Cdh3 (cadherin 3) - Rat Genome Database

Name: Cdh3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cdh3 (cadherin 3) Rattus norvegicus

Analyze

Symbol:

Cdh3

Name:

cadherin 3

RGD ID:

621089

Description:

Involved in response to xenobiotic stimulus. Predicted to be located in adherens junction and plasma membrane. Human ortholog(s) of this gene implicated in congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome. Orthologous to human CDH3 (cadherin 3); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2-acetamidofluorene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cadherin 3, type 1, P-cadherin (placental); cadherin-3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDH3 (cadherin 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cdh3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdh3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDH3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDH3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdh3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDH3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDH3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdh3 (cadherin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC4A7 (solute carrier family 4 member 7)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CDH3 (cadherin 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cdh3 (cadherin 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdh31 (cadherin 31)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	cdh1 (cadherin 1, type 1, E-cadherin (epithelial))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	cdh28	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	cdh3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	34,393,596 - 34,444,084 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	34,393,727 - 34,444,084 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	41,209,266 - 41,259,606 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	41,862,587 - 41,912,930 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	44,161,722 - 44,212,069 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	38,668,957 - 38,719,801 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	38,669,230 - 38,719,677 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	49,536,859 - 49,587,578 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	36,343,823 - 36,393,819 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	36,395,654 - 36,397,989 (+)	NCBI
Celera	19	33,820,490 - 33,870,862 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

congenital hypotrichosis with juvenile macular dystrophy (ISO)

ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

hereditary diffuse gastric cancer (ISO)

hypotrichosis 1 (ISO)

macular degeneration (ISO)

Multiple Abnormalities (ISO)

ovarian cyst (ISO)

prostate cancer (ISO)

retinitis pigmentosa (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

1-nitropyrene (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-acetamidofluorene (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP,ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amosite asbestos (ISO)

apocynin (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chloropicrin (ISO)

chrysene (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclophosphamide (EXP)

cytarabine (ISO)

deguelin (ISO)

Deoxycorticosterone acetate (ISO)

dibutyl phthalate (ISO)

diiodine (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

glycidol (EXP)

hexadecanoic acid (ISO)

homocysteine (ISO)

hydrogen peroxide (ISO)

ibuprofen (ISO)

inulin (ISO)

isobutanol (ISO)

lead diacetate (EXP)

lead(0) (ISO)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

orphenadrine (EXP)

p-menthan-3-ol (ISO)

panobinostat (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

puromycin (ISO)

rofecoxib (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sotorasib (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

trametinib (ISO)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adherens junction organization (IBA)

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (IBA)

cell morphogenesis (IBA)

cell-cell adhesion (ISO)

cell-cell adhesion mediated by cadherin (IBA)

cell-cell junction assembly (IBA)

hair cycle process (ISO)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

keratinization (ISO)

negative regulation of timing of catagen (ISO)

negative regulation of transforming growth factor beta2 production (ISO)

positive regulation of canonical Wnt signaling pathway (ISO)

positive regulation of gene expression (ISO)

positive regulation of insulin-like growth factor receptor signaling pathway (ISO)

positive regulation of keratinocyte proliferation (ISO)

positive regulation of melanin biosynthetic process (ISO)

positive regulation of melanosome transport (ISO)

regulation of hair cycle by canonical Wnt signaling pathway (ISO)

response to xenobiotic stimulus (IEP)

retina homeostasis (ISO)

Cellular Component

adherens junction (IBA,ISO)

catenin complex (IBA)

cell junction (ISO)

cytoplasm (IBA)

plasma membrane (ISO)

