Cdh3 (cadherin 3) - Rat Genome Database

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Gene: Cdh3 (cadherin 3) Rattus norvegicus
Analyze
Symbol: Cdh3
Name: cadherin 3
RGD ID: 621089
Description: Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in response to xenobiotic stimulus. Predicted to be located in cell junction and plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction and cytoplasm. Human ortholog(s) of this gene implicated in congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome. Orthologous to human CDH3 (cadherin 3); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cadherin 3, type 1, P-cadherin (placental); cadherin-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81951,303,414 - 51,353,900 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1951,300,083 - 51,354,257 (+)EnsemblGRCr8
mRatBN7.21934,393,596 - 34,444,084 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,393,727 - 34,444,084 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1941,209,266 - 41,259,606 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,862,587 - 41,912,930 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01944,161,722 - 44,212,069 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01938,668,957 - 38,719,801 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,669,230 - 38,719,677 (+)Ensemblrn6Rnor6.0
Rnor_5.01949,536,859 - 49,587,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41936,343,823 - 36,393,819 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1933,820,490 - 33,870,862 (+)NCBICelera
RGSC_v3.11936,395,654 - 36,397,989 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-acetamidofluorene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amosite asbestos  (ISO)
apocynin  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (EXP)
cytarabine  (ISO)
deguelin  (ISO)
Deoxycorticosterone acetate  (ISO)
dibutyl phthalate  (ISO)
diiodine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (EXP)
glycidol  (EXP)
hexadecanoic acid  (ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
inulin  (ISO)
isobutanol  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
puromycin  (ISO)
rofecoxib  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sotorasib  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (IBA,ISO)
catenin complex  (IBA)
cell junction  (IEA,ISO)
cytoplasm  (IBA)
membrane  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Multiple cadherin superfamily members with unique expression profiles are produced in rat testis. Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
3. Distinct CDH3 mutations cause ectodermal dysplasia, ectrodactyly, macular dystrophy (EEM syndrome). Kjaer KW, etal., J Med Genet. 2005 Apr;42(4):292-8.
4. Expression of P-cadherin distinct from that of E-cadherin in re-epithelialization in neonatal rat skin. Koizumi M, etal., Dev Growth Differ. 2005 Feb;47(2):75-85.
5. Expression and localization of P-, K-, and OB-cadherin in the prepubertal rat ovary. Machell NH, etal., Mol Reprod Dev 2002 Feb;61(2):142-54.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Changes in the expression of P-cadherin in the normal, cryptorchid and busulphan-treated rat testis. Pospechova K, etal., Int J Androl. 2007 Feb 12;.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10460003   PMID:12060406   PMID:15148305   PMID:15728677   PMID:15775979   PMID:21285403   PMID:22696062   PMID:23143461   PMID:23334344  


Genomics

Comparative Map Data
Cdh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81951,303,414 - 51,353,900 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1951,300,083 - 51,354,257 (+)EnsemblGRCr8
mRatBN7.21934,393,596 - 34,444,084 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,393,727 - 34,444,084 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1941,209,266 - 41,259,606 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,862,587 - 41,912,930 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01944,161,722 - 44,212,069 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01938,668,957 - 38,719,801 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,669,230 - 38,719,677 (+)Ensemblrn6Rnor6.0
Rnor_5.01949,536,859 - 49,587,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41936,343,823 - 36,393,819 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1933,820,490 - 33,870,862 (+)NCBICelera
RGSC_v3.11936,395,654 - 36,397,989 (+)NCBI
Cytogenetic Map19q12NCBI
CDH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381668,645,310 - 68,733,771 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1668,636,189 - 68,727,468 (+)Ensemblhg38GRCh38
GRCh371668,679,213 - 68,734,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361667,236,277 - 67,290,443 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341667,236,276 - 67,290,442NCBI
Celera1653,187,169 - 53,242,286 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1654,551,120 - 54,605,916 (+)NCBIHuRef
CHM1_11670,086,362 - 70,141,056 (+)NCBICHM1_1
T2T-CHM13v2.01674,441,601 - 74,531,453 (+)NCBIT2T-CHM13v2.0
Cdh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398107,237,484 - 107,283,543 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8107,237,523 - 107,283,929 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388106,510,852 - 106,556,911 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8106,510,891 - 106,557,297 (+)Ensemblmm10GRCm38
MGSCv378109,034,791 - 109,080,808 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368109,400,020 - 109,446,037 (+)NCBIMGSCv36mm8
Celera8110,734,945 - 110,781,298 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.16NCBI
Cdh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554847,938,495 - 7,986,231 (-)Ensembl
ChiLan1.0NW_0049554847,937,847 - 7,985,418 (-)NCBIChiLan1.0ChiLan1.0
CDH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21878,185,107 - 78,242,221 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11684,096,426 - 84,153,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01649,015,115 - 49,071,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11668,408,078 - 68,465,287 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1668,407,625 - 68,465,287 (+)EnsemblpanPan2panpan1.1
CDH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1580,864,859 - 80,912,136 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl580,863,661 - 80,913,019 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha580,855,712 - 80,903,039 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0581,300,176 - 81,347,383 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl581,300,808 - 81,348,235 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,126,956 - 81,174,134 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0580,810,235 - 80,857,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0581,450,703 - 81,498,265 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934940,634,712 - 40,682,648 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,906,493 - 18,955,072 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,908,031 - 18,954,402 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl618,191,664 - 18,235,862 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1618,190,971 - 18,236,184 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2616,844,456 - 16,853,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1558,717,600 - 58,775,033 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl558,717,597 - 58,775,339 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604721,455,596 - 21,513,438 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474617,616,940 - 17,658,548 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474617,616,296 - 17,659,021 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdh3
267 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:70
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000027273
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat

