Tecr (trans-2,3-enoyl-CoA reductase) - Rat Genome Database

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Gene: Tecr (trans-2,3-enoyl-CoA reductase) Rattus norvegicus
Analyze
Symbol: Tecr
Name: trans-2,3-enoyl-CoA reductase
RGD ID: 620376
Description: Predicted to enable very-long-chain enoyl-CoA reductase activity. Predicted to be involved in fatty acid elongation; sphingolipid metabolic process; and very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 14. Orthologous to human TECR (trans-2,3-enoyl-CoA reductase); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glycoprotein, synaptic 2; Gpsn2; neuroprotective protein 13; SC2; synaptic glycoprotein SC2; TER; very-long-chain enoyl-CoA reductase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21924,526,705 - 24,568,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,541,615 - 24,568,168 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1931,348,025 - 31,389,488 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01932,002,436 - 32,043,900 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01934,225,211 - 34,266,534 (+)NCBIRnor_WKY
Rnor_6.01924,705,478 - 24,732,024 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,705,481 - 24,732,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,684,508 - 35,711,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,232,602 - 26,259,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11926,237,427 - 26,264,112 (+)NCBI
Celera1924,083,400 - 24,108,790 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
GW 4064  (ISO)
hydrogen cyanide  (ISO)
imidacloprid  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
maneb  (ISO)
methidathion  (ISO)
nimesulide  (EXP)
obeticholic acid  (ISO)
oleic acid  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
potassium cyanide  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Molecular cloning of a novel mRNA using an antibody directed against synaptic glycoproteins. Johnston IG, etal., J Neurosci Res 1992 Jun;32(2):159-66.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12482854   PMID:15489334   PMID:21124846   PMID:21630459   PMID:22871113   PMID:24220030   PMID:25049234   PMID:33450132  


Genomics

Comparative Map Data
Tecr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21924,526,705 - 24,568,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,541,615 - 24,568,168 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1931,348,025 - 31,389,488 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01932,002,436 - 32,043,900 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01934,225,211 - 34,266,534 (+)NCBIRnor_WKY
Rnor_6.01924,705,478 - 24,732,024 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,705,481 - 24,732,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,684,508 - 35,711,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,232,602 - 26,259,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11926,237,427 - 26,264,112 (+)NCBI
Celera1924,083,400 - 24,108,790 (+)NCBICelera
Cytogenetic Map19q11NCBI
TECR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,527,726 - 14,565,980 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1914,517,085 - 14,565,980 (+)EnsemblGRCh38hg38GRCh38
GRCh371914,640,372 - 14,676,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,501,382 - 14,537,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 341914,501,381 - 14,537,791NCBI
Celera485,160,139 - 85,188,395 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,210,172 - 14,246,278 (+)NCBIHuRef
CHM1_11914,640,339 - 14,677,621 (+)NCBICHM1_1
T2T-CHM13v2.01914,656,288 - 14,692,721 (+)NCBIT2T-CHM13v2.0
Tecr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,298,327 - 84,321,120 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,298,327 - 84,334,600 (-)EnsemblGRCm39 Ensembl
GRCm38883,571,698 - 83,594,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,571,698 - 83,607,971 (-)EnsemblGRCm38mm10GRCm38
MGSCv37886,095,597 - 86,118,390 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36886,461,805 - 86,484,570 (-)NCBIMGSCv36mm8
Celera887,857,633 - 87,880,363 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.22NCBI
Tecr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541533,135,646 - 33,143,145 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541533,112,098 - 33,138,810 (+)NCBIChiLan1.0ChiLan1.0
TECR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11914,936,911 - 14,972,784 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,936,911 - 14,972,784 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01914,092,967 - 14,129,025 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TECR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,094,891 - 48,120,384 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,094,961 - 48,120,291 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2047,971,579 - 47,996,850 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02048,612,057 - 48,637,301 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,612,060 - 48,637,270 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12047,826,045 - 47,851,234 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,252,269 - 48,277,610 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,495,253 - 48,520,440 (-)NCBIUU_Cfam_GSD_1.0
