Ptger1 (prostaglandin E receptor 1) - Rat Genome Database

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Gene: Ptger1 (prostaglandin E receptor 1) Rattus norvegicus
Analyze
Symbol: Ptger1
Name: prostaglandin E receptor 1
RGD ID: 3434
Description: Enables prostaglandin E receptor activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway; inflammatory response; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within response to lipopolysaccharide. Predicted to be active in plasma membrane. Used to study gastric ulcer. Orthologous to human PTGER1 (prostaglandin E receptor 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EP1; EP1 prostanoid receptor; PGE receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1); prostaglandin E receptor EP1 subtype; prostaglandin E2 receptor EP1 subtype; prostanoid EP1 receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,374,983 - 41,379,593 (-)NCBIGRCr8
mRatBN7.21924,470,258 - 24,473,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,467,532 - 24,473,559 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1931,291,382 - 31,294,683 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,945,803 - 31,949,104 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01934,168,630 - 34,171,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01924,799,422 - 24,803,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,800,072 - 24,803,373 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,779,098 - 35,782,528 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,160,729 - 26,163,156 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11926,165,447 - 26,167,982 (-)NCBI
Celera1924,013,194 - 24,016,495 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aldehydo-D-glucose  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
CGP 52608  (ISO)
cyclophosphamide  (EXP)
D-glucose  (EXP)
D-mannitol  (EXP)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (EXP)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (EXP)
graphite  (EXP)
Licochalcone B  (ISO)
mifepristone  (EXP)
misoprostol  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
naphthalene  (ISO)
okadaic acid  (ISO)
Osajin  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PhIP  (EXP)
phosgene  (ISO)
Pomiferin  (ISO)
pristane  (ISO)
progesterone  (EXP)
prostaglandin E2  (EXP,ISO)
puerarin  (ISO)
resveratrol  (ISO)
Rosavin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP)
trovafloxacin  (ISO)
tungsten  (ISO)
urethane  (ISO)
vinyl carbamate  (ISO)
wortmannin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach. Araki H, etal., Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:116-24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Suppression of prostaglandin E receptor signaling by the variant form of EP1 subtype. Okuda-Ashitaka E, etal., J Biol Chem 1996 Dec 6;271(49):31255-61.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9537820   PMID:14552899   PMID:14670979   PMID:15126118   PMID:15833739   PMID:15834430   PMID:16280600   PMID:16393343   PMID:16646980   PMID:16707842   PMID:17110143   PMID:17567965  
PMID:17710229   PMID:18093985   PMID:19732740   PMID:20798358   PMID:21270690   PMID:21939736   PMID:22023852   PMID:22061836   PMID:22984630   PMID:23220160   PMID:23824501   PMID:23842570  
PMID:24614038   PMID:24952362   PMID:26648273   PMID:32165825   PMID:35537317  


Genomics

Comparative Map Data
Ptger1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,374,983 - 41,379,593 (-)NCBIGRCr8
mRatBN7.21924,470,258 - 24,473,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,467,532 - 24,473,559 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1931,291,382 - 31,294,683 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,945,803 - 31,949,104 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01934,168,630 - 34,171,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01924,799,422 - 24,803,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,800,072 - 24,803,373 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,779,098 - 35,782,528 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,160,729 - 26,163,156 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11926,165,447 - 26,167,982 (-)NCBI
Celera1924,013,194 - 24,016,495 (-)NCBICelera
Cytogenetic Map19q11NCBI
PTGER1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,472,466 - 14,475,354 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,472,466 - 14,475,354 (-)EnsemblGRCh38hg38GRCh38
