Phb1l2 (prohibitin 1 like 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Phb1l2 (prohibitin 1 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Phb1l2
Name: prohibitin 1 like 2
RGD ID: 1584151
Description: Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC688815; Phb1l1; prohibitin 1 like 1; prohibitin 1-like; prohibitin-like; similar to prohibitin
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8198,700,474 - 8,702,329 (+)NCBIGRCr8
mRatBN7.2198,695,127 - 8,696,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl198,695,215 - 8,696,228 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0199,111,053 - 9,112,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,112,020 - 9,112,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,096,317 - 9,098,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,122,916 - 9,123,840 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera198,603,279 - 8,605,175 (+)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Variants

.
Variants in Phb1l2
7 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat

Markers in Region
RH127963  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19p13UniSTS
Cytogenetic MapXq14UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map6q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 3 27 58 53 50 28 23 28 6 135 68 43 30 47 22

Sequence


Ensembl Acc Id: ENSRNOT00000083521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl198,695,215 - 8,696,228 (+)Ensembl
Rnor_6.0 Ensembl199,112,020 - 9,112,820 (+)Ensembl
RefSeq Acc Id: XM_039098130   ⟹   XP_038954058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8198,700,474 - 8,702,329 (+)NCBI
mRatBN7.2198,695,127 - 8,696,208 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038954058 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082912.1
RefSeq Acc Id: XP_038954058   ⟸   XM_039098130
- UniProtKB: A0A8I5ZUY9 (UniProtKB/TrEMBL),   A6HHC9 (UniProtKB/TrEMBL)
Protein Domains
Band

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-6566 BioCyc
Ensembl Genes ENSRNOG00000060310 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083521.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.479.30 UniProtKB/TrEMBL
InterPro Band_7 UniProtKB/TrEMBL
  Band_7/SPFH_dom_sf UniProtKB/TrEMBL
  Prohibitin UniProtKB/TrEMBL
NCBI Gene 688815 ENTREZGENE
PANTHER PROHIBITIN UniProtKB/TrEMBL
  PTHR23222 UniProtKB/TrEMBL
Pfam Band_7 UniProtKB/TrEMBL
PhenoGen Phb1l2 PhenoGen
PRINTS PROHIBITIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000060310 RatGTEx
SMART PHB UniProtKB/TrEMBL
Superfamily-SCOP SSF117892 UniProtKB/TrEMBL
UniProt A0A8I5ZUY9 ENTREZGENE, UniProtKB/TrEMBL
  A6HHC9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Phb1l2  prohibitin 1 like 2  Phb1l1  prohibitin 1 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Phb1l1  prohibitin 1 like 1  LOC688815  similar to prohibitin  Symbol and Name Changed 1299863 APPROVED
2008-01-09 LOC688815  similar to prohibitin  LOC682174  similar to prohibitin  Data merged from RGD:1586914 1643240 APPROVED
2006-11-19 LOC688815  similar to prohibitin      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682174  similar to prohibitin      Symbol and Name status set to provisional 70820 PROVISIONAL