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Gene: Cx3cl1 (C-X3-C motif chemokine ligand 1) Rattus norvegicus
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Symbol: Cx3cl1
Name: C-X3-C motif chemokine ligand 1
Description: Exhibits chemokine activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of neurogenesis; and regulation of signal transduction. Localizes to several cellular components, including the neuron projection; neuronal cell body; and perinuclear region of cytoplasm. Used to study acute pancreatitis; ischemia; and status epilepticus. Biomarker of several diseases, including borna disease; brain disease (multiple); liver disease (multiple); lung disease (multiple); and pulmonary hypertension. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-X3-C motif chemokine 1; chemokine (C-X3-C motif) ligand 1; Cx3c; CX3C membrane-anchored chemokine; fractalkine; neurotactin; Scyd1; small inducible cytokine subfamily D 1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1
Orthologs:
Homo sapiens (human) : CX3CL1 (C-X3-C motif chemokine ligand 1)  HGNC  Alliance
Mus musculus (house mouse) : Cx3cl1 (chemokine (C-X3-C motif) ligand 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Canis lupus familiaris (dog) : CX3CL1 (C-X3-C motif chemokine ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cx3cl1 (C-X3-C motif chemokine ligand 1)
Sus scrofa (pig) : CX3CL1 (C-X3-C motif chemokine ligand 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01910,644,267 - 10,654,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,644,244 - 10,653,800 (-)Ensembl
Rnor_5.01910,638,466 - 10,647,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,666,940 - 10,676,424 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11910,671,765 - 10,681,250 (-)NCBI
Celera1910,113,300 - 10,122,786 (-)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cx3cl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620458
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.