Cx3cl1 (chemokine (C-X3-C motif) ligand 1) - Rat Genome Database

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Gene: Cx3cl1 (chemokine (C-X3-C motif) ligand 1) Mus musculus
Analyze
Symbol: Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
RGD ID: 731691
MGI Page MGI
Description: Exhibits chemokine activity. Involved in several processes, including angiogenesis involved in wound healing; leukocyte chemotaxis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to several cellular components, including cell surface; neuron projection; and neuronal cell body. Is expressed in several structures, including brain; genitourinary system; gut; nose; and respiratory system. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AB030188; ABCD-3; AI848747; C-X3-C motif chemokine 1; CX3C; CX3C membrane-anchored chemokine; Cxc3; D8Bwg0439e; fract; fractalkine; neuro; neurotactin; Scyd; Scyd1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,498,808 - 95,509,055 (+)NCBIGRCm39mm39
GRCm39 Ensembl895,498,637 - 95,509,055 (+)Ensembl
GRCm38894,772,180 - 94,782,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,772,009 - 94,782,427 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,296,080 - 97,306,327 (+)NCBIGRCm37mm9NCBIm37
MGSCv36897,661,355 - 97,671,556 (+)NCBImm8
Celera899,100,414 - 99,110,655 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-diaminotoluene  (EXP)
2-acetamidofluorene  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-hydroxyphenyl retinamide  (EXP)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (EXP,ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aripiprazole  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
asperentin  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
ceric oxide  (ISO)
chloroprene  (ISO)
choline  (EXP)
chromium atom  (ISO)
ciguatoxin CTX1B  (EXP)
clofibrate  (ISO)
cobalt atom  (EXP)
cocaine  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzacamene  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
folic acid  (EXP)
fructose  (ISO)
furan  (ISO)
gamma-aminobutyric acid  (ISO)
glucose  (ISO)
graphene oxide  (EXP)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
ketamine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP,ISO)
manganese(II) chloride  (ISO)
mechlorethamine  (ISO)
methadone  (ISO)
methylmercury chloride  (EXP)
mifepristone  (ISO)
morphine  (ISO)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naproxen  (ISO)
neoechinulin A  (EXP)
nickel atom  (EXP,ISO)
nickel dichloride  (ISO)
ozone  (ISO)
p-cresol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium dichromate  (ISO)
progesterone  (EXP,ISO)
quercetin  (ISO)
resveratrol  (ISO)
rofecoxib  (ISO)
rutin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sterigmatocystin  (EXP)
sumatriptan  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis involved in wound healing  (IMP)
autocrine signaling  (ISO)
cell adhesion  (ISO)
cell chemotaxis  (ISO)
cell-cell adhesion  (ISO)
cellular response to interferon-gamma  (IBA)
cellular response to interleukin-1  (IBA)
cellular response to tumor necrosis factor  (IBA)
chemokine-mediated signaling pathway  (IBA,ISO)
chemotaxis  (ISO)
cytokine-mediated signaling pathway  (IMP)
eosinophil chemotaxis  (IBA)
G protein-coupled receptor signaling pathway  (IBA,ISO)
immune response  (IEA)
inflammatory response  (IBA)
inhibitory postsynaptic potential  (ISO)
integrin activation  (ISO)
leukocyte adhesive activation  (IEA)
leukocyte migration involved in inflammatory response  (ISO)
lymphocyte chemotaxis  (IBA,IDA)
macrophage chemotaxis  (IMP)
microglial cell activation  (ISO)
microglial cell proliferation  (ISO)
monocyte chemotaxis  (IBA)
negative regulation of apoptotic process  (ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IDA)
negative regulation of glutamate receptor signaling pathway  (ISO)
negative regulation of hippocampal neuron apoptotic process  (ISO)
negative regulation of interleukin-1 alpha production  (ISO)
negative regulation of microglial cell activation  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
negative regulation of vasoconstriction  (ISO)
neuron cellular homeostasis  (ISO)
neutrophil chemotaxis  (IBA,IDA)
platelet activation  (ISO)
positive chemotaxis  (ISO)
positive regulation of actin filament bundle assembly  (ISO)
positive regulation of angiogenesis  (IMP)
positive regulation of calcium-independent cell-cell adhesion  (ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA)
positive regulation of GTPase activity  (IBA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of I-kappaB phosphorylation  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of macrophage chemotaxis  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of microglial cell migration  (ISO)
positive regulation of neuroblast proliferation  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of release of sequestered calcium ion into cytosol  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transforming growth factor beta1 production  (IMP)
regulation of lipopolysaccharide-mediated signaling pathway  (ISO)
response to hypoxia  (ISO)
response to ischemia  (ISO)
wound healing  (IMP)