GRCh371914,583,278 - 14,586,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,444,278 - 14,447,174 (-)NCBINCBI36Build 36hg18NCBI36
Build 341914,444,278 - 14,447,174NCBI
Celera1914,477,399 - 14,480,295 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,153,393 - 14,156,289 (-)NCBIHuRef
CHM1_11914,583,257 - 14,586,164 (-)NCBICHM1_1
T2T-CHM13v2.01914,599,099 - 14,601,987 (-)NCBIT2T-CHM13v2.0
Ptger1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,393,171 - 84,399,385 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,393,307 - 84,399,382 (+)EnsemblGRCm39 Ensembl
GRCm38883,666,644 - 83,672,756 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,666,678 - 83,672,753 (+)EnsemblGRCm38mm10GRCm38
MGSCv37886,190,539 - 86,194,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36886,556,745 - 86,560,208 (+)NCBIMGSCv36mm8
Celera887,957,431 - 87,960,894 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.22NCBI
Ptger1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541533,063,052 - 33,067,580 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541533,063,052 - 33,067,580 (-)NCBIChiLan1.0ChiLan1.0
PTGER1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,402,243 - 19,406,282 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,404,124 - 18,407,438 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,035,876 - 14,038,812 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11914,879,798 - 14,881,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PTGER1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,156,055 - 48,159,838 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,157,973 - 48,159,921 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2048,030,811 - 48,039,003 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02048,673,636 - 48,681,830 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,661,602 - 48,678,490 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12047,888,190 - 47,893,357 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,311,534 - 48,319,721 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,554,374 - 48,562,556 (+)NCBIUU_Cfam_GSD_1.0
Ptger1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,335,030 - 207,342,686 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366593,012,012 - 3,018,275 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366593,014,633 - 3,018,617 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl264,797,216 - 64,800,458 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1264,796,944 - 64,800,199 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,154,866 - 65,156,438 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTGER1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,131,328 - 13,134,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,131,424 - 13,133,190 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,519,439 - 6,524,611 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ptger1
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:36
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000005470
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat

Markers in Region
Ptger1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,470,769 - 24,470,917 (-)MAPPERmRatBN7.2
Rnor_6.01924,802,714 - 24,802,861NCBIRnor6.0
Rnor_5.01935,781,869 - 35,782,016UniSTSRnor5.0
RGSC_v3.41926,161,028 - 26,161,175UniSTSRGSC3.4
Celera1924,013,706 - 24,013,853UniSTS
Cytogenetic Map19q11UniSTS
RH132067  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,472,562 - 24,472,761 (-)MAPPERmRatBN7.2
Rnor_6.01924,800,870 - 24,801,068NCBIRnor6.0
Rnor_5.01935,780,025 - 35,780,223UniSTSRnor5.0
RGSC_v3.41926,162,821 - 26,163,019UniSTSRGSC3.4
Celera1924,015,499 - 24,015,697UniSTS
Cytogenetic Map19q11UniSTS
RH143527  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,470,931 - 24,471,174 (-)MAPPERmRatBN7.2
Rnor_6.01924,802,457 - 24,802,699NCBIRnor6.0
Rnor_5.01935,781,612 - 35,781,854UniSTSRnor5.0
RGSC_v3.41926,161,190 - 26,161,432UniSTSRGSC3.4
Celera1924,013,868 - 24,014,110UniSTS
Cytogenetic Map19q11UniSTS
RH94446  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,470,261 - 24,470,430 (-)MAPPERmRatBN7.2
Rnor_6.01924,803,201 - 24,803,369NCBIRnor6.0
Rnor_5.01935,782,356 - 35,782,524UniSTSRnor5.0
Celera1924,013,198 - 24,013,366UniSTS
Cytogenetic Map19q11UniSTS
RH140664  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,470,489 - 24,470,678 (-)MAPPERmRatBN7.2
Rnor_6.01924,802,953 - 24,803,141NCBIRnor6.0
