Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tk2 (thymidine kinase 2) Rattus norvegicus
Analyze
Symbol: Tk2
Name: thymidine kinase 2
Description: Exhibits deoxycytidine kinase activity and thymidine kinase activity. Involved in deoxycytidine metabolic process and thymidine metabolic process. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in chronic progressive external ophthalmoplegia and mitochondrial DNA depletion syndrome 2. Orthologous to human TK2 (thymidine kinase 2); PARTICIPATES IN pyrimidine metabolic pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC291824; thymidine kinase 2, mitochondrial
Orthologs:
Homo sapiens (human) : TK2 (thymidine kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Tk2 (thymidine kinase 2, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tk2 (thymidine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TK2 (thymidine kinase 2)
Canis lupus familiaris (dog) : TK2 (thymidine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tk2 (thymidine kinase 2)
Sus scrofa (pig) : TK2 (thymidine kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.019917,203 - 939,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl19917,203 - 939,221 (+)Ensembl
Rnor_5.019918,115 - 940,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419667,538 - 689,556 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.119667,549 - 687,995 (+)NCBI
Celera19704,113 - 726,111 (+)NCBICelera
Cytogenetic Map19p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309279
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.