Arhgap10 (Rho GTPase activating protein 10) - Rat Genome Database

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Gene: Arhgap10 (Rho GTPase activating protein 10) Rattus norvegicus
Analyze
Symbol: Arhgap10
Name: Rho GTPase activating protein 10
RGD ID: 1588859
Description: Predicted to have GTPase activator activity. Predicted to be involved in cytoskeleton organization and negative regulation of apoptotic process. Predicted to localize to cytosol. Orthologous to human ARHGAP10 (Rho GTPase activating protein 10); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC688429; rho GTPase-activating protein 10; similar to Rho GTPase activating protein 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21930,448,572 - 30,710,315 (+)NCBI
Rnor_6.0 Ensembl1934,139,997 - 34,402,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01934,138,978 - 34,406,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01945,021,122 - 45,282,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,261,771 - 32,521,913 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1929,930,167 - 30,186,673 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:11238453   PMID:15471851  


Genomics

Comparative Map Data
Arhgap10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21930,448,572 - 30,710,315 (+)NCBI
Rnor_6.0 Ensembl1934,139,997 - 34,402,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01934,138,978 - 34,406,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01945,021,122 - 45,282,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,261,771 - 32,521,913 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1929,930,167 - 30,186,673 (+)NCBICelera
Cytogenetic Map19q11NCBI
ARHGAP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4147,732,063 - 148,072,776 (+)EnsemblGRCh38hg38GRCh38
GRCh384147,732,063 - 148,072,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374148,653,239 - 148,993,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364148,872,903 - 149,213,377 (+)NCBINCBI36hg18NCBI36
Build 344149,011,057 - 149,351,531NCBI
Celera4145,974,548 - 146,315,244 (+)NCBI
Cytogenetic Map4q31.23NCBI
HuRef4144,380,575 - 144,721,071 (+)NCBIHuRef
CHM1_14148,632,138 - 148,972,573 (+)NCBICHM1_1
Arhgap10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39877,976,995 - 78,244,628 (-)NCBIGRCm39mm39
GRCm39 Ensembl877,976,995 - 78,244,582 (-)Ensembl
GRCm38877,250,366 - 77,517,999 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl877,250,366 - 77,517,953 (-)EnsemblGRCm38mm10GRCm38
MGSCv37879,774,265 - 80,041,806 (-)NCBIGRCm37mm9NCBIm37
MGSCv36880,146,991 - 80,413,857 (-)NCBImm8
Celera881,539,175 - 81,809,141 (-)NCBICelera
Cytogenetic Map8C1NCBI
Arhgap10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554712,804,162 - 3,052,565 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554712,757,063 - 3,052,565 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14151,726,549 - 152,066,977 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4151,726,549 - 152,066,977 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04140,054,130 - 140,412,646 (+)NCBIMhudiblu_PPA_v0panPan3
ARHGAP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11546,064,489 - 46,382,079 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1546,070,312 - 46,381,839 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1546,457,487 - 46,775,260 (+)NCBI
ROS_Cfam_1.01546,738,153 - 47,057,893 (+)NCBI
UMICH_Zoey_3.11546,006,428 - 46,324,428 (+)NCBI
UNSW_CanFamBas_1.01546,103,535 - 46,422,910 (+)NCBI
UU_Cfam_GSD_1.01546,412,616 - 46,730,944 (+)NCBI
Arhgap10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530144,036,353 - 44,330,083 (-)NCBI
SpeTri2.0NW_0049365351,473,693 - 1,767,437 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl880,675,001 - 81,024,492 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1880,674,999 - 81,024,501 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2885,799,351 - 86,042,332 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1794,233,257 - 94,568,042 (+)NCBI
ChlSab1.1 Ensembl794,216,032 - 94,568,502 (+)Ensembl
Vero_WHO_p1.0NW_02366603773,923,677 - 74,275,881 (+)NCBI
Arhgap10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248536,360,119 - 6,424,247 (-)NCBI

Position Markers
D19Got15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,462,251 - 30,462,407 (+)MAPPER
Rnor_6.01934,153,725 - 34,153,880NCBIRnor6.0
Rnor_5.01945,034,585 - 45,034,740UniSTSRnor5.0
RGSC_v3.41932,275,443 - 32,275,598RGDRGSC3.4
RGSC_v3.41932,275,443 - 32,275,598UniSTSRGSC3.4
RGSC_v3.11932,280,324 - 32,280,479RGD
Celera1929,943,781 - 29,943,936UniSTS
RH 3.4 Map19229.3RGD
RH 3.4 Map19229.3UniSTS
RH 2.0 Map19339.2RGD
Cytogenetic Map19q11UniSTS
D19Got108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,682,460 - 30,682,659 (+)MAPPER
