Abcc12 (ATP binding cassette subfamily C member 12) - Rat Genome Database

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Gene: Abcc12 (ATP binding cassette subfamily C member 12) Rattus norvegicus
Analyze
Symbol: Abcc12
Name: ATP binding cassette subfamily C member 12
RGD ID: 735100
Description: Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in endoplasmic reticulum. Predicted to be active in membrane. Orthologous to human ABCC12 (ATP binding cassette subfamily C member 12); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; INTERACTS WITH bisphenol A; furan; trichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-binding cassette protein C12; ATP-binding cassette protein C12 variant A; ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; ATP-binding cassette, subfamily C (CFTR/MRP), member 12; multidrug resistance-associated protein 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21920,549,298 - 20,621,991 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1922,234,945 - 22,302,213 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01927,429,457 - 27,496,732 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01930,392,245 - 30,459,522 (+)NCBIRnor_WKY
Rnor_6.01921,541,324 - 21,612,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01932,551,209 - 32,622,321 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41921,889,228 - 21,962,766 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11921,894,053 - 21,967,592 (+)NCBI
Celera1920,420,742 - 20,491,622 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12. Shimizu H, etal., Gene 2003 May 22;310:17-28.
Additional References at PubMed
PMID:18614015  


Genomics

Comparative Map Data
Abcc12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21920,549,298 - 20,621,991 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1922,234,945 - 22,302,213 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01927,429,457 - 27,496,732 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01930,392,245 - 30,459,522 (+)NCBIRnor_WKY
Rnor_6.01921,541,324 - 21,612,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01932,551,209 - 32,622,321 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41921,889,228 - 21,962,766 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11921,894,053 - 21,967,592 (+)NCBI
Celera1920,420,742 - 20,491,622 (+)NCBICelera
Cytogenetic Map19p11NCBI
ABCC12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381648,080,882 - 48,155,993 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1648,080,882 - 48,156,018 (-)EnsemblGRCh38hg38GRCh38
GRCh371648,114,793 - 48,189,904 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361646,674,385 - 46,738,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 341646,674,384 - 46,738,182NCBI
Celera1632,624,011 - 32,687,808 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1634,007,046 - 34,070,841 (-)NCBIHuRef
CHM1_11649,524,782 - 49,588,575 (-)NCBICHM1_1
T2T-CHM13v2.01653,877,688 - 53,952,799 (-)NCBIT2T-CHM13v2.0
Abcc12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39887,231,197 - 87,307,317 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl887,208,889 - 87,307,315 (-)EnsemblGRCm39 Ensembl
GRCm38886,504,568 - 86,580,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl886,482,260 - 86,580,686 (-)EnsemblGRCm38mm10GRCm38
MGSCv37889,028,740 - 89,090,489 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36889,394,946 - 89,456,695 (-)NCBIMGSCv36mm8
Celera890,773,129 - 90,826,830 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map842.06NCBI
Abcc12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554747,166,150 - 7,238,033 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554747,166,148 - 7,238,013 (+)NCBIChiLan1.0ChiLan1.0
ABCC12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11647,243,900 - 47,316,549 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1647,244,280 - 47,306,984 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01628,352,284 - 28,425,135 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ABCC12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,885,272 - 66,967,963 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,885,042 - 66,968,060 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha263,461,458 - 63,544,137 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,443,767 - 67,526,459 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,443,562 - 67,526,556 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1264,256,791 - 64,339,454 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0265,280,662 - 65,363,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,168,371 - 66,251,101 (+)NCBIUU_Cfam_GSD_1.0
Abcc12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934958,188,099 - 58,257,885 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364751,331,887 - 1,391,535 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364751,331,887 - 1,391,535 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl636,557,290 - 36,649,715 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1636,559,645 - 36,653,044 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ABCC12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1533,883,283 - 33,946,742 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl533,883,290 - 33,945,808 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604742,582,955 - 42,646,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcc12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249141,732,060 - 1,795,027 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249141,731,541 - 1,806,400 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abcc12