Molecular Function

cadherin binding (IBA)

calcium ion binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Multiple cadherin superfamily members with unique expression profiles are produced in rat testis.	Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
3.	Distinct CDH3 mutations cause ectodermal dysplasia, ectrodactyly, macular dystrophy (EEM syndrome).	Kjaer KW, etal., J Med Genet. 2005 Apr;42(4):292-8.
4.	Expression of P-cadherin distinct from that of E-cadherin in re-epithelialization in neonatal rat skin.	Koizumi M, etal., Dev Growth Differ. 2005 Feb;47(2):75-85.
5.	Expression and localization of P-, K-, and OB-cadherin in the prepubertal rat ovary.	Machell NH, etal., Mol Reprod Dev 2002 Feb;61(2):142-54.
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	Changes in the expression of P-cadherin in the normal, cryptorchid and busulphan-treated rat testis.	Pospechova K, etal., Int J Androl. 2007 Feb 12;.
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:10460003	PMID:12060406	PMID:15148305	PMID:15728677	PMID:15775979	PMID:21285403	PMID:22696062	PMID:23143461	PMID:23334344

Genomics

Comparative Map Data

Cdh3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	34,393,596 - 34,444,084 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	34,393,727 - 34,444,084 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	41,209,266 - 41,259,606 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	41,862,587 - 41,912,930 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	44,161,722 - 44,212,069 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	38,668,957 - 38,719,801 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	38,669,230 - 38,719,677 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	49,536,859 - 49,587,578 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	36,343,823 - 36,393,819 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	36,395,654 - 36,397,989 (+)	NCBI
Celera	19	33,820,490 - 33,870,862 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

CDH3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	68,645,310 - 68,733,771 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	68,636,189 - 68,727,468 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	68,679,213 - 68,734,195 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	67,236,277 - 67,290,443 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	67,236,276 - 67,290,442	NCBI
Celera	16	53,187,169 - 53,242,286 (+)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	54,551,120 - 54,605,916 (+)	NCBI		HuRef
CHM1_1	16	70,086,362 - 70,141,056 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	74,441,601 - 74,531,453 (+)	NCBI		T2T-CHM13v2.0

Cdh3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	107,237,484 - 107,283,543 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	107,237,523 - 107,283,929 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	106,510,852 - 106,556,911 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	106,510,891 - 106,557,297 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	109,034,791 - 109,080,808 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	109,400,020 - 109,446,037 (+)	NCBI		MGSCv36	mm8
Celera	8	110,734,945 - 110,781,298 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.16	NCBI

Cdh3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	7,938,495 - 7,986,231 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955484	7,937,847 - 7,985,418 (-)	NCBI	ChiLan1.0	ChiLan1.0

CDH3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	84,096,426 - 84,153,602 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	49,015,115 - 49,071,903 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	68,408,078 - 68,465,287 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	68,407,625 - 68,465,287 (+)	Ensembl	panpan1.1		panPan2

CDH3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	80,864,859 - 80,912,136 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	80,863,661 - 80,913,019 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	80,855,712 - 80,903,039 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	81,300,176 - 81,347,383 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	81,300,808 - 81,348,235 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	81,126,956 - 81,174,134 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	80,810,235 - 80,857,421 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	81,450,703 - 81,498,265 (-)	NCBI		UU_Cfam_GSD_1.0

Cdh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	40,634,712 - 40,682,648 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	18,906,493 - 18,955,072 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	18,908,031 - 18,954,402 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDH3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	18,191,664 - 18,235,862 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	18,190,971 - 18,236,184 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	16,844,456 - 16,853,923 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDH3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	58,717,600 - 58,775,033 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	58,717,597 - 58,775,339 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	21,455,596 - 21,513,438 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdh3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	17,616,940 - 17,658,548 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	17,616,296 - 17,659,021 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cdh3
249 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	86
Count of miRNA genes:	70
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000027273
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	1	36824771	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	1	36824771	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	36824771	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	1	36824771	Rat
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
724565	Tcas5	Tongue tumor susceptibility QTL 5	10.04		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	19	9977753	39654489	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	15114598	34521833	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	24817978	39654489	Rat
1354600	Salc2	Saline consumption QTL 2	9.91	0.001	drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	19	27530207	37947399	Rat
1354607	Gmadr1	Adrenal mass QTL 1	5.83		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	19	27530207	37947399	Rat
1354633	Bw28	Body weight QTL 28	6.04		body mass (VT:0001259)	body weight (CMO:0000012)	19	27530207	37947399	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	29322490	57337602	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	19	33838214	55283146	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	33838214	55283146	Rat