Rnor_5.01935,782,108 - 35,782,296UniSTSRnor5.0
RGSC_v3.41926,160,748 - 26,160,936UniSTSRGSC3.4
Celera1924,013,426 - 24,013,614UniSTS
Cytogenetic Map19q11UniSTS
PMC199184P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,471,578 - 24,472,296 (-)MAPPERmRatBN7.2
Rnor_6.01924,801,335 - 24,802,052NCBIRnor6.0
Rnor_5.01935,780,490 - 35,781,207UniSTSRnor5.0
RGSC_v3.41926,161,837 - 26,162,554UniSTSRGSC3.4
Celera1924,014,515 - 24,015,232UniSTS
Cytogenetic Map19q11UniSTS
PMC209534P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,471,632 - 24,472,298 (-)MAPPERmRatBN7.2
Rnor_6.01924,801,333 - 24,801,998NCBIRnor6.0
Rnor_5.01935,780,488 - 35,781,153UniSTSRnor5.0
RGSC_v3.41926,161,891 - 26,162,556UniSTSRGSC3.4
Celera1924,014,569 - 24,015,234UniSTS
Cytogenetic Map19q11UniSTS
PMC327192P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,471,416 - 24,472,245 (-)MAPPERmRatBN7.2
Rnor_6.01924,801,386 - 24,802,214NCBIRnor6.0
Rnor_5.01935,780,541 - 35,781,369UniSTSRnor5.0
RGSC_v3.41926,161,675 - 26,162,503UniSTSRGSC3.4
Celera1924,014,353 - 24,015,181UniSTS
Cytogenetic Map19q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 13 19 19 5 11
Low 11 14 11 11 8 11 19 16 26 8
Below cutoff 32 14 14 14 55 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005470   ⟹   ENSRNOP00000005470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,470,258 - 24,473,559 (-)Ensembl
Rnor_6.0 Ensembl1924,800,072 - 24,803,373 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113609   ⟹   ENSRNOP00000084861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,467,532 - 24,472,898 (-)Ensembl
RefSeq Acc Id: NM_001278475   ⟹   NP_001265404
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,374,983 - 41,378,284 (-)NCBI
mRatBN7.21924,470,258 - 24,473,559 (-)NCBI
Rnor_6.01924,800,072 - 24,803,373 (+)NCBI
Rnor_5.01935,779,098 - 35,782,528 (+)NCBI
Celera1924,013,194 - 24,016,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097501   ⟹   XP_038953429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,375,397 - 41,379,593 (-)NCBI
mRatBN7.21924,470,258 - 24,473,687 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001265404   ⟸   NM_001278475
- UniProtKB: P97537 (UniProtKB/Swiss-Prot),   P70597 (UniProtKB/Swiss-Prot),   A6IYD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005470   ⟸   ENSRNOT00000005470
RefSeq Acc Id: XP_038953429   ⟸   XM_039097501
- Peptide Label: isoform X1
- UniProtKB: A6IYD4 (UniProtKB/TrEMBL),   A0A8I6A021 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000084861   ⟸   ENSRNOT00000113609
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70597-F1-model_v2 AlphaFold P70597 1-405 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3434 AgrOrtholog
BioCyc Gene G2FUF-6021 BioCyc
Ensembl Genes ENSRNOG00000004094 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005470 ENTREZGENE
  ENSRNOT00000005470.5 UniProtKB/Swiss-Prot
  ENSRNOT00000113609.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_DP_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_EP1_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25637 UniProtKB/Swiss-Prot
NCBI Gene 25637 ENTREZGENE
PANTHER PTHR11866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11866:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptger1 PhenoGen
PRINTS PROSTAGLNDNR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTANOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDEP1R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004094 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217548
  TC217549
UniProt A0A8I6A021 ENTREZGENE, UniProtKB/TrEMBL
  A6IYD3 ENTREZGENE, UniProtKB/TrEMBL
  A6IYD4 ENTREZGENE, UniProtKB/TrEMBL
  P70597 ENTREZGENE
  P97537 ENTREZGENE
  PE2R1_RAT UniProtKB/Swiss-Prot
UniProt Secondary P97537 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Ptger1  prostaglandin E receptor 1  Ptger1  prostaglandin E receptor 1 (subtype EP1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Ptger1  prostaglandin E receptor 1 (subtype EP1)  Ptger1  prostaglandin E receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Ptger1  prostaglandin E receptor 1  Ptger1  Prostaglandin E receptor 1 (subtype EP1)  Name updated 629478 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function alternative splice variant may decrease prostaglandin E receptor mediated signaling 729742
gene_transcript variant form contains a 49 amino acid change, lacks an intracellular C-terminal tai, and is likely due to alternative splicing 729742