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Gene: Dnase2 (deoxyribonuclease 2, lysosomal) Rattus norvegicus
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Symbol: Dnase2
Name: deoxyribonuclease 2, lysosomal
Description: Exhibits endodeoxyribonuclease activity. Predicted to be involved in apoptotic DNA fragmentation. Predicted to localize to lysosome. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acid DNase; deoxyribonuclease II; deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; Dnase2a; lysosomal DNase II
Orthologs:
Homo sapiens (human) : DNASE2 (deoxyribonuclease 2, lysosomal)  HGNC  Alliance
Mus musculus (house mouse) : Gm38426 (predicted gene, 38426)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Dnase2 (deoxyribonuclease 2, lysosomal)
Pan paniscus (bonobo/pygmy chimpanzee) : DNASE2 (deoxyribonuclease 2, lysosomal)
Canis lupus familiaris (dog) : DNASE2 (deoxyribonuclease 2, lysosomal)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnase2 (deoxyribonuclease 2, lysosomal)
Sus scrofa (pig) : DNASE2 (deoxyribonuclease 2, lysosomal)
Chlorocebus sabaeus (African green monkey) : DNASE2 (deoxyribonuclease 2, lysosomal)
Heterocephalus glaber (naked mole-rat) : Dnase2 (deoxyribonuclease 2, lysosomal)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01926,022,855 - 26,025,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,022,849 - 26,025,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,998,478 - 37,001,146 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,900,949 - 24,903,617 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,905,774 - 24,908,443 (-)NCBI
Celera1922,801,629 - 22,804,297 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dnase2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621457
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.