Cellular Component

Molecular Function

References

References - curated
1. Ars C, etal., Eur Respir J. 2009 Dec;34(6):1494-6.
2. Avni T, etal., Cytokine. 2010 Dec;52(3):143-5.
3. Bradesi S, etal., Gastroenterology. 2008 Dec 24.
4. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
5. Briones TL, etal., J Neuroinflammation. 2014 Jan 22;11:13. doi: 10.1186/1742-2094-11-13.
6. Chen YM, etal., Nephrol Dial Transplant. 2003 Dec;18(12):2505-14.
7. Chu L, etal., Ophthalmic Res. 2009;42(3):160-6. Epub 2009 Jul 31.
8. Date T, etal., Circ J. 2009 May;73(5):932-7. Epub 2009 Mar 12.
9. Eccles R, etal., Respir Res. 2010 Aug 10;11:108.
10. Echigo T, etal., J Allergy Clin Immunol. 2004 May;113(5):940-8.
11. Fang IM, etal., Mol Vis. 2005 Jul 1;11:443-51.
12. Hasegawa M, etal., Ann Rheum Dis. 2005 Jan;64(1):21-8.
13. Herd KA, etal., J Gen Virol. 2010 May;91(Pt 5):1302-10. Epub 2010 Jan 6.
14. Huang LY, etal., Inflammation. 2012 Jun;35(3):1023-30. doi: 10.1007/s10753-011-9406-5.
15. Hughes PM, etal., Glia. 2002 Mar 15;37(4):314-27.
16. Ito Y, etal., Kidney Int. 2002 Jun;61(6):2044-57.
17. Ji JF, etal., Stem Cells. 2004;22(3):415-27.
18. Katsuyama K, etal., Nephron Exp Nephrol. 2009;113(2):e45-56. Epub 2009 Jul 10.
19. Kikuchi T, etal., Infect Immun. 2005 Sep;73(9):5350-7.
20. Kikuchi Y, etal., Nephron Exp Nephrol. 2004;97(1):e17-25.
21. Landi A, etal., Cytokine. 2016 Feb;78:27-36. doi: 10.1016/j.cyto.2015.11.018. Epub 2015 Nov 28.
22. Li L, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010 Apr;30(4):373-5.
23. Luongo L, etal., Neurosci Lett. 2008 May 30;437(2):98-102. Epub 2008 Apr 10.
24. Matsunawa M, etal., Clin Exp Rheumatol. 2009 Jan-Feb;27(1):72-8.
25. McComb JG, etal., Am J Pathol. 2008 Oct;173(4):949-61. Epub 2008 Sep 4.
26. Merino J, etal., Dig Dis Sci. 2011 Aug;56(8):2309-17. doi: 10.1007/s10620-011-1625-y. Epub 2011 Feb 24.
27. MGD and Homologene mouse data transfer
28. MGD data from the GO Consortium
29. MGD IEA
30. Morimura S, etal., Am J Pathol. 2013 May;182(5):1640-7. doi: 10.1016/j.ajpath.2013.01.023. Epub 2013 Mar 5.
31. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
32. Park HW, etal., Spine (Phila Pa 1976). 2011 Jan 8.
33. Rauer M, etal., J Neurovirol. 2002 Jan;8(3):168-79.
34. RGD automated import pipeline
35. RGD automated import pipeline for gene-chemical interactions
36. Rimaniol AC, etal., J Allergy Clin Immunol. 2003 Dec;112(6):1139-46.
37. Ruth JH, etal., Arthritis Rheum. 2001 Jul;44(7):1568-81.
38. Ryu J, etal., Cardiovasc Res. 2008 May 1;78(2):333-40. Epub 2007 Nov 11.
39. Shan S, etal., Neurobiol Aging. 2009 Apr 14.
40. Sun C, etal., Zhonghua Yi Xue Za Zhi. 2013 Jan 1;93(1):69-72.
41. Sun S, etal., Mol Neurobiol. 2014 May 1.
42. Sunnemark D, etal., J Neuroinflammation. 2005 Jul 29;2:17.
43. Suzuki F, etal., Arthritis Res Ther. 2012 Mar 6;14(2):R48. doi: 10.1186/ar3761.
44. Wang L, etal., Int Endod J. 2014 Mar;47(3):271-9. doi: 10.1111/iej.12143. Epub 2013 Jul 6.
45. Wang L, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Jan;27(1):55-9.