Markers in Region

AI010270

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	34,443,735 - 34,443,881 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	38,719,453 - 38,719,598	NCBI	Rnor6.0
Rnor_5.0	19	49,587,208 - 49,587,353	UniSTS	Rnor5.0
RGSC_v3.4	19	36,393,449 - 36,393,594	UniSTS	RGSC3.4
Celera	19	33,870,514 - 33,870,659	UniSTS
RH 3.4 Map	19	293.2	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		18	6	6	1	6			6	20	27	9
Low	3	15	36	26	18	26	1	1	66	15	14	2	1
Below cutoff		10	15	9		9	7	8	2				7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF177683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000027273 ⟹ ENSRNOP00000027273

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	34,393,727 - 34,444,084 (+)	Ensembl
Rnor_6.0 Ensembl	19	38,669,230 - 38,719,677 (+)	Ensembl

RefSeq Acc Id:

NM_053938 ⟹ NP_446390

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	34,393,727 - 34,444,084 (+)	NCBI
Rnor_6.0	19	38,669,558 - 38,719,801 (+)	NCBI
Rnor_5.0	19	49,536,859 - 49,587,578 (+)	NCBI
RGSC_v3.4	19	36,343,823 - 36,393,819 (+)	RGD
Celera	19	33,820,490 - 33,870,862 (+)	NCBI

Sequence:

