Cdh5 (cadherin 5) - Rat Genome Database

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Gene: Cdh5 (cadherin 5) Rattus norvegicus
Analyze
Symbol: Cdh5
Name: cadherin 5
RGD ID: 1307370
Description: Predicted to enable several functions, including beta-catenin binding activity; enzyme binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell junction organization; and regulation of protein-containing complex assembly. Predicted to act upstream of or within blood vessel maturation; cell-cell adhesion; and negative regulation of cell population proliferation. Predicted to be located in several cellular components, including cell-cell junction; external side of plasma membrane; and nucleus. Predicted to be part of catenin complex. Predicted to be active in adherens junction and bicellular tight junction. Biomarker of pulmonary hypertension. Orthologous to human CDH5 (cadherin 5); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cadherin-5; LOC307618; vascular endothelial cadherin; VE-cadherin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr819821,875 - 860,931 (-)NCBIGRCr8
mRatBN7.219815,415 - 854,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19815,411 - 854,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx19813,201 - 850,834 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,580,002 - 1,617,637 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019855,206 - 892,839 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,025,122 - 1,074,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,023,683 - 1,074,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0191,022,710 - 1,072,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419779,350 - 816,108 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119779,507 - 1,129,968 (-)NCBI
Celera19805,477 - 843,688 (-)NCBICelera
Cytogenetic Map19p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
26-hydroxycholesterol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acetic acid  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-D-galactose  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
aripiprazole  (ISO)
arsenous acid  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Bis-(1-chloro-2-propyl) phosphate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
cantharidin  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
columbamine  (ISO)
cortisol  (ISO)
cumene  (ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
digitonin  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
furosemide  (EXP)
galactose  (ISO)
glucose  (ISO)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
jaspamide  (ISO)
kaempferol  (ISO)
lipopolysaccharide  (ISO)
luteolin  (EXP)
lycorine  (ISO)
mercury dichloride  (ISO)
methamphetamine  (EXP)
methyllycaconitine  (ISO)
monocrotaline  (EXP)
N-acetyl-L-cysteine  (ISO)
N-Acetylleucyl-leucyl-methioninal  (ISO)
Octicizer  (ISO)
oroxylin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorododecanoic acid  (ISO)
perfluoroheptanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanesulfonamide  (ISO)
permethrin  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
procaine  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
tributyl phosphate  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
valproic acid  (ISO)
varenicline  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adherens junction organization  (IBA,ISO)
bicellular tight junction assembly  (ISO)
blood vessel endothelial cell migration  (ISO)
blood vessel maturation  (ISO)
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  (IBA)
cell migration  (IBA)
cell morphogenesis  (IBA)
cell surface receptor signaling pathway  (ISO)
cell-cell adhesion  (ISO)
cell-cell adhesion mediated by cadherin  (IBA,ISO)
cell-cell junction assembly  (IBA,ISO)
endothelial cell morphogenesis  (ISO)
homophilic cell adhesion via plasma membrane adhesion molecules  (IEA)
intracellular calcium ion homeostasis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of endothelial cell apoptotic process  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of microtubule polymerization  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of establishment of endothelial barrier  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of intracellular signal transduction  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
protein localization to bicellular tight junction  (ISO)
regulation of complement-dependent cytotoxicity  (ISO)
regulation of establishment of cell polarity  (ISO)
regulation of vascular permeability  (ISO)
transforming growth factor beta receptor signaling pathway  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Endothelial-to-mesenchymal transition in pulmonary hypertension. Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients. Shuwen H, etal., Dis Markers. 2020 Jun 16;2020:9369341. doi: 10.1155/2020/9369341. eCollection 2020.
10. Elevated concentration of soluble vascular endothelial cadherin is associated with coronary atherosclerosis. Soeki T, etal., Circ J. 2004 Jan;68(1):1-5.
Additional References at PubMed
PMID:10508865   PMID:11950700   PMID:12088286   PMID:15572031   PMID:15855637   PMID:15861137   PMID:16455951   PMID:16973135   PMID:17060906   PMID:17536065   PMID:18287330   PMID:19129494  
PMID:19413351   PMID:19635461   PMID:19996314   PMID:20332120   PMID:20711984   PMID:21037229   PMID:21168935   PMID:21738954   PMID:21884682   PMID:22391569   PMID:23159740   PMID:23288152  
PMID:23417864   PMID:24280217   PMID:24778164   PMID:25753039   PMID:25893857   PMID:25978380   PMID:26133549   PMID:26551054   PMID:26598555   PMID:26847917   PMID:26923917   PMID:27233997  
PMID:28112401   PMID:28926625   PMID:29749551   PMID:30995547   PMID:31934175  


