Ces2el1 (carboxylesterase 2E like 1) - Rat Genome Database

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Gene: Ces2el1 (carboxylesterase 2E like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ces2el1 (Ensembl: LOC679368)
Name: carboxylesterase 2E like 1 (Ensembl:similar to carboxylesterase 5)
RGD ID: 1587637
Description: Predicted to enable carboxylesterase activity. Orthologous to human CES2 (carboxylesterase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07007146.1; LOC102551636; LOC688542; pyrethroid hydrolase Ces2e; pyrethroid hydrolase Ces2e-like; similar to carboxylesterase 5; uncharacterized LOC102551636
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81934,976 - 44,238 (-)NCBIGRCr8
mRatBN7.21928,516 - 37,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1928,520 - 37,732 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01282,714,617 - 282,733,287 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1282,723,111 - 282,724,300 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01290,049,251 - 290,066,163 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map19p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Ces2el1
9 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat

Markers in Region
D19Rat86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21260,432,881 - 260,433,115 (+)MAPPERmRatBN7.2
Rnor_6.01282,722,597 - 282,722,827NCBIRnor6.0
Rnor_5.01290,055,940 - 290,056,170UniSTSRnor5.0
Celera1926,390 - 26,613UniSTS
SHRSP x BN Map191.11RGD
SHRSP x BN Map191.11UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000073241   ⟹   ENSRNOP00000065593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1928,520 - 37,732 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1282,723,111 - 282,724,300 (+)Ensembl
RefSeq Acc Id: XM_039098090   ⟹   XP_038954018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81934,976 - 44,238 (-)NCBI
mRatBN7.21928,516 - 37,772 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001418901 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954018 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_038954018   ⟸   XM_039098090
- UniProtKB: A0A8L2QWT9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000065593   ⟸   ENSRNOT00000073241

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R8J8-F1-model_v2 AlphaFold M0R8J8 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587637 AgrOrtholog
BioCyc Gene G2FUF-6679 BioCyc
Ensembl Genes ENSRNOG00000048823 Ensembl
  ENSRNOG00000055064 Ensembl
NCBI Gene 688542 ENTREZGENE
PhenoGen Ces2el1 PhenoGen
RatGTEx ENSRNOG00000048823 RatGTEx
  ENSRNOG00000055064 RatGTEx
UniProt A0A8L2QWT9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ces2el1  carboxylesterase 2E like 1  LOC688542  similar to carboxylesterase 5  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC688542  similar to carboxylesterase 5  AABR07007146.1    Data merged from RGD:15005611 737654 PROVISIONAL
2021-03-09 LOC688542  similar to carboxylesterase 5  LOC102551636  uncharacterized LOC102551636  Data merged from RGD:7530537 737654 PROVISIONAL
2019-11-08 AABR07007146.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2013-12-17 LOC102551636  uncharacterized LOC102551636      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC688542  similar to carboxylesterase 5  LOC688542  similar to carboxylesterase 5  Gene reactivated at release of RGSC5.0 assembly 2298974 REACTIVATED
2006-11-19 LOC688542  similar to carboxylesterase 5      Symbol and Name status set to provisional 70820 PROVISIONAL