show sequence

AGAGGTGAAGTGGATTGGGGGTTTTGTTTTGTTACATTTGTTCCATTGAAGCCAGAAACTGCGA
GAGCCACGGGGTACCTTTCAGAAGTAGTTCCAGAAGAGCAGGGAGGACGGAGGAGGGTACCGGG
GAGGACCTTTAGGAGCTTCGGGAGCGACTTCGGCAAGCTGGTCTGGACTCCACCTGCGAGGGGG
CGGGACCCTGTGACGTTTGACCAATCAGCAGCTACCTGAGCGCACCTGGCCTCCTCCCGCGGGC
TCTAGCGAGCCGCGTTGCTCAAAGCTGCACCGGGAGCTTAGCGGAACGCTTGGCTACCGTCGCG
GCAGCCTCCTCACCTCCCTTCAGTCATGGAGCTGCTTAGTGGGCCCCTGGTCTTCCTGCTCCTC
CTGCTCCAGGTTTGCTGGCTACGCAGCGTGGTCTCCGAGTCCTACCGGGAGGACTTCATCCGGG
AGGCTGGAGTGACCTTGGAGGTGGGAGGAACTGACCTGGAGCCGAGCCAAGCGCTAGAGAAAGA
GGCATTGGCTGGACACGAGGTGCTCGGTGCAGACAGTGGAGGAATCATTACACTGAATAGGGAG
ACAGTCCAGGGAGGGAAGGGTGTGATGAACTCCCCACCCTCACGCATCTTACGGAGACGAAAGA
GAGAGTGGGTGATGCCACCAATATCGGTCCCTGAGAATGGCAAAGGTCCTTTTCCTCAGAGGCT
GAATCAGCTTAAATCTAATAAGGACAGAGGCACCAAGCTTTTCTACAGCATCACGGGGCCTGGA
GCTGACAGTCCCCCTGAGGGAGTCTTCACCATAGAGAAGGAGACGGGCTGGCTGCTGTTGAATA
TGCCACTGGACAGGGAGAAAATTGTCAAGTATGAGCTTTTTGGCCACGCTGTATCTGAGAATGG
TGCGTCTGTAGAGGAGCCCATGAACATATCCATCATTGTGACAGATCAGAATGACAACAAGCCC
AAGTTCACTCAAGACACCTTCAGAGGGAGTGTTCCGGAGGGGGTAATGCCTGGCACTTCTGTGA
TGCAGGTGACAGCCACAGATGAGGACGACGCCATCAATACTTACAATGGGGTGGTGGCTTACTC
CATCCATAGCCAAGAGCCGAAGGAGCCACACGACCTCATGTTCACCATCCATAAAAGCACTGGG
ACTATTAGCGTCATCTCCAGTGGCCTGGATAGAGAGAAAGTCCCTGAGTACACACTGACCATCC
AGGCCACAGACATGGACGGAGACGGCTCTACCACAACAGCCGAGGCCGTAGTGCAGATCCTTGA
TACCAATGATAACGCTCCAGAGTTCCAGCCGCAAAAGTATGAGGCTTGGGTGCCTGAGAATGCA
GTGGGCCACGAGGTACAGAGGCTGACAGTGACCGATCTGGATTCCCCCAACTCACCGGCATGGC
GTGCCACCTACCACATTGTGGGAGGTGACGATGGGGATCATTTCACCGTGGCCACTCACCCAGA
GACCAACCAAGGCATCCTGACAACCAAGAAGGGTTTGGATTTTGAGGCTCAGAACCAACACACC
CTGTACATAGAAGTGACCAACGAGGCTTCCTTTGCAGTGAAGCTCCCGACTGCCACCGCCACCG
TGGTGGTCCATGTGGAAGATGTCAACGAGGCCCCTGTGTTTGTTCCACCTTCCAAGGTCATTGA
GGCCCAGGAAGGCATCTCTATTGGGGAACTGGTCTGTGTCTATACTGCACAGGACCCTGACAAG
GAGGAACAGAAGATCAGCTACAGCATCTTGAGAGACCCAGCCAGCTGGCTTGCTGTGGACCCGG
ACAGTGGTCAGATAACGGCTGCAGGCATCTTAGATCGTGAGGACGAGCAGTTTGTGAAAAACGA
CATCTACGAAGTCATGGTGTTGGCCACAGACAATGGAAACCCTCCCACCACCGGCACTGGGACC
CTCCTGCTAACACTTACTGACATCAATGACCATGGCCCAATCCCTGAACCTCGTCAGATCATCA
TCTGTAACCAAAGCCCCGTGCCTCAAGTGCTGAACATCACAGACAAGGACCTGTCCCCCAACTC
CTCCCCTTTCCAGGCCCAGCTCACACATGATTCAGATATCTACTGGATGGCAGAAGTCAGCGAG
AAAGGAGACACCGTGGCCTTGTCCCTGAAGAAGTTCCTGAAGCAAGACACATATGACTTGCACC
TTTCTTTGTCTGACCATGGCAACCGGGAACAGCTAACCATGATCAGGGCCACTGTGTGTGACTG
CCACGGCCAGGTGTTGAATGACTGCCCCAGACCCTGGAAAGGTGGCTTCATCCTCCCCGTCCTG
GGTGCTGTCCTGGCTCTACTGACCCTTCTTCTGGCGCTCCTTCTGTTGGTGAGAAAGAAGAGGA
AGGTCAAAGAGCCCCTTCTGCTCCCAGAGGATGACACTCGTGACAATGTCTTCTATTATGGAGA
AGAGGGTGGTGGCGAAGAGGACCAGGACTATGACATCACTCAACTCCACCGGGGACTAGAGGCC
AGGCCTGAGGTGGTTCTCCGCAACGACGTGGCACCAACCTTCATCCCCACCCCCATGTACCGCC
CCCGGCCCGCCAACCCAGATGAAATCGGCAACTTCATCATCGAGAACCTGAAAGCTGCCAACAC
AGACCCCACTGCTCCTCCCTACGACTCCCTGCTGGTGTTTGACTACGAGGGCAGTGGCTCTGAT
GCTGCCTCCCTGAGCTCCCTCACCTCCTCCACCTCTGATCAGGACCAGGACTACAACTACCTTA
CCGAGTGGGGAAGTCGATTCAAGAAACTGGCTGACATGTATGGTGGCGGTGAGGATGACTAGAC
TGGCCGGCCATGCTGTCCAGGCAAGAACTACAGACAGGTCACAGCAGCATCTCAGGGGAGCTCT
CACTCCTGCTCCTGAGGACTCTGAAGCTCGCCAGGAAGTCGCCCGCAAAGCAGGCTGCATCTGA
CATGAAGGCTAGACTGTGAGCCTTTCAAATGGGAGGATGTGACTCTGACTTCAACACTGATCCC
CCTCAGCCGATGCTGAGCCCTCAGAATGGACTGTCTAGAGGTCTCCCGCCTGCCACACAGGGCT
CAGGGCAGAACTTGCTCTGATGCCCTTGGTGACTTTCTCCACTTGAATGGCTCTCTCTTTAGAA
AGAGACCTCTCACTAAGGCCCCTTTTTCCTTTAATGCAGTTTTCATAAAGAGGCTCAGGGTGGG
GCAGGGTGCAGACATCAGTCTCCCTTCAGGCCCTCCAGAAGAGAAGCCTACAGGGCACTGGCCC
TGGTACATTTCTCTGATCTCCAGGTCTTGAGGCCTCACATTGGGAGGGATAAATGCTTTTTTTT
TTTTTTTTAATGAGTATATCTAAGTTGTCTTGTATTTTTTTATTTTCCCTGATGTGTGCTGTAG
ATGGAGAGTGATGACAATCGTGTAAATGTACTAGAATTTTTTTATTAAAATGAACTTTTTCCCA
GA