46. Yang JL, etal., Mol Brain. 2012 May 30;5:18. doi: 10.1186/1756-6606-5-18.
47. Yeo SI, etal., J Neuroimmunol. 2011 May;234(1-2):93-102. doi: 10.1016/j.jneuroim.2011.03.005. Epub 2011 Apr 8.
48. Yoshida T, etal., Cardiovasc Res. 2005 Nov 1;68(2):278-88. Epub 2005 Jul 12.
49. Yuridullah R, etal., Auton Neurosci. 2006 Jun 30;126-127:380-9. Epub 2006 May 2.
50. Zhang J, etal., J Hepatol. 2012 Oct;57(4):752-8. doi: 10.1016/j.jhep.2012.05.014. Epub 2012 May 29.
51. Zheng BX, etal., Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 Mar;39(2):227-30.
52. Zhu J, etal., Brain Res. 2009 Sep 1;1287:173-83. Epub 2009 Jun 27.
Additional References at PubMed
PMID:8889548   PMID:9177350   PMID:9479488   PMID:9845323   PMID:10349636   PMID:10382755   PMID:10679242   PMID:10822268   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11287620  
PMID:11472060   PMID:11688560   PMID:11960641   PMID:12080938   PMID:12126650   PMID:12477932   PMID:12569158   PMID:12815711   PMID:14514721   PMID:15381731   PMID:15529011   PMID:15557198  
PMID:15596719   PMID:15748167   PMID:16141072   PMID:16141073   PMID:16148119   PMID:16272359   PMID:16602821   PMID:16675847   PMID:16732273   PMID:16751386   PMID:16804897   PMID:16893423  
PMID:17053165   PMID:17332365   PMID:17372897   PMID:17917825   PMID:17963723   PMID:17971299   PMID:18003857   PMID:18095157   PMID:18097059   PMID:18098313   PMID:18165355   PMID:18287559  
PMID:18322241   PMID:18490761   PMID:18497708   PMID:18565216   PMID:18682600   PMID:18799722   PMID:18951638   PMID:18971423   PMID:19709758   PMID:19745110   PMID:19850645   PMID:19923448  
PMID:19934081   PMID:20041188   PMID:20200508   PMID:20335311   PMID:20347720   PMID:20410215   PMID:20570369   PMID:20683935   PMID:21071446   PMID:21131421   PMID:21267068   PMID:21388954  
PMID:21451526   PMID:21677750   PMID:21840883   PMID:21873635   PMID:21951685   PMID:22072684   PMID:22093090   PMID:22564616   PMID:22564617   PMID:22573666   PMID:22739755   PMID:22815945  
PMID:22883932   PMID:22916279   PMID:23002075   PMID:23026294   PMID:23077045   PMID:23100431   PMID:23117657   PMID:23653073   PMID:23720051   PMID:23724129   PMID:23936109   PMID:23981568  
PMID:24006262   PMID:24161906   PMID:24362517   PMID:24401612   PMID:24655482   PMID:24700421   PMID:24788416   PMID:24821910   PMID:24952961   PMID:25191897   PMID:25195598   PMID:25209291  
PMID:25375377   PMID:25495686   PMID:25768734   PMID:25966946   PMID:26469270   PMID:26555704   PMID:26670885   PMID:26765996   PMID:26802470   PMID:26864305   PMID:26976687   PMID:27314452  
PMID:27339271   PMID:27378696   PMID:27579490   PMID:27687148   PMID:27832289   PMID:27942903   PMID:28125278   PMID:28472653   PMID:28612258   PMID:28800592   PMID:29356931   PMID:29669747  
PMID:29750189   PMID:29798841   PMID:29925374   PMID:30253780   PMID:30399192   PMID:30675063   PMID:30948201   PMID:31134047   PMID:31209068   PMID:31209379   PMID:31446159   PMID:31822518  
PMID:32410624   PMID:33034881   PMID:33325803  