Markers in Region
AI010270  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21934,443,735 - 34,443,881 (+)MAPPERmRatBN7.2
Rnor_6.01938,719,453 - 38,719,598NCBIRnor6.0
Rnor_5.01949,587,208 - 49,587,353UniSTSRnor5.0
RGSC_v3.41936,393,449 - 36,393,594UniSTSRGSC3.4
Celera1933,870,514 - 33,870,659UniSTS
RH 3.4 Map19293.2UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 67 149 91 90 59 29 59 6 288 124 8 127 81 92 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000027273   ⟹   ENSRNOP00000027273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1951,303,556 - 51,354,257 (+)Ensembl
mRatBN7.2 Ensembl1934,393,727 - 34,444,084 (+)Ensembl
Rnor_6.0 Ensembl1938,669,230 - 38,719,677 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131260   ⟹   ENSRNOP00000105187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1951,300,083 - 51,353,900 (+)Ensembl
RefSeq Acc Id: NM_053938   ⟹   NP_446390
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,303,556 - 51,353,900 (+)NCBI
mRatBN7.21934,393,727 - 34,444,084 (+)NCBI
Rnor_6.01938,669,558 - 38,719,801 (+)NCBI
Rnor_5.01949,536,859 - 49,587,578 (+)NCBI
RGSC_v3.41936,343,823 - 36,393,819 (+)RGD
Celera1933,820,490 - 33,870,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006255559   ⟹   XP_006255621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,303,414 - 51,353,900 (+)NCBI
mRatBN7.21934,393,596 - 34,444,084 (+)NCBI
Rnor_6.01938,668,957 - 38,719,801 (+)NCBI
Rnor_5.01949,536,859 - 49,587,578 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_446390 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255621 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF87058 (Get FASTA)   NCBI Sequence Viewer  
  EDL92450 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027273
  ENSRNOP00000027273.7
  ENSRNOP00000105187
RefSeq Acc Id: NP_446390   ⟸   NM_053938
- Peptide Label: precursor
- UniProtKB: F1LMI3 (UniProtKB/TrEMBL),   A6IYX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255621   ⟸   XM_006255559
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000027273   ⟸   ENSRNOT00000027273
Ensembl Acc Id: ENSRNOP00000105187   ⟸   ENSRNOT00000131260
Protein Domains
Cadherin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LMI3-F1-model_v2 AlphaFold F1LMI3 1-822 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701112
Promoter ID:EPDNEW_R11636
Type:multiple initiation site
Name:Cdh3_1
Description:cadherin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01938,669,834 - 38,669,894EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621089 AgrOrtholog
BioCyc Gene G2FUF-5778 BioCyc
Ensembl Genes ENSRNOG00000020129 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027273 ENTREZGENE
  ENSRNOT00000027273.8 UniProtKB/TrEMBL
  ENSRNOT00000131260 ENTREZGENE
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin UniProtKB/TrEMBL
  Cadherin-like UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin_binding_dom UniProtKB/TrEMBL
KEGG Report rno:116777 UniProtKB/TrEMBL
NCBI Gene 116777 ENTREZGENE
PANTHER CADHERIN-3 UniProtKB/TrEMBL
  PTHR24027 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PhenoGen Cdh3 PhenoGen
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020129 RatGTEx
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP Cadherin UniProtKB/TrEMBL
UniProt A6IYX2 ENTREZGENE, UniProtKB/TrEMBL
  F1LMI3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-05 Cdh3  cadherin 3  Cdh3  cadherin 3, type 1, P-cadherin (placental)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cdh3  cadherin 3, type 1, P-cadherin (placental)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cdh3  cadherin 3, type 1, P-cadherin (placental)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in granulosa cells, thecal/interstitial cells, and also in oocytes of primordial follicles 68759