hide sequence

RefSeq Acc Id:

XM_006255559 ⟹ XP_006255621

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	34,393,596 - 34,444,084 (+)	NCBI
Rnor_6.0	19	38,668,957 - 38,719,801 (+)	NCBI
Rnor_5.0	19	49,536,859 - 49,587,578 (+)	NCBI

Sequence:

show sequence

CTCTGACCTCCACTTGGGTGCAGTGGGTCATCACACATATAAAGATAACTAATAAGGAAAACAT
CTCCATTGTTTGCATTTAACATAAAATTAAAGGAACATTTATATTTGAGGAAGAAAATATTTAT
ATTGGGGGTGCCAGAAATAATGGAGCTAAGTTGGGGGTGCCAGAAATAATGGAGCTAATAACAA
ATAACTTGTTCCCTACCTCAAGCCCTTTGAAGTTACTATGGCTTCCAAACTCTGGGGCTTTCTG
TACTAGCTTCCTTCCACTTGTTCAGCTGCAAACGGAAGTAACTATTCTCTCAAACGTATATCAG
ATCCCTTACCGCGGTCCTTTGAGACCTCGATGCTACTTTTAAAACCCCAGTGCTTCCCCCGGGA
TAGTGTAGGAGGTGGAGAAAGTGGCAGAGGGCAGACCCCGCTATAGCTGGTGTAAAGACACGCC
CTGCCTCCATCAAAGCTTTGAACACAAGCGCCTCCGGCAGCATGAATGAGGAGCCTCTGTTTTT
TTGTCGGGTTTCAGATGAGTCTCCACTTTTTTTTTTTTTCCGCTGTAGCTGCCAGCAATGGAAT
ATTTGTCTTCCCGTGCTGCAGAGGCAGAGGTTTGCTGGCTACGCAGCGTGGTCTCCGAGTCCTA
CCGGGAGGACTTCATCCGGGAGGCTGGAGTGACCTTGGAGGTGGGAGGAACTGACCTGGAGCCG
AGCCAAGCGCTAGAGAAAGAGGCATTGGCTGGACACGAGGTGCTCGGTGCAGACAGTGGAGGAA
TCATTACACTGAATAGGGAGACAGTCCAGGGAGGGAAGGGTGTGATGAACTCCCCACCCTCACG
CATCTTACGGAGACGAAAGAGAGAGTGGGTGATGCCACCAATATCGGTCCCTGAGAATGGCAAA
GGTCCTTTTCCTCAGAGGCTGAATCAGCTTAAATCTAATAAGGACAGAGGCACCAAGCTTTTCT
ACAGCATCACGGGGCCTGGAGCTGACAGTCCCCCTGAGGGAGTCTTCACCATAGAGAAGGAGAC
GGGCTGGCTGCTGTTGAATATGCCACTGGACAGGGAGAAAATTGTCAAGTATGAGCTTTTTGGC
CACGCTGTATCTGAGAATGGTGCGTCTGTAGAGGAGCCCATGAACATATCCATCATTGTGACAG
ATCAGAATGACAACAAGCCCAAGTTCACTCAAGACACCTTCAGAGGGAGTGTTCCGGAGGGGGT
AATGCCTGGCACTTCTGTGATGCAGGTGACAGCCACAGATGAGGACGACGCCATCAATACTTAC
AATGGGGTGGTGGCTTACTCCATCCATAGCCAAGAGCCGAAGGAGCCACACGACCTCATGTTCA
CCATCCATAAAAGCACTGGGACTATTAGCGTCATCTCCAGTGGCCTGGATAGAGAGAAAGTCCC
TGAGTACACACTGACCATCCAGGCCACAGACATGGACGGAGACGGCTCTACCACAACAGCCGAG
GCCGTAGTGCAGATCCTTGATACCAATGATAACGCTCCAGAGTTCCAGCCGCAAAAGTATGAGG
CTTGGGTGCCTGAGAATGCAGTGGGCCACGAGGTACAGAGGCTGACAGTGACCGATCTGGATTC
CCCCAACTCACCGGCATGGCGTGCCACCTACCACATTGTGGGAGGTGACGATGGGGATCATTTC
ACCGTGGCCACTCACCCAGAGACCAACCAAGGCATCCTGACAACCAAGAAGGGTTTGGATTTTG
AGGCTCAGAACCAACACACCCTGTACATAGAAGTGACCAACGAGGCTTCCTTTGCAGTGAAGCT
CCCGACTGCCACCGCCACCGTGGTGGTCCATGTGGAAGATGTCAACGAGGCCCCTGTGTTTGTT