Genomics

Comparative Map Data
Cdh5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr819821,875 - 860,931 (-)NCBIGRCr8
mRatBN7.219815,415 - 854,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19815,411 - 854,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx19813,201 - 850,834 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,580,002 - 1,617,637 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019855,206 - 892,839 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,025,122 - 1,074,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,023,683 - 1,074,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0191,022,710 - 1,072,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419779,350 - 816,108 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119779,507 - 1,129,968 (-)NCBI
Celera19805,477 - 843,688 (-)NCBICelera
Cytogenetic Map19p14NCBI
CDH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381666,366,691 - 66,404,784 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1666,366,690 - 66,404,784 (+)EnsemblGRCh38hg38GRCh38
GRCh371666,400,594 - 66,438,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361664,958,064 - 64,996,190 (+)NCBINCBI36Build 36hg18NCBI36
Build 341664,958,063 - 64,996,189NCBI
Celera1650,909,482 - 50,944,587 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1652,277,104 - 52,314,656 (+)NCBIHuRef
CHM1_11667,807,788 - 67,845,939 (+)NCBICHM1_1
T2T-CHM13v2.01672,161,057 - 72,198,985 (+)NCBIT2T-CHM13v2.0
Cdh5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398104,828,247 - 104,871,136 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8104,828,257 - 104,871,143 (+)EnsemblGRCm39 Ensembl
GRCm388104,101,613 - 104,144,504 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8104,101,625 - 104,144,511 (+)EnsemblGRCm38mm10GRCm38
MGSCv378106,625,525 - 106,668,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368106,990,828 - 107,033,630 (+)NCBIMGSCv36mm8
Celera8108,332,486 - 108,375,834 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Cdh5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543322,967,960 - 22,992,924 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543322,957,718 - 22,994,515 (+)NCBIChiLan1.0ChiLan1.0
CDH5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21875,868,996 - 75,907,239 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11681,781,113 - 81,819,347 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01646,684,545 - 46,722,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11665,787,426 - 65,825,360 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1665,787,370 - 65,825,360 (+)Ensemblpanpan1.1panPan2
CDH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,830,505 - 82,863,931 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,830,939 - 82,863,882 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,820,021 - 82,852,406 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0583,268,385 - 83,300,767 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl583,268,594 - 83,300,713 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1583,091,349 - 83,123,732 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,784,959 - 82,805,255 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0583,417,122 - 83,449,500 (-)NCBIUU_Cfam_GSD_1.0
Cdh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,814,114 - 42,850,388 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647516,738,748 - 16,775,123 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647516,738,772 - 16,775,000 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,108,597 - 27,142,177 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,108,560 - 27,142,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CDH5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1552,059,987 - 52,098,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl552,060,013 - 52,100,405 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604723,817,264 - 23,856,166 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474620,033,008 - 20,057,595 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474620,028,952 - 20,068,029 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdh5
257 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:40
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000017983
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat

Markers in Region
RH128436  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr819822,062 - 822,269 (+)Marker Load Pipeline
mRatBN7.219815,602 - 815,809 (+)MAPPERmRatBN7.2
Rnor_6.0191,023,878 - 1,024,084NCBIRnor6.0
Rnor_5.0191,021,466 - 1,021,672UniSTSRnor5.0
RGSC_v3.419778,105 - 778,311UniSTSRGSC3.4
Celera19804,238 - 804,444UniSTS
RH 3.4 Map190.0UniSTS
Cytogenetic Map19p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017983   ⟹   ENSRNOP00000017983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl19816,849 - 832,576 (-)Ensembl
Rnor_6.0 Ensembl191,025,122 - 1,074,333 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086995   ⟹   ENSRNOP00000071462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl19815,411 - 854,368 (-)Ensembl
Rnor_6.0 Ensembl191,023,683 - 1,074,365 (-)Ensembl
RefSeq Acc Id: NM_001107407   ⟹   NP_001100877
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr819823,307 - 860,822 (-)NCBI
mRatBN7.219816,849 - 854,368 (-)NCBI
Rnor_6.0191,025,122 - 1,074,333 (-)NCBI
Rnor_5.0191,022,710 - 1,072,784 (-)NCBI
RGSC_v3.419779,350 - 816,108 (-)RGD
Celera19805,477 - 843,688 (-)RGD
Sequence:
RefSeq Acc Id: XM_039097688   ⟹   XP_038953616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr819821,875 - 860,931 (-)NCBI
mRatBN7.219815,415 - 854,478 (-)NCBI
RefSeq Acc Id: XM_039097689   ⟹   XP_038953617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr819821,875 - 851,124 (-)NCBI
mRatBN7.219815,415 - 844,671 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100877 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953616 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953617 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL87251 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017983.7
  ENSRNOP00000071462.2
RefSeq Acc Id: NP_001100877   ⟸   NM_001107407
- UniProtKB: A6JXX3 (UniProtKB/TrEMBL),   F1M7E5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071462   ⟸   ENSRNOT00000086995
Ensembl Acc Id: ENSRNOP00000017983   ⟸   ENSRNOT00000017983
RefSeq Acc Id: XP_038953616   ⟸   XM_039097688
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0I6 (UniProtKB/TrEMBL),   F1M7E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953617   ⟸   XM_039097689
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0I6 (UniProtKB/TrEMBL),   F1M7E5 (UniProtKB/TrEMBL)
Protein Domains
Cadherin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M7E5-F1-model_v2 AlphaFold F1M7E5 1-776 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700915
Promoter ID:EPDNEW_R11439
Type:initiation region
Name:Cdh5_1
Description:cadherin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0191,074,345 - 1,074,405EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307370 AgrOrtholog
BioCyc Gene G2FUF-6632 BioCyc
Ensembl Genes ENSRNOG00000013324 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017983.7 UniProtKB/TrEMBL
  ENSRNOT00000086995.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin UniProtKB/TrEMBL
  Cadherin-like UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin_binding_dom UniProtKB/TrEMBL
KEGG Report rno:307618 UniProtKB/TrEMBL
NCBI Gene 307618 ENTREZGENE
PANTHER PTHR24027 UniProtKB/TrEMBL
  PTHR24027:SF89 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PhenoGen Cdh5 PhenoGen
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013324 RatGTEx
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP Cadherin UniProtKB/TrEMBL
UniProt A0A0G2K0I6 ENTREZGENE, UniProtKB/TrEMBL
  A6JXX3 ENTREZGENE, UniProtKB/TrEMBL
  F1M7E5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cdh5  cadherin 5   Cdh5_predicted  cadherin 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cdh5_predicted  cadherin 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED