensembl
GRCm38877,663,029 - 77,724,452 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl877,663,031 - 77,724,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv37880,186,928 - 80,248,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv36880,559,140 - 80,620,420 (-)NCBImm8
Celera881,946,457 - 82,007,225 (-)NCBICelera
Cytogenetic Map8C1NCBI
Ednra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554283,062,303 - 3,114,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554283,062,303 - 3,114,761 (+)NCBIChiLan1.0ChiLan1.0
EDNRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14151,476,353 - 151,536,497 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4151,476,356 - 151,536,497 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04139,815,336 - 139,879,600 (+)NCBIMhudiblu_PPA_v0panPan3
EDNRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11545,823,472 - 45,878,527 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1545,823,560 - 45,876,463 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1546,219,878 - 46,270,714 (+)NCBI
ROS_Cfam_1.01546,496,528 - 46,553,179 (+)NCBI
UMICH_Zoey_3.11545,768,959 - 45,819,737 (+)NCBI
UNSW_CanFamBas_1.01545,864,678 - 45,915,481 (+)NCBI
UU_Cfam_GSD_1.01546,175,034 - 46,225,816 (+)NCBI
Ednra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530144,512,782 - 44,568,451 (-)NCBI
SpeTri2.0NW_0049365351,950,117 - 2,005,786 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDNRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl881,209,327 - 81,276,853 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1881,210,750 - 81,279,053 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2886,293,177 - 86,319,721 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EDNRA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1793,980,983 - 94,043,863 (+)NCBI
ChlSab1.1 Ensembl793,985,797 - 94,042,296 (+)Ensembl
Vero_WHO_p1.0NW_02366603773,678,428 - 73,748,330 (+)NCBI
Ednra
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248536,298,406 - 6,362,353 (+)NCBI

Position Markers
D19Mco2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01944,873,858 - 44,874,084NCBIRnor5.0
RGSC_v3.41932,107,108 - 32,107,333RGDRGSC3.4
RGSC_v3.11932,111,934 - 32,112,159RGD
Cytogenetic Map19q11UniSTS
RH127903  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,296,755 - 30,296,970 (+)MAPPER
Rnor_6.01933,991,410 - 33,991,624NCBIRnor6.0
Rnor_5.01944,874,611 - 44,874,825UniSTSRnor5.0
RGSC_v3.41932,107,860 - 32,108,074UniSTSRGSC3.4
Celera1929,778,550 - 29,778,764UniSTS
Cytogenetic Map19q11UniSTS
RH141089  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,295,676 - 30,295,891 (+)MAPPER
Rnor_6.01933,990,331 - 33,990,545NCBIRnor6.0
Rnor_5.01944,873,532 - 44,873,746UniSTSRnor5.0
RGSC_v3.41932,106,781 - 32,106,995UniSTSRGSC3.4
Celera1929,777,471 - 29,777,685UniSTS
RH 3.4 Map19231.2UniSTS
Cytogenetic Map19q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19138221845Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19138221845Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19138221845Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19138221845Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19104464846044648Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19195770746957707Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19243296347217667Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)19370183548701835Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)19370183548701835Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19500757143907843Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19650676160220581Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19807254547318201Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191130392747879277Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191529452433991703Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191593952838798459Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191702800352538299Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192445572643907843Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192445762737140233Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192481825762275575Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)193119430141686140Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)193119430141686140Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)193119430141686140Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)193299439262275575Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:386
Count of miRNA genes:211
Interacting mature miRNAs:276
Transcripts:ENSRNOT00000058162
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 37 6 20 37 11
Low 3 6 57 41 19 41 8 11 68 15 4 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000058162   ⟹   ENSRNOP00000054967
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,928,356 - 33,991,703 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078395   ⟹   ENSRNOP00000072294
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,932,532 - 33,988,729 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078701   ⟹   ENSRNOP00000069839
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,932,532 - 33,988,729 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080095   ⟹   ENSRNOP00000071866
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,931,719 - 33,988,877 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080317   ⟹   ENSRNOP00000071667
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,932,558 - 33,988,196 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091985   ⟹   ENSRNOP00000073963
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1933,932,532 - 33,988,729 (+)Ensembl
RefSeq Acc Id: NM_012550   ⟹   NP_036682
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,233,692 - 30,297,049 (+)NCBI
Rnor_6.01933,928,356 - 33,991,703 (+)NCBI
Rnor_5.01944,812,252 - 44,874,904 (+)NCBI
RGSC_v3.41932,042,366 - 32,108,153 (+)RGD
Celera1929,719,589 - 29,778,843 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772471   ⟹   XP_008770693
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01933,928,775 - 33,991,703 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772472   ⟹   XP_008770694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01933,960,977 - 33,991,703 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097468   ⟹   XP_038953396
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,233,540 - 30,293,865 (+)NCBI
RefSeq Acc Id: XR_005496613
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,233,543 - 30,303,727 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036682   ⟸   NM_012550
- Peptide Label: precursor
- UniProtKB: P26684 (UniProtKB/Swiss-Prot),   A0A0G2JSX5 (UniProtKB/TrEMBL),   A1Y2B8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770693   ⟸   XM_008772471
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008770694   ⟸   XM_008772472
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000071667   ⟸   ENSRNOT00000080317
RefSeq Acc Id: ENSRNOP00000071866   ⟸   ENSRNOT00000080095
RefSeq Acc Id: ENSRNOP00000072294   ⟸   ENSRNOT00000078395
RefSeq Acc Id: ENSRNOP00000054967   ⟸   ENSRNOT00000058162
RefSeq Acc Id: ENSRNOP00000073963   ⟸   ENSRNOT00000091985
RefSeq Acc Id: ENSRNOP00000069839   ⟸   ENSRNOT00000078701
RefSeq Acc Id: XP_038953396   ⟸   XM_039097468
- Peptide Label: isoform X1
Protein Domains
G_PROTEIN_RECEP_F1_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2535 AgrOrtholog
Ensembl Genes ENSRNOG00000012721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000054967 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069839 UniProtKB/TrEMBL
  ENSRNOP00000071667 UniProtKB/TrEMBL
  ENSRNOP00000071866 UniProtKB/TrEMBL
  ENSRNOP00000072294 UniProtKB/TrEMBL
  ENSRNOP00000073963 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058162 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000078395 UniProtKB/TrEMBL
  ENSRNOT00000078701 UniProtKB/TrEMBL
  ENSRNOT00000080095 UniProtKB/TrEMBL
  ENSRNOT00000080317 UniProtKB/TrEMBL
  ENSRNOT00000091985 UniProtKB/TrEMBL
InterPro Endthln_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETA_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24326 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24326 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ednra PhenoGen
PRINTS ENDOTHELINAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENDOTHELINR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC215722
UniProt A0A0G2JSX5 ENTREZGENE, UniProtKB/TrEMBL
  A1Y2B8 ENTREZGENE, UniProtKB/TrEMBL
  A1Y2R7_RAT UniProtKB/TrEMBL
  A1Y2R8_RAT UniProtKB/TrEMBL
  A1Y2R9_RAT UniProtKB/TrEMBL
  EDNRA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-29 Ednra  endothelin receptor type A  RGD1559432  RGD1559432  Data Merged 737654 PROVISIONAL
2013-03-29 Ednra  endothelin receptor type A  LOC100366209  endothelin-1 receptor-like  Data Merged 737654 PROVISIONAL
2010-05-06 LOC100366209  endothelin-1 receptor-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1559432  RGD1559432   RGD1559432_predicted  RGD1559432 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559432_predicted  RGD1559432 (predicted)  LOC498937  LOC498937  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498937  LOC498937      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ednra  Endothelin receptor type A      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression not expressed in Spontaneously hypertensive rat hearts but was expressed in salt-hypertensive sensitive and resistant rats fed a high-salt diet 1358986
gene_expression expressed in vascular and nonvascular tissues 628459
gene_expression expressed in vascular and nonvascular tissues 628515
gene_expression expressed in vascular and nonvascular tissues 628516
gene_product member of the endothelian family 628516