CCACCTTCCAAGGTCATTGAGGCCCAGGAAGGCATCTCTATTGGGGAACTGGTCTGTGTCTATA
CTGCACAGGACCCTGACAAGGAGGAACAGAAGATCAGCTACAGCATCTTGAGAGACCCAGCCAG
CTGGCTTGCTGTGGACCCGGACAGTGGTCAGATAACGGCTGCAGGCATCTTAGATCGTGAGGAC
GAGCAGTTTGTGAAAAACGACATCTACGAAGTCATGGTGTTGGCCACAGACAATGGAAACCCTC
CCACCACCGGCACTGGGACCCTCCTGCTAACACTTACTGACATCAATGACCATGGCCCAATCCC
TGAACCTCGTCAGATCATCATCTGTAACCAAAGCCCCGTGCCTCAAGTGCTGAACATCACAGAC
AAGGACCTGTCCCCCAACTCCTCCCCTTTCCAGGCCCAGCTCACACATGATTCAGATATCTACT
GGATGGCAGAAGTCAGCGAGAAAGGAGACACCGTGGCCTTGTCCCTGAAGAAGTTCCTGAAGCA
AGACACATATGACTTGCACCTTTCTTTGTCTGACCATGGCAACCGGGAACAGCTAACCATGATC
AGGGCCACTGTGTGTGACTGCCACGGCCAGGTGTTGAATGACTGCCCCAGACCCTGGAAAGGTG
GCTTCATCCTCCCCGTCCTGGGTGCTGTCCTGGCTCTACTGACCCTTCTTCTGGCGCTCCTTCT
GTTGGTGAGAAAGAAGAGGAAGGTCAAAGAGCCCCTTCTGCTCCCAGAGGATGACACTCGTGAC
AATGTCTTCTATTATGGAGAAGAGGGTGGTGGCGAAGAGGACCAGGACTATGACATCACTCAAC
TCCACCGGGGACTAGAGGCCAGGCCTGAGGTGGTTCTCCGCAACGACGTGGCACCAACCTTCAT
CCCCACCCCCATGTACCGCCCCCGGCCCGCCAACCCAGATGAAATCGGCAACTTCATCATCGAG
AACCTGAAAGCTGCCAACACAGACCCCACTGCTCCTCCCTACGACTCCCTGCTGGTGTTTGACT
ACGAGGGCAGTGGCTCTGATGCTGCCTCCCTGAGCTCCCTCACCTCCTCCACCTCTGATCAGGA
CCAGGACTACAACTACCTTACCGAGTGGGGAAGTCGATTCAAGAAACTGGCTGACATGTATGGT
GGCGGTGAGGATGACTAGACTGGCCGGCCATGCTGTCCAGGCAAGAACTACAGACAGGTCACAG
CAGCATCTCAGGGGAGCTCTCACTCCTGCTCCTGAGGACTCTGAAGCTCGCCAGGAAGTCGCCC
GCAAAGCAGGCTGCATCTGACATGAAGGCTAGACTGTGAGCCTTTCAAATGGGAGGATGTGACT
CTGACTTCAACACTGATCCCCCTCAGCCGATGCTGAGCCCTCAGAATGGACTGTCTAGAGGTCT
CCCGCCTGCCACACAGGGCTCAGGGCAGAACTTGCTCTGATGCCCTTGGTGACTTTCTCCACTT
GAATGGCTCTCTCTTTAGAAAGAGACCTCTCACTAAGGCCCCTTTTTCCTTTAATGCAGTTTTC
ATAAAGAGGCTCAGGGTGGGGCAGGGTGCAGACATCAGTCTCCCTTCAGGCCCTCCAGAAGAGA
AGCCTACAGGGCACTGGCCCTGGTACATTTCTCTGATCTCCAGGTCTTGAGGCCTCACATTGGG
AGGGATAAATGCTTTTTTTTTTTTTTTTAATGAGTATATCTAAGTTGTCTTGTATTTTTTTATT
TTCCCTGATGTGTGCTGTAGATGGAGAGTGATGACAATCGTGTAAATGTACTAGAATTTTTTTA
TTAAAATGAACTTTTTCCCAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_446390	(Get FASTA)	NCBI Sequence Viewer
	XP_006255621	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF87058	(Get FASTA)	NCBI Sequence Viewer
	EDL92450	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027273
	ENSRNOP00000027273.7