Genomics

Comparative Map Data
Cx3cl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,498,808 - 95,509,055 (+)NCBIGRCm39mm39
GRCm39 Ensembl895,498,637 - 95,509,055 (+)Ensembl
GRCm38894,772,180 - 94,782,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,772,009 - 94,782,427 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,296,080 - 97,306,327 (+)NCBIGRCm37mm9NCBIm37
MGSCv36897,661,355 - 97,671,556 (+)NCBImm8
Celera899,100,414 - 99,110,655 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.79NCBI
CX3CL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1657,372,477 - 57,385,044 (+)EnsemblGRCh38hg38GRCh38
GRCh381657,372,490 - 57,385,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371657,406,402 - 57,418,956 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,963,915 - 55,976,457 (+)NCBINCBI36hg18NCBI36
Build 341655,963,914 - 55,976,455NCBI
Celera1641,906,410 - 41,918,956 (+)NCBI
Cytogenetic Map16q21NCBI
HuRef1643,274,294 - 43,286,836 (+)NCBIHuRef
CHM1_11658,814,588 - 58,827,172 (+)NCBICHM1_1
Cx3cl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21910,227,337 - 10,237,826 (-)NCBI
Rnor_6.0 Ensembl1910,644,244 - 10,653,800 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01910,644,267 - 10,654,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01910,638,466 - 10,647,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,666,940 - 10,676,424 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11910,671,765 - 10,681,250 (-)NCBI
Celera1910,113,300 - 10,122,786 (-)NCBICelera
Cytogenetic Map19p13NCBI
Cx3cl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,023,050 - 15,034,711 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,023,272 - 15,034,650 (+)NCBIChiLan1.0ChiLan1.0
CX3CL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11656,779,065 - 56,791,760 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1656,779,065 - 56,791,760 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01637,646,447 - 37,659,078 (+)NCBIMhudiblu_PPA_v0panPan3
CX3CL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,022,794 - 59,032,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,022,794 - 59,032,095 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,652,232 - 55,661,533 (-)NCBI
ROS_Cfam_1.0259,561,127 - 59,570,437 (-)NCBI
UMICH_Zoey_3.1256,392,704 - 56,402,005 (-)NCBI
UNSW_CanFamBas_1.0257,400,382 - 57,409,687 (-)NCBI
UU_Cfam_GSD_1.0258,293,678 - 58,302,979 (-)NCBI
Cx3cl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,134,360 - 50,145,250 (-)NCBI
SpeTri2.0NW_0049364759,443,851 - 9,454,715 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CX3CL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1619,312,351 - 19,324,439 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,304,118 - 17,315,820 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233058
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,310,711 - 43,323,533 (+)NCBI
ChlSab1.1 Ensembl543,310,753 - 43,323,529 (+)Ensembl
Vero_WHO_p1.0NW_02366604732,993,345 - 33,006,077 (-)NCBI
Cx3cl1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474628,677,956 - 28,688,638 (-)NCBI