428 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:47
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000021095, ENSRNOT00000042077
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 10 3
Below cutoff 9 5 4 3 4 2 3 30 4 22 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY188179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY188180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021095   ⟹   ENSRNOP00000021095
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)Ensembl
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000042077   ⟹   ENSRNOP00000044842
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1920,549,405 - 20,620,492 (+)Ensembl
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensembl
RefSeq Acc Id: NM_199377   ⟹   NP_955409
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,405 - 20,620,492 (+)NCBI
Rnor_6.01921,541,742 - 21,612,527 (+)NCBI
Rnor_5.01932,551,209 - 32,622,321 (+)NCBI
RGSC_v3.41921,889,228 - 21,962,766 (+)RGD
Celera1920,420,742 - 20,491,622 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255241   ⟹   XP_006255303
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,326 - 21,612,757 (+)NCBI
Rnor_5.01932,551,209 - 32,622,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006255242   ⟹   XP_006255304
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,326 - 21,612,757 (+)NCBI
Rnor_5.01932,551,209 - 32,622,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772375   ⟹   XP_008770597
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,325 - 21,612,757 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772376   ⟹   XP_008770598
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,326 - 21,612,757 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097573   ⟹   XP_038953501
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
RefSeq Acc Id: XM_039097574   ⟹   XP_038953502
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,615,553 (+)NCBI
RefSeq Acc Id: XM_039097575   ⟹   XP_038953503
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,608,278 (+)NCBI
RefSeq Acc Id: XM_039097576   ⟹   XP_038953504
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,608,330 (+)NCBI
RefSeq Acc Id: XM_039097577   ⟹   XP_038953505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,572,205 - 20,620,761 (+)NCBI
RefSeq Acc Id: XR_005496627
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,621,991 (+)NCBI
RefSeq Acc Id: XR_005496628
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,619,790 (+)NCBI
RefSeq Acc Id: XR_005496629
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21920,549,298 - 20,593,196 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_955409   ⟸   NM_199377
- UniProtKB: Q6Y305 (UniProtKB/Swiss-Prot),   Q6Y306 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006255303   ⟸   XM_006255241
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006255304   ⟸   XM_006255242
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008770597   ⟸   XM_008772375
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008770598   ⟸   XM_008772376
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000021095   ⟸   ENSRNOT00000021095
RefSeq Acc Id: ENSRNOP00000044842   ⟸   ENSRNOT00000042077
RefSeq Acc Id: XP_038953501   ⟸   XM_039097573
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953502   ⟸   XM_039097574
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953504   ⟸   XM_039097576
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038953503   ⟸   XM_039097575
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038953505   ⟸   XM_039097577
- Peptide Label: isoform X8
Protein Domains
ABC transmembrane type-1   ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6Y306-F1-model_v2 AlphaFold Q6Y306 1-1366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700987
Promoter ID:EPDNEW_R11510
Type:single initiation site
Name:Abcc12_1
Description:ATP binding cassette subfamily C member 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01921,541,691 - 21,541,751EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735100 AgrOrtholog
BioCyc Gene G2FUF-6226 BioCyc
Ensembl Genes ENSRNOG00000015666 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021095.4 UniProtKB/TrEMBL
  ENSRNOP00000044842 ENTREZGENE
  ENSRNOP00000044842.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021095.6 UniProtKB/TrEMBL
  ENSRNOT00000042077 ENTREZGENE
  ENSRNOT00000042077.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291923 UniProtKB/Swiss-Prot
NCBI Gene 291923 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24223:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abcc12 PhenoGen
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3ZIZ6_RAT UniProtKB/TrEMBL
  F1M7G9_RAT UniProtKB/TrEMBL
  MRP9_RAT UniProtKB/Swiss-Prot
  Q6Y305 ENTREZGENE
  Q6Y306 ENTREZGENE
UniProt Secondary Q6Y305 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Abcc12  ATP binding cassette subfamily C member 12  Abcc12  ATP-binding cassette, subfamily C (CFTR/MRP), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-16 Abcc12  ATP-binding cassette, subfamily C (CFTR/MRP), member 12  Abcc12  ATP-binding cassette, sub-family C (CFTR/MRP), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Abcc12  ATP-binding cassette, sub-family C (CFTR/MRP), member 12    ATP-binding cassette protein C12  Name updated 1299863 APPROVED