RefSeq Acc Id:	NP_446390 ⟸ NM_053938
- Peptide Label:	precursor
- UniProtKB:	F1LMI3 (UniProtKB/TrEMBL), A6IYX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLSGPLVFLLLLLQVCWLRSVVSESYREDFIREAGVTLEVGGTDLEPSQALEKEALAGHEVL GADSGGIITLNRETVQGGKGVMNSPPSRILRRRKREWVMPPISVPENGKGPFPQRLNQLKSNKD RGTKLFYSITGPGADSPPEGVFTIEKETGWLLLNMPLDREKIVKYELFGHAVSENGASVEEPMN ISIIVTDQNDNKPKFTQDTFRGSVPEGVMPGTSVMQVTATDEDDAINTYNGVVAYSIHSQEPKE PHDLMFTIHKSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAEAVVQILDTNDNAPEF QPQKYEAWVPENAVGHEVQRLTVTDLDSPNSPAWRATYHIVGGDDGDHFTVATHPETNQGILTT KKGLDFEAQNQHTLYIEVTNEASFAVKLPTATATVVVHVEDVNEAPVFVPPSKVIEAQEGISIG ELVCVYTAQDPDKEEQKISYSILRDPASWLAVDPDSGQITAAGILDREDEQFVKNDIYEVMVLA TDNGNPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLT HDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVLNDC PRPWKGGFILPVLGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQ DYDITQLHRGLEARPEVVLRNDVAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYD SLLVFDYEGSGSDAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD hide sequence

RefSeq Acc Id:

XP_006255621 ⟸ XM_006255559

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEYLSSRAAEAEVCWLRSVVSESYREDFIREAGVTLEVGGTDLEPSQALEKEALAGHEVLGADS
GGIITLNRETVQGGKGVMNSPPSRILRRRKREWVMPPISVPENGKGPFPQRLNQLKSNKDRGTK
LFYSITGPGADSPPEGVFTIEKETGWLLLNMPLDREKIVKYELFGHAVSENGASVEEPMNISII
VTDQNDNKPKFTQDTFRGSVPEGVMPGTSVMQVTATDEDDAINTYNGVVAYSIHSQEPKEPHDL
MFTIHKSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAEAVVQILDTNDNAPEFQPQK
YEAWVPENAVGHEVQRLTVTDLDSPNSPAWRATYHIVGGDDGDHFTVATHPETNQGILTTKKGL
DFEAQNQHTLYIEVTNEASFAVKLPTATATVVVHVEDVNEAPVFVPPSKVIEAQEGISIGELVC
VYTAQDPDKEEQKISYSILRDPASWLAVDPDSGQITAAGILDREDEQFVKNDIYEVMVLATDNG
NPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSD
IYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVLNDCPRPW
KGGFILPVLGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDI
TQLHRGLEARPEVVLRNDVAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLV
FDYEGSGSDAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD

hide sequence

RefSeq Acc Id:

ENSRNOP00000027273 ⟸ ENSRNOT00000027273

Protein Domains

Cadherin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LMI3-F1-model_v2	AlphaFold	F1LMI3	1-822	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701112

Promoter ID:

EPDNEW_R11636

Type:

multiple initiation site

Name:

Cdh3_1

Description:

cadherin 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	38,669,834 - 38,669,894	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621089	AgrOrtholog
BioCyc Gene	G2FUF-5778	BioCyc
Ensembl Genes	ENSRNOG00000020129	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027273	ENTREZGENE
	ENSRNOT00000027273.8	UniProtKB/TrEMBL
Gene3D-CATH	4.10.900.10	UniProtKB/TrEMBL
	Cadherins	UniProtKB/TrEMBL
InterPro	Cadherin	UniProtKB/TrEMBL
	Cadherin	UniProtKB/TrEMBL
	Cadherin-like	UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/TrEMBL
	Cadherin_cytoplasmic-dom	UniProtKB/TrEMBL
	Catenin_binding_dom	UniProtKB/TrEMBL
KEGG Report	rno:116777	UniProtKB/TrEMBL
NCBI Gene	116777	ENTREZGENE
PANTHER	CADHERIN-3	UniProtKB/TrEMBL
	PTHR24027	UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/TrEMBL
PhenoGen	Cdh3	PhenoGen
PRINTS	CADHERIN	UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020129	RatGTEx
SMART	SM00112	UniProtKB/TrEMBL
Superfamily-SCOP	Cadherin	UniProtKB/TrEMBL
UniProt	A6IYX2	ENTREZGENE, UniProtKB/TrEMBL
	F1LMI3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-11-05	Cdh3	cadherin 3	Cdh3	cadherin 3, type 1, P-cadherin (placental)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Cdh3	cadherin 3, type 1, P-cadherin (placental)			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Cdh3	cadherin 3, type 1, P-cadherin (placental)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in granulosa cells, thecal/interstitial cells, and also in oocytes of primordial follicles	68759

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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