Tecr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,273,757 - 207,303,057 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366593,051,566 - 3,084,788 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366593,051,657 - 3,080,948 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TECR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1264,723,698 - 64,752,209 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,189,388 - 65,191,199 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TECR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,186,972 - 13,224,908 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,188,450 - 13,227,776 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,430,084 - 6,467,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tecr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249011,643,520 - 1,668,550 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249011,643,465 - 1,668,544 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tecr
271 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:44
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000037608
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat

Markers in Region
RH139870  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,566,788 - 24,567,167 (-)MAPPERmRatBN7.2
mRatBN7.2147,264,139 - 47,264,343 (+)MAPPERmRatBN7.2
Rnor_6.0147,587,515 - 47,587,718NCBIRnor6.0
Rnor_6.01924,706,479 - 24,706,854NCBIRnor6.0
Rnor_5.01935,685,509 - 35,686,173UniSTSRnor5.0
Rnor_5.0148,887,902 - 48,888,105UniSTSRnor5.0
RGSC_v3.4141,483,433 - 41,483,636UniSTSRGSC3.4
RGSC_v3.41926,257,866 - 26,258,288UniSTSRGSC3.4
Celera142,948,096 - 42,948,299UniSTS
RH 3.4 Map1541.7UniSTS
Cytogenetic Map1q11UniSTS
Cytogenetic Map19q11UniSTS
BI282960  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,567,146 - 24,567,622 (-)MAPPERmRatBN7.2
mRatBN7.2147,263,950 - 47,264,160 (+)MAPPERmRatBN7.2
Rnor_6.0147,587,326 - 47,587,535NCBIRnor6.0
Rnor_6.01924,706,024 - 24,706,499NCBIRnor6.0
Rnor_5.01935,685,054 - 35,685,529UniSTSRnor5.0
Rnor_5.0148,887,713 - 48,887,922UniSTSRnor5.0
RGSC_v3.41926,258,268 - 26,258,743UniSTSRGSC3.4
RGSC_v3.4141,483,244 - 41,483,453UniSTSRGSC3.4
Celera142,947,907 - 42,948,116UniSTS
Celera1924,107,769 - 24,108,244UniSTS
RH 3.4 Map1540.4UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map1q11UniSTS
AI173355  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,567,431 - 24,567,631 (-)MAPPERmRatBN7.2
Rnor_6.01924,706,015 - 24,706,214NCBIRnor6.0
Rnor_5.01935,685,045 - 35,685,244UniSTSRnor5.0
RGSC_v3.41926,258,553 - 26,258,752UniSTSRGSC3.4
Celera1924,108,054 - 24,108,253UniSTS
Cytogenetic Map19q11UniSTS
Gpsn2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2147,263,787 - 47,263,993 (+)MAPPERmRatBN7.2
mRatBN7.21924,567,579 - 24,568,023 (-)MAPPERmRatBN7.2
Rnor_6.01924,705,623 - 24,706,066NCBIRnor6.0
Rnor_6.0147,587,163 - 47,587,368NCBIRnor6.0
Rnor_5.01935,684,653 - 35,685,096UniSTSRnor5.0
Rnor_5.0148,887,550 - 48,887,755UniSTSRnor5.0
RGSC_v3.41926,258,701 - 26,259,144UniSTSRGSC3.4
RGSC_v3.4141,483,081 - 41,483,286UniSTSRGSC3.4
Celera142,947,744 - 42,947,949UniSTS
Celera1924,108,202 - 24,108,645UniSTS
Cytogenetic Map1q11UniSTS
Cytogenetic Map19q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001398679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU000473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S45663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000037608   ⟹   ENSRNOP00000035416
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,615 - 24,568,165 (+)Ensembl
Rnor_6.0 Ensembl1924,705,481 - 24,732,024 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096596   ⟹   ENSRNOP00000080279
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,564,386 - 24,568,168 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098878   ⟹   ENSRNOP00000093730
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,565,140 - 24,568,165 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102273   ⟹   ENSRNOP00000095860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,615 - 24,568,160 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103758   ⟹   ENSRNOP00000097089
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,651 - 24,568,124 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104728   ⟹   ENSRNOP00000097514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,685 - 24,568,142 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115783   ⟹   ENSRNOP00000083676
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,685 - 24,568,163 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115881   ⟹   ENSRNOP00000089376
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,541,642 - 24,568,168 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000120184   ⟹   ENSRNOP00000094888
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,565,135 - 24,568,165 (+)Ensembl
RefSeq Acc Id: NM_138549   ⟹   NP_612558
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,541,615 - 24,568,168 (+)NCBI
Rnor_6.01924,705,478 - 24,732,024 (-)NCBI
Rnor_5.01935,684,508 - 35,711,344 (-)NCBI
RGSC_v3.41926,232,602 - 26,259,289 (+)RGD
Celera1924,083,400 - 24,108,790 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255218   ⟹   XP_006255280