Position Markers
Cx3cl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
AF010586  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,780,576 - 94,780,672UniSTSGRCm38
MGSCv37897,304,476 - 97,304,572UniSTSGRCm37
Celera899,108,807 - 99,108,903UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
Whitehead/MRC_RH81151.8UniSTS
AI848747  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,781,986 - 94,782,106UniSTSGRCm38
MGSCv37897,305,886 - 97,306,006UniSTSGRCm37
Celera899,110,214 - 99,110,334UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
Whitehead/MRC_RH81151.8UniSTS
U92565  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,781,715 - 94,781,862UniSTSGRCm38
MGSCv37897,305,615 - 97,305,762UniSTSGRCm37
Celera899,109,946 - 99,110,093UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
Whitehead/MRC_RH81151.8UniSTS
RH125207  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,782,163 - 94,782,258UniSTSGRCm38
MGSCv37897,306,063 - 97,306,158UniSTSGRCm37
Celera899,110,391 - 99,110,486UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
PMC127832P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,780,199 - 94,780,556UniSTSGRCm38
MGSCv37897,304,099 - 97,304,456UniSTSGRCm37
Celera899,108,430 - 99,108,787UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
UniSTS:224536  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,782,173 - 94,782,331UniSTSGRCm38
MGSCv37897,306,073 - 97,306,231UniSTSGRCm37
Celera899,110,401 - 99,110,559UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
PMC86945P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,779,577 - 94,779,787UniSTSGRCm38
MGSCv37897,303,477 - 97,303,687UniSTSGRCm37
Celera899,107,808 - 99,108,018UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS
Scyd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38894,782,166 - 94,782,333UniSTSGRCm38
MGSCv37897,306,066 - 97,306,233UniSTSGRCm37
Celera899,110,394 - 99,110,561UniSTS
Cytogenetic Map8C5UniSTS
cM Map846.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse
1301766Desp1_mdespair 1 (mouse)Not determined884759576118759741Mouse
1302049Heal1_mwound healing/regeneration 1 (mouse)Not determined885716921119717069Mouse
1301253Skmw2_mskeletal muscle weight 2 (mouse)Not determined885716921119717069Mouse
10045619Heal14_mwound healing/regeneration 14 (mouse)Not determined885716921119717069Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889000000130800000Mouse
14696809Rbcn3_mrod bipolar cell number 3 (mouse)894330000102130000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1269
Count of miRNA genes:622
Interacting mature miRNAs:768
Transcripts:ENSMUST00000034230, ENSMUST00000135970, ENSMUST00000150307, ENSMUST00000151783
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB030188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF010586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF071549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB526167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034230   ⟹   ENSMUSP00000034230
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,009 - 94,782,427 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135970   ⟹   ENSMUSP00000117632
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,204 - 94,779,638 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150307   ⟹   ENSMUSP00000123538
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,225 - 94,780,022 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151783
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,204 - 94,778,945 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211947   ⟹   ENSMUSP00000148534
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,204 - 94,779,805 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211956   ⟹   ENSMUSP00000148819
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl894,772,204 - 94,778,366 (+)Ensembl
RefSeq Acc Id: NM_009142   ⟹   NP_033168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39895,498,808 - 95,509,055 (+)NCBI
GRCm38894,772,180 - 94,782,427 (+)ENTREZGENE
MGSCv37897,296,080 - 97,306,327 (+)RGD
Celera899,100,414 - 99,110,655 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033168   ⟸   NM_009142
- Peptide Label: precursor
- UniProtKB: O35188 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000123538   ⟸   ENSMUST00000150307
RefSeq Acc Id: ENSMUSP00000148534   ⟸   ENSMUST00000211947
RefSeq Acc Id: ENSMUSP00000148819   ⟸   ENSMUST00000211956
RefSeq Acc Id: ENSMUSP00000034230   ⟸   ENSMUST00000034230
RefSeq Acc Id: ENSMUSP00000117632   ⟸   ENSMUST00000135970
Protein Domains
SCY

Promoters
RGD ID:8667915
Promoter ID:EPDNEW_M11989
Type:multiple initiation site
Name:Cx3cl1_1
Description:Mus musculus chemokine (C-X3-C motif) ligand 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38894,772,204 - 94,772,264EPDNEW
RGD ID:6842981
Promoter ID:MM_KWN:55348
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000074188,   OTTMUST00000074189,   OTTMUST00000074190,   OTTMUST00000074191
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36897,295,841 - 97,296,341 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097153 AgrOrtholog
Ensembl Genes ENSMUSG00000031778 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034230 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117632 UniProtKB/TrEMBL
  ENSMUSP00000123538 UniProtKB/TrEMBL
  ENSMUSP00000148534 UniProtKB/TrEMBL
  ENSMUSP00000148819 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034230 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000135970 UniProtKB/TrEMBL
  ENSMUST00000150307 UniProtKB/TrEMBL
  ENSMUST00000211947 UniProtKB/TrEMBL
  ENSMUST00000211956 UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CX3C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CX3CL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20312 UniProtKB/Swiss-Prot
MGD MGI:1097153 ENTREZGENE
NCBI Gene 20312 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12015:SF92 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cx3cl1 PhenoGen
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1D5RLW9_MOUSE UniProtKB/TrEMBL
  A0A1D5RMK8_MOUSE UniProtKB/TrEMBL
  D6RCV0_MOUSE UniProtKB/TrEMBL
  E0CXC3_MOUSE UniProtKB/TrEMBL
  O35188 ENTREZGENE
  Q8C9Y1_MOUSE UniProtKB/TrEMBL
  Q9JMF8_MOUSE UniProtKB/TrEMBL
  X3CL1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O35933 UniProtKB/Swiss-Prot
  Q91V44 UniProtKB/Swiss-Prot