Ces1dl1 (carboxylesterase 1D like 1) - Rat Genome Database

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Gene: Ces1dl1 (carboxylesterase 1D like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ces1dl1 (Ensembl: LOC291863)
Name: carboxylesterase 1D like 1 (Ensembl:carboxylesterase-like)
RGD ID: 1359640
Description: Enables retinyl-palmitate esterase activity. Predicted to be involved in acylglycerol catabolic process. Located in intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: carboxylesterase-like; LOC291863
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81938,444,294 - 38,476,011 (+)NCBIGRCr8
mRatBN7.21922,560,685 - 22,592,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1922,560,770 - 22,592,351 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1923,947,688 - 23,979,280 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01929,142,209 - 29,173,799 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,105,047 - 32,136,641 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
RGSC_v3.11914,933,380 - 14,971,905 (+)NCBI
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Identification of microsomal rat liver carboxylesterases and their activity with retinyl palmitate. Sanghani SP, etal., Eur J Biochem 2002 Sep;269(18):4387-98.
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Variants

.
Variants in Ces1dl1
313 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat

Markers in Region
RH133410  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21922,592,007 - 22,592,189 (+)MAPPERmRatBN7.2
mRatBN7.21913,911,691 - 13,911,873 (+)MAPPERmRatBN7.2
Rnor_6.01915,239,484 - 15,239,665NCBIRnor6.0
Rnor_5.01926,336,763 - 26,336,944UniSTSRnor5.0
RGSC_v3.41914,966,739 - 14,966,920UniSTSRGSC3.4
Celera1913,843,325 - 13,843,506UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map19p11UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000021812   ⟹   ENSRNOP00000021812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1922,560,770 - 22,592,351 (+)Ensembl
RefSeq Acc Id: NM_001013889   ⟹   NP_001013911
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,444,424 - 38,476,011 (+)NCBI
mRatBN7.21922,560,770 - 22,592,355 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097560   ⟹   XP_038953488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,444,294 - 38,476,011 (+)NCBI
mRatBN7.21922,560,691 - 22,592,355 (+)NCBI
RefSeq Acc Id: XM_039097561   ⟹   XP_038953489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,444,294 - 38,476,011 (+)NCBI
mRatBN7.21922,560,691 - 22,592,355 (+)NCBI
RefSeq Acc Id: XR_005496625
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,444,294 - 38,471,802 (+)NCBI
mRatBN7.21922,560,685 - 22,588,146 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001013911 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953488 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953489 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78681 (Get FASTA)   NCBI Sequence Viewer  
  EDL86195 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021812
  ENSRNOP00000021812.6
RefSeq Acc Id: XP_038953489   ⟸   XM_039097561
- Peptide Label: isoform X2
- UniProtKB: Q9R135 (UniProtKB/Swiss-Prot),   Q9QUX7 (UniProtKB/Swiss-Prot),   Q91YG2 (UniProtKB/Swiss-Prot),   Q6P785 (UniProtKB/Swiss-Prot),   Q64574 (UniProtKB/Swiss-Prot),   P16303 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953488   ⟸   XM_039097560
- Peptide Label: isoform X1
- UniProtKB: Q9R135 (UniProtKB/Swiss-Prot),   Q9QUX7 (UniProtKB/Swiss-Prot),   Q91YG2 (UniProtKB/Swiss-Prot),   Q6P785 (UniProtKB/Swiss-Prot),   Q64574 (UniProtKB/Swiss-Prot),   P16303 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001013911   ⟸   NM_001013889
- Peptide Label: precursor
- UniProtKB: Q9R135 (UniProtKB/Swiss-Prot),   Q9QUX7 (UniProtKB/Swiss-Prot),   Q91YG2 (UniProtKB/Swiss-Prot),   Q6P785 (UniProtKB/Swiss-Prot),   Q64574 (UniProtKB/Swiss-Prot),   P16303 (UniProtKB/Swiss-Prot),   Q68G49 (UniProtKB/TrEMBL),   G3V822 (UniProtKB/TrEMBL),   A0A9K3Y765 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021812   ⟸   ENSRNOT00000021812
Protein Domains
Carboxylesterase type B

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-6177 BioCyc
BioCyc Pathway PWY-6857 [retinol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6857 BioCyc
Ensembl Genes ENSRNOG00000015519 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021812 ENTREZGENE
  ENSRNOT00000021812.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7123712 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/TrEMBL
  CarbesteraseB UniProtKB/TrEMBL
  Carboxylesterase_B_AS UniProtKB/TrEMBL
  Carboxylesterase_B_CS UniProtKB/TrEMBL
KEGG Report rno:291863 UniProtKB/TrEMBL
MGC_CLONE MGC:93042 IMAGE-MGC_LOAD
NCBI Gene 291863 ENTREZGENE
PANTHER CARBOXYLESTERASE UniProtKB/TrEMBL
  LIVER CARBOXYLESTERASE 1-RELATED UniProtKB/TrEMBL
Pfam COesterase UniProtKB/TrEMBL
PhenoGen Ces1dl1 PhenoGen
PROSITE CARBOXYLESTERASE_B_1 UniProtKB/TrEMBL
  CARBOXYLESTERASE_B_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015519 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A9K3Y765 ENTREZGENE, UniProtKB/TrEMBL
  G3V822 ENTREZGENE
  P16303 ENTREZGENE
  Q64574 ENTREZGENE
  Q68G49 ENTREZGENE, UniProtKB/TrEMBL
  Q6P785 ENTREZGENE
  Q91YG2 ENTREZGENE
  Q9QUX7 ENTREZGENE
  Q9R135 ENTREZGENE
UniProt Secondary G3V822 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ces1dl1  carboxylesterase 1D like 1  LOC291863  carboxylesterase-like  Symbol and Name Changed 1299863 APPROVED
2005-07-29 LOC291863  carboxylesterase-like      Symbol and Name status set to provisional 70820 PROVISIONAL