Rnor_6.01934,373,703 - 34,373,901NCBIRnor6.0
Rnor_5.01945,254,457 - 45,254,655UniSTSRnor5.0
RGSC_v3.41932,494,196 - 32,494,394UniSTSRGSC3.4
Celera1930,159,693 - 30,159,899UniSTS
Cytogenetic Map19q11UniSTS
RH128161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,710,078 - 30,710,264 (+)MAPPER
Rnor_6.01934,402,706 - 34,402,891NCBIRnor6.0
Rnor_5.01945,281,873 - 45,282,058UniSTSRnor5.0
RGSC_v3.41932,522,183 - 32,522,368UniSTSRGSC3.4
Celera1930,186,943 - 30,187,128UniSTS
RH 3.4 Map19235.6UniSTS
Cytogenetic Map19q11UniSTS
BI296164  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,489,233 - 30,489,384 (+)MAPPER
Rnor_6.01934,180,996 - 34,181,146NCBIRnor6.0
Rnor_5.01945,061,413 - 45,061,563UniSTSRnor5.0
RGSC_v3.41932,301,735 - 32,301,885UniSTSRGSC3.4
Celera1929,971,072 - 29,971,222UniSTS
RH 3.4 Map19225.2UniSTS
Cytogenetic Map19q11UniSTS
RH139267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,511,961 - 30,512,089 (+)MAPPER
Rnor_6.01934,204,203 - 34,204,330NCBIRnor6.0
Rnor_5.01945,084,621 - 45,084,748UniSTSRnor5.0
RGSC_v3.41932,324,466 - 32,324,593UniSTSRGSC3.4
Celera1929,992,287 - 29,992,414UniSTS
RH 3.4 Map19234.8UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic MapXq12UniSTS
AA800507  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,446,792 - 30,446,962 (+)MAPPER
Rnor_6.01934,138,170 - 34,138,339NCBIRnor6.0
Rnor_5.01945,019,444 - 45,019,613UniSTSRnor5.0
RGSC_v3.41932,259,718 - 32,259,887UniSTSRGSC3.4
Celera1929,928,156 - 29,928,325UniSTS
RH 3.4 Map19251.1UniSTS
Cytogenetic Map19q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19138221845Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19138221845Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19138221845Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19138221845Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19104464846044648Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19195770746957707Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19243296347217667Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)19370183548701835Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)19370183548701835Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19500757143907843Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19650676160220581Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19807254547318201Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191130392747879277Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191593952838798459Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191702800352538299Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192445572643907843Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192445762737140233Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192481825762275575Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)193119430141686140Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)193119430141686140Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)193119430141686140Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)193299439262275575Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:76
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000017867
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 22 6 10 6 8 11 26 35 41 10 8
Low 3 35 35 9 35 48 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017867   ⟹   ENSRNOP00000017867
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1934,139,997 - 34,402,436 (+)Ensembl
RefSeq Acc Id: NM_001109501   ⟹   NP_001102971
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,634 - 30,709,809 (+)NCBI
Rnor_6.01934,139,997 - 34,402,436 (+)NCBI
Rnor_5.01945,021,122 - 45,282,107 (+)NCBI
RGSC_v3.41932,261,771 - 32,521,913 (+)RGD
Celera1929,930,167 - 30,186,673 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772530   ⟹   XP_008770752
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01934,139,957 - 34,406,593 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772531   ⟹   XP_008770753
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,824 - 30,709,742 (+)NCBI
Rnor_6.01934,139,957 - 34,402,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772532   ⟹   XP_008770754
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01934,219,572 - 34,402,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601356   ⟹   XP_017456845
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01934,138,978 - 34,402,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601357   ⟹   XP_017456846
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01934,204,786 - 34,402,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601358   ⟹   XP_017456847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,574 - 30,653,346 (+)NCBI
Rnor_6.01934,139,957 - 34,344,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601359   ⟹   XP_017456848