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,541,616 - 24,568,168 (+)NCBI
Rnor_6.01924,705,478 - 24,732,023 (-)NCBI
Rnor_5.01935,684,508 - 35,711,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097453   ⟹   XP_038953381
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,565,085 - 24,568,168 (+)NCBI
RefSeq Acc Id: XM_039097454   ⟹   XP_038953382
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,565,085 - 24,568,168 (+)NCBI
RefSeq Acc Id: XM_039097455   ⟹   XP_038953383
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,526,705 - 24,568,168 (+)NCBI
RefSeq Acc Id: XM_039097456   ⟹   XP_038953384
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21924,526,846 - 24,568,168 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_612558   ⟸   NM_138549
- UniProtKB: Q64232 (UniProtKB/Swiss-Prot),   B3SVE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255280   ⟸   XM_006255218
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000035416   ⟸   ENSRNOT00000037608
RefSeq Acc Id: XP_038953383   ⟸   XM_039097455
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953384   ⟸   XM_039097456
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953381   ⟸   XM_039097453
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953382   ⟸   XM_039097454
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000083676   ⟸   ENSRNOT00000115783
RefSeq Acc Id: ENSRNOP00000093730   ⟸   ENSRNOT00000098878
RefSeq Acc Id: ENSRNOP00000095860   ⟸   ENSRNOT00000102273
RefSeq Acc Id: ENSRNOP00000097514   ⟸   ENSRNOT00000104728
RefSeq Acc Id: ENSRNOP00000097089   ⟸   ENSRNOT00000103758
RefSeq Acc Id: ENSRNOP00000080279   ⟸   ENSRNOT00000096596
RefSeq Acc Id: ENSRNOP00000094888   ⟸   ENSRNOT00000120184
RefSeq Acc Id: ENSRNOP00000089376   ⟸   ENSRNOT00000115881
Protein Domains
S5A_REDUCTASE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64232-F1-model_v2 AlphaFold Q64232 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701001
Promoter ID:EPDNEW_R11524
Type:initiation region
Name:Tecr_1
Description:trans-2,3-enoyl-CoA reductase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01924,731,981 - 24,732,041EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620376 AgrOrtholog
BioCyc Gene G2FUF-6016 BioCyc
BioCyc Pathway PWY-5080 [very long chain fatty acid biosynthesis I] BioCyc
  PWY-6598 [sciadonate biosynthesis] BioCyc
  PWY-7036 [very long chain fatty acid biosynthesis II] BioCyc
  PWY-7049 [icosapentaenoate biosynthesis II (6-desaturase, mammals)] BioCyc
  PWY-7592 [arachidonate biosynthesis III (6-desaturase, mammals)] BioCyc
  PWY-7606 [docosahexaenoate biosynthesis III (6-desaturase, mammals)] BioCyc
  PWY-7619 [juniperonate biosynthesis] BioCyc
  PWY-7726 [(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)] BioCyc
  PWY-8041 [ultra-long-chain fatty acid biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000021808 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000035416 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000080279.1 UniProtKB/TrEMBL
  ENSRNOP00000083676.1 UniProtKB/TrEMBL
  ENSRNOP00000089376 ENTREZGENE
  ENSRNOP00000089376.1 UniProtKB/TrEMBL
  ENSRNOP00000093730 ENTREZGENE
  ENSRNOP00000093730.1 UniProtKB/TrEMBL
  ENSRNOP00000094888 ENTREZGENE
  ENSRNOP00000094888.1 UniProtKB/TrEMBL
  ENSRNOP00000095860.1 UniProtKB/TrEMBL
  ENSRNOP00000097089.1 UniProtKB/TrEMBL
  ENSRNOP00000097514.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037608 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000096596.1 UniProtKB/TrEMBL
  ENSRNOT00000098878 ENTREZGENE
  ENSRNOT00000098878.1 UniProtKB/TrEMBL
  ENSRNOT00000102273.1 UniProtKB/TrEMBL
  ENSRNOT00000103758.1 UniProtKB/TrEMBL
  ENSRNOT00000104728.1 UniProtKB/TrEMBL
  ENSRNOT00000115783.1 UniProtKB/TrEMBL
  ENSRNOT00000115881 ENTREZGENE
  ENSRNOT00000115881.1 UniProtKB/TrEMBL
  ENSRNOT00000120184 ENTREZGENE
  ENSRNOT00000120184.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920522 IMAGE-MGC_LOAD
InterPro 3-oxo-5_a-steroid_4-DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRD5A/TECR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:191576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72691 IMAGE-MGC_LOAD
NCBI Gene 191576 ENTREZGENE
PANTHER PTHR10556 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Steroid_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tecr PhenoGen
PROSITE S5A_REDUCTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZWG2_RAT UniProtKB/TrEMBL
  A0A8I6AI38 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKU7_RAT UniProtKB/TrEMBL
  A0A8I6ALN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMG3_RAT UniProtKB/TrEMBL
  A0A8I6AVZ3_RAT UniProtKB/TrEMBL
  A0A8I6AWG2_RAT UniProtKB/TrEMBL
  A0A8I6G6D7_RAT UniProtKB/TrEMBL
  B3SVE9 ENTREZGENE, UniProtKB/TrEMBL
  Q64232 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-10-22 Tecr  trans-2,3-enoyl-CoA reductase  Gpsn2  glycoprotein, synaptic 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gpsn2  glycoprotein, synaptic 2  SC2  synaptic glycoprotein SC2  Symbol and Name updated 1299863 APPROVED
2002-08-07 SC2  synaptic glycoprotein SC2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology shows some similarity to 5 alpha-reductase, a microsomal membrane protein important in testosterone metabolism 634003