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,574 - 30,654,933 (+)NCBI
Rnor_6.01934,139,957 - 34,346,157 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097986   ⟹   XP_038953914
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,578 - 30,710,315 (+)NCBI
RefSeq Acc Id: XM_039097987   ⟹   XP_038953915
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,578 - 30,710,315 (+)NCBI
RefSeq Acc Id: XM_039097988   ⟹   XP_038953916
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,459,875 - 30,710,315 (+)NCBI
RefSeq Acc Id: XM_039097989   ⟹   XP_038953917
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,512,497 - 30,710,313 (+)NCBI
RefSeq Acc Id: XM_039097990   ⟹   XP_038953918
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,512,629 - 30,710,315 (+)NCBI
RefSeq Acc Id: XM_039097991   ⟹   XP_038953919
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,512,793 - 30,710,315 (+)NCBI
RefSeq Acc Id: XM_039097992   ⟹   XP_038953920
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,512,433 - 30,710,313 (+)NCBI
RefSeq Acc Id: XM_039097993   ⟹   XP_038953921
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,572 - 30,581,209 (+)NCBI
RefSeq Acc Id: XM_039097994   ⟹   XP_038953922
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,574 - 30,601,299 (+)NCBI
RefSeq Acc Id: XM_039097995   ⟹   XP_038953923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,573 - 30,607,633 (+)NCBI
RefSeq Acc Id: XR_005496687
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,575 - 30,614,872 (+)NCBI
RefSeq Acc Id: XR_005496688
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21930,448,573 - 30,614,872 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102971   ⟸   NM_001109501
- UniProtKB: D4AB50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770753   ⟸   XM_008772531
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008770752   ⟸   XM_008772530
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008770754   ⟸   XM_008772532
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017456845   ⟸   XM_017601356
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456848   ⟸   XM_017601359
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017456847   ⟸   XM_017601358
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017456846   ⟸   XM_017601357
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000017867   ⟸   ENSRNOT00000017867
RefSeq Acc Id: XP_038953921   ⟸   XM_039097993
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038953923   ⟸   XM_039097995
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038953922   ⟸   XM_039097994
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038953914   ⟸   XM_039097986
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953915   ⟸   XM_039097987
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953916   ⟸   XM_039097988
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953920   ⟸   XM_039097992
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953917   ⟸   XM_039097989
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953918   ⟸   XM_039097990
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953919   ⟸   XM_039097991
- Peptide Label: isoform X4
Protein Domains
PH   Rho-GAP   SH3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701059
Promoter ID:EPDNEW_R11582
Type:initiation region
Name:Arhgap10_1
Description:Rho GTPase activating protein 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01934,140,012 - 34,140,072EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588859 AgrOrtholog
Ensembl Genes ENSRNOG00000013152 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017867 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017867 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro AH/BAR-dom UniProtKB/TrEMBL
  GRAF2 UniProtKB/TrEMBL
  GRAF2_SH3 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report rno:688429 UniProtKB/TrEMBL
NCBI Gene 688429 ENTREZGENE
PANTHER PTHR12552:SF5 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PhenoGen Arhgap10 PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP Rho_GAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SSF103657 UniProtKB/TrEMBL
UniProt D4AB50 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Arhgap10  Rho GTPase activating protein 10  LOC688429  similar to Rho GTPase activating protein 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC688429  similar to Rho GTPase activating protein 10  LOC684731  similar to Rho GTPase activating protein 10  Data Merged 1643240 APPROVED
2006-11-19 LOC688429  similar to Rho GTPase activating protein 10      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684731  similar to Rho GTPase activating protein 10      Symbol and Name status set to provisional 70820 PROVISIONAL